MX389979B - Edulcorantes no calóricos y métodos para sintetizar. - Google Patents
Edulcorantes no calóricos y métodos para sintetizar.Info
- Publication number
- MX389979B MX389979B MX2017004248A MX2017004248A MX389979B MX 389979 B MX389979 B MX 389979B MX 2017004248 A MX2017004248 A MX 2017004248A MX 2017004248 A MX2017004248 A MX 2017004248A MX 389979 B MX389979 B MX 389979B
- Authority
- MX
- Mexico
- Prior art keywords
- rebaudioside
- methods
- reb
- sweeteners
- synthesizing
- Prior art date
Links
- 230000002194 synthesizing effect Effects 0.000 title abstract 2
- 235000003599 food sweetener Nutrition 0.000 title 1
- 239000003765 sweetening agent Substances 0.000 title 1
- 229930188195 rebaudioside Natural products 0.000 abstract 5
- 235000013615 non-nutritive sweetener Nutrition 0.000 abstract 2
- 239000004383 Steviol glycoside Substances 0.000 abstract 1
- 235000021096 natural sweeteners Nutrition 0.000 abstract 1
- GSGVXNMGMKBGQU-PHESRWQRSA-N rebaudioside M Chemical compound C[C@@]12CCC[C@](C)([C@H]1CC[C@@]13CC(=C)[C@@](C1)(CC[C@@H]23)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H]1O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)C(=O)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H]1O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O GSGVXNMGMKBGQU-PHESRWQRSA-N 0.000 abstract 1
- 229930182488 steviol glycoside Natural products 0.000 abstract 1
- 235000019411 steviol glycoside Nutrition 0.000 abstract 1
- 150000008144 steviol glycosides Chemical class 0.000 abstract 1
- 235000019202 steviosides Nutrition 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
- A23L2/52—Adding ingredients
- A23L2/60—Sweeteners
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/30—Artificial sweetening agents
- A23L27/33—Artificial sweetening agents containing sugars or derivatives
- A23L27/36—Terpene glycosides
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/256—Polyterpene radicals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1051—Hexosyltransferases (2.4.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1051—Hexosyltransferases (2.4.1)
- C12N9/1062—Sucrose synthase (2.4.1.13)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/18—Preparation of compounds containing saccharide radicals produced by the action of a glycosyl transferase, e.g. alpha-, beta- or gamma-cyclodextrins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/56—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound to a condensed ring system having three or more carbocyclic rings, e.g. daunomycin, adriamycin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y204/00—Glycosyltransferases (2.4)
- C12Y204/01—Hexosyltransferases (2.4.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y204/00—Glycosyltransferases (2.4)
- C12Y204/01—Hexosyltransferases (2.4.1)
- C12Y204/01013—Sucrose synthase (2.4.1.13)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y204/00—Glycosyltransferases (2.4)
- C12Y204/01—Hexosyltransferases (2.4.1)
- C12Y204/01017—Glucuronosyltransferase (2.4.1.17)
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Nutrition Science (AREA)
- Polymers & Plastics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Mycology (AREA)
- Seasonings (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Non-Alcoholic Beverages (AREA)
- Enzymes And Modification Thereof (AREA)
- Saccharide Compounds (AREA)
- Cosmetics (AREA)
- Fodder In General (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Tea And Coffee (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462059498P | 2014-10-03 | 2014-10-03 | |
| US201462098929P | 2014-12-31 | 2014-12-31 | |
| PCT/US2015/053777 WO2016054540A1 (en) | 2014-10-03 | 2015-10-02 | Non-caloric sweeteners and methods for synthesizing |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2017004248A MX2017004248A (es) | 2017-05-19 |
| MX389979B true MX389979B (es) | 2025-03-20 |
Family
ID=55631622
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2017004248A MX389979B (es) | 2014-10-03 | 2015-10-02 | Edulcorantes no calóricos y métodos para sintetizar. |
| MX2017004247A MX368414B (es) | 2014-10-03 | 2015-10-02 | Edulcorantes no caloricos y metodos para sintetizar. |
| MX2017004246A MX378831B (es) | 2014-10-03 | 2015-10-02 | Edulcorantes no caloricos y metodos para sintetizar |
| MX2017004245A MX367090B (es) | 2014-10-03 | 2015-10-02 | Edulcorantes no caloricos y metodos para sintetizar. |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2017004247A MX368414B (es) | 2014-10-03 | 2015-10-02 | Edulcorantes no caloricos y metodos para sintetizar. |
| MX2017004246A MX378831B (es) | 2014-10-03 | 2015-10-02 | Edulcorantes no caloricos y metodos para sintetizar |
| MX2017004245A MX367090B (es) | 2014-10-03 | 2015-10-02 | Edulcorantes no caloricos y metodos para sintetizar. |
Country Status (14)
| Country | Link |
|---|---|
| US (22) | US9850270B2 (https=) |
| EP (4) | EP3201212B1 (https=) |
| JP (4) | JP6774945B2 (https=) |
| KR (4) | KR102526446B1 (https=) |
| CN (7) | CN106714578B (https=) |
| AU (4) | AU2015327940B2 (https=) |
| BR (3) | BR112017006163B1 (https=) |
| CA (4) | CA2958105C (https=) |
| DK (3) | DK3201351T3 (https=) |
| ES (3) | ES2869823T3 (https=) |
| HU (2) | HUE045992T2 (https=) |
| MX (4) | MX389979B (https=) |
| MY (4) | MY190567A (https=) |
| WO (4) | WO2016054534A1 (https=) |
Families Citing this family (56)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY199452A (en) | 2013-02-06 | 2023-10-30 | Evolva Sa | Methods for improved production of rebaudioside d and rebaudioside m |
| US9522929B2 (en) | 2014-05-05 | 2016-12-20 | Conagen Inc. | Non-caloric sweetener |
| US10264811B2 (en) | 2014-05-19 | 2019-04-23 | Epc Natural Products Co., Ltd. | Stevia sweetener with improved solubility |
| BR112017006163B1 (pt) | 2014-10-03 | 2022-04-05 | Conagen Inc | Produto de consumo oral e método para adoçar o mesmo |
| CN107249356B (zh) | 2014-12-17 | 2021-08-06 | 嘉吉公司 | 用于口服摄入或使用的甜菊醇糖苷化合物、组合物以及用于增强甜菊醇糖苷溶解度的方法 |
| EP3250686A1 (en) | 2015-01-30 | 2017-12-06 | Evolva SA | Production of steviol glycosides in recombinant hosts |
| CN107666834B (zh) | 2015-04-03 | 2021-08-24 | 帝斯曼知识产权资产管理有限公司 | 甜菊醇糖苷 |
| KR102569053B1 (ko) | 2015-04-14 | 2023-08-21 | 코나겐 인크. | 조작된 전체 세포 촉매를 사용한 비칼로리 감미료의 제조 |
| US20190203244A1 (en) * | 2015-08-20 | 2019-07-04 | Pepsico, Inc. | Preparation of rebaudioside m in a single reaction vessel |
| US10982249B2 (en) | 2016-04-13 | 2021-04-20 | Evolva Sa | Production of steviol glycosides in recombinant hosts |
| JP2019517801A (ja) | 2016-06-15 | 2019-06-27 | コデクシス， インコーポレイテッド | 操作されたβ−グルコシダーゼおよびグルコシル化方法 |
| WO2017218036A1 (en) * | 2016-06-17 | 2017-12-21 | Cargill, Incorporated | Steviol glycoside compositions for oral ingestion or use |
| PT3497222T (pt) | 2016-08-12 | 2022-02-09 | Amyris Inc | Glicosiltransferase dependente de udp para produção de eficácia elevada de rebaudiosídeos |
| BR112019007504B1 (pt) * | 2016-10-14 | 2023-05-09 | Conagen Inc | Método de preparação de uma composição de glicosídeo de esteviol |
| BR112019008048A2 (pt) | 2016-10-21 | 2019-07-02 | Pepsico Inc | método para preparar rebaudiosídeo n com o uso de método enzimático |
| CN116574775A (zh) * | 2016-10-21 | 2023-08-11 | 百事可乐公司 | 一种酶法制备瑞鲍迪甙j的方法 |
| WO2018093196A1 (ko) * | 2016-11-17 | 2018-05-24 | 서울대학교산학협력단 | 변형 류코노스톡속 균주를 이용한 스테비오사이드 배당체의 합성 방법 및 이에 의하여 제조된 신규한 스테비오사이드 배당체 |
| KR102674902B1 (ko) * | 2016-12-01 | 2024-06-14 | 아비나스 오퍼레이션스, 인코포레이티드 | 에스트로겐 수용체 분해제로서의 테트라히드로나프탈렌 및 테트라히드로이소퀴놀린 유도체 |
| KR102905512B1 (ko) | 2017-02-03 | 2025-12-29 | 테이트 앤드 라일 솔루션스 유에스에이 엘엘씨 | 조작된 글리코실트랜스퍼라제 및 스테비올 글리코시드 글루코실화 방법 |
| CA3061045A1 (en) * | 2017-04-25 | 2018-11-01 | The Coca-Cola Company | Sweetness and taste improvement of steviol glycoside and mogroside sweeteners with dihydrochalcones |
| CN107164435B (zh) * | 2017-05-27 | 2020-03-31 | 中国药科大学 | 一种莱鲍迪苷ka的制备方法 |
| CA3066340A1 (en) | 2017-06-08 | 2018-12-13 | Suntory Holdings Limited | Food or beverage with increased sweetness |
| CN110809408B (zh) | 2017-06-30 | 2024-09-10 | 科纳根公司 | 通过β-葡糖苷酶水解甜菊醇糖苷 |
| CN111868252B (zh) * | 2018-03-12 | 2025-06-03 | 科纳根公司 | 甜菊糖苷莱苞迪苷j和莱苞迪苷n的生物合成生产 |
| EP3813545A4 (en) * | 2018-05-08 | 2023-03-22 | EPC Natural Products Co., Ltd. | STEVIOLGLYCOSIDE COMPOSITIONS WITH IMPROVED TASTE |
| CN109021038B (zh) * | 2018-06-11 | 2021-07-27 | 江西师范大学 | 一种甜菊糖苷的制备方法 |
| IL280302B2 (en) * | 2018-07-30 | 2025-09-01 | Codexis Inc | Engineered glycosyltransferases and methods for glycosylation of steviol glycoside |
| WO2019210607A1 (zh) * | 2018-08-17 | 2019-11-07 | 邦泰生物工程(深圳)有限公司 | 一种稳定型烟酰胺核糖组合物及其制备方法 |
| CN111073923A (zh) * | 2018-10-22 | 2020-04-28 | 山东三元生物科技股份有限公司 | 一种莱鲍迪苷m的酶法制备方法 |
| EP3877519B1 (en) | 2018-11-09 | 2026-03-11 | Ginkgo Bioworks, Inc. | Biosynthesis of mogrosides |
| WO2020116637A1 (ja) * | 2018-12-07 | 2020-06-11 | サントリーホールディングス株式会社 | 糖および甘味料の呈する味質が改善したコーヒー飲料 |
| WO2020116664A1 (en) * | 2018-12-07 | 2020-06-11 | Suntory Holdings Limited | Composition |
| WO2020116665A1 (en) * | 2018-12-07 | 2020-06-11 | Suntory Holdings Limited | Composition |
| WO2020116638A1 (ja) * | 2018-12-07 | 2020-06-11 | サントリーホールディングス株式会社 | 糖および甘味料の呈する味質が改善したコーヒー飲料 |
| WO2020123877A1 (en) * | 2018-12-12 | 2020-06-18 | Conagen Inc. | Biosynthetic production of variant steviol glycosides |
| CN109750072B (zh) * | 2019-01-31 | 2022-04-19 | 南京工业大学 | 一种酶法制备莱鲍迪苷e的方法 |
| EP3799057A1 (en) | 2019-09-25 | 2021-03-31 | Koninklijke Philips N.V. | Prediction tool for patient immune response to a therapy |
| US20240148037A1 (en) * | 2019-10-16 | 2024-05-09 | Sweegen, Inc. | Steviol glycoside formulations for food and beverages |
| CN110846363B (zh) * | 2019-11-11 | 2023-02-17 | 天津大学 | 一锅法生产莱鲍迪苷d的方法 |
| CN110872586B (zh) * | 2019-11-11 | 2024-01-30 | 天津大学 | 固定化葡萄糖基转移酶及制备方法及催化生产莱鲍迪苷d的方法 |
| CN110734944B (zh) * | 2019-11-11 | 2023-02-21 | 中化健康产业发展有限公司 | 一步法合成莱鲍迪苷m的方法 |
| CN110846305B (zh) * | 2019-11-11 | 2023-11-28 | 中化健康产业发展有限公司 | 一种固定化糖基转移酶催化莱鲍迪苷a生成莱鲍迪苷m的方法 |
| EP4117452A4 (en) * | 2020-03-13 | 2024-03-27 | Amyris, Inc. | REBAUDIOSIDE-M SWEETENER COMPOSITIONS |
| JP7781769B2 (ja) * | 2020-04-20 | 2025-12-08 | ザ コカ・コーラ カンパニー | 香味が増強されたシアメノシドｉを含む飲料 |
| WO2022139522A1 (ko) * | 2020-12-23 | 2022-06-30 | 주식회사 삼양사 | 당전이 효소 및 이를 이용한 스테비올 배당체의 제조방법 |
| JP7210626B2 (ja) * | 2021-02-18 | 2023-01-23 | ペプシコ・インク | 酵素的方法を使用してレバウディオサイドｊを調製するための方法 |
| US20250051818A1 (en) * | 2021-12-24 | 2025-02-13 | Samyang Corporation | Production of rebaudioside |
| EP4496482A1 (en) | 2022-03-23 | 2025-01-29 | Sweegen, Inc. | Sweetener comprising rebaudiose m and brazzein |
| CN114921434B (zh) * | 2022-05-27 | 2024-02-20 | 中化健康产业发展有限公司 | 催化Reb A生产Reb M的重组糖基转移酶 |
| DE202022103252U1 (de) | 2022-06-09 | 2022-07-01 | Wal Ankita | Eine natürliche Süßstoffzusammensetzung als Süßungsmittel für Diabetes |
| CN116076694B (zh) * | 2022-10-12 | 2024-06-28 | 四川盈嘉合生科技有限公司 | 一种甜菊糖苷甜味剂及其制备方法 |
| CN117209563B (zh) * | 2023-09-15 | 2025-09-19 | 郑州大学 | 呈味肽及其应用 |
| KR102876472B1 (ko) * | 2023-12-26 | 2025-10-27 | 주식회사 삼양사 | 수크로우스 합성효소 변이체, udp-글루코실트랜스퍼라제 변이체 및 이들의 스테비올 배당체 생산 용도 |
| KR102777875B1 (ko) * | 2024-10-22 | 2025-03-13 | 대한민국 | 신규 페디오코커스 속 균주 및 그의 용도 |
| CN119842657B (zh) * | 2025-03-18 | 2025-05-27 | 青岛奔月生物技术有限公司 | 蔗糖合酶突变体及其应用 |
| CN120813686A (zh) * | 2025-05-07 | 2025-10-17 | 邦泰生物工程(深圳)有限公司 | 一种udp-葡萄糖基转移酶突变体及其制备莱鲍迪苷d的方法 |
Family Cites Families (37)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US17804A (en) * | 1857-07-14 | Improvement in locks | ||
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