MX351494B - Dispositivos y métodos para la estimulación eléctrica capacitiva no invasiva y su uso para la estimulación del nervio vago en el cuello de un paciente. - Google Patents

Dispositivos y métodos para la estimulación eléctrica capacitiva no invasiva y su uso para la estimulación del nervio vago en el cuello de un paciente.

Info

Publication number
MX351494B
MX351494B MX2013010215A MX2013010215A MX351494B MX 351494 B MX351494 B MX 351494B MX 2013010215 A MX2013010215 A MX 2013010215A MX 2013010215 A MX2013010215 A MX 2013010215A MX 351494 B MX351494 B MX 351494B
Authority
MX
Mexico
Prior art keywords
patient
neck
bursts
vagus nerve
nerve
Prior art date
Application number
MX2013010215A
Other languages
English (en)
Other versions
MX2013010215A (es
Inventor
P Errico Joseph
Simon Bruce
T Raffle John
Original Assignee
Electrocore Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US13/075,746 external-priority patent/US8874205B2/en
Application filed by Electrocore Llc filed Critical Electrocore Llc
Publication of MX2013010215A publication Critical patent/MX2013010215A/es
Publication of MX351494B publication Critical patent/MX351494B/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014External stimulators, e.g. with patch electrodes
    • A61N1/36021External stimulators, e.g. with patch electrodes for treatment of pain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0456Specially adapted for transcutaneous electrical nerve stimulation [TENS]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0472Structure-related aspects
    • A61N1/0492Patch electrodes
    • A61N1/0496Patch electrodes characterised by using specific chemical compositions, e.g. hydrogel compositions, adhesives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014External stimulators, e.g. with patch electrodes
    • A61N1/3603Control systems
    • A61N1/36034Control systems specified by the stimulation parameters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/40Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/10Drugs for disorders of the urinary system of the bladder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • A61M2021/0005Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus
    • A61M2021/0022Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus by the tactile sense, e.g. vibrations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • A61M2021/0005Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus
    • A61M2021/0027Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus by the hearing sense
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • A61M2021/0005Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus
    • A61M2021/0044Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus by the sight sense
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • A61M2021/0005Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus
    • A61M2021/0072Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus with application of electrical currents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014External stimulators, e.g. with patch electrodes
    • A61N1/36025External stimulators, e.g. with patch electrodes for treating a mental or cerebral condition
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36053Implantable neurostimulators for stimulating central or peripheral nerve system adapted for vagal stimulation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Radiology & Medical Imaging (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Psychology (AREA)
  • Psychiatry (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Acoustics & Sound (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Otolaryngology (AREA)
  • Hospice & Palliative Care (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Electrotherapy Devices (AREA)

Abstract

Un dispositivo de estimulación eléctrica no invasivo forma un campo eléctrico alargado de efecto que se puede orientar paralelo a un nervio largo, tal como un nervio vago en el cuello de un paciente, produciendo una respuesta fisiológica deseada en el paciente. El estimulador comprende una fuente de energía eléctrica, al menos un electrodo y un medio continuo eléctricamente conductor con el que el(los) electrodo(s) está(n) en contacto. El dispositivo de estimulación se configura para producir un voltaje máximo de pulso que es suficiente para producir un campo eléctrico fisiológicamente efectivo en el área adyacente de un nervio objetivo, pero no para estimular sustancialmente otros nervios y músculos que se encuentren entre las áreas adyacentes del nervio objetivo y la piel del paciente. La corriente pasa a través de los electrodos en ráfagas de cinco pulsos sinusoidales preferentemente, en donde cada pulso dentro de una ráfaga tiene una duración de 200 microsegundos preferentemente, y las ráfagas se repiten preferentemente a 15 - 50 ráfagas por segundo.
MX2013010215A 2011-03-10 2011-08-31 Dispositivos y métodos para la estimulación eléctrica capacitiva no invasiva y su uso para la estimulación del nervio vago en el cuello de un paciente. MX351494B (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161451259P 2011-03-10 2011-03-10
US13/075,746 US8874205B2 (en) 2009-03-20 2011-03-30 Device and methods for non-invasive electrical stimulation and their use for vagal nerve stimulation
US201161488208P 2011-05-20 2011-05-20
US13/183,765 US8874227B2 (en) 2009-03-20 2011-07-15 Devices and methods for non-invasive capacitive electrical stimulation and their use for vagus nerve stimulation on the neck of a patient
PCT/US2011/049844 WO2012121750A1 (en) 2011-03-10 2011-08-31 Devices and methods for non-invasive capacitive electrical stimulation and their use for vagus nerve stimulation on the neck of a patient

Publications (2)

Publication Number Publication Date
MX2013010215A MX2013010215A (es) 2014-04-25
MX351494B true MX351494B (es) 2017-10-17

Family

ID=46798501

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013010215A MX351494B (es) 2011-03-10 2011-08-31 Dispositivos y métodos para la estimulación eléctrica capacitiva no invasiva y su uso para la estimulación del nervio vago en el cuello de un paciente.

Country Status (10)

Country Link
US (4) US8874227B2 (es)
EP (4) EP2962724B8 (es)
JP (5) JP2014510586A (es)
CN (1) CN103517732B (es)
AU (4) AU2011361696B2 (es)
BR (1) BR112013023021B1 (es)
CA (1) CA2826835C (es)
IL (1) IL227868B (es)
MX (1) MX351494B (es)
WO (1) WO2012121750A1 (es)

Families Citing this family (167)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040226556A1 (en) 2003-05-13 2004-11-18 Deem Mark E. Apparatus for treating asthma using neurotoxin
US8660647B2 (en) * 2005-07-28 2014-02-25 Cyberonics, Inc. Stimulating cranial nerve to treat pulmonary disorder
US8874227B2 (en) * 2009-03-20 2014-10-28 ElectroCore, LLC Devices and methods for non-invasive capacitive electrical stimulation and their use for vagus nerve stimulation on the neck of a patient
US9119953B2 (en) * 2005-11-10 2015-09-01 ElectroCore, LLC Non-invasive treatment of a medical condition by vagus nerve stimulation
US11297445B2 (en) 2005-11-10 2022-04-05 Electrocore, Inc. Methods and devices for treating primary headache
US10537728B2 (en) 2005-11-10 2020-01-21 ElectroCore, LLC Vagal nerve stimulation to avert or treat stroke or transient ischemic attack
US9037247B2 (en) 2005-11-10 2015-05-19 ElectroCore, LLC Non-invasive treatment of bronchial constriction
US11351363B2 (en) 2005-11-10 2022-06-07 Electrocore, Inc. Nerve stimulation devices and methods for treating cardiac arrhythmias
US8483831B1 (en) 2008-02-15 2013-07-09 Holaira, Inc. System and method for bronchial dilation
KR101719824B1 (ko) 2008-05-09 2017-04-04 호라이라 인코포레이티드 기관지나무 치료용 시스템, 어셈블리 및 방법
US9333347B2 (en) 2010-08-19 2016-05-10 ElectroCore, LLC Devices and methods for non-invasive electrical stimulation and their use for vagal nerve stimulation on the neck of a patient
US9375571B2 (en) 2013-01-15 2016-06-28 ElectroCore, LLC Mobile phone using non-invasive nerve stimulation
US11229790B2 (en) 2013-01-15 2022-01-25 Electrocore, Inc. Mobile phone for treating a patient with seizures
US10376696B2 (en) 2009-03-20 2019-08-13 Electrocore, Inc. Medical self-treatment using non-invasive vagus nerve stimulation
US20190240486A1 (en) 2009-03-20 2019-08-08 Electrocore, Inc. Non-invasive treatment of neurodegenerative diseases
US9254383B2 (en) 2009-03-20 2016-02-09 ElectroCore, LLC Devices and methods for monitoring non-invasive vagus nerve stimulation
US9403001B2 (en) * 2009-03-20 2016-08-02 ElectroCore, LLC Non-invasive magnetic or electrical nerve stimulation to treat gastroparesis, functional dyspepsia, and other functional gastrointestinal disorders
US10512769B2 (en) 2009-03-20 2019-12-24 Electrocore, Inc. Non-invasive magnetic or electrical nerve stimulation to treat or prevent autism spectrum disorders and other disorders of psychological development
CN107049479B (zh) 2009-10-27 2020-10-16 努瓦拉公司 具有可冷却的能量发射组件的递送装置
CN106618731B (zh) 2009-11-11 2020-08-07 努瓦拉公司 用于处理组织和控制狭窄的系统、装置和方法
US8911439B2 (en) 2009-11-11 2014-12-16 Holaira, Inc. Non-invasive and minimally invasive denervation methods and systems for performing the same
US10441185B2 (en) 2009-12-16 2019-10-15 The Board Of Trustees Of The University Of Illinois Flexible and stretchable electronic systems for epidermal electronics
US9358381B2 (en) 2011-03-10 2016-06-07 ElectroCore, LLC Non-invasive vagal nerve stimulation to treat disorders
US12208263B2 (en) 2011-01-12 2025-01-28 Electrocore, Inc. Devices and methods for non-invasive vagal nerve stimulation
US11191953B2 (en) 2010-08-19 2021-12-07 Electrocore, Inc. Systems and methods for vagal nerve stimulation
US11400288B2 (en) 2010-08-19 2022-08-02 Electrocore, Inc Devices and methods for electrical stimulation and their use for vagus nerve stimulation on the neck of a patient
US12377260B2 (en) 2010-08-19 2025-08-05 Electrocord, Inc. Vagal nerve stimulation
US20200086108A1 (en) 2010-08-19 2020-03-19 Electrocore, Inc. Vagal nerve stimulation to reduce inflammation associated with an aneurysm
US12168121B2 (en) 2010-11-19 2024-12-17 Electrocore, Inc. Devices and methods for treating or preventing development disorders
US11432760B2 (en) 2011-01-12 2022-09-06 Electrocore, Inc. Devices and methods for remote therapy and patient monitoring
US11511109B2 (en) 2011-03-10 2022-11-29 Electrocore, Inc. Non-invasive magnetic or electrical nerve stimulation to treat gastroparesis, functional dyspepsia, and other functional gastrointestinal disorders
US11458297B2 (en) 2011-03-10 2022-10-04 Electrocore, Inc Electrical and magnetic stimulators used to treat migraine/sinus headache, rhinitis, sinusitis, rhinosinusitis, and comorbid disorders
US9764133B2 (en) 2012-01-13 2017-09-19 Modular Therapeutx, Llc Portable TENS apparatus and method of use thereof
WO2013106644A1 (en) * 2012-01-13 2013-07-18 Modular Therapeutx, Llc Portable tens apparatus and method of use thereof
US8972016B2 (en) 2012-01-13 2015-03-03 Modular Therapeutx, Llc Portable TENS apparatus and method of use thereof
CN105283122B (zh) * 2012-03-30 2020-02-18 伊利诺伊大学评议会 可共形于表面的可安装于附肢的电子器件
US9456916B2 (en) 2013-03-12 2016-10-04 Medibotics Llc Device for selectively reducing absorption of unhealthy food
US10537703B2 (en) 2012-11-26 2020-01-21 Thync Global, Inc. Systems and methods for transdermal electrical stimulation to improve sleep
US9440070B2 (en) 2012-11-26 2016-09-13 Thyne Global, Inc. Wearable transdermal electrical stimulation devices and methods of using them
US10485972B2 (en) 2015-02-27 2019-11-26 Thync Global, Inc. Apparatuses and methods for neuromodulation
US10814131B2 (en) 2012-11-26 2020-10-27 Thync Global, Inc. Apparatuses and methods for neuromodulation
WO2014082064A1 (en) 2012-11-26 2014-05-30 Thync, Inc. Wearable transdermal electrical stimulation devices and methods of using them
US9398933B2 (en) 2012-12-27 2016-07-26 Holaira, Inc. Methods for improving drug efficacy including a combination of drug administration and nerve modulation
US10293160B2 (en) 2013-01-15 2019-05-21 Electrocore, Inc. Mobile phone for treating a patient with dementia
EP3498332B1 (en) 2013-01-21 2021-07-14 Cala Health, Inc. Devices for controlling tremor
US12453853B2 (en) 2013-01-21 2025-10-28 Cala Health, Inc. Multi-modal stimulation for treating tremor
US9067070B2 (en) 2013-03-12 2015-06-30 Medibotics Llc Dysgeusia-inducing neurostimulation for modifying consumption of a selected nutrient type
US9011365B2 (en) 2013-03-12 2015-04-21 Medibotics Llc Adjustable gastrointestinal bifurcation (AGB) for reduced absorption of unhealthy food
EP2968928A1 (en) * 2013-03-15 2016-01-20 Nes Health, Ltd. Pulse polarity switching for improved human body stimulation and healing
US9427581B2 (en) 2013-04-28 2016-08-30 ElectroCore, LLC Devices and methods for treating medical disorders with evoked potentials and vagus nerve stimulation
US9242085B2 (en) 2013-06-28 2016-01-26 Boston Scientific Neuromodulation Corporation Transcutaneous electrical stimulation for treating neurological disorders
JP6410369B2 (ja) 2013-06-29 2018-10-24 セレヴァスト メディカル インク.Cerevast Medical Inc. 認知状態を修正又は誘発する経皮電気刺激装置
US10293161B2 (en) 2013-06-29 2019-05-21 Thync Global, Inc. Apparatuses and methods for transdermal electrical stimulation of nerves to modify or induce a cognitive state
EP3038699B1 (en) * 2013-08-27 2024-08-14 Flow Neuroscience, Inc. Electrode system for electrical stimulation
US9486618B2 (en) 2013-08-27 2016-11-08 Halo Neuro, Inc. Electrode system for electrical stimulation
US9782585B2 (en) 2013-08-27 2017-10-10 Halo Neuro, Inc. Method and system for providing electrical stimulation to a user
WO2015031517A1 (en) 2013-08-27 2015-03-05 Halo Neuro Inc. Method and system for providing electrical stimulation to a user
CA2926027A1 (en) 2013-10-02 2015-04-09 The Board Of Trustees Of The University Of Illinois Organ mounted electronics
US9610442B2 (en) * 2015-05-21 2017-04-04 The Governing Council Of The University Of Toronto Systems and methods for treatment of urinary dysfunction
CN106573138A (zh) 2014-02-27 2017-04-19 赛威医疗公司 用于神经刺激的用户控制的方法和装置
EP3148639A4 (en) * 2014-05-17 2018-04-18 Cerevast Medical Inc. Methods and apparatuses for the application of ensemble waveforms using transdermal neurostimulation
EP3145585B1 (en) * 2014-05-20 2021-11-03 electroCore, Inc. Non-invasive nerve stimulation via mobile devices
CN106794347B (zh) * 2014-05-23 2020-01-17 电核有限责任公司 用于迷走神经刺激的系统和方法
US9333334B2 (en) 2014-05-25 2016-05-10 Thync, Inc. Methods for attaching and wearing a neurostimulator
JP6588472B2 (ja) 2014-05-25 2019-10-09 ハイイン エクイティ インベストメント ファンド エル.ピー. ウェアラブル経皮神経刺激器
EP3148640B1 (en) 2014-06-02 2024-01-24 Cala Health, Inc. Systems for peripheral nerve stimulation to treat tremor
US10737093B2 (en) * 2014-07-03 2020-08-11 The Vitasken Venture Club Wearable item for increased application of nutrients
GB201421448D0 (en) 2014-12-03 2015-01-14 Armighorn Medical Ltd Oral muscle training
WO2016109851A1 (en) 2015-01-04 2016-07-07 Thync, Inc. Methods and apparatuses for transdermal stimulation of the outer ear
US11534608B2 (en) 2015-01-04 2022-12-27 Ist, Llc Methods and apparatuses for transdermal stimulation of the outer ear
WO2016113661A1 (en) 2015-01-13 2016-07-21 Siano Mobile Silicon Ltd. Treatment of headaches by electrical stimulation
US10441787B2 (en) * 2015-02-24 2019-10-15 Galvani Bioelectronics Limited Neuromodulation device
CN107872982B (zh) 2015-03-31 2022-10-28 昂科赛克医疗公司 用于改进的基于组织感测的电穿孔的系统和方法
CN107847732A (zh) 2015-05-29 2018-03-27 赛威医疗公司 用于经皮电刺激的方法和装置
EP3304430A4 (en) 2015-06-01 2019-03-06 The Board of Trustees of the University of Illionis MINIATURIZED ELECTRONIC SYSTEMS WITH WIRELESS AND CLOSE COMMUNICATION CAPABILITIES
KR20180034342A (ko) 2015-06-01 2018-04-04 더 보드 오브 트러스티즈 오브 더 유니버시티 오브 일리노이 대안적인 자외선 감지방법
CA2988586A1 (en) 2015-06-10 2016-12-15 Cala Health, Inc. Neuromodulation system for peripheral nerve stimulation with detachable therapy unit
US20180001107A1 (en) 2016-07-01 2018-01-04 Btl Holdings Limited Aesthetic method of biological structure treatment by magnetic field
CN108135537B (zh) 2015-07-31 2021-11-16 卡拉健康公司 用于治疗骨关节炎的系统、装置和方法
EP3337556B1 (en) * 2015-08-21 2022-05-25 Galvani Bioelectronics Limited Bronchodilator for use in a method of treating bronchoconstriction along with vagal nerve stimulation
CN108348746B (zh) 2015-09-23 2021-10-12 卡拉健康公司 用于手指或手中的周围神经刺激以治疗手震颤的系统和方法
CN108290037B (zh) 2015-10-26 2021-10-08 福禄神经学公司 电极定位系统及方法
WO2017106411A1 (en) 2015-12-15 2017-06-22 Cerevast Medical, Inc. Electrodes having surface exclusions
WO2017106878A1 (en) 2015-12-18 2017-06-22 Thync Global, Inc. Apparatuses and methods for transdermal electrical stimulation of nerves to modify or induce a cognitive state
US9956405B2 (en) 2015-12-18 2018-05-01 Thyne Global, Inc. Transdermal electrical stimulation at the neck to induce neuromodulation
EP3405251A4 (en) 2016-01-21 2019-08-28 Cala Health, Inc. SYSTEMS, METHODS AND DEVICES FOR PERIPHERAL NEUROMODULATION FOR THE TREATMENT OF DISEASES RELATED TO BUBBLE HYPERACTIVITY
US10583304B2 (en) 2016-01-25 2020-03-10 Setpoint Medical Corporation Implantable neurostimulator having power control and thermal regulation and methods of use
CN108778409B (zh) 2016-02-08 2022-04-08 哈洛纽罗公司 用于改善电刺激的提供的方法和系统
KR102494900B1 (ko) 2016-03-15 2023-02-01 나이키 이노베이트 씨.브이. 신발류를 위한 용량성 발 존재 감지
US11357290B2 (en) 2016-03-15 2022-06-14 Nike, Inc. Active footwear sensor calibration
US11026481B2 (en) 2016-03-15 2021-06-08 Nike, Inc. Foot presence signal processing using velocity
US11064768B2 (en) 2016-03-15 2021-07-20 Nike, Inc. Foot presence signal processing using velocity
CN105641807A (zh) * 2016-03-24 2016-06-08 江苏德长医疗科技有限公司 组合式程控神经肌肉电刺激装置
US11464993B2 (en) 2016-05-03 2022-10-11 Btl Healthcare Technologies A.S. Device including RF source of energy and vacuum system
US11534619B2 (en) 2016-05-10 2022-12-27 Btl Medical Solutions A.S. Aesthetic method of biological structure treatment by magnetic field
US10646708B2 (en) 2016-05-20 2020-05-12 Thync Global, Inc. Transdermal electrical stimulation at the neck
US10688274B1 (en) 2016-05-26 2020-06-23 Board Of Trustees Of The University Of Alabama, For And On Behalf Of The University Of Alabama In Huntsville Systems and methods for multi-modal and non-invasive stimulation of the nervous system
US10485443B2 (en) 2016-06-20 2019-11-26 Halo Neuro, Inc. Electrical interface system
IL264116B2 (en) 2016-07-08 2024-01-01 Cala Health Inc Systems and methods for stimulating n nerves with exactly n electrodes and improved dry electrodes
US11141219B1 (en) 2016-08-16 2021-10-12 BTL Healthcare Technologies, a.s. Self-operating belt
CN117959601A (zh) 2016-08-25 2024-05-03 卡拉健康公司 通过周围神经刺激治疗心脏机能障碍的系统和方法
KR102680648B1 (ko) * 2016-09-19 2024-07-02 닉스 테크놀로지스 엘티디 다기능 폐쇄 루프 신경 피드백 자극 디바이스 및 그 방법
US11357980B2 (en) 2016-09-29 2022-06-14 Theranica Bio-Electronics Ltd. Apparatus for applying an electrical signal to a subject
EP3548136B1 (en) 2016-12-01 2024-10-23 Hinge Health, Inc. Neuromodulation device
US10525255B2 (en) 2017-03-08 2020-01-07 Halo Neuro, Inc. System for electrical stimulation
EP3606604A4 (en) 2017-04-03 2020-12-16 Cala Health, Inc. PERIPHERAL NEUROMODULATION SYSTEMS, METHODS AND DEVICES FOR THE TREATMENT OF DISEASES ASSOCIATED WITH BLADDER HYPERACTIVITY
EP3630271B1 (en) 2017-05-21 2023-11-01 Theranica Bio-Electronics Ltd. Apparatus for providing pain relief therapy
JP6648731B2 (ja) * 2017-05-22 2020-02-14 京セラドキュメントソリューションズ株式会社 画像形成装置、及び画像形成システム
WO2019060298A1 (en) 2017-09-19 2019-03-28 Neuroenhancement Lab, LLC METHOD AND APPARATUS FOR NEURO-ACTIVATION
KR102651846B1 (ko) * 2017-10-11 2024-03-27 스팀비아 에스.알.오. 신경 조절 전극 어셈블리
US20240299745A1 (en) * 2017-10-13 2024-09-12 Setpoint Medical Corporation Reversing demyelination
US10507324B2 (en) 2017-11-17 2019-12-17 Halo Neuro, Inc. System and method for individualizing modulation
US11717686B2 (en) 2017-12-04 2023-08-08 Neuroenhancement Lab, LLC Method and apparatus for neuroenhancement to facilitate learning and performance
US11590341B2 (en) 2017-12-22 2023-02-28 Electrocore, Inc Vagal nerve stimulation therapy
US11273283B2 (en) 2017-12-31 2022-03-15 Neuroenhancement Lab, LLC Method and apparatus for neuroenhancement to enhance emotional response
US12280219B2 (en) 2017-12-31 2025-04-22 NeuroLight, Inc. Method and apparatus for neuroenhancement to enhance emotional response
EP3740274A4 (en) 2018-01-17 2021-10-27 Cala Health, Inc. SYSTEMS AND METHODS FOR TREATING INFLAMMATORY INTESTINAL DISEASE USING PERIPHERAL NERVE STIMULATION
CN108283760A (zh) * 2018-03-09 2018-07-17 广州圆医生物科技有限公司 一种肌肉神经多区域刺激仪
RU186964U1 (ru) * 2018-04-17 2019-02-11 Артем Олегович Кузнецов Устройство безоперационного восстановления опорно-двигательной функции парализованных частей тела и стимуляции поврежденных нервных окончаний
US11364361B2 (en) 2018-04-20 2022-06-21 Neuroenhancement Lab, LLC System and method for inducing sleep by transplanting mental states
US11278724B2 (en) 2018-04-24 2022-03-22 Thync Global, Inc. Streamlined and pre-set neuromodulators
EP3784325A4 (en) * 2018-04-26 2022-01-26 Hoolest Performance Technologies, Inc. Non-invasive nerve stimulation devices, electrode assemblies, and methods of use thereof
CN108434599A (zh) * 2018-05-29 2018-08-24 上海交通大学医学院附属第九人民医院 一种便携式经皮神经电刺激器
EP3603737B1 (en) 2018-07-31 2020-08-26 Flow Neuroscience AB Positioning of electrodes for transcranial brain stimulation
EP3849410A4 (en) 2018-09-14 2022-11-02 Neuroenhancement Lab, LLC SYSTEM AND METHODS FOR ENHANCEMENT OF SLEEP
WO2020068830A1 (en) 2018-09-24 2020-04-02 Vivek Sharma Auricular nerve stimulation to address patient disorders, and associated systems and methods
EP3866910A1 (en) 2018-10-17 2021-08-25 Signifier Medical Technologies Limited Oral muscle training
GB2573028B (en) 2018-10-17 2020-04-29 Signifier Medical Tech Limited Oral muscle training
EP3563896A1 (en) * 2018-11-07 2019-11-06 Thaler, Stephen L. Devices and methods for attracting enhanced attention
US12390638B2 (en) 2018-10-17 2025-08-19 Signifier Medical Technologies Limited Oral muscle training
JP7373565B2 (ja) 2018-11-20 2023-11-02 エヌユーエネルキ, インコーポレイテッド 反比例の関係にある周波数とピーク電圧を印加する電気刺激装置
AU2019398172B2 (en) 2018-12-12 2024-02-15 Battelle Memorial Institute Electrical stimulation devices and systems for safely operating such devices
WO2020150737A1 (en) 2019-01-18 2020-07-23 Ist, Llc Methods and devices for modulation of integrated neural networks to influence composite sensory processes
US11071860B2 (en) 2019-02-06 2021-07-27 Oncosec Medical Incorporated Systems and methods for detecting fault conditions in electroporation therapy
US12156689B2 (en) 2019-04-11 2024-12-03 Btl Medical Solutions A.S. Methods and devices for aesthetic treatment of biological structures by radiofrequency and magnetic energy
ES2988162T3 (es) 2019-04-11 2024-11-19 Btl Medical Solutions A S Dispositivos para el tratamiento estético de estructuras biológicas mediante radiofrecuencia y energía magnética
US12558146B2 (en) 2019-04-11 2026-02-24 Btl Medical Solutions A.S. Methods and devices for aesthetic treatment of biological structures by radiofrequency and magnetic energy
US12251560B1 (en) 2019-08-13 2025-03-18 Cala Health, Inc. Connection quality determination for wearable neurostimulation systems
CN112618951A (zh) * 2019-09-24 2021-04-09 上海微创医疗器械(集团)有限公司 一种电刺激信号发生器、电刺激系统及控制电极的方法
US11890468B1 (en) 2019-10-03 2024-02-06 Cala Health, Inc. Neurostimulation systems with event pattern detection and classification
CA3157779A1 (en) * 2019-10-18 2021-04-22 Stimit Ag Stimulation device and use thereof
WO2021107649A2 (ko) * 2019-11-29 2021-06-03 (주)와이브레인 환자의 신경에 전기적인 자극을 가하여 신경을 조절하는 장치 및 그 방법
USD1008700S1 (en) 2021-02-08 2023-12-26 Jonathan A. Shanker Neck therapy cushion
US11833368B2 (en) 2020-02-11 2023-12-05 Jonathan A. Shanker Systems and methods for delivering low-level electromagnetic radiation to a patient
US20210244960A1 (en) * 2020-02-11 2021-08-12 Jonathan A. Shanker Systems and methods for delivering low-level electromagnetic radiation to a patient
CN111450413B (zh) * 2020-04-09 2022-02-11 吉林大学 脑卒中患者触觉康复治疗系统
EP4146335B1 (en) 2020-05-04 2024-11-13 BTL Healthcare Technologies a.s. Device for unattended treatment of a patient
US11878167B2 (en) 2020-05-04 2024-01-23 Btl Healthcare Technologies A.S. Device and method for unattended treatment of a patient
WO2021241838A1 (ko) * 2020-05-27 2021-12-02 서울대학교산학협력단 전기자극을 이용한 세균 및 바이러스성 질병 치료 장치
EP4168103A4 (en) * 2020-06-22 2024-06-26 The Regents of the University of California NON-INVASIVE PERIPHERAL NERVE STIMULATION FOR ENHANCEMENT OF BEHAVIORAL THERAPY
TWI830958B (zh) * 2020-10-16 2024-02-01 瑞士商諾沃庫勒有限責任公司 用於判定傳感器陣列在個體之身體上之最佳位置以及規劃電極元件集合在個體之身體上之定位的方法
CN112843488B (zh) * 2021-01-28 2022-05-13 北京航空航天大学 一种光电刺激脉冲生成方法和装置
US12432510B2 (en) * 2021-03-24 2025-09-30 Tinnitech Ltd Integrated chemical-physical system for treating tinnitus
US12357817B2 (en) 2021-04-06 2025-07-15 Aerin Medical Inc. Nasal neuromodulation devices and methods
WO2023062563A1 (en) 2021-10-13 2023-04-20 Btl Medical Solutions A.S. Devices for aesthetic treatment of biological structures by radiofrequency and magnetic energy
TR2021016189A2 (tr) * 2021-10-18 2021-11-22 Revotera Medikal Teknolojiler Anonim Sirketi Kapasi̇tans tabanli dc şarj-deşarj kanser tedavi̇ ci̇hazi ve yöntemi̇
US11896816B2 (en) 2021-11-03 2024-02-13 Btl Healthcare Technologies A.S. Device and method for unattended treatment of a patient
CN114042249B (zh) * 2021-11-16 2024-06-04 天津工业大学 不同模式hf-emf磁刺激对海马区癫痫放电活动调控效应的对比分析方法
CN114343650B (zh) * 2021-12-09 2024-07-23 中国科学院深圳先进技术研究院 一种电聚合改性的柔性触头以及含有所述柔性触头的半干电极和脑电帽
CN114343651B (zh) * 2021-12-09 2024-08-09 中国科学院深圳先进技术研究院 一种具有梯度孔隙率的柔性触头及其包含该柔性触头的凝胶半干电极和脑电帽
NL2031921B1 (en) * 2022-05-18 2023-11-27 Qmedic B V An electrical nerve stimulation system for stimulating one or more nerves of a mammal with an electrical signal.
KR20250160437A (ko) * 2023-03-09 2025-11-13 가부시키가이샤 엠티지 전기 자극 장치
CN116899116B (zh) * 2023-04-25 2024-04-02 秦皇岛嘎哈医疗电子仪器有限公司 一种能适应不同人鼻、颈生理曲度的多穴位强磁激光脉冲电鼻炎治疗仪
WO2025019316A1 (en) * 2023-07-14 2025-01-23 Board Of Regents, The University Of Texas System Methods and systems for closed loop vagus nerve stimulation triggering
WO2025219749A1 (en) * 2024-04-20 2025-10-23 Abdolahad Mohammad Variable-distance finger probe for electrical stimulation of target cells
CN119280668B (zh) * 2024-08-12 2025-10-10 苏州穹顶医疗技术有限公司 一种基于时间干涉的增强型无创脑深部电刺激系统和方法
US12564726B1 (en) 2024-10-08 2026-03-03 Btl Medical Solutions A.S. Devices and methods for application of a magnetic field to the nervous system

Family Cites Families (132)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR446660A (fr) 1911-09-02 1912-12-12 Gottlieb Schuettel Dispositif pour métiers continus à anneaux pour monter les curseurs sur les anneaux
US3077884A (en) 1957-06-13 1963-02-19 Batrow Lab Inc Electro-physiotherapy apparatus
US3279468A (en) 1963-05-14 1966-10-18 Vine Sidney Le Electrotherapeutic facial mask apparatus
US3568662A (en) 1967-07-07 1971-03-09 Donald B Everett Method and apparatus for sensing bioelectric potentials
US3590810A (en) 1968-05-27 1971-07-06 Honeywell Inc Biomedical body electrode
US3659614A (en) 1969-12-29 1972-05-02 Bernard Jankelson Adjustable headband carrying electrodes for electrically stimulating the facial and mandibular nerves
US3744482A (en) 1971-06-29 1973-07-10 Hittman Ass Inc Dry contact electrode with amplifier for physiological signals
US3817254A (en) 1972-05-08 1974-06-18 Medtronic Inc Transcutaneous stimulator and stimulation method
US3882846A (en) 1973-04-04 1975-05-13 Nasa Insulated electrocardiographic electrodes
US3862633A (en) 1974-05-06 1975-01-28 Kenneth C Allison Electrode
US3973557A (en) 1975-04-21 1976-08-10 Allison Kenneth C Electrode
US4220159A (en) 1976-04-23 1980-09-02 Biomedical International Company Electrode
US4166457A (en) 1976-08-16 1979-09-04 University Of Utah Research Institute Fluid self-sealing bioelectrode
US4144893A (en) 1976-09-22 1979-03-20 Batrow Laboratories, Inc. Neuromuscular therapy device
US4324253A (en) 1977-01-28 1982-04-13 Greene Ronald W Transcutaneous pain control and/or muscle stimulating apparatus
US4182346A (en) 1977-06-02 1980-01-08 Biomedical International Company Electrode
US4215696A (en) 1978-03-20 1980-08-05 Graphic Controls Corporation Biomedical electrode with pressurized skin contact
US4177819A (en) 1978-03-30 1979-12-11 Kofsky Harvey I Muscle stimulating apparatus
US4196737A (en) 1978-04-21 1980-04-08 C. R. Bard, Inc. Transcutaneous electrode construction
CA1105565A (en) 1978-09-12 1981-07-21 Kaufman (John G.) Hospital Products Ltd. Electrosurgical electrode
US4669468A (en) 1979-06-15 1987-06-02 American Hospital Supply Corporation Capacitively coupled indifferent electrode
US4503863A (en) 1979-06-29 1985-03-12 Katims Jefferson J Method and apparatus for transcutaneous electrical stimulation
US4458696A (en) 1979-08-07 1984-07-10 Minnesota Mining And Manufacturing Company T.E.N.S. Electrode
US4383529A (en) 1980-11-03 1983-05-17 Wescor, Inc. Iontophoretic electrode device, method and gel insert
US4387714A (en) 1981-05-13 1983-06-14 Purdue Research Foundation Electrosurgical dispersive electrode
EP0085327B1 (en) * 1982-01-18 1986-04-30 Medtronic, Inc. Electrically conductive compositions and electrodes utilizing same
US4702254A (en) 1983-09-14 1987-10-27 Jacob Zabara Neurocybernetic prosthesis
US5003978A (en) 1985-08-21 1991-04-02 Technology 21, Inc. Non-polarizable dry biomedical electrode
US4865048A (en) 1987-12-31 1989-09-12 Eckerson Harold D Method and apparatus for drug free neurostimulation
JPH0235755U (es) * 1988-08-31 1990-03-08
US5052391A (en) 1990-10-22 1991-10-01 R.F.P., Inc. High frequency high intensity transcutaneous electrical nerve stimulator and method of treatment
US5299569A (en) 1991-05-03 1994-04-05 Cyberonics, Inc. Treatment of neuropsychiatric disorders by nerve stimulation
WO1993001862A1 (en) 1991-07-22 1993-02-04 Cyberonics, Inc. Treatment of respiratory disorders by nerve stimulation
US5782874A (en) * 1993-05-28 1998-07-21 Loos; Hendricus G. Method and apparatus for manipulating nervous systems
US5487759A (en) 1993-06-14 1996-01-30 Bastyr; Charles A. Nerve stimulating device and associated support device
US5458141A (en) 1993-08-04 1995-10-17 Quinton Instrument Company Abrasive skin electrode
US5458625A (en) 1994-05-04 1995-10-17 Kendall; Donald E. Transcutaneous nerve stimulation device and method for using same
US5512057A (en) 1994-11-14 1996-04-30 Medserv Group, Inc. Interferential stimulator for applying localized stimulation
US5983131A (en) 1995-08-11 1999-11-09 Massachusetts Institute Of Technology Apparatus and method for electroporation of tissue
US5903516A (en) 1996-05-08 1999-05-11 Mayo Foundation For Medical Education And Research Acoustic force generator for detection, imaging and information transmission using the beat signal of multiple intersecting sonic beams
US6104956A (en) 1996-05-31 2000-08-15 Board Of Trustees Of Southern Illinois University Methods of treating traumatic brain injury by vagus nerve stimulation
JP4076232B2 (ja) 1996-06-06 2008-04-16 フラレックス・テラピューティクス・インコーポレーテッド 低周波数磁気パルスを使用する電気治療装置
US6029090A (en) 1997-01-27 2000-02-22 Herbst; Ewa Multi-functional electrical stimulation system
US6479523B1 (en) 1997-08-26 2002-11-12 Emory University Pharmacologic drug combination in vagal-induced asystole
US6757556B2 (en) 1998-05-26 2004-06-29 Ineedmd. Com Electrode sensor
US6463327B1 (en) 1998-06-11 2002-10-08 Cprx Llc Stimulatory device and methods to electrically stimulate the phrenic nerve
US20050137644A1 (en) 1998-10-26 2005-06-23 Boveja Birinder R. Method and system for vagal blocking and/or vagal stimulation to provide therapy for obesity and other gastrointestinal disorders
US6351674B2 (en) 1998-11-23 2002-02-26 Synaptic Corporation Method for inducing electroanesthesia using high frequency, high intensity transcutaneous electrical nerve stimulation
US6792306B2 (en) 2000-03-10 2004-09-14 Biophoretic Therapeutic Systems, Llc Finger-mounted electrokinetic delivery system for self-administration of medicaments and methods therefor
US6341236B1 (en) 1999-04-30 2002-01-22 Ivan Osorio Vagal nerve stimulation techniques for treatment of epileptic seizures
US6587719B1 (en) 1999-07-01 2003-07-01 Cyberonics, Inc. Treatment of obesity by bilateral vagus nerve stimulation
US6610713B2 (en) 2000-05-23 2003-08-26 North Shore - Long Island Jewish Research Institute Inhibition of inflammatory cytokine production by cholinergic agonists and vagus nerve stimulation
US6871099B1 (en) 2000-08-18 2005-03-22 Advanced Bionics Corporation Fully implantable microstimulator for spinal cord stimulation as a therapy for chronic pain
US6567695B1 (en) 2000-11-24 2003-05-20 Woodside Biomedical, Inc. Electro-acupuncture device with stimulation electrode assembly
US6738667B2 (en) 2000-12-28 2004-05-18 Medtronic, Inc. Implantable medical device for treating cardiac mechanical dysfunction by electrical stimulation
US6609025B2 (en) 2001-01-02 2003-08-19 Cyberonics, Inc. Treatment of obesity by bilateral sub-diaphragmatic nerve stimulation
US6735480B2 (en) 2001-06-29 2004-05-11 Abbott Laboratories Electro-acupuncture device with D-shaped stimulation electrodes
US8571653B2 (en) 2001-08-31 2013-10-29 Bio Control Medical (B.C.M.) Ltd. Nerve stimulation techniques
US7778711B2 (en) 2001-08-31 2010-08-17 Bio Control Medical (B.C.M.) Ltd. Reduction of heart rate variability by parasympathetic stimulation
US7904176B2 (en) 2006-09-07 2011-03-08 Bio Control Medical (B.C.M.) Ltd. Techniques for reducing pain associated with nerve stimulation
US7734355B2 (en) 2001-08-31 2010-06-08 Bio Control Medical (B.C.M.) Ltd. Treatment of disorders by unidirectional nerve stimulation
US7885709B2 (en) 2001-08-31 2011-02-08 Bio Control Medical (B.C.M.) Ltd. Nerve stimulation for treating disorders
AU2003212870A1 (en) 2002-02-01 2003-09-02 The Cleveland Clinic Foundation Methods of affecting hypothalamic-related conditions
EP1490148A2 (en) 2002-04-01 2004-12-29 Med-El Elektromedizinische Geräte GmbH Reducing effect of magnetic and electromagnetic fields on an implants magnet and/or electronic
US20120303080A1 (en) 2003-06-13 2012-11-29 Bio Control Medical (B.C.M.) Ltd. Parasympathetic nerve stimulation
KR100553516B1 (ko) 2002-06-24 2006-02-20 정종필 알파파유도 전기자극기
US7294101B2 (en) 2002-12-21 2007-11-13 Neuropace, Inc. Means and methods for treating headaches
US20040172084A1 (en) 2003-02-03 2004-09-02 Knudson Mark B. Method and apparatus for treatment of gastro-esophageal reflux disease (GERD)
US7153256B2 (en) 2003-03-07 2006-12-26 Neuronetics, Inc. Reducing discomfort caused by electrical stimulation
US20050187590A1 (en) 2003-05-11 2005-08-25 Boveja Birinder R. Method and system for providing therapy for autism by providing electrical pulses to the vagus nerve(s)
US7149574B2 (en) 2003-06-09 2006-12-12 Palo Alto Investors Treatment of conditions through electrical modulation of the autonomic nervous system
WO2005007120A2 (en) 2003-07-18 2005-01-27 The Johns Hopkins University System and method for treating nausea and vomiting by vagus nerve stimulation
US7418292B2 (en) 2003-10-01 2008-08-26 Medtronic, Inc. Device and method for attenuating an immune response
US20050075702A1 (en) 2003-10-01 2005-04-07 Medtronic, Inc. Device and method for inhibiting release of pro-inflammatory mediator
US8190248B2 (en) 2003-10-16 2012-05-29 Louisiana Tech University Foundation, Inc. Medical devices for the detection, prevention and/or treatment of neurological disorders, and methods related thereto
US8086318B2 (en) 2004-02-12 2011-12-27 Ndi Medical, Llc Portable assemblies, systems, and methods for providing functional or therapeutic neurostimulation
EP1742700A4 (en) 2004-03-02 2008-05-28 Cvrx Inc EXTERNAL ACTIVATION OF BAROREFLEX
JP4750784B2 (ja) 2004-04-23 2011-08-17 ノヴォキュアー・リミテッド 異なる周波数の電界による腫瘍等の治療
US7601115B2 (en) 2004-05-24 2009-10-13 Neuronetics, Inc. Seizure therapy method and apparatus
GB2414407B (en) * 2004-05-28 2009-04-15 Eumedic Ltd Treatment apparatus for applying electrical impulses to the body of a patient
US7173437B2 (en) 2004-06-10 2007-02-06 Quantum Applied Science And Research, Inc. Garment incorporating embedded physiological sensors
WO2006010013A1 (en) 2004-07-09 2006-01-26 Advanced Bionics Corporation Systems and methods for using a butterfly coil to communicate with or transfer power to an implantable medical device
US7245956B2 (en) 2004-07-15 2007-07-17 Quantum Applied Science & Research, Inc. Unobtrusive measurement system for bioelectric signals
EP1786510A4 (en) 2004-07-15 2009-12-02 Northstar Neuroscience Inc SYSTEMS AND METHOD FOR INCREASING OR INFLUENCING THE EFFICIENCY OR EFFECTIVENESS OF NEURAL STIMULATION
US7337005B2 (en) 2004-09-08 2008-02-26 Spinal Modulations, Inc. Methods for stimulating a nerve root ganglion
WO2006041648A2 (en) 2004-10-04 2006-04-20 Peerlead Medical, Inc. A capacitive medical electrode
US7613520B2 (en) 2004-10-21 2009-11-03 Advanced Neuromodulation Systems, Inc. Spinal cord stimulation to treat auditory dysfunction
WO2006061688A1 (en) 2004-12-07 2006-06-15 Standen Ltd. Electrodes for applying an electric field in-vivo over an extended period of time
US9089691B2 (en) 2004-12-07 2015-07-28 Cardiac Pacemakers, Inc. Stimulator for auricular branch of vagus nerve
US20070038264A1 (en) 2004-12-21 2007-02-15 Jaax Kristen N Methods and systems for treating autism
DE602005025020D1 (de) 2004-12-27 2011-01-05 The Feinstein Inst Medical Res Behandlung von entzündlichen erkrankungen durch el
US20070276449A1 (en) 2005-06-15 2007-11-29 Med-Lectric Corporation Interactive transcutaneous electrical nerve stimulation device
US8660647B2 (en) 2005-07-28 2014-02-25 Cyberonics, Inc. Stimulating cranial nerve to treat pulmonary disorder
US7555344B2 (en) 2005-10-28 2009-06-30 Cyberonics, Inc. Selective neurostimulation for treating epilepsy
US8676330B2 (en) 2009-03-20 2014-03-18 ElectroCore, LLC Electrical and magnetic stimulators used to treat migraine/sinus headache and comorbid disorders
US9037247B2 (en) 2005-11-10 2015-05-19 ElectroCore, LLC Non-invasive treatment of bronchial constriction
US20110125203A1 (en) * 2009-03-20 2011-05-26 ElectroCore, LLC. Magnetic Stimulation Devices and Methods of Therapy
US8812112B2 (en) 2005-11-10 2014-08-19 ElectroCore, LLC Electrical treatment of bronchial constriction
US8874227B2 (en) * 2009-03-20 2014-10-28 ElectroCore, LLC Devices and methods for non-invasive capacitive electrical stimulation and their use for vagus nerve stimulation on the neck of a patient
US8868177B2 (en) 2009-03-20 2014-10-21 ElectroCore, LLC Non-invasive treatment of neurodegenerative diseases
US7747324B2 (en) * 2005-11-10 2010-06-29 Electrocore Llc Electrical stimulation treatment of bronchial constriction
US20090234417A1 (en) * 2005-11-10 2009-09-17 Electrocore, Inc. Methods And Apparatus For The Treatment Of Metabolic Disorders
US8262556B2 (en) 2005-12-19 2012-09-11 Neuralieve, Inc. Magnetic pulsing system for inducing electric currents in a human body
US7672728B2 (en) 2005-12-28 2010-03-02 Cardiac Pacemakers, Inc. Neural stimulator to treat sleep disordered breathing
US8868172B2 (en) 2005-12-28 2014-10-21 Cyberonics, Inc. Methods and systems for recommending an appropriate action to a patient for managing epilepsy and other neurological disorders
US7660636B2 (en) 2006-01-04 2010-02-09 Accelerated Care Plus Corp. Electrical stimulation device and method for the treatment of dysphagia
US20080051852A1 (en) 2006-01-21 2008-02-28 Cerbomed Gmbh Device and method for the transdermal stimulation of a nerve of the human body
US7711430B2 (en) * 2006-02-10 2010-05-04 Electrocore Llc Methods and apparatus for treating anaphylaxis using electrical modulation
US20100241188A1 (en) 2009-03-20 2010-09-23 Electrocore, Inc. Percutaneous Electrical Treatment Of Tissue
EP2010283A2 (en) 2006-04-27 2009-01-07 Eyad Kishawi Device and method for non-invasive, localized neural stimulation utilizing hall effect phenomenon
US7869885B2 (en) 2006-04-28 2011-01-11 Cyberonics, Inc Threshold optimization for tissue stimulation therapy
DE102006023824B4 (de) 2006-05-20 2010-01-28 Cerbomed Gmbh Vorrichtung zur transkutanen Aufbringung eines Reizes oder zur transkutanen Erfassung eines Parameters
US9630003B2 (en) 2006-06-15 2017-04-25 Htk Enterprises, Inc. Non-invasive neuro stimulation system
US20080097549A1 (en) * 2006-09-01 2008-04-24 Colbaugh Michael E Electrode Assembly and Method of Using Same
CA2665134A1 (en) 2006-10-02 2008-04-10 Emkinetics, Inc. Method and apparatus for magnetic induction therapy
US7797041B2 (en) 2006-10-11 2010-09-14 Cardiac Pacemakers, Inc. Transcutaneous neurostimulator for modulating cardiovascular function
US20080132966A1 (en) * 2006-12-05 2008-06-05 G&L Consulting, Llc Stimulation of coronary artery baroreceptors
US8301239B2 (en) 2007-01-18 2012-10-30 Cardiac Pacemakers, Inc. Systems, devices and methods for acute autonomic stimulation
US7949403B2 (en) * 2007-02-27 2011-05-24 Accelerated Care Plus Corp. Electrical stimulation device and method for the treatment of neurological disorders
EP2136872A4 (en) * 2007-04-13 2010-05-12 Alejandro Covalin DEVICE AND METHOD FOR THE TREATMENT OF HEADACHE
US7869884B2 (en) 2007-04-26 2011-01-11 Cyberonics, Inc. Non-surgical device and methods for trans-esophageal vagus nerve stimulation
US8755892B2 (en) 2007-05-16 2014-06-17 Cardiac Pacemakers, Inc. Systems for stimulating neural targets
WO2009018518A1 (en) * 2007-08-02 2009-02-05 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Methods and systems for achieving a physiological response by pudendal nerve stimulation and bockade
AU2008283857A1 (en) 2007-08-06 2009-02-12 Great Lakes Biosciences, Llc Methods and apparatus for electrical stimulation of tissues using signals that minimize the effects of tissue impedance
US8260439B2 (en) * 2007-11-16 2012-09-04 Ethicon, Inc. Nerve stimulation patches and methods for stimulating selected nerves
US8170683B2 (en) * 2007-12-14 2012-05-01 Ethicon, Inc. Dermatome stimulation devices and methods
JP2009233024A (ja) 2008-03-26 2009-10-15 Terumo Corp 迷走神経刺激システム
EP2116275A1 (en) 2008-05-09 2009-11-11 Eumedic Limited A plurality of electrons for use in the restoration of a patient's health
MX2010012372A (es) 2008-05-13 2011-02-22 Cerbomed Gmbh Metodo para mejorar la operacion del tejido neutral.
US8914122B2 (en) 2009-03-20 2014-12-16 ElectroCore, LLC Devices and methods for non-invasive capacitive electrical stimulation and their use for vagus nerve stimulation on the neck of a patient
US20100286553A1 (en) 2009-05-08 2010-11-11 Feler Claudio A Devices and Methods for Screening of Vagal Nerve Stimulation
US8483832B2 (en) * 2009-05-20 2013-07-09 ElectroCore, LLC Systems and methods for selectively applying electrical energy to tissue

Also Published As

Publication number Publication date
US20110276112A1 (en) 2011-11-10
US9242092B2 (en) 2016-01-26
EP2686060B1 (en) 2020-02-26
AU2021200212A1 (en) 2021-03-18
EP2962725A1 (en) 2016-01-06
JP2024070862A (ja) 2024-05-23
JP2019177141A (ja) 2019-10-17
IL227868B (en) 2019-02-28
AU2020204156A1 (en) 2020-07-09
BR112013023021A2 (pt) 2016-12-06
US20150297889A1 (en) 2015-10-22
IL227868A0 (en) 2013-09-30
EP2962724A1 (en) 2016-01-06
JP7714070B2 (ja) 2025-07-28
CA2826835A1 (en) 2012-09-13
EP2962725B1 (en) 2021-06-16
JP2017080490A (ja) 2017-05-18
AU2021200212B2 (en) 2022-11-03
CA2826835C (en) 2016-10-11
US8874227B2 (en) 2014-10-28
US9067054B2 (en) 2015-06-30
JP2022009757A (ja) 2022-01-14
EP2962724B8 (en) 2021-03-24
AU2019201050B2 (en) 2020-03-26
US20140236272A1 (en) 2014-08-21
WO2012121750A1 (en) 2012-09-13
JP7518809B2 (ja) 2024-07-18
EP3666325A1 (en) 2020-06-17
EP2962724B1 (en) 2021-01-20
AU2019201050A1 (en) 2019-03-07
CN103517732A (zh) 2014-01-15
US9717904B2 (en) 2017-08-01
US20160136423A1 (en) 2016-05-19
EP3666325B1 (en) 2023-10-11
AU2011361696A1 (en) 2013-08-29
EP2686060A1 (en) 2014-01-22
JP2014510586A (ja) 2014-05-01
CN103517732B (zh) 2016-09-07
MX2013010215A (es) 2014-04-25
BR112013023021B1 (pt) 2022-04-05
JP6970704B2 (ja) 2021-11-24
AU2020204156B2 (en) 2020-10-15
AU2011361696B2 (en) 2018-11-15
EP2686060A4 (en) 2014-08-27

Similar Documents

Publication Publication Date Title
MX351494B (es) Dispositivos y métodos para la estimulación eléctrica capacitiva no invasiva y su uso para la estimulación del nervio vago en el cuello de un paciente.
Golberg et al. Towards electroporation based treatment planning considering electric field induced muscle contractions
US9242085B2 (en) Transcutaneous electrical stimulation for treating neurological disorders
US20120259390A1 (en) Wearable Photvoltaic Ultra-Low frequency Acupoint Stimulator
AU2015219295B2 (en) Transcranial electrostimulation device and method
CN110893261A (zh) 具有降低能量的交错多触点神经调制治疗
Krenn et al. Selectivity of transcutaneous stimulation of lumbar posterior roots at different spinal levels in humans
WO2014168957A3 (en) Noninvasive or percutaneous nerve stimulation
JP2012506759A5 (es)
US20110172735A1 (en) Systems and methods for therapy
WO2011139623A3 (en) System and method for stimulating sensory nerves
US20100191316A1 (en) Electrode set and stimulating device
JP2014510586A5 (es)
MX2009001234A (es) Dispositivo para estimulacion y registro bipolar con electrodos ampliamente separados.
DE602004029822D1 (de) Mrt-sicheres implantierbares medizinprodukt
RU2014100956A (ru) Устройство и способ для улучшения кожи, используя ra-эффект или ra плюс-эффект
WO2004064915A3 (en) Spinal cord stimulation with interferential current
JP2013525017A5 (es)
NZ711655A (en) Implantable electroacupuncture device employing a high impedance coin-cell battery as a primary power source
EP3848090A3 (en) Acupoint stimulation device and acupoint stimulation method using the same
MX2017009822A (es) Aparato de estimulacion electrica venosa y sus metodos y usos.
JP2015047363A (ja) 電気刺激装置
CN106110501A (zh) 经皮神经电刺激电极针、经皮神经电刺激装置
ES2661188T3 (es) Regulador del ritmo cardíaco temporal no invasivo interferencial
GB201208727D0 (en) Treatment or therapeutic apparatus

Legal Events

Date Code Title Description
FG Grant or registration