BR112013032095A8 - Composição de revestimento adequada para formas de dosagem farmacêuticas ou nutracêuticas - Google Patents

Composição de revestimento adequada para formas de dosagem farmacêuticas ou nutracêuticas

Info

Publication number
BR112013032095A8
BR112013032095A8 BR112013032095A BR112013032095A BR112013032095A8 BR 112013032095 A8 BR112013032095 A8 BR 112013032095A8 BR 112013032095 A BR112013032095 A BR 112013032095A BR 112013032095 A BR112013032095 A BR 112013032095A BR 112013032095 A8 BR112013032095 A8 BR 112013032095A8
Authority
BR
Brazil
Prior art keywords
pharmaceutical
core
coating
coating composition
composition suitable
Prior art date
Application number
BR112013032095A
Other languages
English (en)
Other versions
BR112013032095A2 (pt
Inventor
Hermes Florian
Hendrik Schattka Jan
Meier Christian
Nollenberger Kathrin
Leubert René
Assmus Manfred
Dassinger Thomas
Riermeier Thomas
Original Assignee
Evonik Roehm Gmbh
Roehm Gmbh
Evonik Degussa Gmbh
Evonik Operations Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evonik Roehm Gmbh, Roehm Gmbh, Evonik Degussa Gmbh, Evonik Operations Gmbh filed Critical Evonik Roehm Gmbh
Publication of BR112013032095A2 publication Critical patent/BR112013032095A2/pt
Publication of BR112013032095A8 publication Critical patent/BR112013032095A8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2/00—Processes of polymerisation
    • C08F2/12—Polymerisation in non-solvents
    • C08F2/16—Aqueous medium
    • C08F2/22—Emulsion polymerisation
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10—Esters
    • C08F220/12—Esters of monohydric alcohols or phenols
    • C08F220/16—Esters of monohydric alcohols or phenols of phenols or of alcohols containing two or more carbon atoms
    • C08F220/18—Esters of monohydric alcohols or phenols of phenols or of alcohols containing two or more carbon atoms with acrylic or methacrylic acids
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F265/00—Macromolecular compounds obtained by polymerising monomers on to polymers of unsaturated monocarboxylic acids or derivatives thereof as defined in group C08F20/00
    • C08F265/04—Macromolecular compounds obtained by polymerising monomers on to polymers of unsaturated monocarboxylic acids or derivatives thereof as defined in group C08F20/00 on to polymers of esters
    • C08F265/06—Polymerisation of acrylate or methacrylate esters on to polymers thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • General Preparation And Processing Of Foods (AREA)

Abstract

COMPOSIÇÃO DE REVESTIMENTO ADEQUADA PARA FORMAS DE DOSAGEM FARMACÊUTICAS OU NUTRACÊUTICAS. A presente invenção refere-se a uma composição de revestimento adequada para o revestimento de uma forma de dosagem farmacêutica ou nutracêutica, que compreende um núcleo que compreende um ou mais princípios ativos farmacêuticos ou nutracêuticos, em que a composição de revestimento é composta por, pelo menos, 20 % em peso de uma composição de polímero do núcleo/revestimento entérico derivado de um processo de polimerização em emulsão, em que tanto o núcleo da composição de polímero do núcleo/revestimento é formado por meio de um polímero ou copolímero insolúvel em água, não reticulado e o revestimento da composição de polímero do núcleo/revestimento é formado por meio de um polímero ou copolímero ou aniônico vice-versa.
BR112013032095A 2011-06-17 2011-06-17 Composição de revestimento adequada para formas de dosagem farmacêuticas ou nutracêuticas BR112013032095A8 (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2011/060094 WO2012171575A1 (en) 2011-06-17 2011-06-17 Coating composition suitable for pharmaceutical or nutraceutical dosage forms

Publications (2)

Publication Number Publication Date
BR112013032095A2 BR112013032095A2 (pt) 2016-12-13
BR112013032095A8 true BR112013032095A8 (pt) 2022-07-05

Family

ID=44627582

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112013032095A BR112013032095A8 (pt) 2011-06-17 2011-06-17 Composição de revestimento adequada para formas de dosagem farmacêuticas ou nutracêuticas

Country Status (17)

Country Link
US (1) US9844511B2 (pt)
EP (1) EP2720682B1 (pt)
JP (1) JP5847303B2 (pt)
KR (1) KR101799624B1 (pt)
CN (1) CN103608001B (pt)
AU (1) AU2011370762A1 (pt)
BR (1) BR112013032095A8 (pt)
CA (1) CA2839689C (pt)
ES (1) ES2616006T3 (pt)
HK (1) HK1191572A1 (pt)
HU (1) HUE033111T2 (pt)
IL (1) IL229166B (pt)
MX (1) MX353427B (pt)
PL (1) PL2720682T3 (pt)
RU (1) RU2606588C2 (pt)
SI (1) SI2720682T1 (pt)
WO (1) WO2012171575A1 (pt)

Families Citing this family (14)

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US9775815B2 (en) 2011-06-17 2017-10-03 Evonik Roehm Gmbh Gastric resistant pharmaceutical or nutraceutical composition with resistance against the influence of ethanol
JP6695337B2 (ja) * 2014-11-26 2020-05-20 レーム・ゲーエムベーハーＲｏｅｈｍ ＧｍｂＨ エタノールの影響に対する耐性を有する医薬品組成物または栄養機能食品組成物
JP2021503463A (ja) 2017-11-17 2021-02-12 エボニック オペレーションズ ゲーエムベーハー コーティングされた硬カプセルを製造する方法
CA3087238A1 (en) 2018-05-24 2019-11-28 Celanese EVA Performance Polymers Corporation Implantable device for sustained release of a macromolecular drug compound
AU2019275409A1 (en) 2018-05-24 2020-07-16 Celanese Eva Performance Polymers Llc Implantable device for sustained release of a macromolecular drug compound
KR20210099064A (ko) 2018-12-05 2021-08-11 에보니크 오퍼레이션즈 게엠베하 중합체성 입자의 제조 방법
JP2022525180A (ja) 2019-03-14 2022-05-11 エボニック オペレーションズ ゲーエムベーハー コア－シェルポリマーとセルロースとを含むカプセルシェル
US11406599B2 (en) 2019-04-30 2022-08-09 Evonik Operations Gmbh Pellet and multi-unit pellet system (MUPS)
US20220257517A1 (en) * 2019-06-13 2022-08-18 Evonik Operations Gmbh Powder composition comprising a copolymer mixture and a water-soluble cellulose
BR112023024450A2 (pt) 2021-05-25 2024-03-12 Evonik Operations Gmbh Cápsula de casca dura revestida com polímero, uso e processo de preparação da mesma
KR20240012433A (ko) 2021-05-25 2024-01-29 에보니크 오퍼레이션즈 게엠베하 변형 방출 코팅을 갖는 경질 쉘 캡슐
EP4176874A1 (en) 2021-11-09 2023-05-10 Evonik Operations GmbH Pharmaceutical or nutraceutical composition with an alcohol resistant single layer coating system
WO2023174722A1 (en) 2022-03-15 2023-09-21 Evonik Operations Gmbh Pre-functionalized hard shell capsule with accelerated drug release at ph value 5 to 5.5
WO2023214016A1 (en) 2022-05-06 2023-11-09 Evonik Operations Gmbh Dosage form with drug release at ph 3 to 6 using double coating system with at least one release acceleration agent

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BRPI0924427A2 (pt) * 2009-03-18 2016-01-26 Evonik Roehm Gmbh composição farmacêutica de liberação controlada, seu processo de preparação e uso da mesma
BR112012002093A2 (pt) * 2009-07-30 2017-09-12 Evonik Roehm Gmbh Composição compreendendo um material polimérico aniônico e o sal de um ácido monocarboxílico saturado tendo 6 a 22 átomos de carbono

Also Published As

Publication number Publication date
ES2616006T3 (es) 2017-06-09
SI2720682T1 (sl) 2017-05-31
HK1191572A1 (en) 2014-08-01
MX2013014144A (es) 2014-01-23
KR101799624B1 (ko) 2017-11-20
RU2014101227A (ru) 2015-09-27
MX353427B (es) 2018-01-12
JP5847303B2 (ja) 2016-01-20
AU2011370762A1 (en) 2013-11-14
RU2606588C2 (ru) 2017-01-10
US9844511B2 (en) 2017-12-19
CN103608001B (zh) 2015-10-14
CA2839689A1 (en) 2012-12-20
BR112013032095A2 (pt) 2016-12-13
US20140086997A1 (en) 2014-03-27
WO2012171575A1 (en) 2012-12-20
JP2014518205A (ja) 2014-07-28
CA2839689C (en) 2018-05-01
EP2720682B1 (en) 2016-11-23
KR20140041543A (ko) 2014-04-04
PL2720682T3 (pl) 2017-05-31
CN103608001A (zh) 2014-02-26
EP2720682A1 (en) 2014-04-23
IL229166B (en) 2018-01-31
HUE033111T2 (en) 2017-11-28
IL229166A0 (en) 2013-12-31

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06T Formal requirements before examination [chapter 6.20 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B12B Appeal against refusal [chapter 12.2 patent gazette]
B25D Requested change of name of applicant approved

Owner name: ROEHM GMBH (DE)

B25G Requested change of headquarter approved

Owner name: ROEHM GMBH (DE)

B25A Requested transfer of rights approved

Owner name: EVONIK DEGUSSA GMBH (DE)

B25D Requested change of name of applicant approved

Owner name: EVONIK OPERATIONS GMBH (DE)