MX9302927A - Nuevos peptidos, la preparacion y utilizacion de los mimos. - Google Patents

Nuevos peptidos, la preparacion y utilizacion de los mimos.

Info

Publication number
MX9302927A
MX9302927A MX9302927A MX9302927A MX9302927A MX 9302927 A MX9302927 A MX 9302927A MX 9302927 A MX9302927 A MX 9302927A MX 9302927 A MX9302927 A MX 9302927A MX 9302927 A MX9302927 A MX 9302927A
Authority
MX
Mexico
Prior art keywords
preparation
mimos
new peptides
new
peptides
Prior art date
Application number
MX9302927A
Other languages
English (en)
Inventor
Andreas Haupt Franz Romerdahl
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of MX9302927A publication Critical patent/MX9302927A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/101—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

Nuevos péptidos de la fórmula (I); en la que R1, R2, A, B, D, EW, F, G, K, X, t, u, v y w tienen los significados que se indican en la descripción, describiendose así mismo la preparación de los mismos. Las nuevas sustancias tienen un efecto antineplástico.
MX9302927A 1992-05-20 1993-05-19 Nuevos peptidos, la preparacion y utilizacion de los mimos. MX9302927A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US88578892A 1992-05-20 1992-05-20
US98569692A 1992-11-25 1992-11-25

Publications (1)

Publication Number Publication Date
MX9302927A true MX9302927A (es) 1993-11-01

Family

ID=27128772

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9302927A MX9302927A (es) 1992-05-20 1993-05-19 Nuevos peptidos, la preparacion y utilizacion de los mimos.

Country Status (21)

Country Link
EP (1) EP0642530B1 (es)
JP (2) JP3523253B2 (es)
KR (1) KR100286242B1 (es)
CN (1) CN1065874C (es)
AT (1) ATE169637T1 (es)
AU (1) AU669710B2 (es)
CA (1) CA2136339C (es)
CZ (1) CZ292612B6 (es)
DE (1) DE69320339T2 (es)
DK (1) DK0642530T3 (es)
ES (1) ES2118955T3 (es)
FI (1) FI120692B (es)
HU (2) HUT71398A (es)
IL (1) IL105651A (es)
MX (1) MX9302927A (es)
NO (1) NO310465B1 (es)
NZ (1) NZ252147A (es)
RU (1) RU2116312C1 (es)
SI (1) SI9300267A (es)
UA (1) UA45304C2 (es)
WO (1) WO1993023424A1 (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5831002A (en) * 1992-05-20 1998-11-03 Basf Aktiengesellschaft Antitumor peptides
DE4415997A1 (de) * 1994-05-06 1995-11-09 Basf Ag Neuer peptidischer Wirkstoff und dessen Herstellung
DE4415998A1 (de) * 1994-05-06 1995-11-09 Basf Ag Neue Tetrapeptide, ihre Herstellung Verwendung
DE19527574A1 (de) * 1995-07-28 1997-01-30 Basf Ag Verfahren zur Herstellung vona-(N,N-Dialkyl)-aminocaarbonsäureamiden
DE19527575A1 (de) * 1995-07-28 1997-01-30 Basf Ag Verfahren zur Herstellung von peptidischer Wirkstoffe
US5807984A (en) * 1995-11-09 1998-09-15 Basf Aktienegesellschaft Oligopeptides, the preparation and use thereof
US20010009901A1 (en) 1996-12-11 2001-07-26 Basf Aktiengesellschaft Germany Antineoplastic peptides
AU775090B2 (en) * 1995-12-15 2004-07-15 Abbvie Deutschland Gmbh & Co Kg Antineoplastic peptides
TW474946B (en) * 1995-12-15 2002-02-01 Basf Ag Novel compounds, the preparation and use thereof
US5741892A (en) * 1996-07-30 1998-04-21 Basf Aktiengesellschaft Pentapeptides as antitumor agents
US5939527A (en) * 1996-07-30 1999-08-17 Basf Aktiengesellschaft Tetrapeptides as antitumor agents
US5965537A (en) * 1997-03-10 1999-10-12 Basf Aktiengesellschaft Dolastatin 15 derivatives with carbonyl and heterocyclic functionalities at the C-terminus
US6143721A (en) * 1997-07-18 2000-11-07 Basf Aktiengesellschaft Dolastatin 15 derivatives
WO1999015130A2 (en) * 1997-09-24 1999-04-01 ARIZONA BOARD OF REGENTS, actingon behalf of ARIZ ONA STATE UNIVERSITY Synthetic antineoplastic agents derived from dolastatin 15 and methods of making same
US6686445B1 (en) 1997-09-24 2004-02-03 Arizona Board Of Regents, Acting For And On Behalf Of Arizona State University Synthetic antineoplastic agents derived from dolastatin 15 and methods of making same
US5985837A (en) * 1998-07-08 1999-11-16 Basf Aktiengesellschaft Dolastatin 15 derivatives
ATE415413T1 (de) * 2002-07-15 2008-12-15 Univ Princeton Iap-bindende verbindungen
US7425644B2 (en) 2003-11-24 2008-09-16 TEVA Gyógyszergyár Zártkörűen Működő Részvénytársaság Method of purifying pravastatin
WO2023033129A1 (ja) 2021-09-03 2023-03-09 東レ株式会社 癌の治療及び／又は予防用医薬組成物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816444A (en) * 1987-07-10 1989-03-28 Arizona Board Of Regents, Arizona State University Cell growth inhibitory substance
US4879278A (en) * 1989-05-16 1989-11-07 Arizona Board Of Regents Isolation and structural elucidation of the cytostatic linear depsipeptide dolastatin 15
KR0185440B1 (ko) * 1991-08-09 1999-04-01 야마구찌 다까시 신규의 테트라 펩티트 유도체

Also Published As

Publication number Publication date
AU4066293A (en) 1993-12-13
FI945416L (fi) 1994-11-17
CZ292612B6 (cs) 2003-11-12
IL105651A0 (en) 1993-09-22
CA2136339C (en) 2008-02-05
UA45304C2 (uk) 2002-04-15
DE69320339T2 (de) 1998-12-17
NO944419D0 (no) 1994-11-18
JP3523253B2 (ja) 2004-04-26
ATE169637T1 (de) 1998-08-15
ES2118955T3 (es) 1998-10-01
AU669710B2 (en) 1996-06-20
WO1993023424A1 (en) 1993-11-25
SI9300267A (sl) 1993-12-31
RU94046434A (ru) 1996-10-27
DK0642530T3 (da) 1998-10-26
KR100286242B1 (ko) 2001-04-16
IL105651A (en) 1998-07-15
RU2116312C1 (ru) 1998-07-27
CZ284394A3 (en) 1995-05-17
NO310465B1 (no) 2001-07-09
JPH07506580A (ja) 1995-07-20
NZ252147A (en) 1996-10-28
CN1085563A (zh) 1994-04-20
CN1065874C (zh) 2001-05-16
DE69320339D1 (de) 1998-09-17
NO944419L (no) 1995-01-09
FI945416A0 (fi) 1994-11-17
EP0642530B1 (en) 1998-08-12
FI120692B (fi) 2010-01-29
JP2004149538A (ja) 2004-05-27
CA2136339A1 (en) 1993-11-25
HUT71398A (en) 1995-11-28
HU211745A9 (en) 1995-12-28
EP0642530A1 (en) 1995-03-15

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