MX353426B - Composicion de recubrimiento apropiada para formas de dosificacion farmaceuticas o nutraceuticas. - Google Patents
Composicion de recubrimiento apropiada para formas de dosificacion farmaceuticas o nutraceuticas.Info
- Publication number
- MX353426B MX353426B MX2013014143A MX2013014143A MX353426B MX 353426 B MX353426 B MX 353426B MX 2013014143 A MX2013014143 A MX 2013014143A MX 2013014143 A MX2013014143 A MX 2013014143A MX 353426 B MX353426 B MX 353426B
- Authority
- MX
- Mexico
- Prior art keywords
- pharmaceutical
- core
- coating composition
- composition suitable
- dosage forms
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5089—Processes
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F2/00—Processes of polymerisation
- C08F2/12—Polymerisation in non-solvents
- C08F2/16—Aqueous medium
- C08F2/22—Emulsion polymerisation
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
- C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
- C08F220/10—Esters
- C08F220/12—Esters of monohydric alcohols or phenols
- C08F220/16—Esters of monohydric alcohols or phenols of phenols or of alcohols containing two or more carbon atoms
- C08F220/18—Esters of monohydric alcohols or phenols of phenols or of alcohols containing two or more carbon atoms with acrylic or methacrylic acids
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F265/00—Macromolecular compounds obtained by polymerising monomers on to polymers of unsaturated monocarboxylic acids or derivatives thereof as defined in group C08F20/00
- C08F265/04—Macromolecular compounds obtained by polymerising monomers on to polymers of unsaturated monocarboxylic acids or derivatives thereof as defined in group C08F20/00 on to polymers of esters
- C08F265/06—Polymerisation of acrylate or methacrylate esters on to polymers thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L2207/00—Properties characterising the ingredient of the composition
- C08L2207/53—Core-shell polymer
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La presente invención se relaciona con una composición de recubrimiento apropiada para el recubrimiento de una forma de dosificación farmacéutica o nutracéutica, que comprende un centro que contiene uno o más ingredientes activos farmacéuticos o nutracéuticos, en donde la composición de recubrimiento comprende por lo menos 20% en peso de una composición polimérica entérica de centro/capa derivada de un proceso de polimerización en emulsión, en donde el centro de la composición polimérica de centro/capa se forma por un polímero o copolímero reticulado, insoluble en agua y la capa de la composición polimérica de centro/capa se forma por un polímero o copolímero aniónico.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/EP2011/060097 WO2012171576A1 (en) | 2011-06-17 | 2011-06-17 | Coating composition suitable for pharmaceutical or nutraceutical dosage forms |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2013014143A MX2013014143A (es) | 2014-01-23 |
MX353426B true MX353426B (es) | 2018-01-12 |
Family
ID=44627081
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2013014143A MX353426B (es) | 2011-06-17 | 2011-06-17 | Composicion de recubrimiento apropiada para formas de dosificacion farmaceuticas o nutraceuticas. |
Country Status (16)
Country | Link |
---|---|
US (1) | US9668977B2 (es) |
EP (1) | EP2720681B1 (es) |
JP (1) | JP5832645B2 (es) |
KR (1) | KR101799625B1 (es) |
CN (1) | CN103501767A (es) |
AU (1) | AU2011370763A1 (es) |
BR (1) | BR112013028453B8 (es) |
CA (1) | CA2839494C (es) |
ES (1) | ES2617402T3 (es) |
HU (1) | HUE033117T2 (es) |
IL (1) | IL228397A (es) |
MX (1) | MX353426B (es) |
PL (1) | PL2720681T3 (es) |
RU (1) | RU2599023C2 (es) |
SI (1) | SI2720681T1 (es) |
WO (1) | WO2012171576A1 (es) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9775815B2 (en) * | 2011-06-17 | 2017-10-03 | Evonik Roehm Gmbh | Gastric resistant pharmaceutical or nutraceutical composition with resistance against the influence of ethanol |
CN105943519A (zh) * | 2016-06-22 | 2016-09-21 | 福建省微生物研究所 | 一种苯磺贝他斯汀掩味颗粒 |
KR102408027B1 (ko) * | 2016-08-15 | 2022-06-15 | 에보니크 오퍼레이션즈 게엠베하 | 증진된 탈유화성 성능을 갖는 관능성 폴리알킬 (메트)아크릴레이트 |
EP3709979A1 (en) | 2017-11-17 | 2020-09-23 | Evonik Operations GmbH | Process for preparing a coated hard shell capsule |
JP2021524840A (ja) | 2018-05-24 | 2021-09-16 | セラニーズ・イーブイエイ・パフォーマンス・ポリマーズ・エルエルシー | 高分子薬剤化合物の持続放出用の埋め込み型デバイス |
SG11202005947RA (en) | 2018-05-24 | 2020-07-29 | Celanese Eva Performance Polymers Corp | Implantable device for sustained release of a macromolecular drug compound |
CN109232795A (zh) * | 2018-09-21 | 2019-01-18 | 佛山市森昂生物科技有限公司 | 一种防水型高韧性包衣材料的制备方法 |
WO2020221522A1 (en) | 2019-04-30 | 2020-11-05 | Evonik Operations Gmbh | Pellet and multi-unit pellet system (mups) |
US20220241155A1 (en) * | 2019-05-15 | 2022-08-04 | Evonik Operations Gmbh | Process for preparing filled hard-shell capsules with cellulose or starch-based coatings with a capsule-filling machine |
IL308701A (en) | 2021-05-25 | 2024-01-01 | Evonik Operations Gmbh | Hard shell capsules with modified release coating |
IL308707A (en) | 2021-05-25 | 2024-01-01 | Evonik Operations Gmbh | Capsule with a hard shell with prevention of the flow of gastric fluids |
EP4176874A1 (en) | 2021-11-09 | 2023-05-10 | Evonik Operations GmbH | Pharmaceutical or nutraceutical composition with an alcohol resistant single layer coating system |
WO2023174722A1 (en) | 2022-03-15 | 2023-09-21 | Evonik Operations Gmbh | Pre-functionalized hard shell capsule with accelerated drug release at ph value 5 to 5.5 |
WO2023214016A1 (en) | 2022-05-06 | 2023-11-09 | Evonik Operations Gmbh | Dosage form with drug release at ph 3 to 6 using double coating system with at least one release acceleration agent |
Family Cites Families (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2135073C3 (de) | 1971-07-14 | 1974-07-11 | Roehm Gmbh | Überzugsmittel für Arzneiformen |
US4876313A (en) * | 1986-08-29 | 1989-10-24 | Rohm And Haas Company | Grafted core-shell polymer compositions using polyfunctional compounds |
DE9414065U1 (de) | 1994-08-31 | 1994-11-03 | Röhm GmbH & Co. KG, 64293 Darmstadt | Thermoplastischer Kunststoff für darmsaftlösliche Arznei-Umhüllungen |
DE9414066U1 (de) | 1994-08-31 | 1994-11-03 | Röhm GmbH & Co. KG, 64293 Darmstadt | Überzugs- und Bindemittel für Arzneiformen sowie damit hergestellte Arzneiform |
DE19615812A1 (de) | 1996-04-20 | 1997-10-23 | Boehringer Mannheim Gmbh | Pharmazeutische Zubereitung enthaltend Diphosphonsäuren zur oralen Applikation |
AU771383B2 (en) * | 1998-12-08 | 2004-03-18 | Rohm And Haas Company | Dirt pickup resistant coating binder and coatings |
AUPQ164299A0 (en) | 1999-07-14 | 1999-08-05 | Orica Australia Pty Ltd | Aqueous polymer dispersion |
DE10208335A1 (de) | 2002-02-27 | 2003-09-04 | Roehm Gmbh | Arzneiform und Verfahren zu ihrer Herstellung |
MXPA04010956A (es) | 2003-01-30 | 2005-01-25 | Roehm Gmbh | Forma de dosis farmaceutica y metodo para la produccion de la misma. |
AU2003903838A0 (en) | 2003-07-23 | 2003-08-07 | Orica Australia Pty Ltd | Aqueous polymer dispersion |
TWI350762B (en) * | 2004-02-12 | 2011-10-21 | Euro Celtique Sa | Particulates |
EP1754766B1 (en) * | 2004-05-07 | 2011-08-17 | Asahi Kasei Chemicals Corporation | Aqueous resin dispersion for adhesive and composition thereof |
DE102004036437A1 (de) * | 2004-07-27 | 2006-03-23 | Röhm GmbH & Co. KG | Multipartikuläre Arzneiform für wenig lösliche Wirkstoffe, sowie ein Verfahren zur Herstellung der Arzneiform |
EP1811975A2 (en) * | 2004-10-19 | 2007-08-01 | The State of Oregon Acting by and | Enteric coated compositions that release active ingredient(s) in gastric fluid and intestinal fluid |
ITBO20050123A1 (it) | 2005-03-07 | 2005-06-06 | Alfa Wassermann Spa | Formulazioni farmaceutiche gastroresistenti contenenti rifaximina |
WO2006132471A1 (en) | 2005-06-07 | 2006-12-14 | Lg Chem, Ltd. | Polymeric lubricant having multi layer structure and manufacturing method thereof |
US20080014257A1 (en) * | 2006-07-14 | 2008-01-17 | Par Pharmaceutical, Inc. | Oral dosage forms |
US20080058473A1 (en) | 2006-08-31 | 2008-03-06 | Yakov Freidzon | Latex for low VOC paint having improved block resistance, open time and water-softening resistance |
DE102006051020A1 (de) | 2006-10-26 | 2008-04-30 | Evonik Röhm Gmbh | Verwendung von (Meth)acrylat-Copolymeren in Retard-Arzneiformen zur Verringerung des Einflusses von Ethanol auf die Wirkstofffreisetzung |
KR101454056B1 (ko) | 2007-09-21 | 2014-10-27 | 에보니크 룀 게엠베하 | 에탄올의 영향에 대하여 내성을 가지는 비-오피오이드용 ph-의존성 조절 방출 제약 조성물 |
CN101801357B (zh) | 2007-09-21 | 2013-08-07 | 赢创罗姆有限公司 | 耐受乙醇的影响的pH依赖性受控释放的药物组合物 |
CN102164589A (zh) | 2008-09-24 | 2011-08-24 | 赢创罗姆有限公司 | 耐受乙醇影响的非阿片类药物的pH依赖性受控释放的药物组合物 |
SI2341899T1 (sl) | 2008-09-24 | 2015-04-30 | Evonik Roehm Gmbh | Od pH odvisen opioidni farmacevtski sestavek z nadzorovanim sproščanjem z odpornostjo na vpliv etanola |
HUE032817T2 (en) | 2009-03-18 | 2017-11-28 | Evonik Roehm Gmbh | Regulated release pharmaceutical composition comprising a coating containing neutral vinyl polymers and excipients and resistant to the influence of ethanol |
BRPI0924427A2 (pt) | 2009-03-18 | 2016-01-26 | Evonik Roehm Gmbh | composição farmacêutica de liberação controlada, seu processo de preparação e uso da mesma |
CA2804929A1 (en) * | 2010-07-09 | 2012-01-12 | Lubrizol Advanced Materials, Inc. | Structured acrylate copolymer thickeners |
-
2011
- 2011-06-17 WO PCT/EP2011/060097 patent/WO2012171576A1/en active Application Filing
- 2011-06-17 JP JP2014515074A patent/JP5832645B2/ja not_active Expired - Fee Related
- 2011-06-17 AU AU2011370763A patent/AU2011370763A1/en not_active Abandoned
- 2011-06-17 CA CA2839494A patent/CA2839494C/en active Active
- 2011-06-17 CN CN201180070617.5A patent/CN103501767A/zh active Pending
- 2011-06-17 PL PL11725757T patent/PL2720681T3/pl unknown
- 2011-06-17 EP EP11725757.6A patent/EP2720681B1/en active Active
- 2011-06-17 SI SI201131105A patent/SI2720681T1/sl unknown
- 2011-06-17 MX MX2013014143A patent/MX353426B/es active IP Right Grant
- 2011-06-17 HU HUE11725757A patent/HUE033117T2/en unknown
- 2011-06-17 RU RU2014101228/15A patent/RU2599023C2/ru active
- 2011-06-17 KR KR1020137033078A patent/KR101799625B1/ko not_active Application Discontinuation
- 2011-06-17 US US14/115,632 patent/US9668977B2/en active Active
- 2011-06-17 BR BR112013028453A patent/BR112013028453B8/pt not_active IP Right Cessation
- 2011-06-17 ES ES11725757.6T patent/ES2617402T3/es active Active
-
2013
- 2013-09-12 IL IL228397A patent/IL228397A/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
JP2014517018A (ja) | 2014-07-17 |
RU2014101228A (ru) | 2015-07-27 |
ES2617402T3 (es) | 2017-06-19 |
KR101799625B1 (ko) | 2017-11-20 |
JP5832645B2 (ja) | 2015-12-16 |
CA2839494C (en) | 2018-11-06 |
PL2720681T3 (pl) | 2017-05-31 |
HUE033117T2 (en) | 2017-11-28 |
SI2720681T1 (sl) | 2017-03-31 |
US20140079792A1 (en) | 2014-03-20 |
BR112013028453B8 (pt) | 2022-07-05 |
KR20140041545A (ko) | 2014-04-04 |
IL228397A (en) | 2017-07-31 |
EP2720681A1 (en) | 2014-04-23 |
RU2599023C2 (ru) | 2016-10-10 |
US9668977B2 (en) | 2017-06-06 |
IL228397A0 (en) | 2013-12-31 |
AU2011370763A1 (en) | 2013-10-03 |
EP2720681B1 (en) | 2016-11-23 |
CN103501767A (zh) | 2014-01-08 |
BR112013028453A2 (pt) | 2017-01-24 |
CA2839494A1 (en) | 2012-12-20 |
MX2013014143A (es) | 2014-01-23 |
WO2012171576A1 (en) | 2012-12-20 |
BR112013028453B1 (pt) | 2021-10-19 |
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Legal Events
Date | Code | Title | Description |
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FG | Grant or registration |