MX388939B - Anticuerpo anti-il-1a para usarse en el tratamiento de cáncer metastásico. - Google Patents

Anticuerpo anti-il-1a para usarse en el tratamiento de cáncer metastásico.

Info

Publication number
MX388939B
MX388939B MX2016013346A MX2016013346A MX388939B MX 388939 B MX388939 B MX 388939B MX 2016013346 A MX2016013346 A MX 2016013346A MX 2016013346 A MX2016013346 A MX 2016013346A MX 388939 B MX388939 B MX 388939B
Authority
MX
Mexico
Prior art keywords
treatment
neoplastic diseases
mab
administration
useful
Prior art date
Application number
MX2016013346A
Other languages
English (en)
Inventor
John Simard
Original Assignee
Xbiotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xbiotech Inc filed Critical Xbiotech Inc
Publication of MX388939B publication Critical patent/MX388939B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C07K16/245—IL-1
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/04—Drugs for disorders of the respiratory system for throat disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Otolaryngology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

La presente invención se refiere a un mAb que se une específicamente a IL-1a que es útil para el tratamiento de enfermedades asociadas con tumores en seres humanos.
MX2016013346A 2010-08-23 2011-08-23 Anticuerpo anti-il-1a para usarse en el tratamiento de cáncer metastásico. MX388939B (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US37609710P 2010-08-23 2010-08-23
US40675910P 2010-10-26 2010-10-26
US41118310P 2010-11-08 2010-11-08
US201161480635P 2011-04-29 2011-04-29
PCT/US2011/048747 WO2012027324A2 (en) 2010-08-23 2011-08-23 Treatment for neoplastic diseases

Publications (1)

Publication Number Publication Date
MX388939B true MX388939B (es) 2025-03-20

Family

ID=45594256

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2016013346A MX388939B (es) 2010-08-23 2011-08-23 Anticuerpo anti-il-1a para usarse en el tratamiento de cáncer metastásico.
MX2013002160A MX342776B (es) 2010-08-23 2011-08-23 Tratamiento de enfermedades neoplasticas.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2013002160A MX342776B (es) 2010-08-23 2011-08-23 Tratamiento de enfermedades neoplasticas.

Country Status (17)

Country Link
US (3) US10294296B2 (es)
EP (3) EP2608808B1 (es)
JP (5) JP6241932B2 (es)
KR (7) KR20210128021A (es)
CN (3) CN103153340A (es)
AU (1) AU2011293554B9 (es)
DK (1) DK2608808T3 (es)
ES (2) ES2622482T3 (es)
IL (2) IL262856B (es)
MX (2) MX388939B (es)
NZ (1) NZ607472A (es)
PH (2) PH12013500316A1 (es)
PT (1) PT2608808T (es)
RU (2) RU2679119C2 (es)
SG (1) SG187853A1 (es)
WO (1) WO2012027324A2 (es)
ZA (1) ZA201301420B (es)

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US10975146B2 (en) 2018-06-29 2021-04-13 Cedars-Sinai Medical Center Interleukin-1 inhibition for combination treatment of pancreatic cancer

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Also Published As

Publication number Publication date
EP2608808B1 (en) 2017-01-18
RU2017112088A (ru) 2019-01-24
JP2013536236A (ja) 2013-09-19
US11932688B2 (en) 2024-03-19
JP6917681B2 (ja) 2021-08-11
RU2679119C2 (ru) 2019-02-06
IL262856A (en) 2018-12-31
EP3075394A1 (en) 2016-10-05
KR102748255B1 (ko) 2024-12-31
KR101910760B1 (ko) 2018-10-22
KR20160062200A (ko) 2016-06-01
EP2608808A4 (en) 2014-01-15
IL275350B (en) 2021-07-29
MX2013002160A (es) 2013-04-05
JP2021138750A (ja) 2021-09-16
IL262856B (en) 2020-06-30
EP3443985A1 (en) 2019-02-20
AU2011293554B2 (en) 2015-02-26
KR102314003B1 (ko) 2021-10-19
WO2012027324A3 (en) 2012-05-10
WO2012027324A2 (en) 2012-03-01
KR102104296B1 (ko) 2020-04-27
EP3443985B1 (en) 2020-12-16
EP3075394B1 (en) 2018-11-28
RU2017112088A3 (es) 2019-01-24
KR20200010609A (ko) 2020-01-30
ES2856723T3 (es) 2021-09-28
US10294296B2 (en) 2019-05-21
ZA201301420B (en) 2014-04-30
AU2011293554B9 (en) 2015-03-19
PH12013500316A1 (en) 2016-09-02
JP2019194233A (ja) 2019-11-07
PH12016500578A1 (en) 2017-03-06
KR20130108305A (ko) 2013-10-02
CN103153340A (zh) 2013-06-12
JP2025166117A (ja) 2025-11-05
US20120045444A1 (en) 2012-02-23
ES2622482T3 (es) 2017-07-06
KR20210128021A (ko) 2021-10-25
JP6241932B2 (ja) 2017-12-06
IL275350A (en) 2020-07-30
CN107252484A (zh) 2017-10-17
CN107281488A (zh) 2017-10-24
KR20240134401A (ko) 2024-09-09
EP2608808A2 (en) 2013-07-03
PT2608808T (pt) 2017-04-24
JP7316120B2 (ja) 2023-07-27
AU2011293554A1 (en) 2013-03-07
KR20170113687A (ko) 2017-10-12
SG187853A1 (en) 2013-03-28
KR20180116458A (ko) 2018-10-24
US20230382989A1 (en) 2023-11-30
MX342776B (es) 2016-10-12
DK2608808T3 (en) 2017-04-24
RU2013110030A (ru) 2014-09-27
US20190127460A1 (en) 2019-05-02
JP2016175939A (ja) 2016-10-06
NZ607472A (en) 2014-09-26
PH12016500578B1 (en) 2017-03-06
CN107281488B (zh) 2021-02-09

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