MX385475B - Derivados de piridoquinazolina eficaces como inhibidores de proteina quinasa - Google Patents
Derivados de piridoquinazolina eficaces como inhibidores de proteina quinasaInfo
- Publication number
- MX385475B MX385475B MX2019014436A MX2019014436A MX385475B MX 385475 B MX385475 B MX 385475B MX 2019014436 A MX2019014436 A MX 2019014436A MX 2019014436 A MX2019014436 A MX 2019014436A MX 385475 B MX385475 B MX 385475B
- Authority
- MX
- Mexico
- Prior art keywords
- protein kinase
- pyridoquinazoline
- kinase inhibitors
- derivatives useful
- diseases
- Prior art date
Links
- 229940045988 antineoplastic drug protein kinase inhibitors Drugs 0.000 title 1
- 239000003909 protein kinase inhibitor Substances 0.000 title 1
- NFRCNZHWCNHERP-UHFFFAOYSA-N pyrido[2,3-h]quinazoline Chemical class N1=CN=C2C3=CC=CN=C3C=CC2=C1 NFRCNZHWCNHERP-UHFFFAOYSA-N 0.000 title 1
- 102000001253 Protein Kinase Human genes 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 108060006633 protein kinase Proteins 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 230000001575 pathological effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F24—HEATING; RANGES; VENTILATING
- F24C—DOMESTIC STOVES OR RANGES ; DETAILS OF DOMESTIC STOVES OR RANGES, OF GENERAL APPLICATION
- F24C7/00—Stoves or ranges heated by electric energy
- F24C7/08—Arrangement or mounting of control or safety devices
- F24C7/082—Arrangement or mounting of control or safety devices on ranges, e.g. control panels, illumination
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F24—HEATING; RANGES; VENTILATING
- F24C—DOMESTIC STOVES OR RANGES ; DETAILS OF DOMESTIC STOVES OR RANGES, OF GENERAL APPLICATION
- F24C7/00—Stoves or ranges heated by electric energy
- F24C7/08—Arrangement or mounting of control or safety devices
- F24C7/087—Arrangement or mounting of control or safety devices of electric circuits regulating heat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Combustion & Propulsion (AREA)
- Mechanical Engineering (AREA)
- General Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES201730759 | 2017-06-01 | ||
| PCT/ES2018/070396 WO2018220252A1 (es) | 2017-06-01 | 2018-05-31 | Derivados de piridoquinazolina eficaces como inhibidores de proteína quinasa |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2019014436A MX2019014436A (es) | 2020-02-10 |
| MX385475B true MX385475B (es) | 2025-03-18 |
Family
ID=61569288
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2019014436A MX385475B (es) | 2017-06-01 | 2018-05-31 | Derivados de piridoquinazolina eficaces como inhibidores de proteina quinasa |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US11021479B2 (enExample) |
| EP (1) | EP3632912B1 (enExample) |
| JP (1) | JP7110335B2 (enExample) |
| KR (1) | KR102629854B1 (enExample) |
| CN (1) | CN111247143B (enExample) |
| AU (1) | AU2018278283B2 (enExample) |
| CA (1) | CA3066009A1 (enExample) |
| CY (1) | CY1124087T1 (enExample) |
| DK (1) | DK3632912T3 (enExample) |
| EA (1) | EA037384B1 (enExample) |
| ES (1) | ES2881960T3 (enExample) |
| HR (1) | HRP20210814T1 (enExample) |
| HU (1) | HUE054792T2 (enExample) |
| LT (1) | LT3632912T (enExample) |
| MX (1) | MX385475B (enExample) |
| PL (1) | PL3632912T3 (enExample) |
| PT (1) | PT3632912T (enExample) |
| RS (1) | RS61833B1 (enExample) |
| SI (1) | SI3632912T1 (enExample) |
| SM (1) | SMT202100312T1 (enExample) |
| WO (1) | WO2018220252A1 (enExample) |
| ZA (1) | ZA201908372B (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7525609B2 (ja) | 2020-01-31 | 2024-07-30 | エルジー エナジー ソリューション リミテッド | 多層構造の無機物層を含む分離膜一体型電極の製造方法及びそれによる分離膜一体型電極 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4551460A (en) | 1982-05-10 | 1985-11-05 | Hoffmann-La Roche Inc. | Pyrido[2,1-b]quinazoline derivatives useful as agents for treatment of allergic conditions and vascular disorders involving thrombosis |
| EP0944628B1 (en) * | 1996-11-26 | 2002-06-05 | American Cyanamid Company | Hetero-biaryl-pyridoquinazolinone derivatives as anti-cancer agents |
| US20050171172A1 (en) * | 2003-11-13 | 2005-08-04 | Ambit Biosciences Corporation | Amide derivatives as PDGFR modulators |
| AU2008345225A1 (en) * | 2007-12-21 | 2009-07-09 | University Of Rochester | Method for altering the lifespan of eukaryotic organisms |
| KR101361027B1 (ko) | 2008-11-28 | 2014-02-11 | 코와 가부시키가이샤 | 피리딘-3-카르복시아미드 유도체 |
| US11001581B2 (en) | 2014-03-20 | 2021-05-11 | The Johns Hopkins University and Lieber Institute, Inc. | Compounds which inhibit RNA polymerase, compositions including such compounds, and their use |
-
2018
- 2018-05-31 MX MX2019014436A patent/MX385475B/es unknown
- 2018-05-31 SM SM20210312T patent/SMT202100312T1/it unknown
- 2018-05-31 SI SI201830289T patent/SI3632912T1/sl unknown
- 2018-05-31 AU AU2018278283A patent/AU2018278283B2/en active Active
- 2018-05-31 PL PL18759146T patent/PL3632912T3/pl unknown
- 2018-05-31 DK DK18759146.6T patent/DK3632912T3/da active
- 2018-05-31 EP EP18759146.6A patent/EP3632912B1/en active Active
- 2018-05-31 US US16/615,867 patent/US11021479B2/en active Active
- 2018-05-31 PT PT187591466T patent/PT3632912T/pt unknown
- 2018-05-31 HR HRP20210814TT patent/HRP20210814T1/hr unknown
- 2018-05-31 RS RS20210545A patent/RS61833B1/sr unknown
- 2018-05-31 JP JP2020516962A patent/JP7110335B2/ja active Active
- 2018-05-31 KR KR1020197038842A patent/KR102629854B1/ko active Active
- 2018-05-31 ES ES18759146T patent/ES2881960T3/es active Active
- 2018-05-31 WO PCT/ES2018/070396 patent/WO2018220252A1/es not_active Ceased
- 2018-05-31 LT LTEP18759146.6T patent/LT3632912T/lt unknown
- 2018-05-31 EA EA201992793A patent/EA037384B1/ru unknown
- 2018-05-31 CN CN201880048531.4A patent/CN111247143B/zh active Active
- 2018-05-31 CA CA3066009A patent/CA3066009A1/en active Pending
- 2018-05-31 HU HUE18759146A patent/HUE054792T2/hu unknown
-
2019
- 2019-12-13 ZA ZA2019/08372A patent/ZA201908372B/en unknown
-
2021
- 2021-05-20 CY CY20211100437T patent/CY1124087T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RS61833B1 (sr) | 2021-06-30 |
| EA201992793A1 (ru) | 2020-03-26 |
| EA037384B1 (ru) | 2021-03-23 |
| HRP20210814T1 (hr) | 2021-06-25 |
| CA3066009A1 (en) | 2018-12-06 |
| CN111247143B (zh) | 2022-07-05 |
| SMT202100312T1 (it) | 2021-07-12 |
| EP3632912B1 (en) | 2021-03-17 |
| JP7110335B2 (ja) | 2022-08-01 |
| ES2881960T3 (es) | 2021-11-30 |
| JP2020521817A (ja) | 2020-07-27 |
| CN111247143A (zh) | 2020-06-05 |
| US20200148676A1 (en) | 2020-05-14 |
| US11021479B2 (en) | 2021-06-01 |
| DK3632912T3 (da) | 2021-05-10 |
| MX2019014436A (es) | 2020-02-10 |
| AU2018278283B2 (en) | 2021-06-17 |
| KR20200011990A (ko) | 2020-02-04 |
| SI3632912T1 (sl) | 2021-08-31 |
| KR102629854B1 (ko) | 2024-01-25 |
| CY1124087T1 (el) | 2022-05-27 |
| PL3632912T3 (pl) | 2021-09-06 |
| LT3632912T (lt) | 2021-06-10 |
| PT3632912T (pt) | 2021-06-02 |
| HUE054792T2 (hu) | 2021-09-28 |
| EP3632912A1 (en) | 2020-04-08 |
| WO2018220252A1 (es) | 2018-12-06 |
| AU2018278283A1 (en) | 2019-12-19 |
| BR112019024892A2 (pt) | 2020-06-16 |
| ZA201908372B (en) | 2021-04-28 |
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