MA31422B1 - Composition pharmaceutique a liberation prolongee constituee de microparticules - Google Patents
Composition pharmaceutique a liberation prolongee constituee de microparticulesInfo
- Publication number
- MA31422B1 MA31422B1 MA32391A MA32391A MA31422B1 MA 31422 B1 MA31422 B1 MA 31422B1 MA 32391 A MA32391 A MA 32391A MA 32391 A MA32391 A MA 32391A MA 31422 B1 MA31422 B1 MA 31422B1
- Authority
- MA
- Morocco
- Prior art keywords
- microparticles
- pharmaceutical composition
- micrometers
- release pharmaceutical
- prolonged release
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Diabetes (AREA)
- Inorganic Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
L'INVENTION CONCERNE UNE COMPOSITION PHARMACEUTIQUE FAITE DE MICROPARTICULES POUR LA LIBÉRATION LENTE D'UNE SUBSTANCE ACTIVE AU MOINS PENDANT UNE PÉRIODE COUVRANT LES 6 MOIS APRÈS L'INJECTION DE LADITE COMPOSITION, LADITE COMPOSITION COMPRENANT UN GROUPE DE MICROPARTICULES FAITES D'UN COPOLYMÈRE DU TYPE PLGA QUI INCORPORENT UNE SUBSTANCE ACTIVE SOUS LA FORME D'UN SEL DE PEPTIDE INSOLUBLE DANS L'EAU; LEDIT COPOLYMÈRE COMPRENANT DE PLUS AU MOINS 75 % D'ACIDE LACTIQUE ET UNE VISCOSITÉ INHÉRENTE ENTRE 0,1 ET 0,9 DL/G, TELLE QUE MESURÉE DANS LE CHLOROFORME À 25°C ET À UNE CONCENTRATION EN POLYMÈRE DE 0,5/DL; LESDITES MICROPARTICULES AYANT DE PLUS UNE DISTRIBUTION DE DIMENSION DÉFINIE COMME SUIT : - D (V, 0,1 ) SE TROUVE ENTRE 10 ET 30 MICROMÈTRES, - D (V, 0,5) SE TROUVE ENTRE 30 ET 70 MICROMÈTRES, - D(V, 0,9) SE TROUVE ENTRE 50 ET 110 MICROMÈTRES.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP07109767 | 2007-06-06 | ||
IB2007054372 | 2007-10-27 | ||
PCT/IB2008/052241 WO2008149320A2 (fr) | 2007-06-06 | 2008-06-06 | Composition pharmaceutique à libération lente, faite de microparticules |
Publications (1)
Publication Number | Publication Date |
---|---|
MA31422B1 true MA31422B1 (fr) | 2010-06-01 |
Family
ID=40032512
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA32391A MA31422B1 (fr) | 2007-06-06 | 2009-12-01 | Composition pharmaceutique a liberation prolongee constituee de microparticules |
Country Status (32)
Country | Link |
---|---|
US (3) | US10166181B2 (fr) |
EP (3) | EP3431077A1 (fr) |
JP (1) | JP5419169B2 (fr) |
KR (1) | KR101631475B1 (fr) |
CN (1) | CN101677959B (fr) |
AP (1) | AP3000A (fr) |
AU (1) | AU2008259411B2 (fr) |
BR (1) | BRPI0812250B8 (fr) |
CA (1) | CA2688478C (fr) |
CO (1) | CO6251234A2 (fr) |
CY (2) | CY1118434T1 (fr) |
DK (2) | DK2500014T3 (fr) |
EA (1) | EA019284B1 (fr) |
ES (2) | ES2694401T3 (fr) |
HK (1) | HK1141737A1 (fr) |
HR (2) | HRP20161785T1 (fr) |
HU (2) | HUE040391T2 (fr) |
IL (1) | IL202501A (fr) |
LT (2) | LT2500014T (fr) |
MA (1) | MA31422B1 (fr) |
ME (1) | ME00959B (fr) |
MX (1) | MX2009012856A (fr) |
MY (1) | MY150450A (fr) |
NZ (1) | NZ582423A (fr) |
PL (2) | PL2164467T3 (fr) |
PT (2) | PT2500014T (fr) |
RS (2) | RS55591B1 (fr) |
SI (2) | SI2500014T1 (fr) |
TN (1) | TN2009000476A1 (fr) |
UA (1) | UA99830C2 (fr) |
WO (1) | WO2008149320A2 (fr) |
ZA (1) | ZA200907940B (fr) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
UA99830C2 (uk) | 2007-06-06 | 2012-10-10 | Дебио Ресшерчи Фармасютикю С.А. | Фармацевтична композиція з пролонгованим вивільненням, виготовлена з мікрочастинок |
PT105270B (pt) | 2010-08-26 | 2012-05-31 | Domino Ind Ceramicas S A | Camada de sílica com libertação lenta de fragrância, telha cerâmica e respectivo processo de produção |
CN105267153B (zh) * | 2015-11-27 | 2018-05-11 | 上海苏豪逸明制药有限公司 | 一种曲普瑞林缓释微粒及其制备方法 |
CN105797134B (zh) * | 2016-03-29 | 2019-06-14 | 浙江圣兆药物科技股份有限公司 | 一种难溶亮丙瑞林缓释制剂 |
EP3535297B1 (fr) | 2016-11-02 | 2022-08-10 | Debiopharm International, S.A. | Procédés d'amélioration d'une thérapie immunoconjuguée anti-cd37 |
KR102402639B1 (ko) | 2017-11-24 | 2022-05-26 | 삼성전자주식회사 | 전자 장치 및 그의 통신 방법 |
CN111000798B (zh) * | 2019-12-26 | 2021-11-23 | 四川恒博生物科技有限公司 | 一种采用原位凝胶技术的犬用非手术去势注射液 |
IT202000017191A1 (it) | 2020-07-15 | 2022-01-15 | Xbrane Biopharma Ab | Procedimento senza acqua per preparare una composizione farmaceutica per un rilascio più prolungato e controllato di triptorelina o di un suo sale |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE61935T1 (de) | 1985-02-07 | 1991-04-15 | Takeda Chemical Industries Ltd | Verfahren zur herstellung von mikrokapseln. |
US4897268A (en) * | 1987-08-03 | 1990-01-30 | Southern Research Institute | Drug delivery system and method of making the same |
GB2209937B (en) | 1987-09-21 | 1991-07-03 | Depiopharm S A | Water insoluble polypeptides |
US5225205A (en) * | 1989-07-28 | 1993-07-06 | Debiopharm S.A. | Pharmaceutical composition in the form of microparticles |
CH679207A5 (fr) * | 1989-07-28 | 1992-01-15 | Debiopharm Sa | |
MY107937A (en) | 1990-02-13 | 1996-06-29 | Takeda Chemical Industries Ltd | Prolonged release microcapsules. |
CH683149A5 (fr) * | 1991-07-22 | 1994-01-31 | Debio Rech Pharma Sa | Procédé pour la préparation de microsphères en matériau polymère biodégradable. |
FR2693905B1 (fr) * | 1992-07-27 | 1994-09-02 | Rhone Merieux | Procédé de préparation de microsphères pour la libération prolongée de l'hormone LHRH et ses analogues, microsphères et formulations obtenues. |
JP3277342B2 (ja) | 1992-09-02 | 2002-04-22 | 武田薬品工業株式会社 | 徐放性マイクロカプセルの製造法 |
ATE223702T1 (de) * | 1993-10-22 | 2002-09-15 | Genentech Inc | Verfahren und zusammensetzungen zur mikrokapselung von adjuvantien |
US5945128A (en) * | 1996-09-04 | 1999-08-31 | Romano Deghenghi | Process to manufacture implants containing bioactive peptides |
MY118835A (en) | 1997-04-18 | 2005-01-31 | Ipsen Pharma Biotech | Sustained release compositions and the process for their preparation |
US6573238B2 (en) * | 1997-11-07 | 2003-06-03 | Chiron Corporation | Method for producing sustained-release formulations |
TW200800298A (en) * | 2000-01-27 | 2008-01-01 | Zentaris Ag | Compressed microparticles for dry injection |
US20040170665A1 (en) * | 2000-06-02 | 2004-09-02 | Allergan, Inc. | Intravitreal botulinum toxin implant |
BRPI0213226B1 (pt) * | 2001-10-10 | 2016-03-01 | Pf Medicament | processo de preparação de uma composição farmacêutica sob forma de microesferas com liberação prolongada de um princípio ativo hidrossolúvel, e, microesferas |
CA2523830A1 (fr) * | 2003-04-30 | 2004-11-11 | Debiopharm S.A. | Methodes et compositions mettant en oeuvre la gonadoliberine |
KR100466637B1 (ko) * | 2003-06-26 | 2005-01-13 | 주식회사 펩트론 | 서방성 미립구의 혼합 제형을 연속한 단일 공정으로제조하는 방법 |
FR2865938B1 (fr) * | 2004-02-05 | 2006-06-02 | Sod Conseils Rech Applic | Formulation retard solide comprenant de l'acetate de triptoreline |
KR101245919B1 (ko) | 2005-12-22 | 2013-03-20 | 노파르티스 아게 | 옥트레오티드 및 2종 이상의 폴리락티드-코-글리콜리드중합체를 포함하는 서방형 제제 |
UA99830C2 (uk) | 2007-06-06 | 2012-10-10 | Дебио Ресшерчи Фармасютикю С.А. | Фармацевтична композиція з пролонгованим вивільненням, виготовлена з мікрочастинок |
-
2008
- 2008-06-06 UA UAA200913838A patent/UA99830C2/uk unknown
- 2008-06-06 EP EP18186642.7A patent/EP3431077A1/fr active Pending
- 2008-06-06 NZ NZ582423A patent/NZ582423A/en unknown
- 2008-06-06 WO PCT/IB2008/052241 patent/WO2008149320A2/fr active Application Filing
- 2008-06-06 AP AP2009005088A patent/AP3000A/xx active
- 2008-06-06 PT PT12172232T patent/PT2500014T/pt unknown
- 2008-06-06 US US12/601,649 patent/US10166181B2/en active Active
- 2008-06-06 SI SI200832014T patent/SI2500014T1/sl unknown
- 2008-06-06 KR KR1020107000176A patent/KR101631475B1/ko active IP Right Grant
- 2008-06-06 HU HUE12172232A patent/HUE040391T2/hu unknown
- 2008-06-06 LT LTEP12172232.6T patent/LT2500014T/lt unknown
- 2008-06-06 BR BRPI0812250A patent/BRPI0812250B8/pt active IP Right Grant
- 2008-06-06 EA EA200971132A patent/EA019284B1/ru unknown
- 2008-06-06 LT LTEP08763237.8T patent/LT2164467T/lt unknown
- 2008-06-06 AU AU2008259411A patent/AU2008259411B2/en active Active
- 2008-06-06 ME MEP-2009-341A patent/ME00959B/fr unknown
- 2008-06-06 EP EP08763237.8A patent/EP2164467B1/fr not_active Revoked
- 2008-06-06 PL PL08763237T patent/PL2164467T3/pl unknown
- 2008-06-06 RS RS20170032A patent/RS55591B1/sr unknown
- 2008-06-06 MY MYPI20094886 patent/MY150450A/en unknown
- 2008-06-06 CN CN200880018833.3A patent/CN101677959B/zh active Active
- 2008-06-06 MX MX2009012856A patent/MX2009012856A/es active IP Right Grant
- 2008-06-06 DK DK12172232.6T patent/DK2500014T3/en active
- 2008-06-06 RS RS20181349A patent/RS58248B1/sr unknown
- 2008-06-06 HU HUE08763237A patent/HUE031550T2/en unknown
- 2008-06-06 ES ES12172232.6T patent/ES2694401T3/es active Active
- 2008-06-06 EP EP12172232.6A patent/EP2500014B1/fr active Active
- 2008-06-06 ES ES08763237.8T patent/ES2611020T3/es active Active
- 2008-06-06 SI SI200831754A patent/SI2164467T1/sl unknown
- 2008-06-06 PT PT87632378T patent/PT2164467T/pt unknown
- 2008-06-06 JP JP2010510946A patent/JP5419169B2/ja active Active
- 2008-06-06 CA CA2688478A patent/CA2688478C/fr active Active
- 2008-06-06 PL PL12172232T patent/PL2500014T3/pl unknown
- 2008-06-06 DK DK08763237.8T patent/DK2164467T3/en active
-
2009
- 2009-11-09 TN TNP2009000476A patent/TN2009000476A1/fr unknown
- 2009-11-11 ZA ZA200907940A patent/ZA200907940B/xx unknown
- 2009-12-01 MA MA32391A patent/MA31422B1/fr unknown
- 2009-12-02 CO CO09137855A patent/CO6251234A2/es not_active Application Discontinuation
- 2009-12-03 IL IL202501A patent/IL202501A/en active IP Right Grant
-
2010
- 2010-09-02 HK HK10108338.2A patent/HK1141737A1/xx unknown
-
2016
- 2016-12-27 HR HRP20161785TT patent/HRP20161785T1/hr unknown
-
2017
- 2017-01-17 CY CY20171100060T patent/CY1118434T1/el unknown
-
2018
- 2018-11-07 HR HRP20181854TT patent/HRP20181854T1/hr unknown
- 2018-11-07 CY CY181101171T patent/CY1120891T1/el unknown
- 2018-11-15 US US16/192,674 patent/US20190192423A1/en not_active Abandoned
-
2022
- 2022-09-15 US US17/932,621 patent/US20230082575A1/en active Pending
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MA31422B1 (fr) | Composition pharmaceutique a liberation prolongee constituee de microparticules | |
Mutalik et al. | Glibenclamide transdermal patches: physicochemical, pharmacodynamic, and pharmacokinetic evaluations | |
Bhati et al. | A detailed review on oral mucosal drug delivery system | |
MA27285A1 (fr) | COMBINAISON D'AZELASTINE ET DE STEROiDES | |
TNSN98229A1 (fr) | Formulation pharmaceutique orale a liberation prolongee | |
US20240052418A1 (en) | Method for predicting a subject's response to slc modulator therapy | |
HUE028247T2 (en) | A solid oral composition comprising S1P receptor agonist and sugar alcohol | |
EA200900270A1 (ru) | Системы регулируемого высвобождения и способ их приготовления | |
MA26859A1 (fr) | Forme posologique de medicament commandée par un hydrogel. | |
ATE429416T1 (de) | Cyanophenoxy-carbonsäuren und zusammensetzungen für die freisetzung aktiver substanzen | |
DE60121857D1 (de) | Arzneimittelzusammensetzung mit verzögerter Wirkstoffabgabe | |
CY1107711T1 (el) | Υπογλωσσια χορηγηση φαρμακευτικης συνθεσης ως αγωγη εναντι οξεων διαταραχων | |
DK1663216T3 (da) | Tacrolimus-holdige sammensætninger med modificeret frigivelse | |
BRPI9711856B8 (pt) | métodos para preparação de um agente ativo, substancialmente insolúvel em água e composição para liberação in vivo de um agente ativo | |
CA2372576A1 (fr) | Composition pharmaceutique de fenofibrate presentant une biodisponibilite elevee et son procede de preparation | |
BRPI0113477B8 (pt) | proteína de fusão para distribuição de um peptídeo, proteína, glicoproteína ou oligonucleotídeo em uma célula | |
WO2001082895A3 (fr) | Formulation et comprimes de liberation soutenue de guaifenesine | |
MA30598B1 (fr) | Composition pharmaceutique contenant un acide tetrahydrofolique. | |
BRPI0317682B1 (pt) | Composição farmacêutica de liberação modificada na forma de uma cápsula | |
TNSN08152A1 (fr) | Composition a liberation prolongee de l'actif, son procede de preparation et son utilisation | |
MA31006B1 (fr) | Composition a liberation prolongee et procede de production correspondant | |
WO2018018010A1 (fr) | Mutants de fgf et leurs utilisations | |
DE60042972D1 (de) | Trimetazidine enthaltendes Arzneimittel mit verzögerter Wirkstoffabgabe und Verfahren zur Herstellung | |
WO2004006854A3 (fr) | Procede d'identification d'agents biologiquement actifs | |
Nepal et al. | Intracellular distribution and transcriptional regulation of Atlantic salmon (Salmo salar) Rab5c, 7a and 27a homologs by immune stimuli |