MA38859A - Anticorps anti-c5 présentant une pharmacocinétique améliorée - Google Patents
Anticorps anti-c5 présentant une pharmacocinétique amélioréeInfo
- Publication number
- MA38859A MA38859A MA038859A MA38859A MA38859A MA 38859 A MA38859 A MA 38859A MA 038859 A MA038859 A MA 038859A MA 38859 A MA38859 A MA 38859A MA 38859 A MA38859 A MA 38859A
- Authority
- MA
- Morocco
- Prior art keywords
- antibodies
- improved pharmacokinetics
- complement
- anaphylatoxin
- eculizumab
- Prior art date
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Abstract
La présente invention concerne des anticorps qui sont utiles, entre autres, pour inhiber la fraction terminale du complément (par exemple l'assemblage et/ou l'activité du c5b -9 tcc) et l'inflammation médiée par l'anaphylatoxine c5a et, par conséquent, le traitement de troubles associés au complément. Les anticorps ont un certain nombre de propriétés améliorées par rapport à l'eculizumab, comprenant, par exemple, demi-vie sérique accrue dans un être humain.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201461949932P | 2014-03-07 | 2014-03-07 | |
PCT/US2015/019225 WO2015134894A1 (fr) | 2014-03-07 | 2015-03-06 | Anticorps anti-c5 présentant une pharmacocinétique améliorée |
Publications (2)
Publication Number | Publication Date |
---|---|
MA38859A true MA38859A (fr) | 2016-01-20 |
MA38859B1 MA38859B1 (fr) | 2017-01-31 |
Family
ID=52684742
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA050373A MA50373A (fr) | 2014-03-07 | 2015-03-06 | Anticorps anti-c5 présentant une pharmacocinétique améliorée |
MA38859A MA38859B1 (fr) | 2014-03-07 | 2015-03-06 | Anticorps anti-c5 présentant une pharmacocinétique améliorée |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA050373A MA50373A (fr) | 2014-03-07 | 2015-03-06 | Anticorps anti-c5 présentant une pharmacocinétique améliorée |
Country Status (29)
Country | Link |
---|---|
US (10) | US9079949B1 (fr) |
EP (3) | EP3594235A1 (fr) |
JP (5) | JP6112469B1 (fr) |
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