MX2015012782A - Algoritmo del perfil de expresion genica para calculo de un puntaje de recidiva para un paciente con cancer de riñon. - Google Patents

Algoritmo del perfil de expresion genica para calculo de un puntaje de recidiva para un paciente con cancer de riñon.

Info

Publication number
MX2015012782A
MX2015012782A MX2015012782A MX2015012782A MX2015012782A MX 2015012782 A MX2015012782 A MX 2015012782A MX 2015012782 A MX2015012782 A MX 2015012782A MX 2015012782 A MX2015012782 A MX 2015012782A MX 2015012782 A MX2015012782 A MX 2015012782A
Authority
MX
Mexico
Prior art keywords
kidney cancer
patient
calculating
gene expression
expression profile
Prior art date
Application number
MX2015012782A
Other languages
English (en)
Other versions
MX369911B (es
Inventor
Dejan Knezevic
Steven Shak
George Andrew Watson
Michael R Crager
Tara Maddala
Margarita Lopatin
Audrey Goddard
Christer Svedman
Original Assignee
Genomic Health Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genomic Health Inc filed Critical Genomic Health Inc
Publication of MX2015012782A publication Critical patent/MX2015012782A/es
Publication of MX369911B publication Critical patent/MX369911B/es

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    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C99/00—Subject matter not provided for in other groups of this subclass
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/30—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16Z—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS, NOT OTHERWISE PROVIDED FOR
    • G16Z99/00—Subject matter not provided for in other main groups of this subclass
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medical Informatics (AREA)
  • Pathology (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Theoretical Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Evolutionary Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Data Mining & Analysis (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Databases & Information Systems (AREA)
  • Primary Health Care (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Computing Systems (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

La presente invención proporciona ensayos moleculares basados en algoritmo que implican la medición de los niveles de expresión de genes de una muestra biológica obtenida de un paciente con cáncer de riñón. La presente invención también proporciona métodos de obtención de un puntaje cuantitativo para un paciente con cáncer de riñón en base a la medición de los niveles de expresión de genes de una muestra biológica obtenida de un paciente con cáncer de riñón. Los genes pueden agruparse en subconjuntos de genes funcionales para calcular el puntaje cuantitativo y los subconjuntos de genes pueden ponderarse de acuerdo con su aporte a la recidiva del cáncer.
MX2015012782A 2013-05-30 2014-05-29 Método basado en expresión génica para clasificar pacientes con cãncer de riñón de acuerdo al riesgo de recurrencia. MX369911B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361829100P 2013-05-30 2013-05-30
PCT/US2014/040003 WO2014194078A1 (en) 2013-05-30 2014-05-29 Gene expression profile algorithm for calculating a recurrence score for a patient with kidney cancer

Publications (2)

Publication Number Publication Date
MX2015012782A true MX2015012782A (es) 2016-02-05
MX369911B MX369911B (es) 2019-11-26

Family

ID=51989393

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2015012782A MX369911B (es) 2013-05-30 2014-05-29 Método basado en expresión génica para clasificar pacientes con cãncer de riñón de acuerdo al riesgo de recurrencia.
MX2019013953A MX2019013953A (es) 2013-05-30 2015-09-14 Metodo basado en expresion genica para clasificar pacientes con cancer de riñon de acuerdo al riesgo de recurrencia.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2019013953A MX2019013953A (es) 2013-05-30 2015-09-14 Metodo basado en expresion genica para clasificar pacientes con cancer de riñon de acuerdo al riesgo de recurrencia.

Country Status (12)

Country Link
US (3) US10181008B2 (es)
EP (2) EP3825420A1 (es)
JP (3) JP2016521979A (es)
AU (2) AU2014274135B2 (es)
CA (2) CA2903878C (es)
DK (1) DK3004392T3 (es)
ES (1) ES2829415T3 (es)
HK (1) HK1223132A1 (es)
IL (2) IL240919B (es)
MX (2) MX369911B (es)
SG (2) SG11201506987VA (es)
WO (1) WO2014194078A1 (es)

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EP3978629A1 (en) * 2020-10-01 2022-04-06 Koninklijke Philips N.V. Prediction of an outcome of a bladder or kidney cancer subject
CN113593640B (zh) * 2021-08-03 2023-07-28 哈尔滨市米杰生物科技有限公司 一种鳞癌组织功能状态与细胞组分评估方法及系统
CN117935910B (zh) * 2024-01-26 2024-09-17 华中农业大学 玉米snp位点的筛选方法、装置、电子设备及介质

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Also Published As

Publication number Publication date
NZ752676A (en) 2021-05-28
US20210151122A1 (en) 2021-05-20
JP2020191896A (ja) 2020-12-03
CA3093128C (en) 2023-01-03
EP3004392A1 (en) 2016-04-13
MX2019013953A (es) 2020-01-30
EP3825420A1 (en) 2021-05-26
AU2014274135A1 (en) 2015-09-24
US11551782B2 (en) 2023-01-10
US20190095575A1 (en) 2019-03-28
JP2018161151A (ja) 2018-10-18
US10181008B2 (en) 2019-01-15
EP3004392A4 (en) 2017-01-25
WO2014194078A1 (en) 2014-12-04
US20220044760A9 (en) 2022-02-10
CA3093128A1 (en) 2014-12-04
EP3004392B1 (en) 2020-09-30
IL240919A0 (en) 2015-10-29
NZ711680A (en) 2021-05-28
AU2014274135B2 (en) 2020-04-09
SG11201506987VA (en) 2015-10-29
SG10201709537PA (en) 2017-12-28
CA2903878C (en) 2020-10-27
JP2016521979A (ja) 2016-07-28
IL240919B (en) 2021-06-30
MX369911B (es) 2019-11-26
HK1223132A1 (zh) 2017-07-21
ES2829415T3 (es) 2021-05-31
DK3004392T3 (da) 2020-10-26
AU2020204502B2 (en) 2022-02-17
AU2020204502A1 (en) 2020-07-23
JP7301798B2 (ja) 2023-07-03
CA2903878A1 (en) 2014-12-04
IL283548A (en) 2021-07-29
US20160048632A1 (en) 2016-02-18

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