MX384313B - Compuestos de amida, métodos de preparación y uso de los mismos como agentes para el tratamiento y prevención de enfermedades ocasionadas por virus que contienen arn y/o adn y enfermedades concomitantes. - Google Patents

Compuestos de amida, métodos de preparación y uso de los mismos como agentes para el tratamiento y prevención de enfermedades ocasionadas por virus que contienen arn y/o adn y enfermedades concomitantes.

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Publication number
MX384313B
MX384313B MX2016011771A MX2016011771A MX384313B MX 384313 B MX384313 B MX 384313B MX 2016011771 A MX2016011771 A MX 2016011771A MX 2016011771 A MX2016011771 A MX 2016011771A MX 384313 B MX384313 B MX 384313B
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MX
Mexico
Prior art keywords
treatment
dna
genus
prophylaxis
diseases caused
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MX2016011771A
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English (en)
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MX2016011771A (es
Inventor
Tatyana Alexandrovna Kromova
Vladimir Evgenievich Nebolsin
Original Assignee
Obschestvo S Ogranichennoi Otvetstvennostiyu Pharmenterprises
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Publication of MX2016011771A publication Critical patent/MX2016011771A/es
Publication of MX384313B publication Critical patent/MX384313B/es

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05—Dipeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A—HUMAN NECESSITIES
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    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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    • C07D209/04—Indoles; Hydrogenated indoles
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    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
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    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
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    • C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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Abstract

La presente invención se refiere a medicina e incluye un método para prevenir y tratar enfermedades causadas por virus que contienen ARN y ADN, y enfermedades concomitantes, en donde el método comprende el uso de una cantidad efectiva de compuestos de la fórmula general I o sales farmacéuticamente aceptables de la misma; la invención también se relaciona con métodos para preparar dichos compuestos, composiciones farmacéuticas para la prevención o tratamiento de enfermedades causadas por virus que contienen ARN y ADN, dichas composiciones comprenden una cantidad efectiva de un compuesto de la fórmula I o una sal farmacéuticamente aceptable del mismo; la invención trata con el objetivo de proporcionar un agente novedoso efectivo en el tratamiento de enfermedades causadas por un virus que contiene ARN perteneciente al género Enterovirus, Metapneumo virus, Pneumovirus, Respirovirus o Alfa-coronavirus, y/o por un virus que contiene ADN perteneciente a la familia Adenoviridae y/o Herpesviridae, y en la prevención y tratamiento de exacerbación de asma, enfermedad pulmonar obstructiva crónica, mucoviscidosis, conjuntivitis, gastroenteritis, hepatitis, miocarditis; en la prevención y tratamiento de rinorrea, rinitis infecciosa y aguda, faringitis, nasofaringitis, tonsilitis, laringitis, laringotraqueitis, laringotraqueobronquitis, bronquitis, bronquiolitis, neumonía o síndrome obstructivo de la vía aérea.
MX2016011771A 2014-03-12 2015-02-27 Compuestos de amida, métodos de preparación y uso de los mismos como agentes para el tratamiento y prevención de enfermedades ocasionadas por virus que contienen arn y/o adn y enfermedades concomitantes. MX384313B (es)

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RU2014109441A RU2628800C2 (ru) 2014-03-12 2014-03-12 Амидные соединения, способы получения, применение в качестве средств для лечения и профилактики заболеваний, вызываемых рнк-содержащими вирусами
PCT/RU2015/000121 WO2015137846A1 (ru) 2014-03-12 2015-02-27 Амидные соединения, способы их получения и применение

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MX2018009360A MX2018009360A (es) 2014-03-12 2016-09-09 Compuesto de amida y uso del mismo como agente para el tratamiento y prevencion de enfermedades ocasionadas por virus que contienen arn y/o adn, y enfermedades concomitantes.

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AU2018205206A1 (en) 2018-08-02
EA202090465A1 (ru) 2020-05-21
EA201891417A1 (ru) 2018-11-30
MX2018009360A (es) 2020-09-14
US20180362481A1 (en) 2018-12-20
JP2017511374A (ja) 2017-04-20
UA121468C2 (uk) 2020-06-10
EP3118211A4 (en) 2017-11-08
EA035545B1 (ru) 2020-07-06
EA201691694A1 (ru) 2017-01-30
RU2628800C2 (ru) 2017-08-22
IL247704A0 (en) 2016-11-30
AU2015230061B2 (en) 2019-09-05
US20170183318A1 (en) 2017-06-29
KR102410255B1 (ko) 2022-06-20
KR20160128416A (ko) 2016-11-07
CA2941900C (en) 2022-08-16
EA035439B1 (ru) 2020-06-15
CN109288837B (zh) 2021-04-30
WO2015137846A1 (ru) 2015-09-17
CN109288837A (zh) 2019-02-01
EP3431469A1 (en) 2019-01-23
AU2015230061A1 (en) 2016-09-22
KR20180088510A (ko) 2018-08-03

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