MX2015008703A - Acido ribonucleico mensajero 124 como biomarcador. - Google Patents

Acido ribonucleico mensajero 124 como biomarcador.

Info

Publication number
MX2015008703A
MX2015008703A MX2015008703A MX2015008703A MX2015008703A MX 2015008703 A MX2015008703 A MX 2015008703A MX 2015008703 A MX2015008703 A MX 2015008703A MX 2015008703 A MX2015008703 A MX 2015008703A MX 2015008703 A MX2015008703 A MX 2015008703A
Authority
MX
Mexico
Prior art keywords
mirna
biomarker
viral infection
mir
efficacy
Prior art date
Application number
MX2015008703A
Other languages
English (en)
Other versions
MX363726B (es
Inventor
Romain Najman
Jamal Tazi
Didier Scherrer
Aude Garcel
Noëlie Campos
Florence Mahuteau-Betzer
Original Assignee
Ct Nat De La Rech Scentifique
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ct Nat De La Rech Scentifique filed Critical Ct Nat De La Rech Scentifique
Publication of MX2015008703A publication Critical patent/MX2015008703A/es
Publication of MX363726B publication Critical patent/MX363726B/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701Specific hybridization probes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/112Disease subtyping, staging or classification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/136Screening for pharmacological compounds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/178Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

Abstract

La presente invención se refiere al uso de al menos un miARN, el al menos un miARN que es el miR-124, como un biomarcador, en particular de una infección viral, o de una eficacia de un tratamiento terapéutico de la infección viral.
MX2015008703A 2013-01-17 2014-01-17 Acido ribonucleico mensajero 124 como biomarcador. MX363726B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP13305053.4A EP2757161A1 (en) 2013-01-17 2013-01-17 miRNA-124 as a biomarker of viral infection
PCT/IB2014/058359 WO2014111892A1 (en) 2013-01-17 2014-01-17 miRNA-124 AS A BIOMARKER

Publications (2)

Publication Number Publication Date
MX2015008703A true MX2015008703A (es) 2016-04-15
MX363726B MX363726B (es) 2019-04-01

Family

ID=47628077

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015008703A MX363726B (es) 2013-01-17 2014-01-17 Acido ribonucleico mensajero 124 como biomarcador.

Country Status (19)

Country Link
US (1) US11441181B2 (es)
EP (2) EP2757161A1 (es)
JP (1) JP6607568B2 (es)
KR (2) KR102412581B1 (es)
CN (1) CN105612261B (es)
AU (2) AU2014206553B2 (es)
BR (1) BR112015016977B1 (es)
CA (1) CA2897563C (es)
DK (1) DK2946022T3 (es)
ES (1) ES2716104T3 (es)
HK (1) HK1218766A1 (es)
HR (1) HRP20190436T1 (es)
MX (1) MX363726B (es)
PL (1) PL2946022T3 (es)
PT (1) PT2946022T (es)
RU (1) RU2687366C2 (es)
TR (1) TR201903401T4 (es)
WO (1) WO2014111892A1 (es)
ZA (1) ZA201504984B (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TR201910781T4 (tr) 2009-06-12 2019-08-21 Abivax Kanser tedavisi için yararlı bileşikler.
US10253020B2 (en) 2009-06-12 2019-04-09 Abivax Compounds for preventing, inhibiting, or treating cancer, AIDS and/or premature aging
EP2757161A1 (en) 2013-01-17 2014-07-23 Splicos miRNA-124 as a biomarker of viral infection
HRP20211839T1 (hr) * 2013-07-05 2022-03-04 Abivax Biciklički spojevi korisni za liječenje bolesti uzrokovanih retrovirusima
EP2974729A1 (en) 2014-07-17 2016-01-20 Abivax Quinoline derivatives for use in the treatment of inflammatory diseases
EP3058940A1 (en) * 2015-02-23 2016-08-24 Abivax Quinoline derivatives for use in the treatment or prevention of viral infection
EP3669874A1 (en) * 2018-12-20 2020-06-24 Abivax Quinoline derivatives for use in the treatment or prevention of cancer
EP3669873A1 (en) 2018-12-20 2020-06-24 Abivax Quinoline derivatives for use ine the traeatment of inflammation diseases
US20220267865A1 (en) * 2019-02-05 2022-08-25 Universidade De Santiago De Compostela In vitro method for the diagnosis of viral infections
EP3881844A1 (en) 2020-03-20 2021-09-22 Abivax Compounds for treating or preventing a coronaviridae infection & methods and uses for assessing the occurrence of a coronaviridae infection
CN115605205A (zh) 2020-03-20 2023-01-13 Abivax公司(Fr) 用于治疗或预防冠状病毒科感染的化合物以及用于评估冠状病毒科感染的发生的方法和用途
EP3884946A1 (en) 2020-03-25 2021-09-29 Abivax Compounds for treating or preventing a coronaviridae infection & methods and uses for assessing the occurrence of a coronaviridae infection
WO2023126951A1 (en) * 2022-01-03 2023-07-06 Yeda Research And Development Co. Ltd. Inhibitors of autophagy-related protein-protein interactions
EP4212156A1 (en) 2022-01-13 2023-07-19 Abivax Combination of 8-chloro-n-(4-(trifluoromethoxy)phenyl)quinolin-2-amine and its derivatives with a s1p receptor modulator
EP4215196A1 (en) 2022-01-24 2023-07-26 Abivax Combination of 8-chloro-n-(4-(trifluoromethoxy)phenyl)quinolin-2-amine and its derivatives with a jak inhibitor

Family Cites Families (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB585362A (en) 1944-08-31 1947-02-05 Francis Henry Swinden Curd New heterocyclic compounds
BE486034A (es) 1947-11-28
DE958647C (de) 1952-12-28 1957-02-21 Hoechst Ag Verfahren zur Herstellung von 7-Amino-2-oxy-4-methyl-chinolinen
FR2387229A1 (fr) 1977-04-13 1978-11-10 Anvar Dipyrido (4,3-b) (3,4-f) indoles, procede d'obtention, application therapeutique et compositions pharmaceutiques les contenant
FR2436786A1 (fr) 1978-09-21 1980-04-18 Anvar Nouveaux derives des pyrido (4,3-b) carbazoles (ellipticines), substitues en position 1 par une chaine polyaminee, leur obtention et leur application a titre de medicaments
US4738710A (en) 1979-11-19 1988-04-19 Ici Australia Limited Herbicidal alkane carboxylic acid derivatives
FR2627493B1 (fr) 1988-02-23 1991-10-31 Sanofi Sa Procede de preparation de derives d'isoquinoleine
FR2645861A1 (fr) 1989-04-17 1990-10-19 Inst Nat Sante Rech Med Utilisation de dipyrido (4,3-b) (3,4-f) indoles pour la preparation de medicaments utiles pour le traitement du sida
US6177401B1 (en) 1992-11-13 2001-01-23 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften Use of organic compounds for the inhibition of Flk-1 mediated vasculogenesis and angiogenesis
US6180632B1 (en) 1997-05-28 2001-01-30 Aventis Pharmaceuticals Products Inc. Quinoline and quinoxaline compounds which inhibit platelet-derived growth factor and/or p56lck tyrosine kinases
DE60008509T2 (de) 1999-04-05 2004-12-16 City Of Hope, Duarte Neue Hemmer von fortgeschrittenen Glykosilierungsendprodukten (AGEs)
UA75055C2 (uk) 1999-11-30 2006-03-15 Пфайзер Продактс Інк. Похідні бензоімідазолу, що використовуються як антипроліферативний засіб, фармацевтична композиція на їх основі
DE10013318A1 (de) 2000-03-17 2001-09-20 Merck Patent Gmbh Formulierung enthaltend Chinoxalinderivate
JP4223287B2 (ja) 2001-01-22 2009-02-12 メモリー・ファーマスーティカルズ・コーポレーション 新規な化合物及び製薬上許容し得るそれらの塩並びにそれらを用いた薬剤組成物
US6498254B1 (en) * 2001-10-29 2002-12-24 Uniroyal Chemical Company, Inc. Antiretroviral compounds and compositions
MXPA04011472A (es) 2002-05-22 2005-02-14 Amgen Inc Derivados de amino-piridina, piridina y piridazina para usarse como ligandos del receptor vaniloide para el tratamiento del dolor.
AU2002950217A0 (en) 2002-07-16 2002-09-12 Prana Biotechnology Limited 8- Hydroxy Quinoline Derivatives
EP1539697A1 (en) 2002-07-19 2005-06-15 Memory Pharmaceutical Corporation Phosphodiesterase 4 inhibitors, including n-substituted aniline and diphenylamine analogs
FR2849474B3 (fr) 2002-12-27 2004-12-03 Olivier Jean Noel Juin Installation de transformation de l'energie cinetique d'un fluide en energie electrique
WO2004078731A1 (fr) 2003-03-06 2004-09-16 'chemical Diversity Research Institute', Ltd. Acides quinoline-carboxyliques et leurs derives et bibliotheque focalisee
EP1601357A4 (en) 2003-03-10 2007-10-03 Schering Corp HETEROCYCLIC KINASE INHIBITORS: METHOD OF USE AND SYNTHESIS
FR2859475A1 (fr) 2003-09-04 2005-03-11 Centre Nat Rech Scient Utilisation de composes derives d'ellipticine et d'aza-ellipticine pour la preparation d'un medicament utile pour le traitement de maladies genetiques resultant de l'alteration des processus d'epissage
FR2859474B1 (fr) 2003-09-04 2006-01-13 Centre Nat Rech Scient Utilisation de composes derives d'indole pour la preparation d'un medicament utile pour le traitement de maladies genetiques resultant de l'alteration des processus d'epissage
JP2007509059A (ja) 2003-10-16 2007-04-12 カイロン コーポレイション 癌の処置のためのRafキナーゼのインヒビターとしての、2,6−二置換キナゾリン、キノキサリン、キノリンおよびイソキノリン
WO2005051301A2 (en) 2003-11-19 2005-06-09 Array Biopharma Inc. Heterocyclic inhibitors of mek and methods of use thereof
WO2005112930A1 (en) 2004-05-21 2005-12-01 Japan Tobacco Inc. Combinations comprising a 4-isoquinolone derivative and anti-hiv agents
CA2585490A1 (en) 2004-11-12 2006-05-18 Galapagos Nv Nitrogen heteroaromatic compounds which bind to the active site of protein kinase enzymes
EP1853265B1 (en) 2005-01-28 2016-01-27 The Government of the United States of America as represented by the Secretary of the Department of Health and Human Services Farnesyltransferase inhibitors for use in the treatment of laminopathies, cellular aging and atherosclerosis
AU2006227833A1 (en) 2005-03-18 2006-09-28 The Regents Of The University Of California Compounds having activity in correcting mutant-CFTR processing and uses thereof
US20090088513A1 (en) 2005-06-29 2009-04-02 Adeka Corporation Resin additive composition and resin composition
WO2007042899A2 (en) * 2005-10-10 2007-04-19 Council Of Scientific And Industrial Research Human microrna targets in hiv genome and a method of identification thereof
RU2350650C2 (ru) * 2006-04-17 2009-03-27 Общество с ограниченной ответственностью "Биосинтез" (ООО "Биосинтез") РЕКОМБИНАНТНАЯ ПЛАЗМИДНАЯ ДНК pVar15-HIV-LTR, НЕСУЩАЯ КЛОНИРОВАННЫЙ ФРАГМЕНТ ГЕНОМА ВИЧ-1 ТИПА ИЗ КОНСЕРВАТИВНОГО УЧАСТКА 5'-LTR ПОСЛЕДОВАТЕЛЬНОСТИ, РЕКОМБИНАНТНАЯ ПЛАЗМИДНАЯ ДНК pBluKSM-HIV-LTR mod, НЕСУЩАЯ КЛОНИРОВАННЫЙ МОДИФИЦИРОВАННЫЙ ФРАГМЕНТ ЭТОГО ЖЕ УЧАСТКА ГЕНОМА ВИЧ-1 ТИПА, ТЕСТ-НАБОР ДЛЯ КОЛИЧЕСТВЕННОЙ ЭКСПРЕСС-ИДЕНТИФИКАЦИИ ГЕНОМА ВИЧ-1 ЛЮБОГО ТИПА В ПРОБЕ И СПОСОБ С ЕГО ИСПОЛЬЗОВАНИЕМ
DK2044026T3 (da) 2006-06-22 2014-06-30 Prana Biotechnology Ltd Fremgangsmde til behandling af cerebral glioma tumor
FR2903312B1 (fr) 2006-07-05 2008-09-26 Univ Aix Marseille Ii Utilisation d'inhibiteurs d'hmg-coa reductase et de farnesyl-pyrophosphate synthase dans la preparation d'un medicament
WO2008008234A1 (en) 2006-07-07 2008-01-17 Targegen, Inc. 2-amino-5-substituted pyrimidine inhibitors
JP5491199B2 (ja) 2007-01-19 2014-05-14 アルデア バイオサイエンシズ,インコーポレイティド Mekのインヒビター
FR2912745A1 (fr) 2007-02-19 2008-08-22 Centre Nat Rech Scient Nouveaux composes derives d'indole et compositions pharmaceutiques les contenant
CA2681481A1 (en) 2007-03-16 2008-09-25 Mount Sinai School Of Medicine Induction and/or maintenance of tumor dormancy by disruption of urokinase plasminogen activator receptor-integrin interaction
TWI371445B (en) 2007-05-17 2012-09-01 Lg Chemical Ltd New anthracene derivatives and organic electronic device using the same
WO2008153692A2 (en) * 2007-05-22 2008-12-18 The Brigham And Women's Hospital, Inc. Microrna expression profiling of cerebrospinal fluid
UY31272A1 (es) 2007-08-10 2009-01-30 Almirall Lab Nuevos derivados de ácido azabifenilaminobenzoico
MX2010001576A (es) 2007-08-15 2010-09-14 Memory Pharm Corp Compuestos 3´sustituidos que tienen afinidad con el receptor 5-hidroxitriptamina 6 (5-ht6).
WO2009029617A1 (en) 2007-08-27 2009-03-05 Kalypsys, Inc. Diarylamine-substituted quinolones useful as inducible nitric oxide synthase inhibitors
CA2710196A1 (en) * 2007-12-20 2009-07-09 Celgene Corporation Use of micro-rna as a biomarker of immunomodulatory drug activity
KR100974562B1 (ko) 2007-12-31 2010-08-06 다우어드밴스드디스플레이머티리얼 유한회사 신규한 유기 발광 화합물 및 이를 발광재료로서 채용하고있는 유기 발광 소자
FR2926297B1 (fr) 2008-01-10 2013-03-08 Centre Nat Rech Scient Molecules chimiques inhibitrices du mecanisme d'epissage pour traiter des maladies resultant d'anomalies d'epissage.
JP2009174368A (ja) 2008-01-23 2009-08-06 Toyota Motor Corp 内燃機関の排気浄化装置
EP2271931A4 (en) * 2008-04-25 2011-10-12 Merck Sharp & Dohme MICRO-RNA BIOMARKERS FOR TISSUE INJURIES
US20160041153A1 (en) * 2008-11-12 2016-02-11 Kirk Brown Biomarker compositions and markers
JP2012520891A (ja) * 2009-03-19 2012-09-10 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング スルホニルキノリンの製造方法
JP5647673B2 (ja) * 2009-05-05 2015-01-07 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ブロモ置換キノリンの調製方法
EP2266972A1 (en) 2009-06-12 2010-12-29 Splicos New chemical molecules that inhibit the splicing mechanism for treating diseases resulting from splicing anomalies
US10253020B2 (en) 2009-06-12 2019-04-09 Abivax Compounds for preventing, inhibiting, or treating cancer, AIDS and/or premature aging
MX2019008390A (es) 2009-06-12 2019-09-09 Abivax Compuestos utiles para tratar cancer.
TR201910781T4 (tr) 2009-06-12 2019-08-21 Abivax Kanser tedavisi için yararlı bileşikler.
WO2010151755A2 (en) 2009-06-25 2010-12-29 The Brigham And Women's Hospital, Inc. TREATMENT OF INFLAMMATORY DISEASES USING miR-124
CA2780222C (en) * 2009-11-04 2021-11-16 Diamir, Llc Methods of using small rna from bodily fluids for diagnosis and monitoring of neurodegenerative diseases
EP2465502A1 (en) 2010-12-15 2012-06-20 Société Splicos Compounds useful for treating AIDS
WO2012118988A1 (en) * 2011-03-01 2012-09-07 The Scripps Research Institute Direct reprogramming of human fibroblasts to functional neurons under defined conditions
CA2848654C (en) * 2011-09-15 2021-07-20 Self-Screen B.V. Methylation analysis on self-samples as triage tool for hpv-positive women
WO2014055944A1 (en) 2012-10-04 2014-04-10 Oyagen, Inc. Small molecules as anti-hiv agents that disrupt vif self-association and methods of use thereof
EP2757161A1 (en) 2013-01-17 2014-07-23 Splicos miRNA-124 as a biomarker of viral infection
EP2975034A1 (en) 2014-07-17 2016-01-20 Abivax A quinoline derivative for the treatment of inflammatory diseases and AIDS
EP2974729A1 (en) 2014-07-17 2016-01-20 Abivax Quinoline derivatives for use in the treatment of inflammatory diseases
EP3059236A1 (en) 2015-02-23 2016-08-24 Abivax A new quinoline derivative for use in the treatment and prevention of viral infections
DK3429998T3 (da) 2016-03-18 2021-11-22 Prosynergia S A R L Fremgangsmåde til fremstilling af quinolin-2-yl-phenylaminderivater og disses salte

Also Published As

Publication number Publication date
US11441181B2 (en) 2022-09-13
MX363726B (es) 2019-04-01
RU2687366C2 (ru) 2019-05-13
ZA201504984B (en) 2016-09-28
CA2897563C (en) 2021-08-31
TR201903401T4 (tr) 2019-04-22
HRP20190436T1 (hr) 2019-06-14
BR112015016977B1 (pt) 2022-11-08
KR102575595B1 (ko) 2023-09-06
CN105612261B (zh) 2019-06-18
AU2014206553A1 (en) 2015-07-23
KR20150109407A (ko) 2015-10-01
US20150361491A1 (en) 2015-12-17
WO2014111892A1 (en) 2014-07-24
KR102412581B1 (ko) 2022-06-23
PT2946022T (pt) 2019-03-21
CA2897563A1 (en) 2014-07-24
JP6607568B2 (ja) 2019-11-20
DK2946022T3 (en) 2019-04-08
CN105612261A (zh) 2016-05-25
HK1218766A1 (zh) 2017-03-10
JP2016505268A (ja) 2016-02-25
AU2019283919A1 (en) 2020-01-16
RU2015133373A (ru) 2017-02-21
ES2716104T3 (es) 2019-06-10
BR112015016977A2 (es) 2017-08-15
KR20220038551A (ko) 2022-03-28
EP2946022A1 (en) 2015-11-25
PL2946022T3 (pl) 2019-06-28
AU2014206553B2 (en) 2020-01-16
EP2946022B1 (en) 2019-01-09
EP2757161A1 (en) 2014-07-23

Similar Documents

Publication Publication Date Title
MX363726B (es) Acido ribonucleico mensajero 124 como biomarcador.
EP3332007A4 (en) RNA INTERFERENCE THERAPY FOR HEPATITIS B VIRUS INFECTION
IL240488A0 (en) Vaccine preparation for mers corona virus infection
IL240765A0 (en) Macrocyclic daza-furanones for the treatment of viral infections
SI3160476T1 (sl) Substituirani nukleozidi, nukleotidi in njihovi analogi, za uporabo v zdravljenju virusne okužbe
ZA201701643B (en) Pyrrolopyrimidines for use in influenza virus infection
EP2953624A4 (en) METHOD FOR THE TREATMENT OF MICROBIAL INFECTIONS, INCLUDING MASTITIS
EP3116484A4 (en) Treating diseases using nitric oxide releasing solutions
IL242770B (en) A therapeutic combination that includes oxazolidinone-quinolones for use in the treatment of bacterial infections
EP2994140A4 (en) Methods for treating hcv infection
BR112014030159A2 (pt) agente para tratamento de floculação.
WO2014113492A3 (en) Anti-viral compounds
IN2013MU03216A (es)
EP2969006A4 (en) COMPOSITIONS AND METHODS FOR TREATING INFECTION WITH IMMUNODEFICIENCY VIRUSES
GB201402909D0 (en) Treating infection
EA201691036A1 (ru) Новое соединение для лечения тяжелой гипогликемии
EA201690914A1 (ru) Новое соединение для лечения тяжелой гипогликемии
IL253878A0 (en) An effective substance for the treatment of respiratory inflammation
EP3352764A4 (en) COMBINATION THERAPY FOR EV71 INFECTION
EP3000478A4 (en) Therapeutic or prophylactic agent for immunodeficiency virus infection
FR3017550B1 (fr) Machine de traitement de dechets infectieux, notamment medicaux
EP3235479A4 (en) Absorbent, disposable, re-fastenable undergarment
SG10201903630UA (en) Iminosugars useful for the treatment of viral diseases
EP3088523A4 (en) Sirna targeting prk2, which is hepatitis c virus therapeutic agent
EA201690709A1 (ru) Применение одипарцила в лечении мукополисахаридоза

Legal Events

Date Code Title Description
FG Grant or registration