MX353427B - Composicion de recubrimiento adecuada para formas de dosis farmaceuticas o nutraceuticas. - Google Patents

Composicion de recubrimiento adecuada para formas de dosis farmaceuticas o nutraceuticas.

Info

Publication number
MX353427B
MX353427B MX2013014144A MX2013014144A MX353427B MX 353427 B MX353427 B MX 353427B MX 2013014144 A MX2013014144 A MX 2013014144A MX 2013014144 A MX2013014144 A MX 2013014144A MX 353427 B MX353427 B MX 353427B
Authority
MX
Mexico
Prior art keywords
pharmaceutical
core
coating composition
composition suitable
dosage forms
Prior art date
Application number
MX2013014144A
Other languages
English (en)
Other versions
MX2013014144A (es
Inventor
Meier Christian
Assmus Manfred
Nollenberger Kathrin
Hendrik Schattka Jan
Leubert René
Hermes Florian
Dassinger Thomas
Riermeier Thomas
Original Assignee
Evonik Roehm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evonik Roehm Gmbh filed Critical Evonik Roehm Gmbh
Publication of MX2013014144A publication Critical patent/MX2013014144A/es
Publication of MX353427B publication Critical patent/MX353427B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2/00—Processes of polymerisation
    • C08F2/12—Polymerisation in non-solvents
    • C08F2/16—Aqueous medium
    • C08F2/22—Emulsion polymerisation
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10—Esters
    • C08F220/12—Esters of monohydric alcohols or phenols
    • C08F220/16—Esters of monohydric alcohols or phenols of phenols or of alcohols containing two or more carbon atoms
    • C08F220/18—Esters of monohydric alcohols or phenols of phenols or of alcohols containing two or more carbon atoms with acrylic or methacrylic acids
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F265/00—Macromolecular compounds obtained by polymerising monomers on to polymers of unsaturated monocarboxylic acids or derivatives thereof as defined in group C08F20/00
    • C08F265/04—Macromolecular compounds obtained by polymerising monomers on to polymers of unsaturated monocarboxylic acids or derivatives thereof as defined in group C08F20/00 on to polymers of esters
    • C08F265/06—Polymerisation of acrylate or methacrylate esters on to polymers thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • General Preparation And Processing Of Foods (AREA)

Abstract

La invención se relaciona a una composición de recubrimiento adecuada para el recubrimiento de una forma de dosis farmacéutica o nutracéutica, que comprende un núcleo que comprende uno o más ingredientes activos farmacéuticos o nutracéuticos, en donde la composición de recubrimiento comprende por lo menos 20% en peso de una composición de polímero de núcleo/cubierta entérica derivada de un proceso de polimerización de emulsión, en donde ya sea el núcleo de la composición de polímero núcleo/cubierta es formada por un polímero o copolímero no reticulado, insoluble en agua y la cubierta de la composición de polímero de núcleo/cubierta es formada por un polímero o copolímero aniónico o viceversa.
MX2013014144A 2011-06-17 2011-06-17 Composicion de recubrimiento adecuada para formas de dosis farmaceuticas o nutraceuticas. MX353427B (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2011/060094 WO2012171575A1 (en) 2011-06-17 2011-06-17 Coating composition suitable for pharmaceutical or nutraceutical dosage forms

Publications (2)

Publication Number Publication Date
MX2013014144A MX2013014144A (es) 2014-01-23
MX353427B true MX353427B (es) 2018-01-12

Family

ID=44627582

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013014144A MX353427B (es) 2011-06-17 2011-06-17 Composicion de recubrimiento adecuada para formas de dosis farmaceuticas o nutraceuticas.

Country Status (17)

Country Link
US (1) US9844511B2 (es)
EP (1) EP2720682B1 (es)
JP (1) JP5847303B2 (es)
KR (1) KR101799624B1 (es)
CN (1) CN103608001B (es)
AU (1) AU2011370762A1 (es)
BR (1) BR112013032095A8 (es)
CA (1) CA2839689C (es)
ES (1) ES2616006T3 (es)
HK (1) HK1191572A1 (es)
HU (1) HUE033111T2 (es)
IL (1) IL229166B (es)
MX (1) MX353427B (es)
PL (1) PL2720682T3 (es)
RU (1) RU2606588C2 (es)
SI (1) SI2720682T1 (es)
WO (1) WO2012171575A1 (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9775815B2 (en) 2011-06-17 2017-10-03 Evonik Roehm Gmbh Gastric resistant pharmaceutical or nutraceutical composition with resistance against the influence of ethanol
JP6695337B2 (ja) * 2014-11-26 2020-05-20 レーム・ゲーエムベーハーＲｏｅｈｍ ＧｍｂＨ エタノールの影響に対する耐性を有する医薬品組成物または栄養機能食品組成物
JP2021503463A (ja) 2017-11-17 2021-02-12 エボニック オペレーションズ ゲーエムベーハー コーティングされた硬カプセルを製造する方法
CA3087238A1 (en) 2018-05-24 2019-11-28 Celanese EVA Performance Polymers Corporation Implantable device for sustained release of a macromolecular drug compound
AU2019275409A1 (en) 2018-05-24 2020-07-16 Celanese Eva Performance Polymers Llc Implantable device for sustained release of a macromolecular drug compound
KR20210099064A (ko) 2018-12-05 2021-08-11 에보니크 오퍼레이션즈 게엠베하 중합체성 입자의 제조 방법
JP2022525180A (ja) 2019-03-14 2022-05-11 エボニック オペレーションズ ゲーエムベーハー コア－シェルポリマーとセルロースとを含むカプセルシェル
US11406599B2 (en) 2019-04-30 2022-08-09 Evonik Operations Gmbh Pellet and multi-unit pellet system (MUPS)
US20220257517A1 (en) * 2019-06-13 2022-08-18 Evonik Operations Gmbh Powder composition comprising a copolymer mixture and a water-soluble cellulose
BR112023024450A2 (pt) 2021-05-25 2024-03-12 Evonik Operations Gmbh Cápsula de casca dura revestida com polímero, uso e processo de preparação da mesma
KR20240012433A (ko) 2021-05-25 2024-01-29 에보니크 오퍼레이션즈 게엠베하 변형 방출 코팅을 갖는 경질 쉘 캡슐
EP4176874A1 (en) 2021-11-09 2023-05-10 Evonik Operations GmbH Pharmaceutical or nutraceutical composition with an alcohol resistant single layer coating system
WO2023174722A1 (en) 2022-03-15 2023-09-21 Evonik Operations Gmbh Pre-functionalized hard shell capsule with accelerated drug release at ph value 5 to 5.5
WO2023214016A1 (en) 2022-05-06 2023-11-09 Evonik Operations Gmbh Dosage form with drug release at ph 3 to 6 using double coating system with at least one release acceleration agent

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2135073C3 (de) 1971-07-14 1974-07-11 Roehm Gmbh Überzugsmittel für Arzneiformen
US4330338A (en) * 1978-10-02 1982-05-18 Purdue Research Foundation Pharmaceutical coating composition, and preparation and dosages so coated
US4325856A (en) 1980-01-02 1982-04-20 The Dow Chemical Company Sequential emulsion polymerization process
DE3405378A1 (de) * 1984-02-15 1985-08-22 Röhm GmbH, 6100 Darmstadt Arzneimittelueberzug
US4916171A (en) * 1984-07-25 1990-04-10 Rohm And Haas Company Polymers comprising alkali-insoluble core/alkali-soluble shell and copositions thereof
US4677003A (en) * 1985-04-30 1987-06-30 Rohm And Haas Company Microsuspension process for preparing solvent core sequential polymer dispersion
US5643602A (en) * 1989-11-22 1997-07-01 Astra Aktiebolag Oral composition for the treatment of inflammatory bowel disease
DE9414065U1 (de) 1994-08-31 1994-11-03 Roehm Gmbh Thermoplastischer Kunststoff für darmsaftlösliche Arznei-Umhüllungen
DE9414066U1 (de) 1994-08-31 1994-11-03 Roehm Gmbh Überzugs- und Bindemittel für Arzneiformen sowie damit hergestellte Arzneiform
WO1997003112A1 (en) * 1995-07-07 1997-01-30 Mitsubishi Rayon Co., Ltd. Powdery material and modifier for cementitious material
DE10011447A1 (de) 2000-03-10 2001-09-20 Roehm Gmbh Dispersion mit nichtionischem Emulgator
DE10013029A1 (de) * 2000-03-17 2001-09-20 Roehm Gmbh Mehrschichtige Arzneiform für die Colonfreigabe
WO2002085335A1 (en) * 2001-04-18 2002-10-31 Nostrum Pharmaceuticals Inc. A novel coating for a sustained release pharmaceutical composition
US6827947B2 (en) * 2001-12-19 2004-12-07 Astrazeneca Ab Film coating
JP3640921B2 (ja) * 2001-12-28 2005-04-20 クラリアントポリマー株式会社 合成樹脂エマルジョン、それを含んでなる易水膨潤性粘着剤組成物、および合成樹脂エマルジョンの製造方法
DE10208335A1 (de) 2002-02-27 2003-09-04 Roehm Gmbh Arzneiform und Verfahren zu ihrer Herstellung
MXPA04010956A (es) 2003-01-30 2005-01-25 Roehm Gmbh Forma de dosis farmaceutica y metodo para la produccion de la misma.
GB2407501A (en) 2003-11-03 2005-05-04 Ist Superiore Sanita Nanoparticles for delivery of a pharmacologically active agent, comprising water insoluble (co)polymer core & hydrophilic acrylate-based (co)polymer shell
WO2005056619A1 (en) * 2003-12-15 2005-06-23 Council Of Scientific & Industrial Research pH SENSITIVE POLYMER AND PROCESS FOR PREPARATION THEREOF
DE102004011349A1 (de) 2004-03-05 2005-09-22 Basf Ag Wässrige Polymerdispersion auf Basis von Alkyl(meth)-acrylaten
US20060235131A1 (en) * 2005-04-15 2006-10-19 Hughes Kathleen A Process for preparing aqueous dispersions of multistage emulsion polymers
DE102006051020A1 (de) 2006-10-26 2008-04-30 Evonik Röhm Gmbh Verwendung von (Meth)acrylat-Copolymeren in Retard-Arzneiformen zur Verringerung des Einflusses von Ethanol auf die Wirkstofffreisetzung
US9700520B2 (en) 2007-09-21 2017-07-11 Evonik Roehm Gmbh PH-dependent controlled release pharmaceutical opioid composition with resistance against the influence of ethanol
WO2009036811A1 (en) 2007-09-21 2009-03-26 Evonik Röhm Gmbh Ph-dependent controlled release pharmaceutical composition for non-opioids with resistance against the influence of ethanol
EP2341899B1 (en) 2008-09-24 2014-12-17 Evonik Röhm GmbH Ph-dependent controlled release pharmaceutical opioid composition with resistance against the influence of ethanol
US10933024B2 (en) 2008-09-24 2021-03-02 Evonik Operations Gmbh PH-dependent controlled release pharmaceutical composition for non-opioids with resistance against the influence of ethanol
MX2011009667A (es) 2009-03-18 2011-12-14 Evonik Roehm Gmbh Composición farmacéutica de liberación controlada con resistencia a la influencia de etanol mediante el uso de un revestimiento compuesto de polímeros de vinilo neutrales y excipientes.
BRPI0924427A2 (pt) * 2009-03-18 2016-01-26 Evonik Roehm Gmbh composição farmacêutica de liberação controlada, seu processo de preparação e uso da mesma
BR112012002093A2 (pt) * 2009-07-30 2017-09-12 Evonik Roehm Gmbh Composição compreendendo um material polimérico aniônico e o sal de um ácido monocarboxílico saturado tendo 6 a 22 átomos de carbono

Also Published As

Publication number Publication date
ES2616006T3 (es) 2017-06-09
SI2720682T1 (sl) 2017-05-31
HK1191572A1 (en) 2014-08-01
BR112013032095A8 (pt) 2022-07-05
MX2013014144A (es) 2014-01-23
KR101799624B1 (ko) 2017-11-20
RU2014101227A (ru) 2015-09-27
JP5847303B2 (ja) 2016-01-20
AU2011370762A1 (en) 2013-11-14
RU2606588C2 (ru) 2017-01-10
US9844511B2 (en) 2017-12-19
CN103608001B (zh) 2015-10-14
CA2839689A1 (en) 2012-12-20
BR112013032095A2 (pt) 2016-12-13
US20140086997A1 (en) 2014-03-27
WO2012171575A1 (en) 2012-12-20
JP2014518205A (ja) 2014-07-28
CA2839689C (en) 2018-05-01
EP2720682B1 (en) 2016-11-23
KR20140041543A (ko) 2014-04-04
PL2720682T3 (pl) 2017-05-31
CN103608001A (zh) 2014-02-26
EP2720682A1 (en) 2014-04-23
IL229166B (en) 2018-01-31
HUE033111T2 (en) 2017-11-28
IL229166A0 (en) 2013-12-31

Similar Documents

Publication Publication Date Title
MX353427B (es) Composicion de recubrimiento adecuada para formas de dosis farmaceuticas o nutraceuticas.
MX353426B (es) Composicion de recubrimiento apropiada para formas de dosificacion farmaceuticas o nutraceuticas.
MX355662B (es) Composicion farmaceutica o nutraceutica de resistencia gastrica con resistencia contra la influencia de etanol.
MX347227B (es) Composicion farmaceutica o nutraceutica con liberacion sostenida caracteristica y con resistencia contra la influencia del etanol.
PH12015500106B1 (en) Novel 5-aminotetrahydroquinoline-2-carboxylic acids and use thereof
WO2013158814A8 (en) Immediate release, abuse deterrent pharmaceutical compositions
WO2015106128A3 (en) Rnai agents modified at the 4'-c-position
PH12017502326B1 (en) Orodispersible dosage unit containing an estetrol component
MX2016007914A (es) Microcapsulas hibridas.
WO2016190683A8 (ko) 길경 추출물을 함유하는 근육 질환 예방 및 치료용 또는 근 기능 개선용 조성물
NZ705578A (en) Coated pharmaceutical composition containing regorafenib
MX2017006858A (es) Composición farmacéutica o nutracéutica con resistencia a la influencia del etanol.
MX2015008295A (es) Composicion cosmetica.
WO2017136617A8 (en) Deuterated domperidone compositions and methods for therapy of disorders
TN2013000239A1 (en) New form of administration of enkephalinase inhibitor
WO2016190682A3 (ko) 모루신, 구와논 지 또는 상백피를 함유하는 근육 질환 예방 및 치료용 또는 근 기능 개선용 조성물
EA033448B1 (ru) Композиция орлистата и акарбозы с модифицированным высвобождением для лечения ожирения и связанных метаболических нарушений
WO2012162439A3 (en) Compositions comprising fusidic acid and packages therefor
SG11201810274RA (en) Hair treatment agent
BR112016025501A2 (pt) composição de revestimento
MX2015005762A (es) Producto de comicronizacion que comprende acetato de ulipristal.
BR112015009453A2 (pt) composição farmacêutica estável de peg-interferona alfa-2b
BR112017014016A2 (pt) método de redução da pressão intraocular, e, composição farmacêutica.
PH12014502836A1 (en) Medicament form for release of active ingredients
ZA201905664B (en) Novel dosage form

Legal Events

Date Code Title Description
FG Grant or registration