MX2010002556A - Metodos y sistemas para determinar la variacion del numero de copia. - Google Patents

Metodos y sistemas para determinar la variacion del numero de copia.

Info

Publication number
MX2010002556A
MX2010002556A MX2010002556A MX2010002556A MX2010002556A MX 2010002556 A MX2010002556 A MX 2010002556A MX 2010002556 A MX2010002556 A MX 2010002556A MX 2010002556 A MX2010002556 A MX 2010002556A MX 2010002556 A MX2010002556 A MX 2010002556A
Authority
MX
Mexico
Prior art keywords
copy number
methods
systems
number variation
variation determination
Prior art date
Application number
MX2010002556A
Other languages
English (en)
Inventor
Ramesh Ramakrishnan
Original Assignee
Fluidigm Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fluidigm Corp filed Critical Fluidigm Corp
Publication of MX2010002556A publication Critical patent/MX2010002556A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6851—Quantitative amplification
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells

Abstract

La presente invención es concerniente con métodos y sistemas para determinar la variación del número de copia de un polinucleótido objetivo en un genoma de un sujeto, que incluye técnicas a base de amplificación. Los métodos pueden incluir preamplificación de la muestra seguida por distribución de muestra y una pluralidad de volúmenes de reacción, detección cuantitativa de un polinucleótido objetivo y un polinucleótido de referencia y análisis para determinar el número de copia relativo de la secuencia de polinucleotido objetivo en el genoma del sujeto.
MX2010002556A 2007-09-07 2008-09-08 Metodos y sistemas para determinar la variacion del numero de copia. MX2010002556A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US96789707P 2007-09-07 2007-09-07
PCT/US2008/075636 WO2009033178A1 (en) 2007-09-07 2008-09-08 Copy number variation determination, methods and systems

Publications (1)

Publication Number Publication Date
MX2010002556A true MX2010002556A (es) 2010-08-02

Family

ID=40429425

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010002556A MX2010002556A (es) 2007-09-07 2008-09-08 Metodos y sistemas para determinar la variacion del numero de copia.

Country Status (14)

Country Link
US (3) US8148078B2 (es)
EP (1) EP2198293B1 (es)
JP (1) JP5707132B2 (es)
KR (1) KR101518085B1 (es)
CN (1) CN101821619B (es)
AT (1) ATE541946T1 (es)
AU (1) AU2008295992B2 (es)
BR (1) BRPI0816393A2 (es)
CA (1) CA2698545C (es)
EA (1) EA018555B1 (es)
ES (1) ES2380844T3 (es)
IL (1) IL204288A (es)
MX (1) MX2010002556A (es)
WO (1) WO2009033178A1 (es)

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