MX2007009577A - Metodos para predecir respuesta terapeutica en dermatitis atopica a antagonistas del il-31. - Google Patents

Metodos para predecir respuesta terapeutica en dermatitis atopica a antagonistas del il-31.

Info

Publication number
MX2007009577A
MX2007009577A MX2007009577A MX2007009577A MX2007009577A MX 2007009577 A MX2007009577 A MX 2007009577A MX 2007009577 A MX2007009577 A MX 2007009577A MX 2007009577 A MX2007009577 A MX 2007009577A MX 2007009577 A MX2007009577 A MX 2007009577A
Authority
MX
Mexico
Prior art keywords
methods
predicting
atopic dermatitis
therpeutic
antagonists
Prior art date
Application number
MX2007009577A
Other languages
English (en)
Spanish (es)
Inventor
Jane A Gross
Janine Bilsborough
Donald Y M Leung
Original Assignee
Zymogenetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zymogenetics Inc filed Critical Zymogenetics Inc
Publication of MX2007009577A publication Critical patent/MX2007009577A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
    • A61K49/0008—Screening agents using (non-human) animal models or transgenic animal models or chimeric hosts, e.g. Alzheimer disease animal model, transgenic model for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/006—Biological staining of tissues in vivo, e.g. methylene blue or toluidine blue O administered in the buccal area to detect epithelial cancer cells, dyes used for delineating tissues during surgery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5047—Cells of the immune system
    • G01N33/505—Cells of the immune system involving T-cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • G01N33/6869—Interleukin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6881—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Toxicology (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Oncology (AREA)
  • Virology (AREA)
MX2007009577A 2005-02-14 2006-02-14 Metodos para predecir respuesta terapeutica en dermatitis atopica a antagonistas del il-31. MX2007009577A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US65311405P 2005-02-14 2005-02-14
US71676205P 2005-09-13 2005-09-13
US74995205P 2005-12-13 2005-12-13
PCT/US2006/005328 WO2006088956A2 (en) 2005-02-14 2006-02-14 Methods of predicting therpeutic response in atopic dermatitis to il-31 antagonists

Publications (1)

Publication Number Publication Date
MX2007009577A true MX2007009577A (es) 2008-01-30

Family

ID=36685803

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2007009577A MX2007009577A (es) 2005-02-14 2006-02-14 Metodos para predecir respuesta terapeutica en dermatitis atopica a antagonistas del il-31.
MX2007009471A MX2007009471A (es) 2005-02-14 2006-02-14 Metodos de tratamiento de enfermedades que son mediadas por las celulas positivas al antigeno del linfocito cutaneo.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2007009471A MX2007009471A (es) 2005-02-14 2006-02-14 Metodos de tratamiento de enfermedades que son mediadas por las celulas positivas al antigeno del linfocito cutaneo.

Country Status (8)

Country Link
US (11) US20060188500A1 (enExample)
EP (2) EP1856150A2 (enExample)
JP (2) JP4927762B2 (enExample)
AU (2) AU2006214325B2 (enExample)
CA (2) CA2595939C (enExample)
IL (3) IL184734A (enExample)
MX (2) MX2007009577A (enExample)
WO (2) WO2006088955A2 (enExample)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1188830B1 (en) 1999-06-02 2010-01-20 Chugai Seiyaku Kabushiki Kaisha Novel hemopoietin receptor protein ,nr10
EP1221482B1 (en) 1999-09-27 2005-12-28 Chugai Seiyaku Kabushiki Kaisha Hemopoietin receptor protein, nr12
DK1476541T3 (da) 2002-01-18 2008-11-03 Zymogenetics Inc Cytokin (zcytor17-ligand)
US10080779B2 (en) 2004-12-15 2018-09-25 Universite D'angers Method for increasing the expression of anti-microbial peptides by keratinocytes comprising administering a composition comprising IL-17, TNF-alpha and OSM
US20060228329A1 (en) * 2005-01-28 2006-10-12 Brady Lowell J Homogeneous preparations of IL-31
CA2595939C (en) 2005-02-14 2014-08-19 Zymogenetics Inc. Methods of predicting therpeutic response in atopic dermatitis to il-31 antagonists
US20060182743A1 (en) 2005-02-14 2006-08-17 Janine Bilsborough Methods of treating skin disorders using an IL-31RA antagonist
JP5065253B2 (ja) 2005-05-06 2012-10-31 ザイモジェネティクス， インコーポレイテッド Ｉｌ−３１モノクローナル抗体とその使用法
US8101183B2 (en) 2005-05-06 2012-01-24 Zymogentics, Inc. Variable region sequences of IL-31 monoclonal antibodies
US20130216542A1 (en) 2005-05-06 2013-08-22 Zymogenetics, Inc. Variable region sequences of il-31 monoclonal antibodies and methods of use
JP2009528264A (ja) * 2006-01-10 2009-08-06 ザイモジェネティクス，インコーポレイティド Ｉｌ−３１アンタゴニストを用いて神経組織における疼痛及び炎症を治療する方法
AU2007255753B2 (en) 2006-06-08 2013-01-17 Chugai Seiyaku Kabushiki Kaisha Preventive or remedy for inflammatory disease
RU2009111884A (ru) * 2006-09-01 2010-10-10 Займоджинетикс, Инк. (Us) Последовательности вариабельных областей моноклональных антител против il-31 и способы использования
AU2008204823A1 (en) * 2007-01-10 2008-07-17 Zymogenetics, Inc Methods of using IL-31 to treat airway hyper-responsiveness and asthma
RU2596397C2 (ru) 2007-12-05 2016-09-10 Чугаи Сейяку Кабусики Кайся Терапевтическое средство от зуда
ES2660036T3 (es) 2007-12-07 2018-03-20 Zymogenetics, Inc. Moléculas de anticuerpo humanizadas específicas para IL-31
US8790651B2 (en) 2011-07-21 2014-07-29 Zoetis Llc Interleukin-31 monoclonal antibody
WO2014208645A1 (ja) * 2013-06-28 2014-12-31 中外製薬株式会社 そう痒を伴う疾患に罹患した患者のｉｌ－３１アンタゴニストによる治療に対する応答を予測する方法
MA40824A (fr) * 2014-10-22 2017-08-29 Saiba Gmbh Particules de cmv de type virus modifié
FI3284480T3 (fi) 2015-04-14 2025-09-11 Chugai Pharmaceutical Co Ltd IL-31-antagonistia vaikuttavana ainesosana sisältävä farmaseuttinen koostumus atooppisen ihottuman ehkäisemiseksi ja/tai hoitamiseksi
BR112017022101A2 (pt) * 2015-04-14 2018-07-31 Chugai Seiyaku Kabushiki Kaisha composição farmacêutica para prevenção e/ou tratamento de dermatite atópica contendo antagonista de il-31 como ingrediente ativo
US10060273B2 (en) 2015-04-15 2018-08-28 United Technologies Corporation System and method for manufacture of abrasive coating
WO2018156180A1 (en) 2017-02-24 2018-08-30 Kindred Biosciences, Inc. Anti-il31 antibodies for veterinary use
KR102828306B1 (ko) 2018-03-16 2025-07-01 조에티스 서비시즈 엘엘씨 수의학적 용도를 위한 인터류킨-31 단클론성 항체
BR112020017715A2 (pt) 2018-03-16 2020-12-29 Zoetis Services Llc Vacinas de peptídeo contra interleucina-31
US20210054085A1 (en) * 2018-04-25 2021-02-25 Kiniksa Pharmaceuticals, Ltd. Treatment of skin diseases or disorders by delivery of anti-osmrb antibody
CN112190708B (zh) * 2019-07-08 2023-09-05 上海交通大学医学院附属瑞金医院 趋化因子受体ccr6抑制剂在预防银屑病复发中的新应用
RU2707181C1 (ru) * 2019-08-15 2019-11-25 федеральное государственное бюджетное образовательное учреждение высшего образования "Башкирский государственный медицинский университет" Министерства здравоохранения Российской Федерации Способ прогнозирования степени тяжести течения пруриго методом определения уровня концентрации триптазы в крови
IL293099B2 (en) 2019-11-20 2025-07-01 Chugai Pharmaceutical Co Ltd Antibody-containing preparation
KR102392954B1 (ko) * 2020-02-11 2022-05-02 연세대학교 산학협력단 아토피 피부염 동물 모델인 아바타마우스의 제조 방법 및 그의 용도
CA3189847A1 (en) 2020-09-01 2022-03-10 Naoki Fukazawa Pharmaceutical composition for prevention and/or treatment of dialysis pruritus containing il-31 antagonist as active ingredient

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5792850A (en) * 1996-05-23 1998-08-11 Zymogenetics, Inc. Hematopoietic cytokine receptor
JPWO2003024484A1 (ja) 2001-09-14 2004-12-24 小野薬品工業株式会社 掻痒症治療剤
EP2338910B1 (en) * 2002-01-18 2015-07-08 ZymoGenetics, Inc. Cytokine receptor Zcytor17 multimers
DK1476541T3 (da) 2002-01-18 2008-11-03 Zymogenetics Inc Cytokin (zcytor17-ligand)
PL369936A1 (en) 2002-02-22 2005-05-02 Taisho Pharmaceutical Co, Ltd. Antipruritics
JP2004219390A (ja) * 2002-02-22 2004-08-05 Taisho Pharmaceut Co Ltd アトピー性皮膚炎に対し鎮痒効果を有する薬物の評価方法
JP2004107209A (ja) * 2002-09-13 2004-04-08 Nippon Oruganon Kk 掻痒治療薬
JP4503942B2 (ja) * 2003-06-11 2010-07-14 大正製薬株式会社 止痒剤
WO2006000020A1 (en) 2004-06-29 2006-01-05 European Nickel Plc Improved leaching of base metals
US20060228329A1 (en) 2005-01-28 2006-10-12 Brady Lowell J Homogeneous preparations of IL-31
US20060182743A1 (en) * 2005-02-14 2006-08-17 Janine Bilsborough Methods of treating skin disorders using an IL-31RA antagonist
CA2595939C (en) 2005-02-14 2014-08-19 Zymogenetics Inc. Methods of predicting therpeutic response in atopic dermatitis to il-31 antagonists
US8101183B2 (en) 2005-05-06 2012-01-24 Zymogentics, Inc. Variable region sequences of IL-31 monoclonal antibodies
JP5065253B2 (ja) * 2005-05-06 2012-10-31 ザイモジェネティクス， インコーポレイテッド Ｉｌ−３１モノクローナル抗体とその使用法
JP5018481B2 (ja) * 2005-09-28 2012-09-05 コニカミノルタアドバンストレイヤー株式会社 射出成形装置
JP2009528264A (ja) * 2006-01-10 2009-08-06 ザイモジェネティクス，インコーポレイティド Ｉｌ−３１アンタゴニストを用いて神経組織における疼痛及び炎症を治療する方法
TW200801513A (en) 2006-06-29 2008-01-01 Fermiscan Australia Pty Ltd Improved process
RU2009111884A (ru) * 2006-09-01 2010-10-10 Займоджинетикс, Инк. (Us) Последовательности вариабельных областей моноклональных антител против il-31 и способы использования
AU2008204823A1 (en) 2007-01-10 2008-07-17 Zymogenetics, Inc Methods of using IL-31 to treat airway hyper-responsiveness and asthma
ES2660036T3 (es) * 2007-12-07 2018-03-20 Zymogenetics, Inc. Moléculas de anticuerpo humanizadas específicas para IL-31

Also Published As

Publication number Publication date
WO2006088955A3 (en) 2006-11-16
MX2007009471A (es) 2008-02-15
US20110212093A1 (en) 2011-09-01
AU2006214326B2 (en) 2011-09-29
US20100266600A1 (en) 2010-10-21
IL184776A (en) 2014-06-30
EP1856150A2 (en) 2007-11-21
US20190040125A1 (en) 2019-02-07
IL184734A0 (en) 2007-12-03
JP4927762B2 (ja) 2012-05-09
US20060188499A1 (en) 2006-08-24
EP1856539B1 (en) 2015-10-21
US20130203070A1 (en) 2013-08-08
US7723048B2 (en) 2010-05-25
US20090092999A1 (en) 2009-04-09
US20060188500A1 (en) 2006-08-24
US8435745B2 (en) 2013-05-07
CA2595939C (en) 2014-08-19
US20130177563A1 (en) 2013-07-11
US20090280121A1 (en) 2009-11-12
US20170096484A1 (en) 2017-04-06
AU2006214325A1 (en) 2006-08-24
WO2006088956A3 (en) 2007-01-18
WO2006088955A2 (en) 2006-08-24
IL219145A0 (en) 2012-06-28
US8388964B2 (en) 2013-03-05
EP1856539A2 (en) 2007-11-21
AU2006214326A1 (en) 2006-08-24
JP2008530138A (ja) 2008-08-07
CA2595877A1 (en) 2006-08-24
US20160024201A1 (en) 2016-01-28
US8926957B2 (en) 2015-01-06
AU2006214325B2 (en) 2012-04-05
WO2006088956A2 (en) 2006-08-24
JP2008530137A (ja) 2008-08-07
CA2595939A1 (en) 2006-08-24
IL184734A (en) 2012-04-30
IL184776A0 (en) 2007-12-03

Similar Documents

Publication Publication Date Title
MX2007009577A (es) Metodos para predecir respuesta terapeutica en dermatitis atopica a antagonistas del il-31.
SG155054A1 (en) Human anti- neutralizing antibodies as selective pathway inhibitors
TW200716676A (en) Therapeutic human anti-IL-1R1 monoclonal antibody
JP2008530138A5 (enExample)
MX2009009283A (es) Anticuerpos anti-interleuquina -23r de ingenieria.
CY1112912T1 (el) Τροποποιημενα αντισωματα αντι-ιl-23ρ19
MXPA06014510A (es) Composiciones y metodos para tratar trastornos inflamatorios.
MXPA05008648A (es) Usos y formulaciones para la aplicacion transdermica o transmucosa de agentes activos.
TW200732347A (en) VEGF analogs and methods of use
NO341586B1 (no) Fremgangsmåte for valg av et anti-naturlig drepe cellereseptor (NKR) antistoff
TW200621801A (en) Antibody molecules having specificity for human IL-17
MX353143B (es) Marcadores biologicos y metodos para pronosticar respuesta a antagonistas de celulas b.
JOP20080381B1 (ar) بروتينات مرتبطة بمولدات مضادات تتفاعل مع بروبروتين كونفيرتاز سيتيليزين ككسين من النوع 9 (pcsk9)
MY144906A (en) Human antibodies against il13 and therapeutic uses
NZ710459A (en) Therapeutic applications of activation of human antigen-presenting cells through dectin-1
TW200728466A (en) Antibody molecules having specificity for human IL-6
MA31838B1 (fr) Anticorps se liant à l'il-4 et/ou à l'il-3 et leurs utilisations
MA31312B1 (fr) Anticorps anti-ige apoptopiques
MX2010001111A (es) Mutantes mcp-1 que antagonizan glicosaminoglicano y metodos para utilizar los mismos.
TW200637574A (en) Treatment method
IN2014CN04645A (enExample)
DE602007008859D1 (de) Benzoimidazol-2-yl pyridine als modulatoren des histamin-h4-rezeptors
TNSN07036A1 (en) Human monoclonal antibodies against human il-4
MA33381B1 (fr) Proteine de liaison a il-13
EP4265267A3 (en) Peptides for modulating t-cell activity and uses thereof

Legal Events

Date Code Title Description
FG Grant or registration