MX2022003895A - Metodos para mejorar la terapia de bloqueo del punto de control inmune mediante la modulacion del microbioma. - Google Patents

Metodos para mejorar la terapia de bloqueo del punto de control inmune mediante la modulacion del microbioma.

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Publication number
MX2022003895A
MX2022003895A MX2022003895A MX2022003895A MX2022003895A MX 2022003895 A MX2022003895 A MX 2022003895A MX 2022003895 A MX2022003895 A MX 2022003895A MX 2022003895 A MX2022003895 A MX 2022003895A MX 2022003895 A MX2022003895 A MX 2022003895A
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Mexico
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microbiome
methods
immune checkpoint
modulating
checkpoint blockade
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MX2022003895A
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English (en)
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Jennifer Wargo
Vancheswaran Gopalakrishnan
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Univ Texas
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Application filed by Univ Texas filed Critical Univ Texas
Publication of MX2022003895A publication Critical patent/MX2022003895A/es

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
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    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
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    • C12N1/20—Bacteria; Culture media therefor
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    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
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    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K2035/11—Medicinal preparations comprising living procariotic cells
    • A61K2035/115—Probiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
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  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
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  • Pharmacology & Pharmacy (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
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Abstract

En la presente se proporcionan métodos y composiciones para el tratamiento del cáncer mediante la modulación del microbioma para mejorar la eficacia del bloqueo del punto de control inmune. El microbioma puede modularse mediante la administración de butirato y/o bacterias productoras de butirato. En la presente también se proporcionan métodos para determinar una respuesta a un inhibidor del punto de control inmune al identificar si un sujeto tiene un perfil microbiano favorable.
MX2022003895A 2016-09-27 2019-03-26 Metodos para mejorar la terapia de bloqueo del punto de control inmune mediante la modulacion del microbioma. MX2022003895A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662400372P 2016-09-27 2016-09-27
US201762508885P 2017-05-19 2017-05-19
US201762557566P 2017-09-12 2017-09-12

Publications (1)

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MX2022003895A true MX2022003895A (es) 2022-04-19

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ID=61760978

Family Applications (2)

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MX2019003447A MX2019003447A (es) 2016-09-27 2017-09-27 Metodos para mejorar la terapia de bloqueo del punto de control inmune mediante la modulacion del microbioma.
MX2022003895A MX2022003895A (es) 2016-09-27 2019-03-26 Metodos para mejorar la terapia de bloqueo del punto de control inmune mediante la modulacion del microbioma.

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US (3) US11395838B2 (es)
EP (1) EP3518946A4 (es)
JP (2) JP2020500151A (es)
KR (2) KR102530297B1 (es)
CN (2) CN110267651B (es)
AU (1) AU2017335732A1 (es)
BR (1) BR112019006041A2 (es)
CA (1) CA3038076A1 (es)
MX (2) MX2019003447A (es)
WO (1) WO2018064165A2 (es)

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