MA31516B1 - Modification de la production de glycoprotéine dans des plantes - Google Patents
Modification de la production de glycoprotéine dans des plantesInfo
- Publication number
- MA31516B1 MA31516B1 MA32504A MA32504A MA31516B1 MA 31516 B1 MA31516 B1 MA 31516B1 MA 32504 A MA32504 A MA 32504A MA 32504 A MA32504 A MA 32504A MA 31516 B1 MA31516 B1 MA 31516B1
- Authority
- MA
- Morocco
- Prior art keywords
- plant
- nucleotide sequence
- protein
- interest
- gnt1
- Prior art date
Links
- 102000003886 Glycoproteins Human genes 0.000 title 1
- 108090000288 Glycoproteins Proteins 0.000 title 1
- 230000004048 modification Effects 0.000 title 1
- 238000012986 modification Methods 0.000 title 1
- 239000002773 nucleotide Substances 0.000 abstract 4
- 125000003729 nucleotide group Chemical group 0.000 abstract 4
- 108090000623 proteins and genes Proteins 0.000 abstract 4
- 102000004169 proteins and genes Human genes 0.000 abstract 4
- 238000000034 method Methods 0.000 abstract 2
- 230000001105 regulatory effect Effects 0.000 abstract 2
- 101150112732 GNT1 gene Proteins 0.000 abstract 1
- 108010046068 N-Acetyllactosamine Synthase Proteins 0.000 abstract 1
- 102100023315 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase Human genes 0.000 abstract 1
- 108010056664 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase Proteins 0.000 abstract 1
- 230000004988 N-glycosylation Effects 0.000 abstract 1
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 230000003197 catalytic effect Effects 0.000 abstract 1
- 230000004186 co-expression Effects 0.000 abstract 1
- 230000005021 gait Effects 0.000 abstract 1
- 230000002194 synthesizing effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
- C12N15/8218—Antisense, co-suppression, viral induced gene silencing [VIGS], post-transcriptional induced gene silencing [PTGS]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
- C12N15/8245—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified carbohydrate or sugar alcohol metabolism, e.g. starch biosynthesis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
- C12N15/8258—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon for the production of oral vaccines (antigens) or immunoglobulins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1051—Hexosyltransferases (2.4.1)
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nutrition Science (AREA)
- Virology (AREA)
- Immunology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Enzymes And Modification Thereof (AREA)
- Cultivation Of Plants (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US94434407P | 2007-06-15 | 2007-06-15 | |
| PCT/CA2008/001139 WO2008151440A1 (en) | 2007-06-15 | 2008-06-13 | Modifying glycoprotein production in plants |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA31516B1 true MA31516B1 (fr) | 2010-07-01 |
Family
ID=40129187
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA32504A MA31516B1 (fr) | 2007-06-15 | 2010-01-12 | Modification de la production de glycoprotéine dans des plantes |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US20110008837A1 (https=) |
| EP (1) | EP2155880B1 (https=) |
| JP (1) | JP5783720B2 (https=) |
| KR (2) | KR101385050B1 (https=) |
| CN (3) | CN104962579A (https=) |
| AU (1) | AU2008261527C1 (https=) |
| BR (1) | BRPI0812538B1 (https=) |
| CA (2) | CA2795379A1 (https=) |
| DK (1) | DK2155880T3 (https=) |
| EG (1) | EG26600A (https=) |
| ES (1) | ES2624776T3 (https=) |
| HU (1) | HUE031698T2 (https=) |
| IL (1) | IL202568A (https=) |
| MA (1) | MA31516B1 (https=) |
| MX (1) | MX2009013665A (https=) |
| NZ (2) | NZ598417A (https=) |
| PL (1) | PL2155880T3 (https=) |
| PT (1) | PT2155880T (https=) |
| RU (2) | RU2499053C2 (https=) |
| SG (1) | SG185249A1 (https=) |
| SI (1) | SI2155880T1 (https=) |
| TN (1) | TN2009000512A1 (https=) |
| WO (1) | WO2008151440A1 (https=) |
| ZA (1) | ZA201000207B (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2615372A1 (en) | 2007-07-13 | 2009-01-13 | Marc-Andre D'aoust | Influenza virus-like particles (vlps) comprising hemagglutinin |
| EP2238253B1 (en) | 2007-11-27 | 2012-09-12 | Medicago Inc. | Recombinant influenza virus-like particles (vlps) produced in transgenic plants expressing hemagglutinin |
| DK2294202T3 (en) | 2008-07-08 | 2015-08-31 | Medicago Inc | SOLUBLE RECOMBINANT INFLUENZA ANTIGENES |
| MX370690B (es) | 2008-07-18 | 2019-12-19 | Medicago Inc | Epitopo de inmunizacion de nuevo virus de la influenza. |
| HRP20180706T1 (hr) | 2009-06-24 | 2018-06-01 | Medicago Inc. | Kimerna gripa nalik čestici koja sadrži hemaglutinin |
| PH12012500565B1 (en) | 2009-09-22 | 2018-01-12 | Medicago Inc | Method of preparing plant-derived proteins |
| TWI620816B (zh) | 2011-03-23 | 2018-04-11 | 苜蓿股份有限公司 | 植物衍生蛋白回收方法 |
| CA2839932C (en) * | 2011-06-07 | 2022-07-05 | Ibio, Inc. | In vivo de-glycosylation of recombinant proteins by co-expression with pngase f |
| EP2551348B1 (en) | 2011-07-29 | 2014-09-24 | Icon Genetics GmbH | Production of galactosylated N-glycans in plants |
| AU2012315421C1 (en) | 2011-09-30 | 2019-12-05 | Aramis Biotechnologies Inc. | Increasing virus-like particle yield in plants |
| KR20130125337A (ko) * | 2012-05-08 | 2013-11-18 | 경상대학교산학협력단 | 고-만노오스형 n-글라이칸을 생산하는 식물체 및 이를 이용한 고-만노오스형 n-글라이칸의 생산방법 |
| US12467058B2 (en) | 2013-03-28 | 2025-11-11 | Aramis Biotechnologies Inc. | Influenza virus-like particle production in plants |
| CN112592389A (zh) | 2013-03-28 | 2021-04-02 | 莫迪卡戈公司 | 植物中流感样病毒颗粒的产生 |
| CA2954759C (en) | 2014-07-11 | 2021-09-14 | Medicago Inc. | Modifying protein production in plants |
| WO2016079739A2 (en) | 2014-11-20 | 2016-05-26 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Compositions and methods for producing polypeptides with a modified glycosylation pattern in plant cells |
| US11499160B2 (en) | 2016-12-01 | 2022-11-15 | Plantform Corporation | Transgenic plant with reduced fucosyltransferase and xylosyltransferase activity |
| EP3682012A1 (en) * | 2017-09-11 | 2020-07-22 | R. J. Reynolds Tobacco Company | Methods and compositions for increasing expression of genes of interest in a plant by co-expression with p21 |
| JP7566045B2 (ja) * | 2021-01-15 | 2024-10-11 | デンカ株式会社 | 栽培条件を決定する方法、及び目的タンパク質又は目的ペプチドの製造方法 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5312746A (en) * | 1993-01-08 | 1994-05-17 | Life Technologies, Inc. | Cloning and expressing restriction endonucleases and modification methylases from caryophanon |
| GB9524350D0 (en) * | 1995-11-29 | 1996-01-31 | Lynxvale Ltd | Enhancer-increased gene expression in plants |
| US5945326A (en) * | 1997-03-20 | 1999-08-31 | New England Biolabs, Inc. | Method for cloning and producing the Spel restriction endonuclease |
| ES2558160T3 (es) * | 1998-12-09 | 2016-02-02 | Phyton Holdings, Llc | Glicoproteínas que tienen glicosilación de tipo humano |
| MXPA02003455A (es) * | 1999-10-04 | 2002-10-23 | Medicago Inc | Promotor para regular la expresion de genes foraneos. |
| US7125978B1 (en) * | 1999-10-04 | 2006-10-24 | Medicago Inc. | Promoter for regulating expression of foreign genes |
| BR0014945A (pt) * | 1999-10-21 | 2004-08-31 | Monsanto Co | Modificação pós-traducional de proteìnas recombinantes produzidas em plantas |
| WO2001031044A1 (en) * | 1999-10-26 | 2001-05-03 | Id-Lelystad, Instituut Voor Dierhouderij En Diergezondheid B.V. | Gonadotrophins in plants |
| ATE478150T1 (de) * | 1999-10-26 | 2010-09-15 | Stichting Dienst Landbouwkundi | Säugetierartige glykosylierung in pflanzen |
| BRPI0206546B1 (pt) * | 2001-01-19 | 2015-07-21 | Phyton Holdings Llc | Método para a produção secretória de glicoproteína que tem cadeia de açúcar do tipo humana, usando célula vegetal |
| US20030035774A1 (en) | 2001-07-18 | 2003-02-20 | Adjei Akwete L. | Salt/ion pair medicinal aerosol formulation |
| EP2180044A1 (en) * | 2001-08-03 | 2010-04-28 | GlycArt Biotechnology AG | Antibody glycosylation variants having increased anti-body-dependent cellular cytotoxicity |
| AU2003219745B8 (en) * | 2002-02-13 | 2008-10-09 | Wisconsin Alumni Research Foundation | Signal for packaging of influenza virus vectors |
| CA2478297C (en) * | 2002-03-19 | 2013-05-14 | Plant Research International B.V. | Optimizing glycan processing in plants |
| KR101070518B1 (ko) * | 2002-03-19 | 2011-10-05 | 스티칭 디엔스트 랜드보위쿤디그 온데조에크 | 식물에서의 ｇｎｔⅲ 발현 |
| CN103540600B (zh) * | 2003-01-22 | 2017-12-01 | 罗氏格黎卡特股份公司 | 融合构建体及其用来生产Fc受体结合亲和性和效应子功能提高的抗体的用途 |
| CN1761746B (zh) * | 2003-01-22 | 2016-03-23 | 罗氏格黎卡特股份公司 | 融合构建体及其用来生产Fc受体结合亲和性和效应子功能提高的抗体的用途 |
| ATE473271T1 (de) * | 2003-05-05 | 2010-07-15 | Thompson Boyce Plant Res | Vektoren und zellen zur herstellung von aus transgenen pflanzen gewonnenen immunprotektiven zusammensetzungen |
| JP2006212019A (ja) * | 2004-04-30 | 2006-08-17 | National Institute Of Agrobiological Sciences | 植物を用いたユビキノン−１０の製造方法 |
-
2008
- 2008-06-13 DK DK08772802.8T patent/DK2155880T3/en active
- 2008-06-13 HU HUE08772802A patent/HUE031698T2/en unknown
- 2008-06-13 CA CA2795379A patent/CA2795379A1/en not_active Abandoned
- 2008-06-13 SI SI200831699A patent/SI2155880T1/sl unknown
- 2008-06-13 US US12/664,567 patent/US20110008837A1/en not_active Abandoned
- 2008-06-13 BR BRPI0812538-4A patent/BRPI0812538B1/pt not_active IP Right Cessation
- 2008-06-13 KR KR1020107000811A patent/KR101385050B1/ko not_active Expired - Fee Related
- 2008-06-13 NZ NZ598417A patent/NZ598417A/xx not_active IP Right Cessation
- 2008-06-13 CN CN201510364867.XA patent/CN104962579A/zh active Pending
- 2008-06-13 EP EP08772802.8A patent/EP2155880B1/en active Active
- 2008-06-13 CN CN2008801031743A patent/CN101918559A/zh active Pending
- 2008-06-13 NZ NZ581944A patent/NZ581944A/en unknown
- 2008-06-13 ES ES08772802.8T patent/ES2624776T3/es active Active
- 2008-06-13 RU RU2010101024/10A patent/RU2499053C2/ru active
- 2008-06-13 CN CN2013101091944A patent/CN103382487A/zh active Pending
- 2008-06-13 JP JP2010511461A patent/JP5783720B2/ja not_active Expired - Fee Related
- 2008-06-13 PT PT87728028T patent/PT2155880T/pt unknown
- 2008-06-13 WO PCT/CA2008/001139 patent/WO2008151440A1/en not_active Ceased
- 2008-06-13 AU AU2008261527A patent/AU2008261527C1/en not_active Ceased
- 2008-06-13 PL PL08772802T patent/PL2155880T3/pl unknown
- 2008-06-13 SG SG2012066486A patent/SG185249A1/en unknown
- 2008-06-13 KR KR1020137014893A patent/KR20130075787A/ko not_active Ceased
- 2008-06-13 MX MX2009013665A patent/MX2009013665A/es active IP Right Grant
- 2008-06-13 CA CA2700180A patent/CA2700180C/en active Active
-
2009
- 2009-12-07 IL IL202568A patent/IL202568A/en active IP Right Grant
- 2009-12-10 TN TNP2009000512A patent/TN2009000512A1/fr unknown
- 2009-12-14 EG EG2009121826A patent/EG26600A/en active
-
2010
- 2010-01-12 ZA ZA2010/00207A patent/ZA201000207B/en unknown
- 2010-01-12 MA MA32504A patent/MA31516B1/fr unknown
-
2013
- 2013-08-08 RU RU2013137208/10A patent/RU2013137208A/ru not_active Application Discontinuation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MA31516B1 (fr) | Modification de la production de glycoprotéine dans des plantes | |
| Sears et al. | Enzyme action in glycoprotein synthesis | |
| Willer et al. | O-mannosyl glycans: from yeast to novel associations with human disease | |
| Field et al. | Molecular cloning of eukaryotic glycoprotein and glycolipid glycosyltransferases: a survey | |
| Costa et al. | Glycosylation: impact, control and improvement during therapeutic protein production | |
| Butler et al. | The choice of mammalian cell host and possibilities for glycosylation engineering | |
| WO2007084922A3 (en) | Compositions and methods for humanization and optimization of n-glycans in plants | |
| JP2004528001A (ja) | インビトロにおけるフコシル化組換えグリコペプチド | |
| CN101679943A (zh) | 低温和/或低pH值在细胞培养中的使用 | |
| KR20220122699A (ko) | 고도로 시알릴화된 다량체 결합 분자 | |
| CN111954719A (zh) | 细胞培养物中产生的抗体的总去岩藻糖基化糖型 | |
| JP7835691B2 (ja) | 高シアル化免疫グロブリン | |
| Lim et al. | The Golgi CMP-sialic acid transporter: a new CHO mutant provides functional insights | |
| Ju et al. | Identification of core 1 O-glycan T-synthase from Caenorhabditis elegans | |
| Hombu et al. | Cellular and molecular engineering of glycan sialylation in heterologous systems | |
| Czlapinski et al. | Synthetic glycobiology: exploits in the Golgi compartment | |
| Maï et al. | Engineering a human-like glycosylation to produce therapeutic glycoproteins based on 6-linked sialylation in CHO cells | |
| AU2005237951A1 (en) | Method for expressing sialylated glycoproteins in mammalian cells and cells thereof | |
| Chang et al. | Novel zebrafish mono-α2, 8-sialyltransferase (ST8Sia VIII): An evolutionary perspective of α2, 8-sialylation | |
| Narimatsu | Recent progress in molecular cloning of glycosyltransferase genes of eukaryotes | |
| TR200000483T2 (tr) | Yabancı protein ifadesinin arttırılması için yöntem. | |
| CA3173252A1 (en) | Enzymes for sialylation of glycans | |
| De Vries et al. | Production of soluble human α3-fucosyltransferase (FucT VII) by membrane targeting and in vivo proteolysis | |
| Zheng et al. | A novel α1, 2-fucosyltransferase (CE2FT-2) in Caenorhabditis elegans generates H-type 3 glycan structures | |
| EP2598648B1 (en) | N-glycosylation in transformed phaeodactylum tricornutum |