MX9603879A - Composiciones aclaradoras de la piel. - Google Patents
Composiciones aclaradoras de la piel.Info
- Publication number
- MX9603879A MX9603879A MX9603879A MX9603879A MX9603879A MX 9603879 A MX9603879 A MX 9603879A MX 9603879 A MX9603879 A MX 9603879A MX 9603879 A MX9603879 A MX 9603879A MX 9603879 A MX9603879 A MX 9603879A
- Authority
- MX
- Mexico
- Prior art keywords
- alkyl
- hydroxy
- group
- hydrogen
- halo
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
- A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/347—Phenols
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/368—Carboxylic acids; Salts or anhydrides thereof with carboxyl groups directly bound to carbon atoms of aromatic rings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
- A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
- A61K8/466—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur containing sulfonic acid derivatives; Salts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4986—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with sulfur as the only hetero atom
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/55—Phosphorus compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/48—Preparation of compounds having groups
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/48—Preparation of compounds having groups
- C07C41/50—Preparation of compounds having groups by reactions producing groups
- C07C41/54—Preparation of compounds having groups by reactions producing groups by addition of compounds to unsaturated carbon-to-carbon bonds
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/30—Compounds having groups
- C07C43/315—Compounds having groups containing oxygen atoms singly bound to carbon atoms not being acetal carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/20—Oxygen atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/30—Hetero atoms other than halogen
- C07D333/32—Oxygen atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
- C07D335/02—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/582—Recycling of unreacted starting or intermediate materials
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Emergency Medicine (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Esta invencion se refiere a composiciones, compuestos y métodos para aclarar la piel, utilizando compuestos activos que tienen la estructura (I) o (II): en donde: (i) cada X se selecciona, independientemente, del grupo que consiste de halogeno, alquilo, alquilo substituido, arilo, OR, OCOR, COR, CONRR, COOR, CN, SR, SOR, SO2R, SO3R y NRR, en donde X es diferente de hidroxi, amino y tio, si esta X está unida a orto al fenol hidroxi; (ii) m es un entero de 0 a 4; (iii) cada R y cada R se selecciona, independientemente, del grupo que consiste de hidrogeno, halogeno, alquilo, alquilo substituido, arilo, OR, OCOR, OCRROR, COR, CR(OR)OR, CONRR, COOR, CRROR, CN, SR y NRR; en donde halogeno, cuando aparece, es diferente de geminal a hidroxi, NH2, o SH; (iv) R es alquilo o alquilo substituido; en donde cuando R está presente y R también es hidrogeno, R es diferente de hidrogeno, hidroxi, halogeno, tio, ciano y amino; (v) cada R se selecciona, independientemente, del grupo que consiste de hidrogeno, alquilo, alquilo substituido y arilo; (vi) n es un entero de 1 a aproximadamente 5, en donde por lo menos un carbono en (C)n tiene un alquilo o hidroxi diferente, como substituyente y (C)n adyacente a Z tiene uno diferente a amino, SH, CN o hidroxi como R; (vii) Z se selecciona del grupo que consiste de O, NR, S, SO, SO2, PO2RR y POR; (viii) en donde cualquier carbono, cuando esté substituido, teniendo como substituyente uno seleccionado del grupo que consiste de hidroxi, amino, ciano y tiol, tiene el otro substituyente seleccionado del grupo que consiste de hidrogeno, alquilo y arilo, si este substituyente seleccionado del grupo que consiste de hidrogeno, alquilo y arilo, si este substituyente es R o R; y sales farmacéuticamente aceptables de esto compuestos, esteroisomeros y enantiomeros de los mismos, libres de o mezclados con otros enantiomeros o esteroisomeros; y tales compuestos en las composiciones con un vehículo farmacéuticamente aceptables de los mismos comprendiendo una cantidad segura y efectiva de un compuesto activo aclarador de la piel.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US20657394A | 1994-03-04 | 1994-03-04 | |
US08/390,152 US6068834A (en) | 1994-03-04 | 1995-02-24 | Skin lightening compositions |
PCT/US1995/002809 WO1995023780A2 (en) | 1994-03-04 | 1995-03-01 | Skin lightening compositions |
Publications (1)
Publication Number | Publication Date |
---|---|
MX9603879A true MX9603879A (es) | 1997-09-30 |
Family
ID=26901479
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX9603879A MX9603879A (es) | 1994-03-04 | 1995-03-01 | Composiciones aclaradoras de la piel. |
Country Status (13)
Country | Link |
---|---|
US (2) | US6068834A (es) |
EP (1) | EP0748307B1 (es) |
JP (1) | JP3124460B2 (es) |
KR (1) | KR970701685A (es) |
CN (1) | CN1112343C (es) |
AT (1) | ATE210623T1 (es) |
AU (1) | AU701828B2 (es) |
CA (1) | CA2184478A1 (es) |
CZ (1) | CZ257496A3 (es) |
DE (1) | DE69524577T2 (es) |
ES (1) | ES2164763T3 (es) |
MX (1) | MX9603879A (es) |
WO (1) | WO1995023780A2 (es) |
Families Citing this family (89)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU715783B2 (en) * | 1994-03-04 | 2000-02-10 | Procter & Gamble Company, The | Process for making monoacetals of hydroquinone |
US6068834A (en) * | 1994-03-04 | 2000-05-30 | The Procter & Gamble Company | Skin lightening compositions |
US5932196A (en) * | 1994-11-04 | 1999-08-03 | The Procter & Gamble Company | Buffered emulsion compositions containing actives subject to acid or base hydrolysis |
ATE217519T1 (de) * | 1996-07-02 | 2002-06-15 | Procter & Gamble | Hautaufhellungszusammensetzung |
DE69622599T2 (de) * | 1996-08-21 | 2003-03-27 | Childrens Hosp Medical Center | Hautaufhellungszusammensetzungen |
US6497860B1 (en) * | 1996-11-04 | 2002-12-24 | Children's Hospital Medical Center | Skin lightening compositions |
JPH11269066A (ja) * | 1998-03-20 | 1999-10-05 | Kao Corp | 経口用美白剤及び美白用食品 |
US6521267B1 (en) * | 1998-06-08 | 2003-02-18 | Fytokem Prtoducts, Inc. | Tyrosinase inhibitors from plants |
KR100320166B1 (ko) * | 1999-02-19 | 2002-01-18 | 데이비드 엠 모이어 | 피부 미백 조성물 |
US20030072724A1 (en) * | 1999-12-16 | 2003-04-17 | Maibach Howard I. | Topical pharmaceutical composition to treat hyperpigmentation of the skin |
US6417226B1 (en) | 2000-12-12 | 2002-07-09 | Nicholas V. Perricone | Skin whiteners containing hydroxytetronic acid |
US20020182237A1 (en) | 2001-03-22 | 2002-12-05 | The Procter & Gamble Company | Skin care compositions containing a sugar amine |
US6929939B2 (en) | 2001-03-23 | 2005-08-16 | Genencor International, Inc. | Proteins producing an altered immunogenic response and methods of making and using the same |
WO2002087530A1 (en) * | 2001-04-27 | 2002-11-07 | The General Hospital Corporation | Tyrosinase assay |
US7189759B2 (en) | 2001-05-23 | 2007-03-13 | Medicis Pharmaceutical Corporation | Compositions for the treatment of pigmentation disorders and methods for their manufacture |
US7235249B2 (en) | 2002-03-28 | 2007-06-26 | The Procter & Gamble Company | Methods for regulating the condition of mammalian keratinous tissue via topical application of vitamin B6 compositions |
DE60314887T2 (de) * | 2002-09-05 | 2008-03-13 | Galderma Research & Development | Zusammensetzung zur depigmentierung der haut, die adapalen und mindestens ein depigmentierungsmittel enthält |
US20040131648A1 (en) * | 2002-10-24 | 2004-07-08 | The Procter & Gamble Company | Nuclear hormone receptor compounds, products and methods employing same |
DE10258007B4 (de) | 2002-12-12 | 2006-02-09 | Sanofi-Aventis Deutschland Gmbh | Aromatische Fluorglycosidderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zur Herstellung dieser Arzneimittel |
US7098189B2 (en) | 2002-12-16 | 2006-08-29 | Kimberly-Clark Worldwide, Inc. | Wound and skin care compositions |
US20050003024A1 (en) * | 2003-03-04 | 2005-01-06 | The Procter & Gamble Company | Regulation of mammalian hair growth |
US20040175347A1 (en) * | 2003-03-04 | 2004-09-09 | The Procter & Gamble Company | Regulation of mammalian keratinous tissue using hexamidine compositions |
WO2004105718A1 (en) * | 2003-06-03 | 2004-12-09 | Unilever Plc | Skin lightening composition comprising an extract of plants from the families of symplocos or rubia |
EP1686957B1 (en) | 2003-11-17 | 2012-03-07 | Sederma | Compositions containing mixtures of tetrapeptides and tripeptides |
CA2548123C (en) | 2003-12-15 | 2012-05-22 | Kuraray Co., Ltd. | External preparation for skin |
WO2005058314A2 (en) | 2003-12-18 | 2005-06-30 | Unilever Plc | Methods for reducing the effects of stress on skin condition |
US20070160550A1 (en) * | 2004-01-24 | 2007-07-12 | Charles Nee Newsham Rebecca L | Skin lightening compositions |
JP2007530607A (ja) * | 2004-03-30 | 2007-11-01 | ユニリーバー・ナームローゼ・ベンノートシヤープ | ビタミンおよびフラボノイドを含むスキンライトニング組成物 |
US7485666B2 (en) | 2004-06-17 | 2009-02-03 | Kimberly-Clark Worldwide, Inc. | Vaginal health products |
ES2747926T3 (es) | 2004-09-27 | 2020-03-12 | Special Water Patents B V | Métodos y composiciones para el tratamiento de agua |
US7453351B2 (en) * | 2004-10-12 | 2008-11-18 | The Chamberlain Group, Inc. | Delay-based access control apparatus and method |
FR2880802B1 (fr) * | 2005-01-14 | 2008-12-19 | Sederma Soc Par Actions Simpli | Composition cosmetique ou dermopharmaceutique contenant un extrait d'euglene |
US8147853B2 (en) * | 2005-02-15 | 2012-04-03 | The Procter & Gamble Company | Personal care compositions containing hydrophobically modified non-platelet particles |
US20060188559A1 (en) * | 2005-02-18 | 2006-08-24 | E. T. Browne Drug Co. | Topical cosmetic compositions comprising alpha arbutin |
FR2885522B1 (fr) * | 2005-05-13 | 2020-01-10 | Sederma | Composition cosmetique ou dermopharmaceutique contenant de la teprenone |
US20070025937A1 (en) * | 2005-07-29 | 2007-02-01 | L'oreal S.A. | Cosmetic compositions containing hydroquinone |
US20070025939A1 (en) * | 2005-07-29 | 2007-02-01 | L'oreal S.A. | cosmetic compositions containing hydroquinone and various sunscreen agents |
FR2890310B1 (fr) * | 2005-09-06 | 2009-04-03 | Sederma Soc Par Actions Simpli | Utilisation des protoberberines comme agents regulant l'activite de l'unite pilosebacee |
US7485609B2 (en) | 2005-09-29 | 2009-02-03 | Kimberly-Clark Worldwide, Inc. | Encapsulated liquid cleanser |
US7614812B2 (en) | 2005-09-29 | 2009-11-10 | Kimberly-Clark Worldwide, Inc. | Wiper with encapsulated agent |
ES2661728T3 (es) * | 2005-10-03 | 2018-04-03 | Pinksky, Mark A. | Composiciones y métodos para el cuidado mejorado de la piel |
US20070202061A1 (en) * | 2005-10-31 | 2007-08-30 | Naturalnano, Inc. | Cosmetic skincare applications employing mineral-derived tubules for controlled release |
US20070128137A1 (en) * | 2005-12-02 | 2007-06-07 | Naohisa Yoshimi | Water in oil emulsion compositions containing siloxane elastomers |
US8404648B2 (en) * | 2006-02-16 | 2013-03-26 | Sederma | Polypeptides KXK and their use |
FR2900573B1 (fr) * | 2006-05-05 | 2014-05-16 | Sederma Sa | Nouvelles compositions cosmetiques renfermant au moins un peptide contenant au moins un cycle aromatique bloque |
US20070274932A1 (en) * | 2006-05-15 | 2007-11-29 | The Procter & Gamble Company | Water in oil emulsion compositions containing sunscreen actives and siloxane elastomers |
WO2007133768A2 (en) * | 2006-05-15 | 2007-11-22 | The Procter & Gamble Company | Method of enhancing penetration of water-soluble actives |
DE102006028862A1 (de) | 2006-06-23 | 2007-12-27 | Merck Patent Gmbh | 3-Amino-imidazo[1,2-a]pyridinderivate |
FR2904549B1 (fr) * | 2006-08-03 | 2012-12-14 | Sederma Sa | Composition comprenant de la sarsasapogenine |
US20080038360A1 (en) * | 2006-08-11 | 2008-02-14 | Joseph Michael Zukowski | Personal care composition |
US20080070982A1 (en) * | 2006-09-15 | 2008-03-20 | Graham Timmins | System and methods of melanoma prevention |
CN100475189C (zh) | 2006-10-17 | 2009-04-08 | 王海龙 | 一种化妆品组合物及其制备方法和应用 |
DE102006058236A1 (de) | 2006-12-11 | 2008-06-12 | Merck Patent Gmbh | Indolizinderivate |
MX2009007048A (es) * | 2006-12-26 | 2009-07-10 | Romano Dev Inc | Composicion aclaradora cutanea para piel hiperpigmentada. |
EP1952845A1 (en) | 2007-01-26 | 2008-08-06 | DSMIP Assets B.V. | Use of an astaxathin derivative for cosmetic purposes |
DE102007008420A1 (de) | 2007-02-21 | 2008-08-28 | Merck Patent Gmbh | Benzimidazolderivate |
US20090011035A1 (en) * | 2007-07-03 | 2009-01-08 | Joseph Michael Zukowski | Personal care composition |
DE102007048716A1 (de) | 2007-10-11 | 2009-04-23 | Merck Patent Gmbh | Imidazo[1,2-a]pyrimidinderivate |
FR2924601A1 (fr) * | 2007-12-07 | 2009-06-12 | Oreal | Composes diphosphate d'hydroquinone et leur utilisation pour depigmenter la peau. |
ES2710498T3 (es) | 2007-12-26 | 2019-04-25 | Mark A Pinsky | Formulaciones de colágeno para la mejora del cuidado de la piel |
DE102008017590A1 (de) | 2008-04-07 | 2009-10-08 | Merck Patent Gmbh | Glucopyranosidderivate |
FR2939136B1 (fr) * | 2008-12-02 | 2010-12-03 | Galderma Res & Dev | Nouveaux composes 4-(heterocycloalkyl)-benzene-1,3-diol comme inhibiteurs de la tyrosinase, leur procede de preparation et leur utilisation en medecine humaine ainsi qu'en cosmetique |
FR2939799B1 (fr) | 2008-12-11 | 2011-03-11 | Sederma Sa | Composition cosmetique comprenant des oligoglucuronanes acetyles. |
WO2010082177A2 (en) | 2009-01-16 | 2010-07-22 | Sederma | New compounds, in particular peptides, compositions comprising them and cosmetic and dermopharmaceutical uses |
FR2941231B1 (fr) | 2009-01-16 | 2016-04-01 | Sederma Sa | Nouveaux peptides, compositions les comprenant et utilisations cosmetiques et dermo-pharmaceutiques. |
FR2944435B1 (fr) | 2009-04-17 | 2011-05-27 | Sederma Sa | Composition cosmetique comprenant de l'oridonine |
EP2456419B1 (en) | 2009-07-21 | 2016-11-23 | Oradin Pharmaceutical Ltd. | A3 adenosine receptor ligands for modulation of pigmentation |
CA3045407C (en) | 2009-07-29 | 2024-03-12 | Elise A. Olsen | Compositions and methods for inhibiting hair growth |
CA2800537C (en) | 2010-06-11 | 2016-02-09 | The Procter & Gamble Company | Compositions for treating skin |
KR101395146B1 (ko) * | 2011-02-09 | 2014-05-16 | 부산대학교 산학협력단 | 피부미백, 항산화 및 ppar 활성을 갖는 신규 화합물 및 이의 의학적 용도 |
US20130052244A1 (en) | 2011-08-30 | 2013-02-28 | Mark Weinreb | Stem Cell Compositions and Methods |
WO2013091894A2 (en) | 2011-12-21 | 2013-06-27 | Flavin Dana | Topical compositions |
CN104271124A (zh) * | 2012-01-05 | 2015-01-07 | 梅兹北美公司 | 手性化合物、组合物、产品和其使用方法 |
MX2014008225A (es) * | 2012-01-05 | 2014-10-06 | Merz North America Inc | Composiciones para aclarar la piel. |
US8895041B2 (en) | 2012-03-23 | 2014-11-25 | The Procter & Gamble Company | Compositions for delivering perfume to the skin |
TW201437211A (zh) * | 2013-03-01 | 2014-10-01 | Bayer Pharma AG | 經取代咪唑并嗒□ |
US9856290B2 (en) | 2013-12-10 | 2018-01-02 | Sussex Research Laboratories Inc. | Glycopeptide compositions and uses thereof |
US20160000682A1 (en) | 2014-07-02 | 2016-01-07 | Geoffrey Brooks Consultants Llc | Peptide-Based Compositions and Methods of Use |
US11207248B2 (en) | 2014-11-10 | 2021-12-28 | The Procter And Gamble Company | Personal care compositions with two benefit phases |
CN107148263B (zh) | 2014-11-10 | 2021-07-06 | 宝洁公司 | 个人护理组合物 |
WO2016077327A1 (en) | 2014-11-10 | 2016-05-19 | The Procter & Gamble Company | Personal care compositions with two benefit phases |
US10966916B2 (en) | 2014-11-10 | 2021-04-06 | The Procter And Gamble Company | Personal care compositions |
WO2016139501A1 (en) * | 2015-03-04 | 2016-09-09 | Tfchem | Gem difluorocompounds as depigmenting or lightening agents |
WO2018037254A1 (en) * | 2016-08-24 | 2018-03-01 | Tfchem | Difluorinated compounds as depigmenting or lightening agents |
WO2019079405A1 (en) | 2017-10-20 | 2019-04-25 | The Procter & Gamble Company | AEROSOL FOAMING CLEANSER FOR THE SKIN |
EP3697375B1 (en) | 2017-10-20 | 2021-12-01 | The Procter & Gamble Company | Aerosol foam skin cleanser |
WO2019113035A1 (en) | 2017-12-08 | 2019-06-13 | The Procter & Gamble Company | Methods of screening for mild skin cleanser |
EP3813786A4 (en) | 2018-06-27 | 2022-06-29 | Colabs International Corporation | Compositions comprising silicon dioxide-based particles including one or more agents |
WO2020112486A1 (en) | 2018-11-29 | 2020-06-04 | The Procter & Gamble Company | Methods for screening personal care products |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3856934A (en) | 1970-06-24 | 1974-12-24 | A Kligman | Skin depigmentation |
AR205618A1 (es) | 1973-01-17 | 1976-05-21 | Ciba Geigy Ag | Procedimiento para la elaboracion de derivados del 1-(4-alquiltio-alcoxi)-fenoxi - 2 - hidroxi-3-alquilaminopropano |
JPS55127334A (en) | 1979-03-26 | 1980-10-02 | Ihara Chem Ind Co Ltd | Preparation of substituted phenols |
HU190371B (en) * | 1980-12-18 | 1986-08-28 | The Wellcome Foundation Ltd,Gb | Process for producing ether-type compounds and pharmaceutical compositions containing them as active agents |
US4328361A (en) | 1981-01-16 | 1982-05-04 | The Upjohn Company | Novel process |
JPS57145803A (en) | 1981-03-05 | 1982-09-09 | Sunstar Inc | External decoloring agent for skin |
US4545982A (en) | 1982-03-17 | 1985-10-08 | Yakurigaku Chuo Kenkyusho | Pyranone compounds and skin-lightening cosmetic preparations or local demelanizing agents containing the same |
US4466955A (en) | 1982-06-09 | 1984-08-21 | Germaine Monteil Cosmetiques Corporation | Skin bleaching stick containing hydroquinone |
JPH0832621B2 (ja) * | 1985-02-28 | 1996-03-29 | 株式会社資生堂 | 皮膚外用剤 |
JPS6056912A (ja) | 1983-09-07 | 1985-04-02 | Shiseido Co Ltd | 皮膚外用剤 |
JPS6289608A (ja) * | 1985-10-16 | 1987-04-24 | Shiseido Co Ltd | 皮膚外用剤 |
JPS638314A (ja) * | 1986-06-28 | 1988-01-14 | Sansho Seiyaku Kk | 外用剤 |
US4983382A (en) | 1987-01-27 | 1991-01-08 | Avon Products, Inc. | Cosmetic preparation incorporating stabilized ascorbic acid |
JPS6479103A (en) | 1987-06-09 | 1989-03-24 | Lion Corp | External preparation |
FR2616328B1 (fr) | 1987-06-12 | 1990-03-02 | Moet Hennessy Rech | Composition a base de phases lamellaires lipidiques hydratees ou de liposomes contenant un extrait de murier, ou au moins une flavone, en particulier une kuwanone et composition pharmaceutique, notamment dermatologique, a activite depigmentante, ou anti-inflammatoire, ou cosmetique, l'incorporant |
EP0383319A3 (en) | 1989-02-17 | 1991-07-31 | Takeda Chemical Industries, Ltd. | Imidazopyridines, their production and use |
US5126125A (en) | 1989-10-06 | 1992-06-30 | Yale University | Decreasing the melanin content in mammalian skin and hair using 5,6-dihydroxindole derivatives |
GB9109965D0 (en) | 1991-05-07 | 1991-07-03 | Unilever Plc | Cosmetic composition |
FR2679140B1 (fr) * | 1991-07-19 | 1993-10-15 | Oreal | Composition cosmetique ou dermatologique depigmentante contenant des derives d'arbutoside. |
JPH06192062A (ja) * | 1992-12-24 | 1994-07-12 | Shiseido Co Ltd | 皮膚外用剤 |
US6068834A (en) * | 1994-03-04 | 2000-05-30 | The Procter & Gamble Company | Skin lightening compositions |
-
1995
- 1995-02-24 US US08/390,152 patent/US6068834A/en not_active Expired - Lifetime
- 1995-03-01 KR KR1019960704858A patent/KR970701685A/ko not_active Application Discontinuation
- 1995-03-01 CN CN95192636A patent/CN1112343C/zh not_active Expired - Fee Related
- 1995-03-01 MX MX9603879A patent/MX9603879A/es unknown
- 1995-03-01 CA CA002184478A patent/CA2184478A1/en not_active Abandoned
- 1995-03-01 WO PCT/US1995/002809 patent/WO1995023780A2/en active IP Right Grant
- 1995-03-01 AU AU19399/95A patent/AU701828B2/en not_active Ceased
- 1995-03-01 AT AT95912061T patent/ATE210623T1/de active
- 1995-03-01 ES ES95912061T patent/ES2164763T3/es not_active Expired - Lifetime
- 1995-03-01 DE DE69524577T patent/DE69524577T2/de not_active Expired - Lifetime
- 1995-03-01 EP EP95912061A patent/EP0748307B1/en not_active Expired - Lifetime
- 1995-03-01 CZ CZ962574A patent/CZ257496A3/cs unknown
- 1995-03-06 JP JP07072331A patent/JP3124460B2/ja not_active Expired - Fee Related
-
1998
- 1998-08-13 US US09/133,861 patent/US6537527B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CN1146196A (zh) | 1997-03-26 |
DE69524577D1 (de) | 2002-01-24 |
CA2184478A1 (en) | 1995-09-08 |
WO1995023780A2 (en) | 1995-09-08 |
EP0748307B1 (en) | 2001-12-12 |
EP0748307A1 (en) | 1996-12-18 |
ATE210623T1 (de) | 2001-12-15 |
KR970701685A (ko) | 1997-04-12 |
ES2164763T3 (es) | 2002-03-01 |
CZ257496A3 (en) | 1997-01-15 |
US6068834A (en) | 2000-05-30 |
WO1995023780A3 (en) | 1995-09-28 |
DE69524577T2 (de) | 2002-10-31 |
JPH0848620A (ja) | 1996-02-20 |
AU1939995A (en) | 1995-09-18 |
US6537527B1 (en) | 2003-03-25 |
CN1112343C (zh) | 2003-06-25 |
AU701828B2 (en) | 1999-02-04 |
JP3124460B2 (ja) | 2001-01-15 |
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