MX2023004052A - Constructos de acido nucleico para transcripcion de arn asociado a un virus (arn va). - Google Patents
Constructos de acido nucleico para transcripcion de arn asociado a un virus (arn va).Info
- Publication number
- MX2023004052A MX2023004052A MX2023004052A MX2023004052A MX2023004052A MX 2023004052 A MX2023004052 A MX 2023004052A MX 2023004052 A MX2023004052 A MX 2023004052A MX 2023004052 A MX2023004052 A MX 2023004052A MX 2023004052 A MX2023004052 A MX 2023004052A
- Authority
- MX
- Mexico
- Prior art keywords
- nucleic acid
- acid constructs
- rna transcription
- promoter
- type
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0681—Cells of the genital tract; Non-germinal cells from gonads
- C12N5/0682—Cells of the female genital tract, e.g. endometrium; Non-germinal cells from ovaries, e.g. ovarian follicle cells
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14121—Viruses as such, e.g. new isolates, mutants or their genomic sequences
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14123—Virus like particles [VLP]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14141—Use of virus, viral particle or viral elements as a vector
- C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14151—Methods of production or purification of viral material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14151—Methods of production or purification of viral material
- C12N2750/14152—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/008—Vector systems having a special element relevant for transcription cell type or tissue specific enhancer/promoter combination
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Virology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Reproductive Health (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP20202010 | 2020-10-15 | ||
| PCT/EP2021/078269 WO2022079083A1 (en) | 2020-10-15 | 2021-10-13 | Nucleic acid constructs for va rna transcription |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2023004052A true MX2023004052A (es) | 2023-05-03 |
Family
ID=72964437
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2023004052A MX2023004052A (es) | 2020-10-15 | 2021-10-13 | Constructos de acido nucleico para transcripcion de arn asociado a un virus (arn va). |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US12312606B2 (https=) |
| EP (1) | EP4229205B1 (https=) |
| JP (1) | JP2023546116A (https=) |
| KR (1) | KR20230085929A (https=) |
| CN (1) | CN116406425A (https=) |
| AR (1) | AR123777A1 (https=) |
| AU (1) | AU2021360197A1 (https=) |
| CA (1) | CA3197730A1 (https=) |
| ES (1) | ES3035361T3 (https=) |
| HR (1) | HRP20250766T1 (https=) |
| HU (1) | HUE071824T2 (https=) |
| IL (1) | IL302046A (https=) |
| MX (1) | MX2023004052A (https=) |
| PL (1) | PL4229205T3 (https=) |
| TW (1) | TW202223094A (https=) |
| WO (1) | WO2022079083A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4189077A1 (en) | 2020-07-30 | 2023-06-07 | Shape Therapeutics Inc. | Stable cell lines for inducible production of raav virions |
| WO2025217034A1 (en) * | 2024-04-07 | 2025-10-16 | Spark Therapeutics, Inc. | Compositions and methods for the regulation of recombinant adeno-associated virus production |
Family Cites Families (78)
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| WO1994017810A1 (en) | 1993-02-12 | 1994-08-18 | The Wistar Institute Of Anatomy And Biology | Recombinant cytomegalovirus vaccine |
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| US20200332278A1 (en) | 2017-06-16 | 2020-10-22 | Universite De Strasbourg | Methods to generate conditional knock-in models |
| MY207534A (en) | 2017-06-30 | 2025-03-03 | Spark Therapeutics Inc | Aav vector column purification methods |
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| WO2019217483A1 (en) * | 2018-05-07 | 2019-11-14 | Spark Therapeutics, Inc. | Plasmid free aav vector producing cell lines |
| GB201816919D0 (en) | 2018-10-17 | 2018-11-28 | Glaxosmithkline Ip Dev Ltd | Adeno-associated viral vector producer cell lines |
| SG11202106217TA (en) * | 2018-12-21 | 2021-07-29 | Lonza Walkersville Inc | Adeno-associated virus (aav) producer cell line and related methods |
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2021
- 2021-10-13 EP EP21786513.8A patent/EP4229205B1/en active Active
- 2021-10-13 AU AU2021360197A patent/AU2021360197A1/en active Pending
- 2021-10-13 AR ARP210102827A patent/AR123777A1/es unknown
- 2021-10-13 ES ES21786513T patent/ES3035361T3/es active Active
- 2021-10-13 MX MX2023004052A patent/MX2023004052A/es unknown
- 2021-10-13 KR KR1020237016221A patent/KR20230085929A/ko active Pending
- 2021-10-13 HU HUE21786513A patent/HUE071824T2/hu unknown
- 2021-10-13 US US17/500,778 patent/US12312606B2/en active Active
- 2021-10-13 CA CA3197730A patent/CA3197730A1/en active Pending
- 2021-10-13 IL IL302046A patent/IL302046A/en unknown
- 2021-10-13 HR HRP20250766TT patent/HRP20250766T1/hr unknown
- 2021-10-13 PL PL21786513.8T patent/PL4229205T3/pl unknown
- 2021-10-13 JP JP2023523028A patent/JP2023546116A/ja active Pending
- 2021-10-13 CN CN202180069666.0A patent/CN116406425A/zh active Pending
- 2021-10-13 WO PCT/EP2021/078269 patent/WO2022079083A1/en not_active Ceased
- 2021-10-14 TW TW110138078A patent/TW202223094A/zh unknown
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| KR20230085929A (ko) | 2023-06-14 |
| US12312606B2 (en) | 2025-05-27 |
| PL4229205T3 (pl) | 2025-08-18 |
| EP4229205C0 (en) | 2025-05-14 |
| IL302046A (en) | 2023-06-01 |
| TW202223094A (zh) | 2022-06-16 |
| WO2022079083A1 (en) | 2022-04-21 |
| AR123777A1 (es) | 2023-01-11 |
| JP2023546116A (ja) | 2023-11-01 |
| HUE071824T2 (hu) | 2025-09-28 |
| EP4229205A1 (en) | 2023-08-23 |
| CN116406425A (zh) | 2023-07-07 |
| US20220135954A1 (en) | 2022-05-05 |
| AU2021360197A9 (en) | 2023-07-13 |
| US20260103684A1 (en) | 2026-04-16 |
| ES3035361T3 (en) | 2025-09-02 |
| CA3197730A1 (en) | 2022-04-21 |
| EP4229205B1 (en) | 2025-05-14 |
| HRP20250766T1 (hr) | 2025-08-15 |
| AU2021360197A1 (en) | 2023-05-18 |
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