LV12469B - Disks analīžu veikšanai - Google Patents
Disks analīžu veikšanai Download PDFInfo
- Publication number
- LV12469B LV12469B LVP-99-137A LV990137A LV12469B LV 12469 B LV12469 B LV 12469B LV 990137 A LV990137 A LV 990137A LV 12469 B LV12469 B LV 12469B
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
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- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502738—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
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- B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
- G01N35/00069—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides whereby the sample substrate is of the bio-disk type, i.e. having the format of an optical disk
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- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
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- B01L2200/0605—Metering of fluids
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- B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
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- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
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- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
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- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
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- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Clinical Laboratory Science (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Dispersion Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
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- General Physics & Mathematics (AREA)
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- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Sampling And Sample Adjustment (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Steroid Compounds (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Claims (19)
- LV 12469 IZGUDROJUMA FORMULA 1. Optisks disks, kas piemērots lasīšanai ar lāzera lasītāju, ietver pirmo sektoru ar būtībā neatkarīgām analīzes ierīcēm paraugā iespējamā analīta saistīšanai vai reaģēšanai vismaz vienā, iepriekšnoteiktā atrašanās vietā pirmajā sektorā, un pēc izvēles otru sektoru, kas ietver analīzes vadīšanas kontrolierīces un analīta atrašanās vietas datus attiecībā uz paraugā iespējamajiem vienu vai vairākiem analītiem, pieejamus lasītājam, un kur analīta klātbūtne vai iztrūkšana minētajā atrašanās vietā ir nosakāma ar lasītāju, izmantojot kontrolierīces un atrašanās vietas datus un parauga ieejas portu.
- 2. Optisks disks saskaņā ar 1. punktu, kur parauga ieejas ports atrodas šķidruma saskares vietā ar analīzes ierīcēm.
- 3. Aparāts analīzes vadīšanai, kas ietver optisku disku, lāzera lasītāju un informācijas procesoru, kur disks ietver parauga ieejas portu, pirmo sektoru ar būtībā neatkarīgām analīzes ierīcēm paraugā iespējamā analīta saistīšanai vai reaģēšanai vismaz vienā, iepriekšnoteiktā atrašanās vietā pirmajā sektorā, un pēc izvēles otru sektoru, kas ietver kontroldatus analīzes vadīšanai un analīta atrašanās vietas datus attiecībā uz paraugā iespējamiem vienu vai vairākiem analītiem, pieejamiem lasītājam un apstrādājamiem ar informācijas procesoru, kur disks ir piemērots lasīšanai ar lasītāju un informācijas procesors ir piemērots analīta klātbūtnes vai iztrūkšanas noteikšanai minētajā atrašanās vietā, izmantojot kontroles datus un atrašanās vietas datus.
- 4. Aparāts saskaņā ar 3. punktu, kur lasītājs ir piemērots saslēgšanai ar informācijas procesoru.
- 5. Aparāts saskaņā ar 5. punktu, kur informācijas procesors ir personālais dators.
- 6. Disks saskaņā ar 1. punktu, kur analīzes ierīces ietver šķidruma uzglabāšanas ierīces un šķidruma pārvades ierīces, kas izveidotas diska virsmā.
- 7. Disks saskaņā ar 6. punktu, kur šķidruma pārvades ierīces ietver kapilāru cauruli.
- 8. Disks saskaņā ar 7. punktu, kur šķidruma pārvades ierīces satur vārstu.
- 9. Disks saskaņā ar 6. punktu, kur disks satur elektroķīmiskas enerģijas ierīces.
- 10. Disks saskaņā ar 1. punktu, kur analīzes ierīces satur parauga portu, parauga sagatavošanas sektoru, analīta izdalīšanas sektoru un analīzes sektoru, kur analīts ir lokalizēts.
- 11. Disks saskaņā ar 6. punktu, kur šķidruma pārvades ierīces ir jūtīgas attiecībā uz centrbēdzes spēkiem vai elektrisku lauku.
- 12. Disks saskaņā ar 1. punktu, kur disks ietver daudzus pirmos sektorus, kas piemēroti liela skaita analītu analizēšanai. 2
- 13. Disks saskaņā ar 1. punktu, kas tālāk satur daudzus pirmos sektorus, kas piemēroti tāda paša analīta vai atšķirīgu analītu analīzei, kur katrs no minētajiem daudzajiem sektoriem ir piemērots šķidrumžhsaskarei ar parauga portu.
- 14. Analīzes elements, kas satur substrātu, pie substrāta saistītu pirmo oligonukleotīdu, telpisku molekulu, kas piesaistīta pirmā oligonukleotīda pirmajam galam ar otru nukleotīdu, kas ir papildinājums pirmajam oligonukleotīdam, kur telpiskā molekula bez tam satur ierīces piesaistīšanai analītam paraugā, un otru galu, kas ir detektējams ar detektēšanas ierīcēm, bez tam telpiskā molekula starp pirmo un otro galu satur vietu, kas ir atšķeļama, saistīšanas ierīcēm ir pirmā daļa starp telpiskās molekulas pirmo galu un atšķeļamo vietu piesaistīšanai pie analīta pirmās daļas un otra daļa starp telpiskās molekulas otro galu un atšķeļamo vietu piesaistīšanai pie analīta otras daļas, kur atšķeļamo vietu var atšķelt bez ķīmiskas iedarbības uz analīta saistīšanas zonu.
- 15. Analīzes komponents, kas piemērots lasīšanai ar CD-ROM vai DVD lasītāju, ietver optisku disku ar parauga ieejas portu un būtībā neatkarīgas analīzes ierīces diskā, lai paraugā iespējamo analītu piesaistītu vismaz vienai, iepriekšnoteiktai atrašanās vietai uz diska, un ierīces minētajā atrašanās vietā analīta klātbūtnes vai iztrūkšanas iespējamajai detektēšanai ar CD-Rom vai DVD lasītāju.
- 16. Optisks disks, kas piemērots lasīšanai ar CD-ROM vai DVD lasītāju, ietver parauga ieejas portu, būtībā neatkarīgas analīzes ierīces paraugā iespējamā analīta lokalizēšanai vismaz vienā, iepriekšnoteiktā atrašanās vietā uz diska un ierīces minētajā atrašanās vietā analīta klātbūtnes vai iztrūkšanas detektēšanai ar CD-Rom vai DVD lasītāju.
- 17. Optiskais disks saskaņā ar 3. punktu, kur lāzerlasītājs ir CD-ROM vai DVD diska lasītājs.
- 18. Aparāts saskaņā ar 3. punktu, kur lāzerlasītājs ir CD-ROM vai DVD diska lasītājs.
- 19. Analīzes elements, kas satur substrātu, pirmo oligonukleotīda saiti pie substrāta, telpiskas molekulas saiti pirmā oligonukleotīda pirmajā galā ar otru nukleotīdu, kas ir papildinājums pirmajam oligonukleotīdam, kur telpiskā molekula bez tam satur ierīces piesaistīšanai pie analīta paraugā, un otru galu, kas ir detektējams ar detektēšanas ierīcēm, bez tam telpiskā molekula starp pirmo un otro galu satur vietu, kas ir atšķeļama, saistīšanas ierīcēm ir pirmā daļa starp telpiskās molekulas pirmo galu un atšķeļamo vietu piesaistīšanai pie analīta pirmās daļas un otra daļa starp telpiskās molekulas otro galu un atšķeļamo vietu piesaistīšanai pie analīta otras daļas, kur atšķeļamo vietu var atšķelt neatkarīgi no analīta.
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PCT/US1998/004377 WO1998038510A2 (en) | 1997-02-28 | 1998-02-27 | Laboratory in a disk |
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- 1998-02-27 KR KR1019997007888A patent/KR20000075815A/ko not_active Application Discontinuation
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- 1998-02-27 SK SK1180-99A patent/SK118099A3/sk unknown
- 1998-02-27 CN CN98802949A patent/CN1249816A/zh active Pending
- 1998-02-27 RO RO99-00932A patent/RO119751B1/ro unknown
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- 1998-02-27 WO PCT/US1998/004377 patent/WO1998038510A2/en not_active Application Discontinuation
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- 1998-04-21 US US09/064,636 patent/US6030581A/en not_active Expired - Fee Related
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