MA24261A1 - Pyridines bicycliques condensees. - Google Patents

Pyridines bicycliques condensees.

Info

Publication number
MA24261A1
MA24261A1 MA24705A MA24705A MA24261A1 MA 24261 A1 MA24261 A1 MA 24261A1 MA 24705 A MA24705 A MA 24705A MA 24705 A MA24705 A MA 24705A MA 24261 A1 MA24261 A1 MA 24261A1
Authority
MA
Morocco
Prior art keywords
condensed bicyclic
pyridines
bicyclic pyridines
condensed
bicyclic
Prior art date
Application number
MA24705A
Other languages
English (en)
Inventor
Brandes Arndt
Schmidt Gunter
Angerbauer Rolf
Dieter Bremm Klaus
Schmidt Delf
Schhmacher Joachim
Ligers Michael
Schmeck Carsten
Bischoff Hilmar
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of MA24261A1 publication Critical patent/MA24261A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/06—Ring systems of three rings
    • C07D221/16—Ring systems of three rings containing carbocyclic rings other than six-membered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
MA24705A 1996-07-08 1997-07-07 Pyridines bicycliques condensees. MA24261A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19627430A DE19627430A1 (de) 1996-07-08 1996-07-08 Bicyclisch kondensierte Pyridine

Publications (1)

Publication Number Publication Date
MA24261A1 true MA24261A1 (fr) 1998-04-01

Family

ID=7799218

Family Applications (1)

Application Number Title Priority Date Filing Date
MA24705A MA24261A1 (fr) 1996-07-08 1997-07-07 Pyridines bicycliques condensees.

Country Status (30)

Country Link
US (1) US6063788A (fr)
EP (1) EP0825185A1 (fr)
JP (1) JPH1067751A (fr)
KR (1) KR980009247A (fr)
CN (1) CN1172803A (fr)
AR (1) AR007716A1 (fr)
AU (1) AU722365B2 (fr)
BG (1) BG61972B1 (fr)
BR (1) BR9703886A (fr)
CA (1) CA2209609A1 (fr)
CO (1) CO4870759A1 (fr)
CZ (1) CZ214797A3 (fr)
DE (1) DE19627430A1 (fr)
EE (1) EE9700151A (fr)
HN (1) HN1997000082A (fr)
HR (1) HRP970331A2 (fr)
HU (1) HUP9701158A1 (fr)
ID (1) ID17659A (fr)
IL (1) IL121235A0 (fr)
MA (1) MA24261A1 (fr)
NO (1) NO308738B1 (fr)
NZ (1) NZ328260A (fr)
PE (1) PE87798A1 (fr)
PL (1) PL320954A1 (fr)
SG (1) SG46782A1 (fr)
SK (1) SK92697A3 (fr)
TN (1) TNSN97116A1 (fr)
TR (1) TR199700583A2 (fr)
YU (1) YU28897A (fr)
ZA (1) ZA976021B (fr)

Families Citing this family (35)

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US6262277B1 (en) 1994-09-13 2001-07-17 G.D. Searle And Company Intermediates and processes for the preparation of benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake
US6268392B1 (en) 1994-09-13 2001-07-31 G. D. Searle & Co. Combination therapy employing ileal bile acid transport inhibiting benzothiepines and HMG Co-A reductase inhibitors
US6642268B2 (en) 1994-09-13 2003-11-04 G.D. Searle & Co. Combination therapy employing ileal bile acid transport inhibiting benzothipines and HMG Co-A reductase inhibitors
MXPA01006469A (es) 1998-12-23 2004-03-10 Searle & Co Combinaciones de inhibidores de proteina de transferencia de ester colesterilico y derivados de acido fibrico para indicaciones cardiovasculares.
JP2002533408A (ja) 1998-12-23 2002-10-08 ジー．ディー．サール エルエルシー 心臓血管に適用するためのコレステリルエステル転送タンパク質阻害剤およびニコチン酸誘導体の組み合わせ
DK1140185T3 (da) 1998-12-23 2003-09-29 Searle Llc Kombinationer af cholesterylestertransferhæmmere og galdesyre kompleksdannende forbindelser til hjertekar indikationer
DE69907960T2 (de) 1998-12-23 2004-02-26 G.D. Searle Llc, Chicago Kombinationen von ileumgallensäuretransports inhibitoren und fibronsäure derivaten für kardiovaskuläre indikationen
ES2200587T3 (es) 1998-12-23 2004-03-01 G.D. Searle Llc Combinaciones de inhibidors del transporte de acidos biliares del ileon e inhibidores de la proteina de transferencia de colesteril ester para indicaciones cardiovasculares.
DK1140190T3 (da) 1998-12-23 2002-12-23 Searle Llc Kombinationer af ileumgaldesyretransport-inhibitorer og galdesyre-sekvestreringsmidler til cardiovaskulære indikatorer
AU2157400A (en) 1998-12-23 2000-07-31 G.D. Searle & Co. Combinations of cholesteryl ester transfer protein inhibitors and hmg coa reductase inhibitors for cardiovascular indications
US6544974B2 (en) 1999-09-23 2003-04-08 G.D. Searle & Co. (R)-chiral halogenated substituted fused heterocyclic amino compounds useful for inhibiting cholesteryl ester transfer protein activity
US6924313B1 (en) 1999-09-23 2005-08-02 Pfizer Inc. Substituted tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity
US20010018446A1 (en) 1999-09-23 2001-08-30 G.D. Searle & Co. Substituted N-Aliphatic-N-Aromatictertiary-Heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity
AU2001240115A1 (en) 2000-03-10 2001-09-24 Pharmacia Corporation Method for the preparation of tetrahydrobenzothiepines
US20040219619A1 (en) * 2000-07-21 2004-11-04 Ester Fernandez-Salas Methods of identifying compounds that alter toxin persistence and/or protease activity
US6958328B2 (en) * 2001-04-18 2005-10-25 Ortho-Mcneil Pharmaceutical, Inc Arylindenopyridines and related therapeutic and prophylactic methods
US6903109B2 (en) 2001-04-18 2005-06-07 Ortho-Muniel Pharmaceutical, Inc. Arylindenopyridines and related therapeutic and prophylactic methods
US20050239782A1 (en) * 2001-04-18 2005-10-27 Heintzelman Geoffrey R Arylindenopyridines and related therapeutic and prophylactic methods
MXPA03011784A (es) 2001-06-22 2004-04-02 Pfizer Prod Inc Composiciones farmaceuticas de dispersiones de farmacos y polimeros neutros.
CA2448825C (fr) 2001-06-22 2009-08-11 Pfizer Products Inc. Compositions pharmaceutiques de produits d'adsorption de medicament amorphe
MXPA04003524A (es) 2001-11-02 2004-07-23 Searle Llc Compuestos de benzotiepina monofluorados y difluorados novedosos como inhibidores de transporte de acido biliar co-dependiente de sodio apical (asbt) y captacion de taurocolato.
CA2471639A1 (fr) 2002-01-17 2003-07-31 Pharmacia Corporation Nouveaux composes d'alkyl/aryl hydroxy ou cetothiepine servant d'inhibiteurs du transport des acides biliaires de type ileal et de l'absorption de taurocholate
EP1469832B2 (fr) 2002-02-01 2016-10-26 Bend Research, Inc. Compositions pharmaceutiques de dispersions amorphes de medicaments et materiaux formant des microphases lipophiles
US20040127510A1 (en) * 2002-04-16 2004-07-01 Heintzelman Geoffrey R. Arylindenopyridines and arylindenopyrimidines and related therapeutic and prophylactic methods
CL2004001884A1 (es) 2003-08-04 2005-06-03 Pfizer Prod Inc Procedimiento de secado por pulverizacion para la formacion de dispersiones solidas amorfas de un farmaco y polimeros.
MXPA06001417A (es) 2003-08-04 2006-05-15 Pfizer Prod Inc Composiciones farmaceuticas de adsorbatos de farmacos amorfos y materiales que forman microfases lipofilas.
CN101342162A (zh) 2003-09-26 2009-01-14 日本烟草产业株式会社 抑制残余脂蛋白产生的方法
ES2332051T3 (es) 2003-10-08 2010-01-25 Eli Lilly And Company Compuestos y procedimientos para tratar dislipidemia.
US20070208003A1 (en) 2004-03-26 2007-09-06 Bell Michael G Compounds and methods for treating dyslipidemia
MX2007007188A (es) * 2004-12-18 2007-08-14 Bayer Healthcare Ag Derivados de tetrahidroquinolina sustituidos en 4 con cicloalquilo y su uso como medicamentos.
EP1844078B1 (fr) 2005-02-03 2016-09-28 Bend Research, Inc Compositions pharmaceutiques a efficacite amelioree
AU2006304836A1 (en) 2005-10-21 2007-04-26 Novartis Ag Combination of a renin-inhibitor and an anti-dyslipidemic agent and/or an antiobesity agent
DE102006012548A1 (de) * 2006-03-18 2007-09-20 Bayer Healthcare Ag Substituierte Chromanol-Derivate und ihre Verwendung
PA8801401A1 (es) * 2007-10-25 2009-05-15 Janssen Pharmaceutica Nv Arilindenopirimidinas y su uso como adenosina a2a
WO2012027331A1 (fr) 2010-08-27 2012-03-01 Ironwood Pharmaceuticals, Inc. Compositions et procédés pour traiter ou prévenir un syndrome métabolique et des maladies et troubles associés

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5169857A (en) * 1988-01-20 1992-12-08 Bayer Aktiengesellschaft 7-(polysubstituted pyridyl)-hept-6-endates useful for treating hyperproteinaemia, lipoproteinaemia or arteriosclerosis
GB8626344D0 (en) * 1986-11-04 1986-12-03 Zyma Sa Bicyclic compounds
NO177005C (no) * 1988-01-20 1995-07-05 Bayer Ag Analogifremgangsmåte for fremstilling av substituerte pyridiner, samt mellomprodukter til bruk ved fremstillingen
IE892088L (en) * 1988-07-12 1990-01-12 William Henry Deryk Morris Quinoline derivatives, their production and use
NZ237097A (en) * 1990-02-26 1993-12-23 Squibb & Sons Inc Pyridine derivatives substituted in the 3-position by a phosphinic moiety.
JPH059179A (ja) * 1990-09-27 1993-01-19 Takeda Chem Ind Ltd 複素環化合物、その製造法及びａｃａｔ阻害剤

Also Published As

Publication number Publication date
NO973144L (no) 1998-01-09
EP0825185A1 (fr) 1998-02-25
AU2844897A (en) 1998-01-15
AR007716A1 (es) 1999-11-10
TR199700583A2 (xx) 1998-01-21
PL320954A1 (en) 1998-01-19
HU9701158D0 (en) 1997-09-29
ZA976021B (en) 1998-02-02
SG46782A1 (en) 1998-02-20
JPH1067751A (ja) 1998-03-10
IL121235A0 (en) 1998-01-04
HN1997000082A (es) 1997-12-26
NZ328260A (en) 1998-09-24
CZ214797A3 (cs) 1998-01-14
EE9700151A (et) 1998-02-16
BG101746A (en) 1998-03-31
HRP970331A2 (en) 1998-08-31
BG61972B1 (bg) 1998-11-30
CN1172803A (zh) 1998-02-11
ID17659A (id) 1998-01-15
NO973144D0 (no) 1997-07-07
TNSN97116A1 (fr) 2005-03-15
SK92697A3 (en) 1998-02-04
HUP9701158A1 (hu) 1999-09-28
CA2209609A1 (fr) 1998-01-08
BR9703886A (pt) 1998-11-03
DE19627430A1 (de) 1998-01-15
CO4870759A1 (es) 1999-12-27
KR980009247A (ko) 1998-04-30
NO308738B1 (no) 2000-10-23
US6063788A (en) 2000-05-16
PE87798A1 (es) 1999-02-13
AU722365B2 (en) 2000-08-03
YU28897A (sh) 2000-03-21

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