CN104962579A - 修饰植物中的糖蛋白产生 - Google Patents

修饰植物中的糖蛋白产生 Download PDF

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Publication number
CN104962579A
CN104962579A CN201510364867.XA CN201510364867A CN104962579A CN 104962579 A CN104962579 A CN 104962579A CN 201510364867 A CN201510364867 A CN 201510364867A CN 104962579 A CN104962579 A CN 104962579A
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nucleotide sequence
plant
protein
sequence
seq
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Pending
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CN201510364867.XA
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Chinese (zh)
Inventor
马克-安德烈·德奥斯特
埃斯泰勒·马凯-布卢安
穆里尔·巴尔多
卡罗勒·比雷尔
卢瓦克·法耶
帕特里斯·勒鲁热
路易斯-菲利普·韦齐纳
韦罗妮克·戈莫尔德
斯特凡妮·阿奎
克里斯托夫·里韦
托马斯·帕卡莱特
克里斯托夫·苏鲁耶
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NATIONAL CENTER FOR SCIENTIFIC RESEARCH
Rouen, University of
Medicago Inc
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NATIONAL CENTER FOR SCIENTIFIC RESEARCH
Rouen, University of
Medicago Inc
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Application filed by NATIONAL CENTER FOR SCIENTIFIC RESEARCH, Rouen, University of, Medicago Inc filed Critical NATIONAL CENTER FOR SCIENTIFIC RESEARCH
Publication of CN104962579A publication Critical patent/CN104962579A/zh
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C12N15/8218—Antisense, co-suppression, viral induced gene silencing [VIGS], post-transcriptional induced gene silencing [PTGS]
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/8245—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified carbohydrate or sugar alcohol metabolism, e.g. starch biosynthesis
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • C12N15/8258—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon for the production of oral vaccines (antigens) or immunoglobulins
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)

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  • Health & Medical Sciences (AREA)
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  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
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  • Wood Science & Technology (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
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  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
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  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nutrition Science (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Cultivation Of Plants (AREA)
CN201510364867.XA 2007-06-15 2008-06-13 修饰植物中的糖蛋白产生 Pending CN104962579A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US94434407P 2007-06-15 2007-06-15
US60/944,344 2007-06-15
CN2008801031743A CN101918559A (zh) 2007-06-15 2008-06-13 修饰植物中的糖蛋白产生

Related Parent Applications (1)

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CN2008801031743A Division CN101918559A (zh) 2007-06-15 2008-06-13 修饰植物中的糖蛋白产生

Publications (1)

Publication Number Publication Date
CN104962579A true CN104962579A (zh) 2015-10-07

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Application Number Title Priority Date Filing Date
CN201510364867.XA Pending CN104962579A (zh) 2007-06-15 2008-06-13 修饰植物中的糖蛋白产生
CN2008801031743A Pending CN101918559A (zh) 2007-06-15 2008-06-13 修饰植物中的糖蛋白产生
CN2013101091944A Pending CN103382487A (zh) 2007-06-15 2008-06-13 修饰植物中的糖蛋白产生

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CN2008801031743A Pending CN101918559A (zh) 2007-06-15 2008-06-13 修饰植物中的糖蛋白产生
CN2013101091944A Pending CN103382487A (zh) 2007-06-15 2008-06-13 修饰植物中的糖蛋白产生

Country Status (24)

Country Link
US (1) US20110008837A1 (https=)
EP (1) EP2155880B1 (https=)
JP (1) JP5783720B2 (https=)
KR (2) KR101385050B1 (https=)
CN (3) CN104962579A (https=)
AU (1) AU2008261527C1 (https=)
BR (1) BRPI0812538B1 (https=)
CA (2) CA2795379A1 (https=)
DK (1) DK2155880T3 (https=)
EG (1) EG26600A (https=)
ES (1) ES2624776T3 (https=)
HU (1) HUE031698T2 (https=)
IL (1) IL202568A (https=)
MA (1) MA31516B1 (https=)
MX (1) MX2009013665A (https=)
NZ (2) NZ598417A (https=)
PL (1) PL2155880T3 (https=)
PT (1) PT2155880T (https=)
RU (2) RU2499053C2 (https=)
SG (1) SG185249A1 (https=)
SI (1) SI2155880T1 (https=)
TN (1) TN2009000512A1 (https=)
WO (1) WO2008151440A1 (https=)
ZA (1) ZA201000207B (https=)

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AU2009267769B2 (en) 2008-07-08 2015-07-16 Medicago Inc. Soluble recombinant influenza antigens
NZ590351A (en) 2008-07-18 2012-11-30 Medicago Inc HA1 domain totally or partially free of N-linked glycosylation operatively linked to a regulatory region
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KR101773431B1 (ko) 2009-09-22 2017-09-12 메디카고 인코포레이티드 식물-유래 ｖｌｐ의 제조방법
TWI620816B (zh) 2011-03-23 2018-04-11 苜蓿股份有限公司 植物衍生蛋白回收方法
WO2012170678A1 (en) * 2011-06-07 2012-12-13 Fraunhofer Usa, Inc. In vivo de-glycosylation of recombinant proteins by co-expression with pngase f
US9181532B2 (en) 2011-07-29 2015-11-10 Icon Genetics Gmbh Production of galactosylated N-glycans in plants
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KR20130125337A (ko) * 2012-05-08 2013-11-18 경상대학교산학협력단 고-만노오스형 n-글라이칸을 생산하는 식물체 및 이를 이용한 고-만노오스형 n-글라이칸의 생산방법
US12467058B2 (en) 2013-03-28 2025-11-11 Aramis Biotechnologies Inc. Influenza virus-like particle production in plants
ES2803508T3 (es) 2013-03-28 2021-01-27 Medicago Inc Producción de partículas similares al virus de la gripe en plantas
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111328347A (zh) * 2017-09-11 2020-06-23 R.J.雷诺兹烟草公司 通过与p21共表达来增加植物中感兴趣基因的表达的方法和组合物

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WO2008151440A4 (en) 2009-02-26
CA2795379A1 (en) 2008-12-18
MX2009013665A (es) 2010-06-02
AU2008261527B8 (en) 2014-04-24
JP5783720B2 (ja) 2015-09-24
WO2008151440A8 (en) 2010-03-04
HUE031698T2 (en) 2017-07-28
CA2700180A1 (en) 2008-12-18
NZ598417A (en) 2013-06-28
US20110008837A1 (en) 2011-01-13
CN101918559A (zh) 2010-12-15
IL202568A0 (en) 2011-08-01
SG185249A1 (en) 2012-11-29
KR101385050B1 (ko) 2014-05-13
CN103382487A (zh) 2013-11-06
MA31516B1 (fr) 2010-07-01
ZA201000207B (en) 2013-09-25
BRPI0812538A2 (pt) 2014-09-30
AU2008261527A8 (en) 2010-01-21
ES2624776T3 (es) 2017-07-17
PT2155880T (pt) 2016-11-18
EG26600A (en) 2014-03-23
RU2013137208A (ru) 2015-02-20
EP2155880A4 (en) 2010-08-04
SI2155880T1 (sl) 2017-03-31
AU2008261527B2 (en) 2014-04-10
WO2008151440A1 (en) 2008-12-18
BRPI0812538B1 (pt) 2021-03-16
IL202568A (en) 2015-02-26
AU2008261527C1 (en) 2014-09-04
DK2155880T3 (en) 2016-12-05
PL2155880T3 (pl) 2017-06-30
EP2155880B1 (en) 2016-08-10
TN2009000512A1 (en) 2011-03-31
NZ581944A (en) 2012-03-30
AU2008261527A1 (en) 2008-12-18
KR20100037602A (ko) 2010-04-09
RU2499053C2 (ru) 2013-11-20
KR20130075787A (ko) 2013-07-05
JP2010531136A (ja) 2010-09-24
EP2155880A1 (en) 2010-02-24
CA2700180C (en) 2013-01-29
RU2010101024A (ru) 2011-07-20

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Application publication date: 20151007