MX2016006316A - Inhibidores de mtor para potenciar la respuesta inmunitaria. - Google Patents

Inhibidores de mtor para potenciar la respuesta inmunitaria.

Info

Publication number
MX2016006316A
MX2016006316A MX2016006316A MX2016006316A MX2016006316A MX 2016006316 A MX2016006316 A MX 2016006316A MX 2016006316 A MX2016006316 A MX 2016006316A MX 2016006316 A MX2016006316 A MX 2016006316A MX 2016006316 A MX2016006316 A MX 2016006316A
Authority
MX
Mexico
Prior art keywords
immune response
enhancing
mtor inhibitors
mtor
immune
Prior art date
Application number
MX2016006316A
Other languages
English (en)
Spanish (es)
Inventor
Leon Murphy
Joan Mannick
David Jonathan Glass
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MX2016006316A publication Critical patent/MX2016006316A/es

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    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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    • C—CHEMISTRY; METALLURGY
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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    • G01N33/6854—Immunoglobulins
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    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
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    • C—CHEMISTRY; METALLURGY
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    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
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  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Pulmonology (AREA)
  • Neurology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
MX2016006316A 2013-11-13 2014-11-13 Inhibidores de mtor para potenciar la respuesta inmunitaria. MX2016006316A (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361903636P 2013-11-13 2013-11-13
US201462027121P 2014-07-21 2014-07-21
US201462052629P 2014-09-19 2014-09-19
US201462076142P 2014-11-06 2014-11-06
PCT/US2014/065408 WO2015073644A1 (en) 2013-11-13 2014-11-13 Mtor inhibitors for enhancing the immune response

Publications (1)

Publication Number Publication Date
MX2016006316A true MX2016006316A (es) 2016-07-26

Family

ID=53057999

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016006316A MX2016006316A (es) 2013-11-13 2014-11-13 Inhibidores de mtor para potenciar la respuesta inmunitaria.

Country Status (12)

Country Link
US (4) US20150140036A1 (enExample)
EP (1) EP3068435A1 (enExample)
JP (2) JP2016537345A (enExample)
KR (1) KR20160084438A (enExample)
CN (1) CN105899232A (enExample)
AU (3) AU2014348657A1 (enExample)
BR (1) BR112016010716A8 (enExample)
CA (1) CA2929181A1 (enExample)
EA (1) EA201690987A1 (enExample)
MX (1) MX2016006316A (enExample)
TW (1) TWI679976B (enExample)
WO (1) WO2015073644A1 (enExample)

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JP2015502366A (ja) 2011-12-13 2015-01-22 バック インスティテュート フォー リサーチ オン エイジング 薬物療法を改善するための方法
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CN108348508A (zh) * 2015-09-24 2018-07-31 德雷克塞尔大学 治疗或预防皮肤障碍的新型组合物和方法
WO2017103001A2 (en) * 2015-12-16 2017-06-22 INSERM (Institut National de la Santé et de la Recherche Médicale) Diagnostic markers of immunosenescence and methods for determining the susceptibility to nosocomial infections
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