MX375960B - Proceso para la preparacion de pirazoles. - Google Patents

Proceso para la preparacion de pirazoles.

Info

Publication number
MX375960B
MX375960B MX2017001462A MX2017001462A MX375960B MX 375960 B MX375960 B MX 375960B MX 2017001462 A MX2017001462 A MX 2017001462A MX 2017001462 A MX2017001462 A MX 2017001462A MX 375960 B MX375960 B MX 375960B
Authority
MX
Mexico
Prior art keywords
formula
pyrazole
preparation
reagent
compounds
Prior art date
Application number
MX2017001462A
Other languages
English (en)
Other versions
MX2017001462A (es
Inventor
Birgit Gockel
Daniel Sälinger
Michael Rack
Sebastian Sörgel
Original Assignee
Basf Se
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Se filed Critical Basf Se
Publication of MX2017001462A publication Critical patent/MX2017001462A/es
Publication of MX375960B publication Critical patent/MX375960B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

La presente invención se refiere a un proceso para la preparación de un compuesto de pirazol de la fórmula V, que comprende la ciclación de un compuesto de carbonilo a,ß-insaturado sustituido por hidrazona de la fórmula IV por medio de la reacción con un reactivo adecuado, por ej., un agente reductor, un reactivo organometálico o un reactivo nucleófilo. Los compuestos de la fórmula y son herramientas versátiles de reacción para la preparación de productos químicos finos derivados de pirazol. La presente invención también se refiere a compuestos de pirazol de las fórmulas Va, Vb, Vc, y VI.
MX2017001462A 2014-07-31 2015-07-30 Proceso para la preparacion de pirazoles. MX375960B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP14179249 2014-07-31
PCT/EP2015/067507 WO2016016369A1 (en) 2014-07-31 2015-07-30 Process for preparing pyrazoles

Publications (2)

Publication Number Publication Date
MX2017001462A MX2017001462A (es) 2017-05-23
MX375960B true MX375960B (es) 2025-03-06

Family

ID=51257363

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017001462A MX375960B (es) 2014-07-31 2015-07-30 Proceso para la preparacion de pirazoles.

Country Status (19)

Country Link
US (2) US10414733B2 (es)
EP (1) EP3174858B1 (es)
JP (1) JP6625610B2 (es)
KR (1) KR102531217B1 (es)
CN (1) CN106573893B (es)
AU (1) AU2015295287B2 (es)
BR (1) BR112016030863B1 (es)
CA (1) CA2954212C (es)
DK (1) DK3174858T3 (es)
ES (1) ES2741831T3 (es)
IL (1) IL249730B (es)
MX (1) MX375960B (es)
PL (1) PL3174858T3 (es)
PT (1) PT3174858T (es)
RU (1) RU2712192C2 (es)
TR (1) TR201909606T4 (es)
UA (1) UA121395C2 (es)
WO (1) WO2016016369A1 (es)
ZA (1) ZA201701415B (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10093634B2 (en) 2013-12-18 2018-10-09 BASF Agro B.V. Process for the preparation of substituted phenoxyphenyl ketones
BR112016030863B1 (pt) 2014-07-31 2021-05-04 Basf Se processo para a preparação de um composto e compostos
US10167297B2 (en) 2014-10-24 2019-01-01 Basf Se Substituted pyridine compounds having herbicidal activity
BR112017023932A2 (pt) 2015-05-08 2018-07-17 Basf Agro Bv processo para a preparação de epóxido de terpinoleno
WO2016180614A1 (en) 2015-05-08 2016-11-17 Basf Se A process for the preparation of limonene-4-ol
ES2882543T3 (es) 2015-05-11 2021-12-02 Basf Se Proceso para la preparación de 4-amino-piridazinas
WO2017025454A1 (en) 2015-08-07 2017-02-16 Basf Se Control of pests in maize by ginkgolides and bilobalide
US10975036B2 (en) * 2016-02-02 2021-04-13 Basf Se Catalytic hydrogenation process for preparing pyrazoles
DK3472139T3 (da) 2016-06-15 2021-06-28 Basf Agro Bv Fremgangsmåde til epoxidering af en tetrasubstitueret alken
ES2833202T3 (es) 2016-06-15 2021-06-14 Basf Agro Bv Procedimiento para la epoxidación de un alqueno tetrasustituido
BR112018077104A2 (pt) 2016-07-07 2019-04-02 Basf Se compostos, processo para a preparação de compostos de fórmula i, processo para a preparação de compostos de fórmula iv e uso de compostos da fórmula i
EP3575286B1 (en) 2017-01-26 2022-05-11 Mitsui Chemicals Agro, Inc. Pyridone compound and bactericide for agricultural and horticultural use, which uses said compound as active ingredient
WO2018190351A1 (ja) 2017-04-10 2018-10-18 三井化学アグロ株式会社 ピリドン化合物およびそれを有効成分とする農園芸用殺菌剤
CA3059675A1 (en) 2017-04-10 2018-10-18 Mitsui Chemicals Agro, Inc. Pyridone compounds and agricultural and horticultural fungicides comprising the same as active ingredients
US11178870B2 (en) 2017-04-11 2021-11-23 Mitsui Chemicals Agro, Inc. Pyridone compounds and agricultural and horticultural fungicides containing the same as active ingredients
EP3636636B1 (en) 2017-06-08 2022-07-06 Mitsui Chemicals Agro, Inc. Pyridone compound and agricultural and horticultural fungicide
EP3728198A1 (en) * 2017-12-22 2020-10-28 Solvay Sa Process for the manufacture of pyrazole carboxylic derivatives and precursors thereof
US12114658B2 (en) 2018-07-25 2024-10-15 Mitsui Chemicals Crop & Life Solutions, Inc. Compounds having a nitrogen-containing unsaturated six-membered ring and agricultural and horticultural fungicides containing the same as active ingredients
EP3894403A1 (en) 2018-12-13 2021-10-20 Intervet International B.V. Process for preparing 1-[(3r,4s)-4-cyanotetrahydropyran-3-yl]-3-[(2-fluoro-6-methoxy-4-pyridyl)amino]p yrazole-4-carboxamide
EP4280398A1 (en) 2022-05-17 2023-11-22 NKT Photonics A/S Tunable laser device with frequency stabilization and low frequency-noise
CN116396221B (zh) * 2023-04-06 2024-09-10 无锡科华生物科技有限公司 一种1-(3-羟基-3-甲基-2-丁基)-5-甲基-1h-吡唑-4-羧酸的制备方法

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4728355A (en) 1985-10-10 1988-03-01 Fmc Corporation Pyridazinylurea plant regulators
TW406075B (en) 1994-12-13 2000-09-21 Upjohn Co Alkyl substituted piperidinyl and piperazinyl anti-AIDS compounds
DK0836605T3 (da) 1995-07-06 2002-05-13 Novartis Ag Pyrrolopyrimidiner og fremgangsmåder til deres fremstilling
US6258822B1 (en) 1997-08-06 2001-07-10 Abbott Laboratories Urokinase inhibitors
JP2004500314A (ja) 1998-06-05 2004-01-08 エギシュ　ヂョヂセルヂャール　エルテー ３（２ｈ）−ピリダジノン−４−置換アミノ−５−クロロ−誘導体の製法
HUP0203375A3 (en) 1999-07-28 2005-03-29 Aventis Pharm Prod Inc Substituted oxoazaheterocyclyl compounds
CA2449249A1 (en) 2001-06-12 2002-12-19 Merck & Co., Inc. Nr2b receptor antagonists for the treatment or prevention of migraines
JP2007326784A (ja) 2006-06-06 2007-12-20 Sagami Chem Res Center １−置換−５−フルオロアルキルピラゾール−４−カルボン酸エステルの製造方法
US20110189167A1 (en) 2007-04-20 2011-08-04 Flynn Daniel L Methods and Compositions for the Treatment of Myeloproliferative Diseases and other Proliferative Diseases
RU2516290C2 (ru) 2007-08-27 2014-05-20 Басф Се Пиразольные соединения и их использование в способе борьбы с беспозвоночными вредителями, в способе защиты материала размножения растений, в способе лечения или защиты животных от инвазии или инфицирования, в материале размножения растений и сельскохозяйственные композиции, содержащие пиразольные соединения
WO2009068652A1 (en) 2007-11-30 2009-06-04 Smithkline Beecham Corporation 2, 6-disubstituted pyridines and 2, 4-disubstituted pyrimidines as soluble guanylate cyclase activators
AU2009243550B2 (en) * 2008-05-05 2014-06-26 Basf Se Method for preparing 1,3,4-substituted pyrazol compounds
KR101600278B1 (ko) 2008-06-12 2016-03-08 얀센 파마슈티카 엔.브이. 히스타민 ｈ4 수용체의 다이아미노-피리딘, 피리미딘, 및 피리다진 조절제
CA2736538C (en) 2008-09-24 2018-02-20 Basf Se Pyrazole compounds for controlling invertebrate pests
US8853125B2 (en) 2008-09-24 2014-10-07 Basf Se Pyrazole compounds for controlling invertebrate pests
US20100113465A1 (en) 2008-10-30 2010-05-06 Pfizer Inc. 7-azaspiro[3.5]nonane-7-carboxamide compounds
EP2236505A1 (de) 2009-04-03 2010-10-06 Bayer CropScience AG Acylierte Aminopyridine und - pyridazine als Insektizide
AR076984A1 (es) 2009-06-08 2011-07-20 Merck Serono Sa Derivados de pirazol oxadiazol
JP5752691B2 (ja) 2009-09-29 2015-07-22 グラクソ グループ リミテッドＧｌａｘｏ Ｇｒｏｕｐ Ｌｉｍｉｔｅｄ 新規化合物
EP2555773A1 (de) 2010-04-08 2013-02-13 Boehringer Ingelheim International GmbH Arzneimittelkombinationen enthaltend pde4-inhibitoren und ep4-rezeptor-antagonisten
EP2468736A1 (en) 2010-12-23 2012-06-27 LEK Pharmaceuticals d.d. Synthesis of intermediates for preparing anacetrapib and derivates thereof
WO2012098387A1 (en) 2011-01-18 2012-07-26 Centro Nacional De Investigaciones Oncológicas (Cnio) 6, 7-ring-fused triazolo [4, 3 - b] pyridazine derivatives as pim inhibitors
CN103764055B (zh) 2011-04-12 2016-09-14 热医学公司 用于在流体增强型消融治疗中对流体进行加热的方法和装置
SI2699563T2 (sl) * 2011-04-21 2024-09-30 Basf Se Nove pesticidne spojine pirazola
WO2013004984A1 (en) 2011-07-07 2013-01-10 Centro Nacional De Investigaciones Oncologicas (Cnio) Tricyclic compounds for use as kinase inhibitors
EP2828262A4 (en) 2012-03-19 2015-09-23 Forum Pharmaceuticals Inc IMIDAZOTRIAZINONVERBINDUNGEN
JO3407B1 (ar) 2012-05-31 2019-10-20 Eisai R&D Man Co Ltd مركبات رباعي هيدرو بيرازولو بيريميدين
EP2671873A1 (en) 2012-06-06 2013-12-11 Solvay Sa Method for the cyclization of hydrazinoacrylic acid derivatives
WO2013189801A1 (en) * 2012-06-20 2013-12-27 Basf Se Pyrazole compound and pesticidal mixtures comprising a pyrazole compound
ES2834959T3 (es) * 2012-12-06 2021-06-21 Celgene Quanticel Res Inc Inhibidores de histona desmetilasa
UA112028C2 (uk) 2012-12-14 2016-07-11 Пфайзер Лімітед Похідні імідазопіридазину як модулятори гамка-рецептора
KR20160113719A (ko) 2014-01-31 2016-09-30 바스프 에스이 무척추동물 해충 방제용 피라졸
WO2015162133A1 (en) 2014-04-22 2015-10-29 Basf Se C3-c4-cycloalkenyl-comprising pyrazoles for controlling invertebrate pests
WO2015169734A1 (en) 2014-05-05 2015-11-12 Basf Se Pyrazoles for controlling invertebrate pests
WO2015189080A1 (en) 2014-06-12 2015-12-17 Basf Se Pesticidally active mixtures
BR112016030863B1 (pt) 2014-07-31 2021-05-04 Basf Se processo para a preparação de um composto e compostos
WO2016128239A1 (en) 2015-02-11 2016-08-18 Basf Se Pesticidal mixture comprising a pyrazole compound and a biopesticide
CR20170413A (es) 2015-02-11 2018-02-06 Basf Se Mezcla plaguicida que comprende un compuesto pirazol, un insecticida y un fungicida
WO2016128240A1 (en) 2015-02-11 2016-08-18 Basf Se Pesticidal mixture comprising a pyrazole compound and two fungicides
ES2882543T3 (es) 2015-05-11 2021-12-02 Basf Se Proceso para la preparación de 4-amino-piridazinas
US10975036B2 (en) 2016-02-02 2021-04-13 Basf Se Catalytic hydrogenation process for preparing pyrazoles

Also Published As

Publication number Publication date
CA2954212C (en) 2023-09-19
CN106573893A (zh) 2017-04-19
CA2954212A1 (en) 2016-02-04
TR201909606T4 (tr) 2019-07-22
KR20170036094A (ko) 2017-03-31
US10513498B2 (en) 2019-12-24
US20170210712A1 (en) 2017-07-27
JP6625610B2 (ja) 2019-12-25
RU2017106265A3 (es) 2019-02-25
WO2016016369A1 (en) 2016-02-04
US20190194141A1 (en) 2019-06-27
MX2017001462A (es) 2017-05-23
BR112016030863B1 (pt) 2021-05-04
US20180086715A9 (en) 2018-03-29
EP3174858B1 (en) 2019-04-17
PT3174858T (pt) 2019-07-23
UA121395C2 (uk) 2020-05-25
RU2017106265A (ru) 2018-08-30
RU2712192C2 (ru) 2020-01-24
IL249730B (en) 2019-12-31
ZA201701415B (en) 2019-06-26
EP3174858A1 (en) 2017-06-07
IL249730A0 (en) 2017-02-28
DK3174858T3 (da) 2019-07-15
AU2015295287B2 (en) 2019-07-04
JP2017522342A (ja) 2017-08-10
AU2015295287A1 (en) 2017-02-16
CN106573893B (zh) 2020-06-09
US10414733B2 (en) 2019-09-17
PL3174858T3 (pl) 2019-10-31
KR102531217B1 (ko) 2023-05-10
ES2741831T3 (es) 2020-02-12

Similar Documents

Publication Publication Date Title
MX375960B (es) Proceso para la preparacion de pirazoles.
AR132627A2 (es) Procesos para preparar compuestos intermediarios de utilidad para sintetizar compuestos de carbamoilpiridona policíclicos
PH12018502535B1 (en) Substituted carbonucleoside derivatives useful as anticancer agents
TW201613866A (en) Process for preparing fluorinated iminopyridine compounds
NZ726356A (en) Processes for preparing antiviral compounds
PH12017501413A1 (en) Substituted nucleoside derivatives useful as anticancer agents
MX391539B (es) Proceso de compuesto antifungico.
MX380550B (es) Sintesis de indazoles.
JOP20170100B1 (ar) توليف مركبات إندازول
CY1120763T1 (el) Νεες ενωσεις σουλφονυλαμινοβενζαμιδιου
MX2018011877A (es) Proceso mejorado para la preparacion de tartrato de butorfanol.
MX2019001393A (es) 1-hidroximetil-1,2,2,6-tetrametil-ciclohexano y sus derivados y su uso como productos quimicos aromaticos.
MX2019008375A (es) Tiobenzoimidazol como fungicidas.
MX2015017640A (es) Proceso para preparar compuestos de piridilpirazol y sus derivados de piridilhidrazina.
MX383114B (es) Proceso para la preparación de 3,5-bis(haloalquil)pirazoles por medio de la acilación de cetiminas.
MX369008B (es) Un proceso mejorado para la preparación de exametazima.
EA201892406A1 (ru) Способ получения гербицидных пиридинилимидазолоновых соединений
WO2018037428A3 (en) Process for the preparation of cyclic ketones
EA201791098A1 (ru) Способ синтеза производных бензазепина
CY1122343T1 (el) Μεθοδοι για την κατασκευη παραγωγων ινδαζολιου
MY190171A (en) Synthesis of indazoles
AR113298A2 (es) Método para preparar un derivado puenteado de pivalato a partir de escopolamina
TH1801006680A (th) การสังเคราะห์ของอินดาโซล
IN2013CH05394A (es)
TW201613924A (en) (Hetero)aryl imidazoles/pyrazoles

Legal Events

Date Code Title Description
FG Grant or registration