WO2012175602A3 - Elisa for calprotectin - Google Patents

Elisa for calprotectin Download PDF

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Publication number
WO2012175602A3
WO2012175602A3 PCT/EP2012/061948 EP2012061948W WO2012175602A3 WO 2012175602 A3 WO2012175602 A3 WO 2012175602A3 EP 2012061948 W EP2012061948 W EP 2012061948W WO 2012175602 A3 WO2012175602 A3 WO 2012175602A3
Authority
WO
WIPO (PCT)
Prior art keywords
calprotectin
elisa
provides
quantification
monoclonal antibody
Prior art date
Application number
PCT/EP2012/061948
Other languages
French (fr)
Other versions
WO2012175602A2 (en
Inventor
Magne FAGERHOL
Original Assignee
Calpro As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Calpro As filed Critical Calpro As
Publication of WO2012175602A2 publication Critical patent/WO2012175602A2/en
Publication of WO2012175602A3 publication Critical patent/WO2012175602A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4727—Calcium binding proteins, e.g. calmodulin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

The present invention provides an improved method for the immunological detection and quantification of calprotectin, based on a monoclonal antibody. The invention further provides a method for selecting antibodies that react adequately with calprotectin in stool extracts.
PCT/EP2012/061948 2011-06-21 2012-06-21 Elisa for calprotectin WO2012175602A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NO20110896 2011-06-21
NO20110896A NO336551B1 (en) 2011-06-21 2011-06-21 Improved ELISA for calprotectin in faecal or gastrointestinal tract test

Publications (2)

Publication Number Publication Date
WO2012175602A2 WO2012175602A2 (en) 2012-12-27
WO2012175602A3 true WO2012175602A3 (en) 2013-06-13

Family

ID=46331308

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2012/061948 WO2012175602A2 (en) 2011-06-21 2012-06-21 Elisa for calprotectin

Country Status (2)

Country Link
NO (1) NO336551B1 (en)
WO (1) WO2012175602A2 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013132347A2 (en) * 2012-03-06 2013-09-12 Calpro As Improved elisa immunoassay for calprotectin
EP3248015A1 (en) * 2015-01-23 2017-11-29 Westfälische Wilhelms-Universität Münster Compounds and methods for the detection of calprotectin
CA2998349A1 (en) 2015-09-17 2017-03-23 Amgen Inc. Prediction of clinical response to il23-antagonists using il23 pathway biomarkers
KR20180096633A (en) 2015-12-22 2018-08-29 암젠 인크 CCL20 as a predictor of clinical response to IL23-antagonists
EP3487874A1 (en) 2016-07-20 2019-05-29 Westfälische Wilhelms-Universität Münster Complex-specific standardization of immunological methods for the quantification of s100a12
CN110609143A (en) * 2019-10-31 2019-12-24 苏州普瑞森基因科技有限公司 Calprotectin heterodimer detection kit and application thereof
CN114891103B (en) * 2022-06-11 2023-07-07 巴迪泰(青岛)生物科技有限公司 Calprotectin monoclonal antibody and kit
CN117607461A (en) * 2023-12-06 2024-02-27 陕西省动物研究所 Detection method of S100A8 protein and application thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002088181A2 (en) * 2001-04-30 2002-11-07 Switch Biotech Ag Mrp8/mrp14 heterodimer, or its individual components in combination, for treating and/or preventing skin diseases, wounds and/or wound-healing disturbances

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0937259B1 (en) 1996-11-01 2004-10-06 Magne K. Fagerhol Process for the extraction of proteins

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002088181A2 (en) * 2001-04-30 2002-11-07 Switch Biotech Ag Mrp8/mrp14 heterodimer, or its individual components in combination, for treating and/or preventing skin diseases, wounds and/or wound-healing disturbances

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
LUEGERING N ET AL: "Immunohistochemical distribution and serum levels of the Ca2+-binding proteins MRP8, MRP14 and their heterodimeric form MRP8/14 in Crohn's disease", DIGESTION, S. KARGER AG., BASEL, CH, vol. 56, no. 5, 1 January 1995 (1995-01-01), pages 406 - 414, XP009019238, ISSN: 0012-2823, DOI: 10.1159/000201267 *
ROSETH A G ET AL: "ASSESSMENT OF THE NEUTROPHIL DOMINATING PROTEIN CALPROTECTIN IN FECES A METHODOLOGIC STUDY", SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, INFORMA HEALTHCARE, GB, vol. 27, no. 9, 1 January 1992 (1992-01-01), pages 793 - 798, XP009110340, ISSN: 0036-5521, DOI: 10.3109/00365529209011186 *

Also Published As

Publication number Publication date
NO20110896A1 (en) 2012-12-24
NO336551B1 (en) 2015-09-28
WO2012175602A2 (en) 2012-12-27

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