MX337535B - Anticuerpo, kit y metodo para la determinacion de peptidos amiloides. - Google Patents

Anticuerpo, kit y metodo para la determinacion de peptidos amiloides.

Info

Publication number
MX337535B
MX337535B MX2013011515A MX2013011515A MX337535B MX 337535 B MX337535 B MX 337535B MX 2013011515 A MX2013011515 A MX 2013011515A MX 2013011515 A MX2013011515 A MX 2013011515A MX 337535 B MX337535 B MX 337535B
Authority
MX
Mexico
Prior art keywords
antibody
kit
amyloid peptides
determining amyloid
determining
Prior art date
Application number
MX2013011515A
Other languages
English (en)
Other versions
MX2013011515A (es
Inventor
Barrio Manuel Sarasa
Original Assignee
Araclon Biotech Sl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Araclon Biotech Sl filed Critical Araclon Biotech Sl
Publication of MX2013011515A publication Critical patent/MX2013011515A/es
Publication of MX337535B publication Critical patent/MX337535B/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4709—Amyloid plaque core protein
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G01N2800/2814—Dementia; Cognitive disorders
    • G01N2800/2821—Alzheimer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/56—Staging of a disease; Further complications associated with the disease

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La presente invención se refiere al campo de los inmunoensayos que permiten la detección de péptidos Aß17 en virtud del uso de un anticuerpo anti-Aß17 y un kit y un método que usan dicho anticuerpo. La invención también se refiere a un método para diagnosticar o distinguir entre diferentes fases de una enfermedad neurodegenerativa.
MX2013011515A 2011-04-12 2012-04-03 Anticuerpo, kit y metodo para la determinacion de peptidos amiloides. MX337535B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP11382107A EP2511296A1 (en) 2011-04-12 2011-04-12 Antibody, kit and method for determination of amyloid peptides
PCT/ES2012/070231 WO2012140296A1 (es) 2011-04-12 2012-04-03 Anticuerpo, kit y metodo para la determinacion de peptidos amiloides

Publications (2)

Publication Number Publication Date
MX2013011515A MX2013011515A (es) 2014-01-08
MX337535B true MX337535B (es) 2016-03-09

Family

ID=44510162

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013011515A MX337535B (es) 2011-04-12 2012-04-03 Anticuerpo, kit y metodo para la determinacion de peptidos amiloides.

Country Status (18)

Country Link
US (2) US9255932B2 (es)
EP (2) EP2511296A1 (es)
JP (1) JP5926368B2 (es)
KR (1) KR101602546B1 (es)
CN (1) CN103547593B (es)
AR (1) AR085959A1 (es)
BR (1) BR112013023540A2 (es)
CA (1) CA2828307C (es)
CL (1) CL2013002586A1 (es)
ES (1) ES2667016T3 (es)
IL (2) IL228170B (es)
MX (1) MX337535B (es)
MY (1) MY161291A (es)
RU (1) RU2571213C2 (es)
SG (1) SG194053A1 (es)
TW (1) TWI549966B (es)
WO (1) WO2012140296A1 (es)
ZA (1) ZA201306572B (es)

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CN103852579B (zh) * 2012-12-05 2018-02-23 姚钧 一种人体血清Aβ的定量检测方法
WO2014160647A1 (en) * 2013-03-24 2014-10-02 The Washington University Method for amyloid beta sample processing
MX2016006584A (es) * 2013-11-20 2016-09-06 Univ Iowa Res Found Métodos y composiciones para tratar los depósitos de amiloide.
BR112017006419A2 (pt) 2014-09-30 2017-12-19 Univ Washington medições cinéticas de tau
US10759837B2 (en) 2015-11-09 2020-09-01 The University Of British Columbia Anti-amyloid beta antibodies binding to a cyclic amyloid beta peptide
US10774120B2 (en) 2015-11-09 2020-09-15 The University Of British Columbia Anti-amyloid beta antibodies binding to a cyclic amyloid beta peptide
US20200166507A1 (en) * 2016-02-15 2020-05-28 Nobelpharma Co., Ltd. Measurement method and measurement kit for proteins related to genetic diseases
CA3031135A1 (en) 2016-07-18 2018-01-25 The University Of British Columbia Antibodies to amyloid beta
TW201827467A (zh) 2016-11-03 2018-08-01 比利時商健生藥品公司 焦穀胺酸類澱粉蛋白－β之抗體及其用途
US20180125920A1 (en) 2016-11-09 2018-05-10 The University Of British Columbia Methods for preventing and treating A-beta oligomer-associated and/or -induced diseases and conditions
US11397188B2 (en) * 2017-03-30 2022-07-26 Board Of Regents, The University Of Texas System Method of detecting an APP Alzheimer's disease marker peptide in patients with Alzheimer's disease
KR20200038298A (ko) * 2017-08-18 2020-04-10 더 존스 홉킨스 유니버시티 단백질 정제를 위한 초분자 필라멘트 조립체
RU2708465C1 (ru) * 2019-02-18 2019-12-09 Федеральное Государственное Бюджетное Учреждение Науки Институт Молекулярной Биологии Им. В.А. Энгельгардта Российской Академии Наук (Имб Ран) Способ детекции модификаций амилоидного пептида с помощью высокоспецифичных антител
SG11202110504XA (en) 2019-03-26 2021-10-28 Janssen Pharmaceutica Nv ANTIBODIES TO PYROGLUTAMATE AMYLOID-ß AND USES THEREOF
US20220260592A1 (en) * 2019-05-10 2022-08-18 Quest Diagnostics Investments Llc MULTIPLEX ASSAY FOR DETERMINING THE ß-AMYLOID 42/40 RATIO IN HUMAN PLASMA SPECIMENS
WO2021009074A1 (en) 2019-07-12 2021-01-21 Adx Neurosciences Nv Novel markers as early predictors of alzheimer's pathology
CN111334480B (zh) * 2020-05-18 2020-09-01 苏州仁端生物医药科技有限公司 一种分泌抗Aβ1-42单克隆抗体的杂交瘤细胞株及其应用
JP7478040B2 (ja) * 2020-06-25 2024-05-02 シスメックス株式会社 Ａβペプチドの測定方法及びその方法に用いられる試薬組成物
CN118382636A (zh) * 2021-12-17 2024-07-23 豪夫迈·罗氏有限公司 一种用于检测淀粉样蛋白β42(Aβ42)的新抗体
WO2024087430A1 (zh) * 2023-02-28 2024-05-02 湖南乾康科技有限公司 一种用于定量检测尿液淀粉样前体蛋白片段的酶联免疫检测方法
CN116574271B (zh) * 2023-06-06 2023-12-19 苏州谱迪生物科技有限公司 一种用于免疫检测低丰度生物标志物信号级联放大的荧光树状大分子的制备方法及其应用

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Also Published As

Publication number Publication date
TWI549966B (zh) 2016-09-21
MX2013011515A (es) 2014-01-08
US9863961B2 (en) 2018-01-09
IL253794A0 (en) 2017-09-28
EP2698381A4 (en) 2015-04-01
EP2511296A1 (en) 2012-10-17
RU2571213C2 (ru) 2015-12-20
SG194053A1 (en) 2013-11-29
US9255932B2 (en) 2016-02-09
TW201305201A (zh) 2013-02-01
CN103547593B (zh) 2016-04-20
RU2013139450A (ru) 2015-03-10
CA2828307A1 (en) 2012-10-18
AR085959A1 (es) 2013-11-06
WO2012140296A1 (es) 2012-10-18
EP2698381B1 (en) 2018-01-24
CN103547593A (zh) 2014-01-29
CA2828307C (en) 2019-06-11
BR112013023540A2 (pt) 2016-11-22
JP2014516357A (ja) 2014-07-10
JP5926368B2 (ja) 2016-05-25
NZ615011A (en) 2015-11-27
US20140024054A1 (en) 2014-01-23
US20160195548A1 (en) 2016-07-07
ES2667016T3 (es) 2018-05-09
KR101602546B1 (ko) 2016-03-10
IL228170B (en) 2018-01-31
EP2698381A1 (en) 2014-02-19
CL2013002586A1 (es) 2014-05-16
WO2012140296A9 (es) 2013-08-29
ZA201306572B (en) 2017-11-29
KR20130135931A (ko) 2013-12-11
MY161291A (en) 2017-04-14

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