MX352607B - Proceso para la preparacion de benzoxaboroles. - Google Patents

Proceso para la preparacion de benzoxaboroles.

Info

Publication number
MX352607B
MX352607B MX2012011632A MX2012011632A MX352607B MX 352607 B MX352607 B MX 352607B MX 2012011632 A MX2012011632 A MX 2012011632A MX 2012011632 A MX2012011632 A MX 2012011632A MX 352607 B MX352607 B MX 352607B
Authority
MX
Mexico
Prior art keywords
benzoxaboroles
preparing
compound
formula
pharmaceutically acceptable
Prior art date
Application number
MX2012011632A
Other languages
English (en)
Other versions
MX2012011632A (es
Inventor
J Conde Jose
John Kowalski Anthony
Allen Zajac Matthew
Original Assignee
Glaxosmithkline Llc Star
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Llc Star filed Critical Glaxosmithkline Llc Star
Publication of MX2012011632A publication Critical patent/MX2012011632A/es
Publication of MX352607B publication Critical patent/MX352607B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B31/00—Reduction in general
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/025—Boronic and borinic acid compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/04—Esters of boric acids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invención es un proceso que comprende poner en contacto un compuesto de la fórmula A: (Ver Formula) o una sal farmacéuticamente aceptable del mismo; con un reactivo de desprotección, para formar un compuesto de la fórmula A: (Ver formula).
MX2012011632A 2010-04-07 2011-04-06 Proceso para la preparacion de benzoxaboroles. MX352607B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32164210P 2010-04-07 2010-04-07
PCT/US2011/031384 WO2011127143A1 (en) 2010-04-07 2011-04-06 Process for preparing benzoxaboroles

Publications (2)

Publication Number Publication Date
MX2012011632A MX2012011632A (es) 2013-02-27
MX352607B true MX352607B (es) 2017-11-30

Family

ID=44763260

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2012011632A MX352607B (es) 2010-04-07 2011-04-06 Proceso para la preparacion de benzoxaboroles.

Country Status (17)

Country Link
US (2) US9243003B2 (es)
EP (1) EP2555625B1 (es)
JP (1) JP5603998B2 (es)
KR (1) KR101508562B1 (es)
CN (1) CN102821609B (es)
AR (1) AR080834A1 (es)
AU (1) AU2011237681B2 (es)
BR (1) BR112012024682B1 (es)
CA (1) CA2794684C (es)
EA (1) EA021532B1 (es)
ES (1) ES2710105T3 (es)
IL (1) IL222103A (es)
MX (1) MX352607B (es)
SG (1) SG184268A1 (es)
TW (1) TWI503324B (es)
WO (1) WO2011127143A1 (es)
ZA (1) ZA201207386B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7767657B2 (en) 2005-02-16 2010-08-03 Anacor Pharmaceuticals, Inc. Boron-containing small molecules
US9440994B2 (en) 2009-08-14 2016-09-13 Anacor Pharmaceuticals, Inc. Boron containing small molecules as antiprotozoal agents
WO2011094450A1 (en) 2010-01-27 2011-08-04 Anacor Pharmaceuticals, Inc Boron-containing small molecules
US8530452B2 (en) 2011-12-22 2013-09-10 Micurx Pharmaceuticals, Inc. Tricyclic boron compounds for antimicrobial therapy
AP2015008638A0 (en) 2013-02-01 2015-08-31 Anacor Pharmaceuticals Inc Boron-containing small molecules as antiprotozoal agents
CN105143281B (zh) * 2013-03-15 2018-06-01 尤尼威蒂恩技术有限责任公司 用于烯烃聚合催化剂的三齿氮类配体
KR101636431B1 (ko) * 2013-07-30 2016-07-05 동아에스티 주식회사 트리사이클릭 벤즈옥사보롤 화합물, 이의 제조방법 및 용도
EP4029870A1 (en) 2013-08-09 2022-07-20 GlaxoSmithKline Intellectual Property (No.2) Limited Tricyclic benzoxaborole compounds and uses thereof
EA038093B1 (ru) * 2013-12-20 2021-07-05 Глаксосмитклайн Интеллекчуал Проперти (№2) Лимитед Способ лечения заболевания, вызванного инфекцией комплекса mycobacterium tuberculosis, с использованием (s)-(3-хлор-7,8-дигидро-2h-1,6,9-триокса-9a-борабензо[cd]азулен-2-ил)метанамина или его фармацевтически приемлемой соли
MA41494B1 (fr) 2015-02-12 2020-10-28 Glaxosmithkline Ip No 2 Ltd Composés benzoxaborole substitués en position 4 et utilisations associées

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0947498B1 (en) * 1996-12-02 2004-09-15 Chisso Corporation Optically active nitro alcohol derivatives, optically active amino alcohol derivatives, and process for preparing the same
EP1567464B1 (en) * 2002-12-02 2007-04-18 Solvias AG Catalytic hydrogeneration of carbon-heteroatom double bonds
WO2006096131A1 (en) * 2005-03-08 2006-09-14 Agency For Science, Technology And Research Chiral bisoxazoline catalysts
KR100848491B1 (ko) * 2007-01-16 2008-07-28 영진약품공업주식회사 베타아미노기를 갖는 2-싸이아졸리딘 유도체, 이의약학적으로 허용 가능한 염 및 이의 제조 방법
JO3396B1 (ar) * 2007-06-20 2019-10-20 Anacor Pharmaceuticals Inc جزيئات صغيرة تحتوي على البورون

Also Published As

Publication number Publication date
JP2013523826A (ja) 2013-06-17
US9243003B2 (en) 2016-01-26
US20160168168A1 (en) 2016-06-16
ES2710105T3 (es) 2019-04-23
ZA201207386B (en) 2014-03-26
AU2011237681A1 (en) 2012-11-29
CA2794684A1 (en) 2011-10-13
AU2011237681B2 (en) 2015-01-22
SG184268A1 (en) 2012-10-30
KR101508562B1 (ko) 2015-04-07
EP2555625A4 (en) 2014-10-15
WO2011127143A1 (en) 2011-10-13
KR20130006506A (ko) 2013-01-16
TWI503324B (zh) 2015-10-11
TW201202257A (en) 2012-01-16
CA2794684C (en) 2018-04-24
EP2555625B1 (en) 2018-11-14
AR080834A1 (es) 2012-05-09
EA201290872A1 (ru) 2013-04-30
BR112012024682A2 (pt) 2020-07-28
IL222103A (en) 2016-12-29
BR112012024682B1 (pt) 2021-06-08
MX2012011632A (es) 2013-02-27
CN102821609B (zh) 2015-03-25
EA021532B1 (ru) 2015-07-30
EP2555625A1 (en) 2013-02-13
US20130035501A1 (en) 2013-02-07
CN102821609A (zh) 2012-12-12
JP5603998B2 (ja) 2014-10-08

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