MX2010004547A - Pegilacion por la tecnica de acoplamiento y bloqueo (dnl). - Google Patents

Pegilacion por la tecnica de acoplamiento y bloqueo (dnl).

Info

Publication number
MX2010004547A
MX2010004547A MX2010004547A MX2010004547A MX2010004547A MX 2010004547 A MX2010004547 A MX 2010004547A MX 2010004547 A MX2010004547 A MX 2010004547A MX 2010004547 A MX2010004547 A MX 2010004547A MX 2010004547 A MX2010004547 A MX 2010004547A
Authority
MX
Mexico
Prior art keywords
sequence
peg
moiety
pegylated
effector
Prior art date
Application number
MX2010004547A
Other languages
English (en)
Spanish (es)
Inventor
William Mcbride
Chien-Hsing Chang
Edmund Rossi
David Goldenberg
Original Assignee
Ibc Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ibc Pharmaceuticals Inc filed Critical Ibc Pharmaceuticals Inc
Publication of MX2010004547A publication Critical patent/MX2010004547A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
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    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1816—Erythropoietin [EPO]
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    • A61K51/1045—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants
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    • B—PERFORMING OPERATIONS; TRANSPORTING
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MX2010004547A 2007-10-26 2008-10-24 Pegilacion por la tecnica de acoplamiento y bloqueo (dnl). MX2010004547A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/925,408 US7666400B2 (en) 2005-04-06 2007-10-26 PEGylation by the dock and lock (DNL) technique
PCT/US2008/081085 WO2009055653A1 (en) 2007-10-26 2008-10-24 Pegylation by the dock and lock (dnl) technique

Publications (1)

Publication Number Publication Date
MX2010004547A true MX2010004547A (es) 2010-07-05

Family

ID=40580038

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010004547A MX2010004547A (es) 2007-10-26 2008-10-24 Pegilacion por la tecnica de acoplamiento y bloqueo (dnl).

Country Status (10)

Country Link
US (5) US7666400B2 (enExample)
EP (1) EP2197468B1 (enExample)
JP (2) JP5577558B2 (enExample)
KR (1) KR101583388B1 (enExample)
CN (1) CN101951939B (enExample)
AU (1) AU2008316741B9 (enExample)
CA (1) CA2696160C (enExample)
IL (1) IL204066A (enExample)
MX (1) MX2010004547A (enExample)
WO (1) WO2009055653A1 (enExample)

Families Citing this family (117)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7666400B2 (en) * 2005-04-06 2010-02-23 Ibc Pharmaceuticals, Inc. PEGylation by the dock and lock (DNL) technique
US7534866B2 (en) * 2005-10-19 2009-05-19 Ibc Pharmaceuticals, Inc. Methods and compositions for generating bioactive assemblies of increased complexity and uses
US7550143B2 (en) * 2005-04-06 2009-06-23 Ibc Pharmaceuticals, Inc. Methods for generating stably linked complexes composed of homodimers, homotetramers or dimers of dimers and uses
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US7666400B2 (en) 2010-02-23
HK1148471A1 (en) 2011-09-09
KR20100085932A (ko) 2010-07-29
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US20090060862A1 (en) 2009-03-05
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US8277817B2 (en) 2012-10-02
JP2011500842A (ja) 2011-01-06
JP5779789B2 (ja) 2015-09-16
CN101951939A (zh) 2011-01-19
CN101951939B (zh) 2013-11-20
WO2009055653A1 (en) 2009-04-30
US9872920B2 (en) 2018-01-23
US7981398B2 (en) 2011-07-19
EP2197468A1 (en) 2010-06-23
EP2197468A4 (en) 2012-04-25
AU2008316741B2 (en) 2013-12-19
IL204066A (en) 2015-06-30
CA2696160C (en) 2017-12-19
US20130177532A1 (en) 2013-07-11
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CA2696160A1 (en) 2009-04-30

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