MX340571B - Capsula que se desintegra especificamente en el intestino grueso. - Google Patents
Capsula que se desintegra especificamente en el intestino grueso.Info
- Publication number
- MX340571B MX340571B MX2014011760A MX2014011760A MX340571B MX 340571 B MX340571 B MX 340571B MX 2014011760 A MX2014011760 A MX 2014011760A MX 2014011760 A MX2014011760 A MX 2014011760A MX 340571 B MX340571 B MX 340571B
- Authority
- MX
- Mexico
- Prior art keywords
- capsule
- coating film
- intestine
- disintegrable
- disintegrated
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/745—Bifidobacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/40—Transferrins, e.g. lactoferrins, ovotransferrins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/482—Serine endopeptidases (3.4.21)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21062—Subtilisin (3.4.21.62)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- General Preparation And Processing Of Foods (AREA)
Abstract
La presente invención es para obtener cápsulas que no se desintegren en el estómago ni en el intestino delgado después de administrarlas oralmente y que se desintegren específicamente en el intestino grueso; la presente invención así proporciona una cápsula que se desintegra específicamente en el intestino grueso, que comprende un contenido que comprende un agente principal y una carcasa que cubre el contenido y que comprende un polímero natural soluble en agua como material base de carcasa y quitosano en polvo que se dispersa en el polímero natural soluble en agua.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2012078529A JP5102401B1 (ja) | 2012-03-30 | 2012-03-30 | 大腸特異崩壊性カプセル |
PCT/JP2012/074412 WO2013145379A1 (ja) | 2012-03-30 | 2012-09-24 | 大腸特異崩壊性カプセル |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2014011760A MX2014011760A (es) | 2015-03-05 |
MX340571B true MX340571B (es) | 2016-07-13 |
Family
ID=47528495
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2014011760A MX340571B (es) | 2012-03-30 | 2012-09-24 | Capsula que se desintegra especificamente en el intestino grueso. |
Country Status (19)
Country | Link |
---|---|
US (1) | US8747893B2 (es) |
EP (1) | EP2832352B1 (es) |
JP (1) | JP5102401B1 (es) |
KR (1) | KR101547791B1 (es) |
CN (1) | CN104321052B (es) |
AU (1) | AU2012374707B2 (es) |
BR (1) | BR112014024316B1 (es) |
CA (1) | CA2868592C (es) |
DK (1) | DK2832352T3 (es) |
ES (1) | ES2622295T3 (es) |
HU (1) | HUE033527T2 (es) |
MX (1) | MX340571B (es) |
MY (1) | MY170969A (es) |
PH (1) | PH12014502191B1 (es) |
PL (1) | PL2832352T3 (es) |
PT (1) | PT2832352T (es) |
SG (1) | SG11201406052XA (es) |
TW (1) | TWI508754B (es) |
WO (1) | WO2013145379A1 (es) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104968356A (zh) * | 2012-12-21 | 2015-10-07 | 日清药业股份有限公司 | 大肠输送胶囊及其制备方法 |
US10272036B2 (en) * | 2013-12-06 | 2019-04-30 | Intervet Inc. | Composition for oral delivery of bioactive agents |
PL3191083T3 (pl) | 2014-09-11 | 2021-07-12 | Gelita Ag | Cząstki żelatyny/pektyny |
EP3205339B1 (en) * | 2014-10-06 | 2022-08-03 | Fuji Capsule Co., Ltd. | Method of manufacturing enteric seamless soft capsule |
JP5989953B1 (ja) * | 2015-12-28 | 2016-09-07 | 森下仁丹株式会社 | 粉末状成分含有シームレスカプセルおよびその製造方法 |
JP6457963B2 (ja) * | 2016-02-25 | 2019-01-23 | 日清ファルマ株式会社 | 大腸デリバリーカプセル製剤 |
JP6250211B1 (ja) * | 2017-01-17 | 2017-12-20 | 森下仁丹株式会社 | 水含有カプセル、並びに水含有カプセルの製造方法 |
EP3741368B1 (en) * | 2018-01-18 | 2024-03-06 | Keio University | Capsule for use in treating ulcerative colitis |
US11980691B2 (en) | 2018-03-15 | 2024-05-14 | R.P. Scherer Technologies, Llc | Enteric softgel capsules |
AU2020370053A1 (en) | 2019-10-21 | 2022-04-21 | Soane Pharma LLC | Orally ingestible delivery system |
Family Cites Families (43)
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JPS518176A (ja) | 1974-07-11 | 1976-01-22 | Morishita Jintan Co | Tsugimenashitankakunijukapuserunoseizohohotokono hohoo jitsushisurutameno seizosochi |
JPS60172343A (ja) | 1984-02-15 | 1985-09-05 | Akira Horikawa | 多重マイクロカプセルの製造法およびその装置 |
JP2587219B2 (ja) * | 1986-06-10 | 1997-03-05 | エーザイ株式会社 | 溶解遅延性のゼラチン製剤組成物 |
JPH0813748B2 (ja) | 1990-04-23 | 1996-02-14 | 帝國製薬株式会社 | 大腸崩壊性ポリペプチド系経口製剤 |
JPH064531B2 (ja) | 1990-06-04 | 1994-01-19 | アイセロ化学株式会社 | 大腸崩壊性硬質カプセル |
JP3181062B2 (ja) * | 1991-01-31 | 2001-07-03 | 帝國製薬株式会社 | 下部消化管崩壊経口製剤 |
JP3592723B2 (ja) * | 1991-02-19 | 2004-11-24 | 帝國製薬株式会社 | 非崩壊・持続性カプセル製剤 |
JP2916290B2 (ja) * | 1991-03-22 | 1999-07-05 | 帝國製薬株式会社 | 生理活性ポリペプチド含有大腸崩壊経口製剤 |
US5364634A (en) * | 1991-11-08 | 1994-11-15 | Southwest Research Institute | Controlled-release PH sensitive capsule and adhesive system and method |
US5252581A (en) | 1992-07-20 | 1993-10-12 | Hoechst-Roussel Pharmaceuticals Inc. | Substituted aminothienopyridines, pharmaceutical composition and use |
DK0616802T3 (da) * | 1992-08-13 | 1998-10-19 | Teikoku Seiyaku Kk | Oralt præparat til frigivelse i de nedre fordøjelseskanaler |
JP2555520B2 (ja) | 1992-12-14 | 1996-11-20 | アイセロ化学株式会社 | キトサン硬カプセルおよびその製造法 |
JP2521229B2 (ja) | 1993-06-17 | 1996-08-07 | アイセロ化学株式会社 | 大腸崩壊性組成物及びその製造法 |
JPH072650A (ja) | 1993-06-18 | 1995-01-06 | Tanabe Seiyaku Co Ltd | 放出部位制御型製剤 |
JPH0710745A (ja) | 1993-06-22 | 1995-01-13 | Tanabe Seiyaku Co Ltd | 放出開始時間制御型腸デリバリー経口製剤 |
CA2127392C (en) | 1993-07-08 | 2008-05-27 | Hideki Sunohara | Process for producing capsule and capsule obtained thereby |
JP3102990B2 (ja) * | 1993-07-08 | 2000-10-23 | 森下仁丹株式会社 | カプセルの製造方法およびそれから得られたカプセル |
JP3022273B2 (ja) | 1995-08-23 | 2000-03-15 | 住友金属工業株式会社 | 連続焼鈍設備における冷延鋼帯の洗浄方法および装置 |
US6248362B1 (en) | 1997-03-26 | 2001-06-19 | Meiji Seika Kaisha, Ltd. | Large intestinal delivery composite |
JPH10324642A (ja) | 1997-03-26 | 1998-12-08 | Meiji Seika Kaisha Ltd | 大腸送達性構造体 |
CA2376261A1 (en) * | 1999-06-09 | 2000-12-14 | Mochida Pharmaceutical Co., Ltd. | System for release in lower gastrointestinal tract |
US6340473B1 (en) * | 1999-07-07 | 2002-01-22 | R.P. Scherer Technologies, Inc. | Film forming compositions comprising modified starches and iota-carrageenan and methods for manufacturing soft capsules using same |
WO2001010467A1 (fr) * | 1999-08-09 | 2001-02-15 | Dainippon Pharmaceutical Co., Ltd. | Preparations solides contenant de la poudre de chitosane et procede de production associe |
JP4524009B2 (ja) | 1999-08-09 | 2010-08-11 | 大日本住友製薬株式会社 | 大腸内放出性カプセル製剤 |
JP4169894B2 (ja) * | 1999-12-24 | 2008-10-22 | 株式会社三協 | ソフトカプセルの製造方法 |
CN1141974C (zh) * | 2000-06-07 | 2004-03-17 | 张昊 | 结肠定位释放的口服生物制剂 |
CN1285333C (zh) * | 2000-06-07 | 2006-11-22 | 张昊 | 结肠定位释放的口服制剂及其制备方法 |
JP4614258B2 (ja) * | 2001-06-12 | 2011-01-19 | 森下仁丹株式会社 | 崩壊性が改良されたソフトカプセル |
US7670612B2 (en) * | 2002-04-10 | 2010-03-02 | Innercap Technologies, Inc. | Multi-phase, multi-compartment capsular delivery apparatus and methods for using same |
US6974592B2 (en) * | 2002-04-11 | 2005-12-13 | Ocean Nutrition Canada Limited | Encapsulated agglomeration of microcapsules and method for the preparation thereof |
US7670624B2 (en) * | 2004-01-29 | 2010-03-02 | Astella Pharma Inc. | Gastrointestinal-specific multiple drug release system |
EP1727525A4 (en) * | 2004-03-23 | 2009-12-09 | Lytone Enterprise Inc | CAPSULE CONTAINING CHITOSANE NOYE OR ENCAPSULE |
WO2006016595A1 (ja) * | 2004-08-10 | 2006-02-16 | Nrl Pharma, Inc. | ラクトフェリン複合体及びその製造方法 |
EP1848729A2 (en) * | 2005-01-27 | 2007-10-31 | Ocean Nutrition Canada Limited | Chromium-fatty acid compounds and methods of making and using thereof |
KR101430018B1 (ko) * | 2005-06-21 | 2014-08-14 | 브이. 만느 피스 | 젤란으로 된 파쇄성 심리스 캡슐 및 그 제조방법 |
US9968120B2 (en) * | 2006-05-17 | 2018-05-15 | Dsm Nutritional Products Ag | Homogenized formulations containing microcapsules and methods of making and using thereof |
US20070034827A1 (en) * | 2005-12-02 | 2007-02-15 | Zhixin Li | Blends of gelling and non-gelling starches with gellan gums and plasticizer |
US20070128285A1 (en) * | 2005-07-12 | 2007-06-07 | Chikara Jin | Pharmaceutical composition for oral administration |
KR101007865B1 (ko) * | 2007-06-18 | 2011-01-14 | 연세대학교 산학협력단 | 키토산 및 피틴산을 포함하는 서방성 키토산 캡슐 |
US8715705B2 (en) * | 2009-07-29 | 2014-05-06 | Covidien Lp | Multilayer medical devices having an encapsulated edge and methods thereof |
JP5496616B2 (ja) | 2009-11-18 | 2014-05-21 | フロイント産業株式会社 | 大腸ドラッグデリバリーシステム製剤 |
JP5087167B2 (ja) * | 2010-12-28 | 2012-11-28 | フロイント産業株式会社 | ビフィズス菌大腸デリバリーカプセル及びその製造方法 |
US20120301546A1 (en) * | 2011-05-26 | 2012-11-29 | Hassan Emadeldin M | Acid-resistant soft gel compositions |
-
2012
- 2012-03-30 JP JP2012078529A patent/JP5102401B1/ja active Active
- 2012-09-24 ES ES12872930.8T patent/ES2622295T3/es active Active
- 2012-09-24 MX MX2014011760A patent/MX340571B/es active IP Right Grant
- 2012-09-24 CA CA2868592A patent/CA2868592C/en active Active
- 2012-09-24 KR KR1020147030343A patent/KR101547791B1/ko active IP Right Grant
- 2012-09-24 BR BR112014024316-6A patent/BR112014024316B1/pt active IP Right Grant
- 2012-09-24 CN CN201280073538.4A patent/CN104321052B/zh active Active
- 2012-09-24 HU HUE12872930A patent/HUE033527T2/en unknown
- 2012-09-24 PL PL12872930T patent/PL2832352T3/pl unknown
- 2012-09-24 DK DK12872930.8T patent/DK2832352T3/en active
- 2012-09-24 MY MYPI2014702816A patent/MY170969A/en unknown
- 2012-09-24 AU AU2012374707A patent/AU2012374707B2/en active Active
- 2012-09-24 WO PCT/JP2012/074412 patent/WO2013145379A1/ja active Application Filing
- 2012-09-24 PT PT128729308T patent/PT2832352T/pt unknown
- 2012-09-24 EP EP12872930.8A patent/EP2832352B1/en active Active
- 2012-09-24 SG SG11201406052XA patent/SG11201406052XA/en unknown
- 2012-10-03 TW TW101136531A patent/TWI508754B/zh active
- 2012-10-16 US US13/652,543 patent/US8747893B2/en active Active
-
2014
- 2014-09-29 PH PH12014502191A patent/PH12014502191B1/en unknown
Also Published As
Publication number | Publication date |
---|---|
PH12014502191A1 (en) | 2014-12-10 |
HUE033527T2 (en) | 2017-12-28 |
EP2832352B1 (en) | 2017-03-29 |
AU2012374707A1 (en) | 2014-10-16 |
MX2014011760A (es) | 2015-03-05 |
AU2012374707B2 (en) | 2015-04-09 |
PT2832352T (pt) | 2017-05-31 |
BR112014024316A8 (pt) | 2018-01-23 |
WO2013145379A1 (ja) | 2013-10-03 |
CA2868592C (en) | 2015-09-22 |
CA2868592A1 (en) | 2013-10-03 |
EP2832352A4 (en) | 2015-04-22 |
MY170969A (en) | 2019-09-23 |
CN104321052A (zh) | 2015-01-28 |
US8747893B2 (en) | 2014-06-10 |
CN104321052B (zh) | 2016-08-17 |
JP2013209297A (ja) | 2013-10-10 |
KR101547791B1 (ko) | 2015-08-26 |
US20130259933A1 (en) | 2013-10-03 |
ES2622295T3 (es) | 2017-07-06 |
KR20140139606A (ko) | 2014-12-05 |
PL2832352T3 (pl) | 2017-08-31 |
PH12014502191B1 (en) | 2014-12-10 |
EP2832352A1 (en) | 2015-02-04 |
TWI508754B (zh) | 2015-11-21 |
TW201338809A (zh) | 2013-10-01 |
DK2832352T3 (en) | 2017-07-10 |
BR112014024316B1 (pt) | 2022-05-31 |
JP5102401B1 (ja) | 2012-12-19 |
SG11201406052XA (en) | 2014-11-27 |
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Legal Events
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