ME02412B - Spirocyclische isoxazolinderivate als antiparasitika - Google Patents
Spirocyclische isoxazolinderivate als antiparasitikaInfo
- Publication number
- ME02412B ME02412B MEP-2016-125A MEP2016125A ME02412B ME 02412 B ME02412 B ME 02412B ME P2016125 A MEP2016125 A ME P2016125A ME 02412 B ME02412 B ME 02412B
- Authority
- ME
- Montenegro
- Prior art keywords
- antiparasitic agents
- isoxazoline derivatives
- spirocyclic isoxazoline
- spirocyclic
- derivatives
- Prior art date
Links
- 239000003096 antiparasitic agent Substances 0.000 title 1
- 229940125687 antiparasitic agent Drugs 0.000 title 1
- 150000002547 isoxazolines Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- C07D491/107—Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N53/00—Biocides, pest repellants or attractants, or plant growth regulators containing cyclopropane carboxylic acids or derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/14—Ectoparasiticides, e.g. scabicides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Plant Pathology (AREA)
- Pest Control & Pesticides (AREA)
- Dentistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Agronomy & Crop Science (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161451256P | 2011-03-10 | 2011-03-10 | |
US201161489913P | 2011-05-25 | 2011-05-25 | |
US201161490804P | 2011-05-27 | 2011-05-27 | |
PCT/IB2012/050842 WO2012120399A1 (en) | 2011-03-10 | 2012-02-23 | Spirocyclic isoxazoline derivatives as antiparasitic agents |
EP12709376.3A EP2683723B1 (de) | 2011-03-10 | 2012-02-23 | Spirocyclische isoxazolinderivate als antiparasitika |
Publications (1)
Publication Number | Publication Date |
---|---|
ME02412B true ME02412B (de) | 2016-09-20 |
Family
ID=45852624
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MEP-2016-125A ME02412B (de) | 2011-03-10 | 2012-02-23 | Spirocyclische isoxazolinderivate als antiparasitika |
Country Status (26)
Country | Link |
---|---|
US (1) | US8466115B2 (de) |
EP (1) | EP2683723B1 (de) |
JP (1) | JP5806743B2 (de) |
KR (1) | KR101565853B1 (de) |
CN (1) | CN103517907B (de) |
AR (1) | AR085649A1 (de) |
AU (1) | AU2012226475C1 (de) |
BR (1) | BR112013023068B8 (de) |
CA (1) | CA2828397C (de) |
CL (1) | CL2013002516A1 (de) |
CO (1) | CO6761337A2 (de) |
CY (1) | CY1117987T1 (de) |
ES (1) | ES2585555T3 (de) |
HK (1) | HK1190393A1 (de) |
HR (1) | HRP20160601T1 (de) |
HU (1) | HUE029810T2 (de) |
ME (1) | ME02412B (de) |
MX (1) | MX2013010336A (de) |
PL (1) | PL2683723T3 (de) |
PT (1) | PT2683723T (de) |
RS (1) | RS54860B1 (de) |
RU (1) | RU2566083C3 (de) |
SI (1) | SI2683723T1 (de) |
UY (1) | UY33943A (de) |
WO (1) | WO2012120399A1 (de) |
ZA (1) | ZA201306817B (de) |
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WO2014036056A1 (en) * | 2012-08-31 | 2014-03-06 | Zoetis Llc | Crystalline forms of 1-(5'-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-3'h-spiro[azetidine-3,1'-isobenzofuran]-1-yl)-2-(methylsulfonyl)ethanone |
CA2882199A1 (en) | 2012-09-04 | 2014-03-13 | Zoetis Llc | Spirocyclic isoxazoline derivatives for treatment of sea lice |
WO2014039484A1 (en) * | 2012-09-07 | 2014-03-13 | Zoetis Llc | Spirocyclic isoxazolines as antiparasitic agents |
US9226928B2 (en) * | 2012-09-07 | 2016-01-05 | Zoetis Services Llc | Spirocyclic isoxazoline parasiticidal combinations |
CN104603139B (zh) | 2012-09-07 | 2016-12-07 | 硕腾服务有限责任公司 | 作为抗寄生虫剂的螺环衍生物 |
CN104918944B (zh) * | 2012-11-21 | 2017-05-10 | 硕腾服务有限责任公司 | 螺环异噁唑啉衍生物的合成 |
CA2900029C (en) | 2013-02-06 | 2021-03-02 | Bayer Cropscience Aktiengesellschaft | Halogen-substituted pyrazol derivatives as pest-control agents |
US20160081986A1 (en) * | 2013-05-20 | 2016-03-24 | Zoetis Services Llc | Long-acting spiro-isoxazoline antiparasitic compositions |
WO2015048371A1 (en) | 2013-09-30 | 2015-04-02 | Zoetis Llc | Long-acting spiro-isoxazoline formulations |
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RU2688919C1 (ru) | 2013-12-20 | 2019-05-23 | Интервет Интернэшнл Б.В. | Изоксазолиновые композиции и их применение в провилактике или лечении паразитарных инвазий животных |
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MX2016013573A (es) | 2014-04-17 | 2017-02-13 | Merial Inc | Uso de compuestos de malononitrilo para proteger animales de parasitos. |
RU2017104717A (ru) | 2014-07-15 | 2018-08-15 | Байер Энимэл Хельс ГмбХ | Арилтриазолилпиридины в качестве средств для борьбы с вредителями |
WO2016069983A1 (en) | 2014-10-31 | 2016-05-06 | Merial, Inc. | Parasiticidal composition comprising fipronil |
JP6706262B2 (ja) * | 2014-12-22 | 2020-06-03 | インターベット インターナショナル ベー. フェー. | 毛包虫症治療のためのイソオキサゾリン化合物の使用 |
JP2018509463A (ja) | 2015-01-16 | 2018-04-05 | アビスタ ファーマ ソリューションズ,インコーポレーテッド | 抗寄生生物化合物 |
UY36570A (es) | 2015-02-26 | 2016-10-31 | Merial Inc | Formulaciones inyectables de acción prolongada que comprenden un agente activo isoxazolina, métodos y usos de las mismas |
SG11201708068PA (en) | 2015-04-08 | 2017-10-30 | Merial Inc | Extended release injectable formulations comprising an isoxazoline active agent, methods and uses thereof |
JP7045191B2 (ja) | 2015-05-20 | 2022-03-31 | ベーリンガー インゲルハイム アニマル ヘルス ユーエスエイ インコーポレイテッド | 駆虫性デプシペプチド化合物 |
UY37137A (es) | 2016-02-24 | 2017-09-29 | Merial Inc | Compuestos antiparasitarios de isoxazolina, formulaciones inyectables de acción prolongada que los comprenden, métodos y usos de los mismos |
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AU2019369659A1 (en) | 2018-10-29 | 2021-04-29 | Basf Se | Process for preparation of optically enriched aldol compounds |
WO2020094434A1 (en) | 2018-11-06 | 2020-05-14 | Basf Se | Process for preparation of optically enriched isoxazolines |
CN113260419A (zh) | 2018-11-20 | 2021-08-13 | 勃林格殷格翰动物保健美国公司 | 吲唑基氰基乙基氨基化合物、其组合物、其制备方法和其使用方法 |
IL283448B1 (en) | 2018-12-04 | 2024-07-01 | Basf Se | Process for preparing 5-bromo-3,1-dichloro-2-fluoro-benzene |
WO2020150032A1 (en) | 2019-01-16 | 2020-07-23 | Boehringer Ingelheim Animal Health USA Inc. | Topical compositions comprising a neonicotinoid and a macrocyclic lactone, methods and uses thereof |
CA3133100A1 (en) | 2019-03-19 | 2020-09-24 | Boehringer Ingelheim Animal Health USA Inc. | Anthelmintic aza-benzothiophene and aza-benzofuran compounds |
AR119162A1 (es) | 2019-06-18 | 2021-12-01 | Idorsia Pharmaceuticals Ltd | Derivados de piridin-3-ilo |
MX2022007455A (es) * | 2019-12-18 | 2022-08-15 | Elanco Tiergesundheit Ag | Derivados de isoxazolina como plaguicidas. |
CN111253331B (zh) * | 2020-03-17 | 2022-03-08 | 南京林业大学 | 一种以二氢查尔酮为原料合成螺异噁唑啉的方法 |
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-
2012
- 2012-02-23 SI SI201230583A patent/SI2683723T1/sl unknown
- 2012-02-23 HU HUE12709376A patent/HUE029810T2/en unknown
- 2012-02-23 RS RS20160432A patent/RS54860B1/sr unknown
- 2012-02-23 WO PCT/IB2012/050842 patent/WO2012120399A1/en active Application Filing
- 2012-02-23 PL PL12709376T patent/PL2683723T3/pl unknown
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