MX2017006408A - Linfocitos t gamma delta modificados geneticamente. - Google Patents
Linfocitos t gamma delta modificados geneticamente.Info
- Publication number
- MX2017006408A MX2017006408A MX2017006408A MX2017006408A MX2017006408A MX 2017006408 A MX2017006408 A MX 2017006408A MX 2017006408 A MX2017006408 A MX 2017006408A MX 2017006408 A MX2017006408 A MX 2017006408A MX 2017006408 A MX2017006408 A MX 2017006408A
- Authority
- MX
- Mexico
- Prior art keywords
- genetically modified
- cells
- lymphocytes
- gamma delta
- methods
- Prior art date
Links
- 210000004475 gamma-delta t lymphocyte Anatomy 0.000 title 1
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 4
- 208000023275 Autoimmune disease Diseases 0.000 abstract 1
- 208000035473 Communicable disease Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 102000054766 genetic haplotypes Human genes 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
Classifications
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- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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- C—CHEMISTRY; METALLURGY
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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- C—CHEMISTRY; METALLURGY
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- C—CHEMISTRY; METALLURGY
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- C07K14/70539—MHC-molecules, e.g. HLA-molecules
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- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
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- C12N2501/23—Interleukins [IL]
- C12N2501/2302—Interleukin-2 (IL-2)
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- C12N2501/23—Interleukins [IL]
- C12N2501/2307—Interleukin-7 (IL-7)
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/515—CD3, T-cell receptor complex
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- C12N2501/599—Cell markers; Cell surface determinants with CD designations not provided for elsewhere
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- C—CHEMISTRY; METALLURGY
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
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- Veterinary Medicine (AREA)
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- General Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Oncology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
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- Mycology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462080500P | 2014-11-17 | 2014-11-17 | |
| PCT/US2015/061189 WO2016081518A2 (en) | 2014-11-17 | 2015-11-17 | Engineered gamma delta t-cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2017006408A true MX2017006408A (es) | 2018-03-23 |
Family
ID=56014675
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2017006408A MX2017006408A (es) | 2014-11-17 | 2015-11-17 | Linfocitos t gamma delta modificados geneticamente. |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US11135245B2 (enExample) |
| EP (2) | EP4545639A3 (enExample) |
| JP (2) | JP7146397B2 (enExample) |
| KR (1) | KR102660362B1 (enExample) |
| CN (2) | CN117143814A (enExample) |
| AU (2) | AU2015350103A1 (enExample) |
| CA (1) | CA2966634C (enExample) |
| DK (1) | DK3220926T3 (enExample) |
| ES (1) | ES3023783T3 (enExample) |
| IL (2) | IL252131B2 (enExample) |
| MX (1) | MX2017006408A (enExample) |
| RU (1) | RU2756247C2 (enExample) |
| WO (1) | WO2016081518A2 (enExample) |
| ZA (1) | ZA201703505B (enExample) |
Families Citing this family (86)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL1814580T3 (pl) | 2004-11-24 | 2017-03-31 | Fred Hutchinson Cancer Research Center | Metody stosowania il-21 do adoptywnej immunoterapii i identyfikacji antygenów guza |
| GB201506423D0 (en) | 2015-04-15 | 2015-05-27 | Tc Biopharm Ltd | Gamma delta T cells and uses thereof |
| JP7146397B2 (ja) | 2014-11-17 | 2022-10-04 | アディセット バイオ, インコーポレイテッド | 改変γδT細胞 |
| SG11201706128PA (en) | 2015-01-27 | 2017-08-30 | Lava Therapeutics B V | Single domain antibodies targeting cd1d |
| GB201507368D0 (en) | 2015-04-30 | 2015-06-17 | Ucl Business Plc | Cell |
| KR102663157B1 (ko) * | 2015-06-09 | 2024-05-13 | 감마델타 테라퓨틱스 엘티디 | Tcr감마 델타 양성 t 세포의 생산 방법 |
| WO2017041106A1 (en) | 2015-09-03 | 2017-03-09 | The Uab Research Foundation | Genetically-engineered drug resistant t cells and methods of using the same |
| CN118421557A (zh) * | 2016-05-12 | 2024-08-02 | 阿迪塞特治疗公司 | 选择性扩增γδT细胞群的方法及其组合物 |
| US10426796B2 (en) * | 2016-06-13 | 2019-10-01 | SMART SURGICAL, Inc. | Compositions for biological systems and methods for preparing and using the same |
| US10456423B2 (en) | 2016-06-13 | 2019-10-29 | SMART SURGICAL, Inc. | Compositions for biological systems and methods for preparing and using the same |
| JP7193862B2 (ja) | 2016-08-03 | 2022-12-21 | ワシントン・ユニバーシティ | キメラ抗原受容体でのt細胞性悪性腫瘍の治療のためのcar-t細胞の遺伝子編集 |
| KR102032354B1 (ko) | 2016-11-11 | 2019-10-16 | 가톨릭대학교 산학협력단 | 신규한 배양보조세포 및 이를 이용한 감마 델타 t 세포의 증식 방법 |
| EP3544996A2 (en) | 2016-11-22 | 2019-10-02 | TCR2 Therapeutics Inc. | Compositions and methods for tcr reprogramming using fusion proteins |
| AU2017382902A1 (en) * | 2016-12-21 | 2019-07-18 | TCR2 Therapeutics Inc. | Engineered T cells for the treatment of cancer |
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