PE20171135A1 - Metodos para seleccionar una linea de celulas t y donador de la misma para terapia celular adoptiva - Google Patents
Metodos para seleccionar una linea de celulas t y donador de la misma para terapia celular adoptivaInfo
- Publication number
- PE20171135A1 PE20171135A1 PE2017000810A PE2017000810A PE20171135A1 PE 20171135 A1 PE20171135 A1 PE 20171135A1 PE 2017000810 A PE2017000810 A PE 2017000810A PE 2017000810 A PE2017000810 A PE 2017000810A PE 20171135 A1 PE20171135 A1 PE 20171135A1
- Authority
- PE
- Peru
- Prior art keywords
- line
- cells
- allogenic
- donor
- selecting
- Prior art date
Links
- 210000001744 T-lymphocyte Anatomy 0.000 title abstract 7
- 238000000034 method Methods 0.000 title abstract 4
- 238000002659 cell therapy Methods 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 abstract 3
- 201000011510 cancer Diseases 0.000 abstract 3
- 230000000694 effects Effects 0.000 abstract 3
- 244000052769 pathogen Species 0.000 abstract 3
- 230000001717 pathogenic effect Effects 0.000 abstract 3
- 108700028369 Alleles Proteins 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
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Abstract
La presente invencion se refiere a un metodo para seleccionar una linea de celulas T alogenicas para administracion terapeutica a un paciente que tiene o se sospecha que tiene un patogeno o cancer. Dicho metodo para seleccionar una linea de celulas T alogenicas comprende seleccionar una linea de celulas T alogenicas al paciente que reconoce al menos un epitopo de un antigeno del patogeno o el cancer usando una representacion que identifica una pluralidad de alelos de HLA y combinaciones de aquellos, y que describe indicaciones de actividades relativas de lineas de celulas T, donde las actividades relativas son medidas relativas de actividad conocida contra el patogeno o contra el cancer presentado por las lineas celulares T. Tambien se refiere a un metodo para seleccionar un donador de quien se deriva una linea de celulas T alogenicas
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201462075856P | 2014-11-05 | 2014-11-05 |
Publications (1)
Publication Number | Publication Date |
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PE20171135A1 true PE20171135A1 (es) | 2017-08-09 |
Family
ID=54754735
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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PE2017000810A PE20171135A1 (es) | 2014-11-05 | 2015-11-04 | Metodos para seleccionar una linea de celulas t y donador de la misma para terapia celular adoptiva |
Country Status (24)
Country | Link |
---|---|
US (2) | US11173205B2 (es) |
EP (1) | EP3215165B1 (es) |
JP (2) | JP7018316B2 (es) |
KR (1) | KR102395528B1 (es) |
CN (2) | CN113768952A (es) |
AR (1) | AR102538A1 (es) |
AU (1) | AU2015343239B2 (es) |
BR (1) | BR112017009475B1 (es) |
CA (1) | CA2966351A1 (es) |
CL (2) | CL2017001110A1 (es) |
CO (1) | CO2017004932A2 (es) |
ES (1) | ES2846747T3 (es) |
FR (1) | FR23C1015I1 (es) |
IL (1) | IL252087B (es) |
MX (1) | MX2017005707A (es) |
MY (1) | MY189857A (es) |
NZ (1) | NZ731321A (es) |
PE (1) | PE20171135A1 (es) |
PH (1) | PH12017500787A1 (es) |
RU (1) | RU2734784C2 (es) |
SG (1) | SG11201703406YA (es) |
TW (1) | TWI673365B (es) |
WO (1) | WO2016073550A1 (es) |
ZA (1) | ZA201703083B (es) |
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GB201121308D0 (en) | 2011-12-12 | 2012-01-25 | Cell Medica Ltd | Process |
US20150010519A1 (en) | 2012-02-09 | 2015-01-08 | Baylor College Of Medicine | Pepmixes to generate multiviral ctls with broad specificity |
CN113768952A (zh) | 2014-11-05 | 2021-12-10 | 纪念斯隆-凯特林癌症中心 | 选择用于过继细胞疗法的t细胞系及其供体的方法 |
NZ736675A (en) * | 2015-05-12 | 2023-03-31 | Memorial Sloan Kettering Cancer Center | Methods of treating epstein-barr virus-associated lymphoproliferative disorders by t cell therapy |
WO2017049291A1 (en) | 2015-09-18 | 2017-03-23 | Baylor College Of Medicine | Immunogenic antigen identification from a pathogen and correlation to clinical efficacy |
KR102592673B1 (ko) | 2016-05-25 | 2023-10-24 | 더 카운실 오브 더 퀸즐랜드 인스티튜트 오브 메디컬 리서치 | 면역요법의 방법 |
WO2018057823A1 (en) | 2016-09-23 | 2018-03-29 | Memorial Sloan Kettering Cancer Center | Generation and use in adoptive immunotherapy of stem cell-like memory t cells |
AU2018218221A1 (en) * | 2017-02-07 | 2019-08-15 | Memorial Sloan Kettering Cancer Center | Use of immune checkpoint modulators in combination with antigen-specific T cells in adoptive immunotherapy |
WO2018217203A1 (en) | 2017-05-25 | 2018-11-29 | Oreilly Richard John | Use of the il-15/il-15ra complex in the generation of antigen-specific t cells for adoptive immunotherapy |
AU2018355145A1 (en) | 2017-10-23 | 2020-04-30 | Atara Biotherapeutics, Inc. | Methods of managing tumor flare in adoptive immunotherapy |
US20200350049A1 (en) * | 2018-01-08 | 2020-11-05 | Atara Biotherapeutics, Inc. | Systems and methods for distributing cell therapies |
EP3765602A1 (en) | 2018-03-14 | 2021-01-20 | Memorial Sloan Kettering Cancer Center | Methods of selecting t cell line for adoptive cellular therapy |
WO2019222762A1 (en) * | 2018-05-18 | 2019-11-21 | Children's National Medical Center | Improved cell therapy compositions for hematopoietic stem cell transplant patients |
CN114502180A (zh) * | 2019-07-29 | 2022-05-13 | 贝勒医学院 | 抗原特异性t细胞库及其制备和治疗使用方法 |
WO2021154882A1 (en) * | 2020-01-27 | 2021-08-05 | H. Lee Moffitt Cancer Center And Research Institute Inc. | Hdac6-inhibited human regulatory t cells |
US11191827B1 (en) * | 2020-12-09 | 2021-12-07 | Tevogen Bio Inc. | COVID-19 peptide specific T-cells and methods of treating and preventing COVID-19 |
WO2023004335A1 (en) * | 2021-07-22 | 2023-01-26 | Board Of Regents, The University Of Texas System | Selection of viral-specific cytotoxic t-cell lines for the management of viral infections |
KR102631682B1 (ko) * | 2021-12-02 | 2024-02-28 | (주)에스엠티바이오 | 면역 세포 공여자의 선별 방법 |
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JP3201610B2 (ja) | 1995-03-17 | 2001-08-27 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 腫瘍を処置する方法 |
KR20000049096A (ko) | 1996-10-11 | 2000-07-25 | 린다 에스. 스티븐슨 | 혼합 림프구와 조합된 종양세포를 사용하는 암 면역요법 |
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AUPO784197A0 (en) | 1997-07-10 | 1997-08-07 | Csl Limited | Treatment of nasopharyngeal carcinoma |
ATE359080T1 (de) | 1997-10-10 | 2007-05-15 | Univ California | Allogene zellkombination enthaltende implantate zur krebsbehandlung |
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AU2011295845B2 (en) | 2010-09-01 | 2016-09-22 | Baylor College Of Medicine | EBV-specific cytotoxic T-lymphocytes for the treatment of locoregional nasopharyngeal carcinoma (NPC) |
CA2812153C (en) | 2010-09-20 | 2020-06-30 | Biontech Ag | Antigen-specific t cell receptors and t cell epitopes |
WO2013006050A1 (en) * | 2011-07-06 | 2013-01-10 | Isa Pharmaceuticals B.V. | Peptides inducing or enhancing an immune response against prostate-specific membrane protein (PSMA) |
CN113768952A (zh) | 2014-11-05 | 2021-12-10 | 纪念斯隆-凯特林癌症中心 | 选择用于过继细胞疗法的t细胞系及其供体的方法 |
EP3765602A1 (en) | 2018-03-14 | 2021-01-20 | Memorial Sloan Kettering Cancer Center | Methods of selecting t cell line for adoptive cellular therapy |
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