ES2881960T3 - Inhibidores de proteina quinasa - Google Patents
Inhibidores de proteina quinasa Download PDFInfo
- Publication number
- ES2881960T3 ES2881960T3 ES18759146T ES18759146T ES2881960T3 ES 2881960 T3 ES2881960 T3 ES 2881960T3 ES 18759146 T ES18759146 T ES 18759146T ES 18759146 T ES18759146 T ES 18759146T ES 2881960 T3 ES2881960 T3 ES 2881960T3
- Authority
- ES
- Spain
- Prior art keywords
- oxo
- pyrido
- quinazoline
- carboxamide
- branched
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F24—HEATING; RANGES; VENTILATING
- F24C—DOMESTIC STOVES OR RANGES ; DETAILS OF DOMESTIC STOVES OR RANGES, OF GENERAL APPLICATION
- F24C7/00—Stoves or ranges heated by electric energy
- F24C7/08—Arrangement or mounting of control or safety devices
- F24C7/082—Arrangement or mounting of control or safety devices on ranges, e.g. control panels, illumination
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F24—HEATING; RANGES; VENTILATING
- F24C—DOMESTIC STOVES OR RANGES ; DETAILS OF DOMESTIC STOVES OR RANGES, OF GENERAL APPLICATION
- F24C7/00—Stoves or ranges heated by electric energy
- F24C7/08—Arrangement or mounting of control or safety devices
- F24C7/087—Arrangement or mounting of control or safety devices of electric circuits regulating heat
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Combustion & Propulsion (AREA)
- Mechanical Engineering (AREA)
- General Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
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| PCT/ES2018/070396 WO2018220252A1 (es) | 2017-06-01 | 2018-05-31 | Derivados de piridoquinazolina eficaces como inhibidores de proteína quinasa |
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| US4551460A (en) | 1982-05-10 | 1985-11-05 | Hoffmann-La Roche Inc. | Pyrido[2,1-b]quinazoline derivatives useful as agents for treatment of allergic conditions and vascular disorders involving thrombosis |
| EP0944628B1 (en) * | 1996-11-26 | 2002-06-05 | American Cyanamid Company | Hetero-biaryl-pyridoquinazolinone derivatives as anti-cancer agents |
| US20050171172A1 (en) * | 2003-11-13 | 2005-08-04 | Ambit Biosciences Corporation | Amide derivatives as PDGFR modulators |
| AU2008345225A1 (en) * | 2007-12-21 | 2009-07-09 | University Of Rochester | Method for altering the lifespan of eukaryotic organisms |
| KR101361027B1 (ko) | 2008-11-28 | 2014-02-11 | 코와 가부시키가이샤 | 피리딘-3-카르복시아미드 유도체 |
| US11001581B2 (en) | 2014-03-20 | 2021-05-11 | The Johns Hopkins University and Lieber Institute, Inc. | Compounds which inhibit RNA polymerase, compositions including such compounds, and their use |
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Also Published As
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| EA201992793A1 (ru) | 2020-03-26 |
| EA037384B1 (ru) | 2021-03-23 |
| HRP20210814T1 (hr) | 2021-06-25 |
| CA3066009A1 (en) | 2018-12-06 |
| CN111247143B (zh) | 2022-07-05 |
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| EP3632912B1 (en) | 2021-03-17 |
| JP7110335B2 (ja) | 2022-08-01 |
| JP2020521817A (ja) | 2020-07-27 |
| MX385475B (es) | 2025-03-18 |
| CN111247143A (zh) | 2020-06-05 |
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| US11021479B2 (en) | 2021-06-01 |
| DK3632912T3 (da) | 2021-05-10 |
| MX2019014436A (es) | 2020-02-10 |
| AU2018278283B2 (en) | 2021-06-17 |
| KR20200011990A (ko) | 2020-02-04 |
| SI3632912T1 (sl) | 2021-08-31 |
| KR102629854B1 (ko) | 2024-01-25 |
| CY1124087T1 (el) | 2022-05-27 |
| PL3632912T3 (pl) | 2021-09-06 |
| LT3632912T (lt) | 2021-06-10 |
| PT3632912T (pt) | 2021-06-02 |
| HUE054792T2 (hu) | 2021-09-28 |
| EP3632912A1 (en) | 2020-04-08 |
| WO2018220252A1 (es) | 2018-12-06 |
| AU2018278283A1 (en) | 2019-12-19 |
| BR112019024892A2 (pt) | 2020-06-16 |
| ZA201908372B (en) | 2021-04-28 |
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