MX2019010034A - Metodo para cultivar celulas eucarionticas. - Google Patents

Metodo para cultivar celulas eucarionticas.

Info

Publication number
MX2019010034A
MX2019010034A MX2019010034A MX2019010034A MX2019010034A MX 2019010034 A MX2019010034 A MX 2019010034A MX 2019010034 A MX2019010034 A MX 2019010034A MX 2019010034 A MX2019010034 A MX 2019010034A MX 2019010034 A MX2019010034 A MX 2019010034A
Authority
MX
Mexico
Prior art keywords
eukaryotic cells
cell culture
culturing eukaryotic
culturing
range
Prior art date
Application number
MX2019010034A
Other languages
English (en)
Inventor
Baskar Dinesh
Hsiung Jenny
Lam Susan Leung Woon-
H Yuk Inn
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of MX2019010034A publication Critical patent/MX2019010034A/es

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/14—Bags
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/28—Constructional details, e.g. recesses, hinges disposable or single use
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/16—Vibrating; Shaking; Tilting
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/10—Perfusion
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/20—Degassing; Venting; Bubble traps
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/26—Means for regulation, monitoring, measurement or control, e.g. flow regulation of pH
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/32—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of substances in solution
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/34—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of gas
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/48—Automatic or computerized control
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Sustainable Development (AREA)
  • Analytical Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Computer Hardware Design (AREA)
  • Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • Cell Biology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Se describe un aparato y método para mantener el pH dentro de un intervalo conducente para el crecimiento celular en un sistema de cultivo celular que contiene bicarbonato sin la adición de base. El método depende de las características de transferencia de gas del sistema de bioreactor para modular la transferencia de CO2 a y del cultivo celular, de tal manera que el pH del cultivo celular puede ser mantenido dentro de un intervalo deseado.
MX2019010034A 2009-07-06 2012-01-05 Metodo para cultivar celulas eucarionticas. MX2019010034A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US22331309P 2009-07-06 2009-07-06

Publications (1)

Publication Number Publication Date
MX2019010034A true MX2019010034A (es) 2019-10-15

Family

ID=43429807

Family Applications (3)

Application Number Title Priority Date Filing Date
MX2014010342A MX367489B (es) 2009-07-06 2010-07-06 Metodo para cultivar celulas eucarionticas.
MX2012000354A MX2012000354A (es) 2009-07-06 2010-07-06 Metodo para cultivar celulas eucarionticas.
MX2019010034A MX2019010034A (es) 2009-07-06 2012-01-05 Metodo para cultivar celulas eucarionticas.

Family Applications Before (2)

Application Number Title Priority Date Filing Date
MX2014010342A MX367489B (es) 2009-07-06 2010-07-06 Metodo para cultivar celulas eucarionticas.
MX2012000354A MX2012000354A (es) 2009-07-06 2010-07-06 Metodo para cultivar celulas eucarionticas.

Country Status (14)

Country Link
US (4) US20120329151A1 (es)
EP (2) EP3643773A1 (es)
JP (2) JP2012531930A (es)
KR (1) KR101838302B1 (es)
CN (2) CN107043703B (es)
AU (4) AU2010270726A1 (es)
BR (1) BR112012000242B1 (es)
CA (2) CA2766902C (es)
ES (1) ES2752874T3 (es)
IL (3) IL217223A0 (es)
MX (3) MX367489B (es)
PL (1) PL2451936T3 (es)
SG (1) SG177555A1 (es)
WO (1) WO2011005773A2 (es)

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Publication number Publication date
JP2016063816A (ja) 2016-04-28
ES2752874T3 (es) 2020-04-06
US20120329151A1 (en) 2012-12-27
EP2451936A2 (en) 2012-05-16
IL217223A0 (en) 2012-02-29
WO2011005773A2 (en) 2011-01-13
CA3118479A1 (en) 2011-01-13
BR112012000242B1 (pt) 2019-07-09
EP2451936B1 (en) 2019-08-28
AU2018250474A1 (en) 2018-11-15
CN107043703A (zh) 2017-08-15
US10894940B2 (en) 2021-01-19
CN102482633A (zh) 2012-05-30
US20190233790A1 (en) 2019-08-01
BR112012000242A2 (pt) 2015-09-08
PL2451936T3 (pl) 2020-02-28
EP3643773A1 (en) 2020-04-29
AU2010270726A1 (en) 2012-02-02
JP6358999B2 (ja) 2018-07-18
CA2766902A1 (en) 2011-01-13
IL242092B (en) 2019-07-31
MX2012000354A (es) 2012-02-01
US11939559B2 (en) 2024-03-26
IL267629A (en) 2019-08-29
SG177555A1 (en) 2012-02-28
KR20120047930A (ko) 2012-05-14
CA2766902C (en) 2021-07-06
AU2016202997A1 (en) 2016-05-26
AU2021200110A1 (en) 2021-03-18
MX367489B (es) 2019-08-23
JP2012531930A (ja) 2012-12-13
KR101838302B1 (ko) 2018-03-13
US20150210971A1 (en) 2015-07-30
CN107043703B (zh) 2020-03-27
AU2018250474B2 (en) 2020-10-15
IL242092A0 (en) 2015-11-30
US10190084B2 (en) 2019-01-29
US20210130759A1 (en) 2021-05-06
WO2011005773A3 (en) 2012-01-26

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