MX2007014053A - N-arilpirrolidinas substituidas como moduladores selectivos de receptor de androgeno. - Google Patents
N-arilpirrolidinas substituidas como moduladores selectivos de receptor de androgeno.Info
- Publication number
- MX2007014053A MX2007014053A MX2007014053A MX2007014053A MX2007014053A MX 2007014053 A MX2007014053 A MX 2007014053A MX 2007014053 A MX2007014053 A MX 2007014053A MX 2007014053 A MX2007014053 A MX 2007014053A MX 2007014053 A MX2007014053 A MX 2007014053A
- Authority
- MX
- Mexico
- Prior art keywords
- methyl
- group
- compound
- halo
- formula
- Prior art date
Links
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Classifications
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
- C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
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- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
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- Endocrinology (AREA)
- Neurology (AREA)
- Reproductive Health (AREA)
- Orthopedic Medicine & Surgery (AREA)
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- Psychiatry (AREA)
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- Diabetes (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Pregnancy & Childbirth (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US68091105P | 2005-05-13 | 2005-05-13 | |
| PCT/US2006/018061 WO2006124447A2 (en) | 2005-05-13 | 2006-05-10 | Substituted n-arylpyrrolidines as selective androgen receptor modulators |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2007014053A true MX2007014053A (es) | 2008-02-05 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2007014053A MX2007014053A (es) | 2005-05-13 | 2006-05-10 | N-arilpirrolidinas substituidas como moduladores selectivos de receptor de androgeno. |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US7807691B2 (OSRAM) |
| EP (1) | EP1891038B1 (OSRAM) |
| JP (1) | JP5089578B2 (OSRAM) |
| CN (1) | CN101175747B (OSRAM) |
| AT (1) | ATE412647T1 (OSRAM) |
| AU (1) | AU2006247738A1 (OSRAM) |
| BR (1) | BRPI0610183A2 (OSRAM) |
| CA (1) | CA2608419A1 (OSRAM) |
| CY (1) | CY1108690T1 (OSRAM) |
| DE (1) | DE602006003432D1 (OSRAM) |
| DK (1) | DK1891038T3 (OSRAM) |
| ES (1) | ES2314922T3 (OSRAM) |
| MX (1) | MX2007014053A (OSRAM) |
| PL (1) | PL1891038T3 (OSRAM) |
| PT (1) | PT1891038E (OSRAM) |
| SI (1) | SI1891038T1 (OSRAM) |
| WO (1) | WO2006124447A2 (OSRAM) |
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| US8592452B2 (en) * | 2005-08-01 | 2013-11-26 | Takeda Pharmaceutical Company Limited | Cyclic amine compound |
| CA2670976C (en) | 2006-11-30 | 2015-01-27 | Atsushi Hasuoka | Cyclic amine compound |
| TW200831080A (en) * | 2006-12-15 | 2008-08-01 | Irm Llc | Compounds and compositions as inhibitors of cannabinoid receptor 1 activity |
| KR20100049644A (ko) | 2007-08-07 | 2010-05-12 | 다케다 야쿠힌 고교 가부시키가이샤 | 안드로겐 수용체 조절제로서의 피롤리딘-2-온 유도체 |
| ES2413504T3 (es) | 2007-12-21 | 2013-07-16 | Ligand Pharmaceuticals Inc. | Moduladores selectivos del receptor de andrógeno (SARM) y usos de los mismos |
| US8268872B2 (en) | 2008-02-22 | 2012-09-18 | Radius Health, Inc. | Selective androgen receptor modulators |
| US8067448B2 (en) | 2008-02-22 | 2011-11-29 | Radius Health, Inc. | Selective androgen receptor modulators |
| WO2009131196A1 (ja) * | 2008-04-24 | 2009-10-29 | 武田薬品工業株式会社 | 置換ピロリジン誘導体およびその用途 |
| WO2009133861A1 (ja) * | 2008-04-28 | 2009-11-05 | 武田薬品工業株式会社 | 環状アミン化合物 |
| MX338831B (es) | 2010-02-04 | 2016-05-03 | Radius Health Inc | Moduladores selectivos de receptores de androgenos. |
| SI2568806T1 (sl) | 2010-05-12 | 2016-09-30 | Radius Health, Inc. | Režimi zdravljenja |
| US8642632B2 (en) | 2010-07-02 | 2014-02-04 | Radius Health, Inc. | Selective androgen receptor modulators |
| AU2011312490B2 (en) | 2010-09-28 | 2015-06-25 | Radius Pharmaceuticals, Inc. | Selective androgen receptor modulators |
| JP5959541B2 (ja) * | 2011-02-25 | 2016-08-02 | ノバルティス アーゲー | Ｔｒｋ阻害剤としてのピラゾロ［１，５−ａ］ピリジン |
| AR088082A1 (es) * | 2011-10-13 | 2014-05-07 | Lilly Co Eli | Moduladores selectivos del receptor androgeno |
| EP3251674A3 (en) * | 2012-11-16 | 2018-02-21 | BioCryst Pharmaceuticals, Inc. | Antiviral azasugar-containing nucleosides |
| US9421264B2 (en) | 2014-03-28 | 2016-08-23 | Duke University | Method of treating cancer using selective estrogen receptor modulators |
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| US20190375732A1 (en) | 2018-05-14 | 2019-12-12 | David Hung | Anti-cancer nuclear hormone receptor-targeting compounds |
| BR112020021921A2 (pt) | 2018-05-17 | 2021-01-26 | Forma Therapeutics, Inc. | compostos bicíclicos fundidos úteis como inibidores de peptidase 30 específica de ubiquitina |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5411981A (en) * | 1991-01-09 | 1995-05-02 | Roussel Uclaf | Phenylimidazolidines having antiandrogenic activity |
| FR2693461B1 (fr) * | 1992-07-08 | 1994-09-02 | Roussel Uclaf | Nouvelles phénylimidazolidines substituées, leur procédé de préparation, leur application comme médicaments et les compositions pharmaceutiques les renfermant. |
| FR2671348B1 (fr) * | 1991-01-09 | 1993-03-26 | Roussel Uclaf | Nouvelles phenylimidazolidines, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant. |
| US6887870B1 (en) | 1999-10-12 | 2005-05-03 | Bristol-Myers Squibb Company | Heterocyclic sodium/proton exchange inhibitors and method |
| WO2004016576A1 (ja) | 2002-08-12 | 2004-02-26 | Takeda Pharmaceutical Company Limited | 縮合ベンゼン誘導体および用途 |
| AU2003285952A1 (en) * | 2002-10-21 | 2004-05-13 | Irm Llc | Pyrrolidones with anti-hiv activity |
| WO2005000795A2 (en) * | 2003-06-10 | 2005-01-06 | Smithkline Beecham Corporation | Aniline derivatived androgen-, glucocorticoid-, mineralcorticoid- and progesterone- receptor modulators |
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- 2006-05-10 WO PCT/US2006/018061 patent/WO2006124447A2/en not_active Ceased
- 2006-05-10 ES ES06759481T patent/ES2314922T3/es active Active
- 2006-05-10 AT AT06759481T patent/ATE412647T1/de active
- 2006-05-10 BR BRPI0610183-6A patent/BRPI0610183A2/pt not_active IP Right Cessation
- 2006-05-10 MX MX2007014053A patent/MX2007014053A/es active IP Right Grant
- 2006-05-10 SI SI200630177T patent/SI1891038T1/sl unknown
- 2006-05-10 CA CA002608419A patent/CA2608419A1/en not_active Abandoned
- 2006-05-10 CN CN2006800165544A patent/CN101175747B/zh not_active Expired - Fee Related
- 2006-05-10 DE DE602006003432T patent/DE602006003432D1/de active Active
- 2006-05-10 PL PL06759481T patent/PL1891038T3/pl unknown
- 2006-05-10 AU AU2006247738A patent/AU2006247738A1/en not_active Abandoned
- 2006-05-10 PT PT06759481T patent/PT1891038E/pt unknown
- 2006-05-10 EP EP06759481A patent/EP1891038B1/en not_active Not-in-force
- 2006-05-10 JP JP2008511312A patent/JP5089578B2/ja not_active Expired - Fee Related
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- 2009-01-09 CY CY20091100016T patent/CY1108690T1/el unknown
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| AU2006247738A1 (en) | 2006-11-23 |
| JP2008540554A (ja) | 2008-11-20 |
| US20080176864A1 (en) | 2008-07-24 |
| CY1108690T1 (el) | 2014-04-09 |
| BRPI0610183A2 (pt) | 2012-12-04 |
| CN101175747A (zh) | 2008-05-07 |
| PL1891038T3 (pl) | 2009-04-30 |
| WO2006124447A2 (en) | 2006-11-23 |
| EP1891038A2 (en) | 2008-02-27 |
| ATE412647T1 (de) | 2008-11-15 |
| CN101175747B (zh) | 2011-06-22 |
| ES2314922T3 (es) | 2009-03-16 |
| CA2608419A1 (en) | 2006-11-23 |
| DE602006003432D1 (de) | 2008-12-11 |
| SI1891038T1 (sl) | 2009-04-30 |
| JP5089578B2 (ja) | 2012-12-05 |
| DK1891038T3 (da) | 2009-01-19 |
| PT1891038E (pt) | 2008-12-02 |
| US7807691B2 (en) | 2010-10-05 |
| WO2006124447A3 (en) | 2007-03-29 |
| EP1891038B1 (en) | 2008-10-29 |
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