JP5577558B2 - ドック・ロック(dnl)技術によるpeg化 - Google Patents
ドック・ロック(dnl)技術によるpeg化 Download PDFInfo
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- JP5577558B2 JP5577558B2 JP2010531272A JP2010531272A JP5577558B2 JP 5577558 B2 JP5577558 B2 JP 5577558B2 JP 2010531272 A JP2010531272 A JP 2010531272A JP 2010531272 A JP2010531272 A JP 2010531272A JP 5577558 B2 JP5577558 B2 JP 5577558B2
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- Prior art keywords
- moiety
- ddd
- pegylated
- therapeutic agent
- complex
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- Public Health (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
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- Gastroenterology & Hepatology (AREA)
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- Diabetes (AREA)
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- Orthopedic Medicine & Surgery (AREA)
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- Theoretical Computer Science (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/925,408 | 2007-10-26 | ||
| US11/925,408 US7666400B2 (en) | 2005-04-06 | 2007-10-26 | PEGylation by the dock and lock (DNL) technique |
| PCT/US2008/081085 WO2009055653A1 (en) | 2007-10-26 | 2008-10-24 | Pegylation by the dock and lock (dnl) technique |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014040570A Division JP5779789B2 (ja) | 2007-10-26 | 2014-03-03 | ドック・ロック(dnl)技術によるpeg化 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011500842A JP2011500842A (ja) | 2011-01-06 |
| JP2011500842A5 JP2011500842A5 (enExample) | 2011-12-08 |
| JP5577558B2 true JP5577558B2 (ja) | 2014-08-27 |
Family
ID=40580038
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010531272A Active JP5577558B2 (ja) | 2007-10-26 | 2008-10-24 | ドック・ロック(dnl)技術によるpeg化 |
| JP2014040570A Active JP5779789B2 (ja) | 2007-10-26 | 2014-03-03 | ドック・ロック(dnl)技術によるpeg化 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014040570A Active JP5779789B2 (ja) | 2007-10-26 | 2014-03-03 | ドック・ロック(dnl)技術によるpeg化 |
Country Status (10)
| Country | Link |
|---|---|
| US (5) | US7666400B2 (enExample) |
| EP (1) | EP2197468B1 (enExample) |
| JP (2) | JP5577558B2 (enExample) |
| KR (1) | KR101583388B1 (enExample) |
| CN (1) | CN101951939B (enExample) |
| AU (1) | AU2008316741B9 (enExample) |
| CA (1) | CA2696160C (enExample) |
| IL (1) | IL204066A (enExample) |
| MX (1) | MX2010004547A (enExample) |
| WO (1) | WO2009055653A1 (enExample) |
Families Citing this family (117)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7666400B2 (en) | 2005-04-06 | 2010-02-23 | Ibc Pharmaceuticals, Inc. | PEGylation by the dock and lock (DNL) technique |
| US7550143B2 (en) | 2005-04-06 | 2009-06-23 | Ibc Pharmaceuticals, Inc. | Methods for generating stably linked complexes composed of homodimers, homotetramers or dimers of dimers and uses |
| US7534866B2 (en) * | 2005-10-19 | 2009-05-19 | Ibc Pharmaceuticals, Inc. | Methods and compositions for generating bioactive assemblies of increased complexity and uses |
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| US20130177532A1 (en) | 2013-07-11 |
| CA2696160A1 (en) | 2009-04-30 |
| AU2008316741B2 (en) | 2013-12-19 |
| CA2696160C (en) | 2017-12-19 |
| IL204066A (en) | 2015-06-30 |
| KR101583388B1 (ko) | 2016-01-07 |
| CN101951939A (zh) | 2011-01-19 |
| MX2010004547A (es) | 2010-07-05 |
| JP2011500842A (ja) | 2011-01-06 |
| WO2009055653A1 (en) | 2009-04-30 |
| US9457100B2 (en) | 2016-10-04 |
| KR20100085932A (ko) | 2010-07-29 |
| US20090060862A1 (en) | 2009-03-05 |
| US20160361435A1 (en) | 2016-12-15 |
| AU2008316741B9 (en) | 2014-02-06 |
| US20100261885A1 (en) | 2010-10-14 |
| US9872920B2 (en) | 2018-01-23 |
| JP2014129395A (ja) | 2014-07-10 |
| CN101951939B (zh) | 2013-11-20 |
| US20110236352A1 (en) | 2011-09-29 |
| US8277817B2 (en) | 2012-10-02 |
| EP2197468A1 (en) | 2010-06-23 |
| AU2008316741A1 (en) | 2009-04-30 |
| EP2197468B1 (en) | 2015-07-29 |
| EP2197468A4 (en) | 2012-04-25 |
| US7666400B2 (en) | 2010-02-23 |
| JP5779789B2 (ja) | 2015-09-16 |
| US7981398B2 (en) | 2011-07-19 |
| HK1148471A1 (en) | 2011-09-09 |
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