MX390699B - Composiciones y metodos para inhibicion de genes para apolipoproteina c-iii (apoc3). - Google Patents

Composiciones y metodos para inhibicion de genes para apolipoproteina c-iii (apoc3).

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Publication number
MX390699B
MX390699B MX2017000251A MX2017000251A MX390699B MX 390699 B MX390699 B MX 390699B MX 2017000251 A MX2017000251 A MX 2017000251A MX 2017000251 A MX2017000251 A MX 2017000251A MX 390699 B MX390699 B MX 390699B
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MX
Mexico
Prior art keywords
apoc3
methods
apolipoprotein
genes
inhibition
Prior art date
Application number
MX2017000251A
Other languages
English (en)
Inventor
Brian Bettencourt
Kallanthottathil Rajeev
Kevin Fitzgerald
Klaus Charisse
Martin Maier
Muthiah Manoharan
Satya Kuchimanchi
Stuart Milstein
Tuyen Nguyen
Original Assignee
Alnylam Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alnylam Pharmaceuticals Inc filed Critical Alnylam Pharmaceuticals Inc
Publication of MX390699B publication Critical patent/MX390699B/es

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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
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Abstract

La presente invención se refiere a un ácido ribonucleico de doble hebra (ARNds) dirigido a un gen para APOC3, y métodos de uso del ARNds para inhibir la expresión de APOC3.
MX2017000251A 2011-06-21 2012-06-21 Composiciones y metodos para inhibicion de genes para apolipoproteina c-iii (apoc3). MX390699B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161499620P 2011-06-21 2011-06-21
PCT/US2012/043642 WO2012177947A2 (en) 2011-06-21 2012-06-21 Compositions and methods for inhibition of expression of apolipoprotein c-iii (apoc3) genes

Publications (1)

Publication Number Publication Date
MX390699B true MX390699B (es) 2025-03-21

Family

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Family Applications (3)

Application Number Title Priority Date Filing Date
MX2013014378A MX344807B (es) 2011-06-21 2012-06-21 Composiciones y metodos para inhibicion de genes para alipoproteina c-iii (apoc3).
MX2017000251A MX390699B (es) 2011-06-21 2012-06-21 Composiciones y metodos para inhibicion de genes para apolipoproteina c-iii (apoc3).
MX2021015290A MX2021015290A (es) 2011-06-21 2013-12-06 Composiciones y metodos para inhibicion de genes para apolipoproteina c-iii (apoc3).

Family Applications Before (1)

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MX2013014378A MX344807B (es) 2011-06-21 2012-06-21 Composiciones y metodos para inhibicion de genes para alipoproteina c-iii (apoc3).

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MX2021015290A MX2021015290A (es) 2011-06-21 2013-12-06 Composiciones y metodos para inhibicion de genes para apolipoproteina c-iii (apoc3).

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US (6) US9315813B2 (es)
EP (2) EP2723756B1 (es)
JP (6) JP6236385B2 (es)
KR (5) KR20260004562A (es)
CN (3) CN112111492A (es)
AU (7) AU2012272860A1 (es)
BR (1) BR112013032645A2 (es)
CA (2) CA2839711C (es)
MX (3) MX344807B (es)
RU (1) RU2631805C2 (es)
WO (1) WO2012177947A2 (es)

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