MX2011011025A - Preparacion de c-piracin-metilaminas. - Google Patents
Preparacion de c-piracin-metilaminas.Info
- Publication number
- MX2011011025A MX2011011025A MX2011011025A MX2011011025A MX2011011025A MX 2011011025 A MX2011011025 A MX 2011011025A MX 2011011025 A MX2011011025 A MX 2011011025A MX 2011011025 A MX2011011025 A MX 2011011025A MX 2011011025 A MX2011011025 A MX 2011011025A
- Authority
- MX
- Mexico
- Prior art keywords
- methylamines
- pyrazine
- preparation
- dichloropyrazine
- heteroaryl
- Prior art date
Links
- MLCNOCRGSBCAGH-UHFFFAOYSA-N 2,3-dichloropyrazine Chemical compound ClC1=NC=CN=C1Cl MLCNOCRGSBCAGH-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- -1 diaryl imine Chemical class 0.000 abstract 1
- 125000001072 heteroaryl group Chemical group 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000003107 substituted aryl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/20—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/16—Halogen atoms; Nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17091109P | 2009-04-20 | 2009-04-20 | |
| PCT/US2010/031547 WO2010123792A1 (en) | 2009-04-20 | 2010-04-19 | Preparation of c-pyrazine-methylamines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2011011025A true MX2011011025A (es) | 2011-11-02 |
Family
ID=42269933
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2011011025A MX2011011025A (es) | 2009-04-20 | 2010-04-19 | Preparacion de c-piracin-metilaminas. |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US8513415B2 (enExample) |
| EP (1) | EP2421837A1 (enExample) |
| JP (1) | JP2012524119A (enExample) |
| KR (1) | KR20120020099A (enExample) |
| CN (1) | CN102405214A (enExample) |
| BR (1) | BRPI1016245A2 (enExample) |
| CA (1) | CA2752826A1 (enExample) |
| MX (1) | MX2011011025A (enExample) |
| WO (1) | WO2010123792A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2168968B1 (en) | 2004-04-02 | 2017-08-23 | OSI Pharmaceuticals, LLC | 6,6-bicyclic ring substituted heterobicyclic protein kinase inhibitors |
| US8778964B2 (en) | 2012-11-05 | 2014-07-15 | Bayer Pharma Aktiengesellschaft | Hydroxy-substituted imidazo[1,2-a]-pyridinecarboxamides and their use |
| CN103214424B (zh) * | 2013-04-25 | 2015-05-13 | 兰州康寓信生物科技有限公司 | 吡嗪甲胺衍生物的合成方法 |
| CN105992765A (zh) | 2013-08-08 | 2016-10-05 | 拜耳制药股份公司 | 取代的吡唑并[1,5-a]吡啶-3-甲酰胺及其用途 |
| CN107257796A (zh) | 2014-12-02 | 2017-10-17 | 拜耳医药股份有限公司 | 取代的吡唑并[1,5‑a]吡啶和咪唑并[1,2‑a]吡嗪及其用途 |
| US10214526B2 (en) | 2015-02-05 | 2019-02-26 | Bayer Pharma Aktiengesellschaft | Substituted pyrazolo[1,5-a]-pyridine-3-carboxamides and use thereof |
| CN109553570A (zh) * | 2017-09-27 | 2019-04-02 | 胜兴化工(上海)有限公司 | 3-氯-5-三氟甲基-2-吡啶甲胺盐的制备方法 |
| CN109182286B (zh) * | 2018-09-21 | 2021-07-30 | 泰州学院 | 一种改进的氰基还原酶及其在合成3-氯吡嗪-2甲胺中的应用 |
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| WO2012129145A1 (en) | 2011-03-18 | 2012-09-27 | OSI Pharmaceuticals, LLC | Nscle combination therapy |
-
2010
- 2010-04-19 US US13/265,363 patent/US8513415B2/en not_active Expired - Fee Related
- 2010-04-19 EP EP10714546A patent/EP2421837A1/en not_active Withdrawn
- 2010-04-19 MX MX2011011025A patent/MX2011011025A/es not_active Application Discontinuation
- 2010-04-19 KR KR1020117020844A patent/KR20120020099A/ko not_active Withdrawn
- 2010-04-19 WO PCT/US2010/031547 patent/WO2010123792A1/en not_active Ceased
- 2010-04-19 JP JP2012507282A patent/JP2012524119A/ja active Pending
- 2010-04-19 BR BRPI1016245-3A patent/BRPI1016245A2/pt not_active IP Right Cessation
- 2010-04-19 CA CA2752826A patent/CA2752826A1/en not_active Abandoned
- 2010-04-19 CN CN2010800174272A patent/CN102405214A/zh active Pending
-
2013
- 2013-05-23 US US13/901,054 patent/US20130261306A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| KR20120020099A (ko) | 2012-03-07 |
| WO2010123792A1 (en) | 2010-10-28 |
| EP2421837A1 (en) | 2012-02-29 |
| US20120041202A1 (en) | 2012-02-16 |
| US20130261306A1 (en) | 2013-10-03 |
| US8513415B2 (en) | 2013-08-20 |
| CN102405214A (zh) | 2012-04-04 |
| JP2012524119A (ja) | 2012-10-11 |
| CA2752826A1 (en) | 2010-10-28 |
| BRPI1016245A2 (pt) | 2015-09-01 |
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