LV10620B - Method for preparation of 10-deacethylbaccatine - Google Patents

Method for preparation of 10-deacethylbaccatine

Info

Publication number
LV10620B
LV10620B LVP-93-1119A LV931119A LV10620B LV 10620 B LV10620 B LV 10620B LV 931119 A LV931119 A LV 931119A LV 10620 B LV10620 B LV 10620B
Authority
LV
Latvia
Prior art keywords
deacethylbaccatine
yew
preparation
deacetylbaccatin iii
taxus
Prior art date
Application number
LVP-93-1119A
Other languages
English (en)
Other versions
LV10620A (lv
Inventor
Margraff Rodolphe
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of LV10620A publication Critical patent/LV10620A/xx
Publication of LV10620B publication Critical patent/LV10620B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epoxy Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Extraction Or Liquid Replacement (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
LVP-93-1119A 1992-10-05 1993-10-04 Method for preparation of 10-deacethylbaccatine LV10620B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9211745A FR2696462B1 (fr) 1992-10-05 1992-10-05 Procédé d'obtention de la désacétyl-10 baccatine III.

Publications (2)

Publication Number Publication Date
LV10620A LV10620A (lv) 1995-04-20
LV10620B true LV10620B (en) 1995-10-20

Family

ID=9434123

Family Applications (1)

Application Number Title Priority Date Filing Date
LVP-93-1119A LV10620B (en) 1992-10-05 1993-10-04 Method for preparation of 10-deacethylbaccatine

Country Status (30)

Country Link
US (2) US5393896A (de)
EP (1) EP0663909B1 (de)
JP (1) JP3299753B2 (de)
KR (1) KR100301238B1 (de)
CN (1) CN1041310C (de)
AT (1) ATE147381T1 (de)
AU (1) AU680440B2 (de)
CA (2) CA2146248C (de)
CZ (2) CZ286452B6 (de)
DE (1) DE69307333T2 (de)
DK (1) DK0663909T3 (de)
EE (1) EE03124B1 (de)
ES (1) ES2095672T3 (de)
FI (1) FI109797B (de)
FR (1) FR2696462B1 (de)
GE (1) GEP19981433B (de)
GR (1) GR3022229T3 (de)
HU (1) HU225969B1 (de)
LT (1) LT3465B (de)
LV (1) LV10620B (de)
MX (1) MX9305770A (de)
NO (1) NO310414B1 (de)
NZ (1) NZ256449A (de)
PL (1) PL173993B1 (de)
RU (1) RU2108330C1 (de)
SK (1) SK280335B6 (de)
TW (1) TW404944B (de)
UA (1) UA40601C2 (de)
WO (1) WO1994007881A1 (de)
ZA (1) ZA937312B (de)

Families Citing this family (80)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101222904B1 (ko) 1993-07-19 2013-01-17 안지오테크 파마슈티칼즈, 인코포레이티드 항맥관형성 조성물, 당해 조성물로 피복된 스텐트 및 당해 스텐트의 제조방법
FR2714053B1 (fr) * 1993-12-22 1996-03-08 Pf Medicament Procédé d'extraction et d'isolement de la 10-désacétylbaccatine III.
CN1112433A (zh) * 1994-05-24 1995-11-29 郭明 红豆杉属植物提取物及其应用
AU716005B2 (en) 1995-06-07 2000-02-17 Cook Medical Technologies Llc Implantable medical device
FR2736355B1 (fr) * 1995-07-07 1997-11-07 Pf Medicament Procede d'extraction et d'isolement de la 10-desacetylbaccatine iii
US5965752A (en) * 1996-08-23 1999-10-12 Institut National De La Recherche Scientifique Preparative scale isolation and purification of taxanes
WO1999008986A1 (en) * 1997-08-21 1999-02-25 Florida State University Method for the synthesis of taxanes
US6066748A (en) * 1997-12-17 2000-05-23 Han; Man Woo Process of extracting TAXOL® from taxus cuspidata
DE69901819T2 (de) * 1998-01-14 2003-01-30 Bristol-Myers Squibb Co., Princeton Neue kristallkomplexe von baccatin iii mit imidazol, 2-methylimidazol or isopropanol
US20040234472A1 (en) 2001-04-20 2004-11-25 Jackson John K. Micellar drug delivery systems for hydrophobic drugs
US6136989A (en) * 1998-12-30 2000-10-24 Phytogen Life Sciences, Incorporated Method for high yield and large scale extraction of paclitaxel from paclitaxel-containing material
US5969165A (en) * 1999-01-07 1999-10-19 508037 (Nb) Inc. Isolation and purification of paclitaxel and other related taxanes by industrial preparative low pressure chromatography on a polymeric resin column
US6495705B2 (en) 2000-03-16 2002-12-17 Napro Biotherapeutics, Inc. Efficient process for the production of 10-DAB III by selective hydrazinolysis of various taxanes
US6281368B1 (en) 2000-03-16 2001-08-28 Napro Biotherapeutics, Inc. Simple and efficient hydrazinolysis of C-10 and C-13 ester functionalities of taxanes to obtain 10-DAB III
CA2307393A1 (en) 2000-05-01 2001-11-01 The University Of British Columbia Ginsenoside chemotherapy
US20030157170A1 (en) * 2001-03-13 2003-08-21 Richard Liggins Micellar drug delivery vehicles and precursors thereto and uses thereof
US20030054036A1 (en) * 2001-03-13 2003-03-20 Richard Liggins Micellar drug delivery vehicles and precursors thereto and uses thereof
US7351542B2 (en) 2002-05-20 2008-04-01 The Regents Of The University Of California Methods of modulating tubulin deacetylase activity
ATE457716T1 (de) 2002-12-30 2010-03-15 Angiotech Int Ag Wirkstofffreisetzung von schnell gelierender polymerzusammensetzung
CA2512170A1 (en) * 2002-12-31 2004-07-22 Natural Pharmaceuticals Inc. Pelletizing yew biomass for extraction of taxanes and other natural products
US20070172446A1 (en) 2003-05-16 2007-07-26 Intermune, Inc. Synthetic chemokine receptor ligands and methods of use thereof
WO2005037329A2 (en) * 2003-10-17 2005-04-28 Tyco Healthcare Group, Lp Surgical stapling device with independent tip rotation
US20060127510A1 (en) * 2003-12-30 2006-06-15 Natural Pharmaceuticals, Inc. Harvesting and pelletizing yew biomass for extraction of taxanes and other natural products
US8003122B2 (en) 2004-03-31 2011-08-23 Cordis Corporation Device for local and/or regional delivery employing liquid formulations of therapeutic agents
US7846940B2 (en) 2004-03-31 2010-12-07 Cordis Corporation Solution formulations of sirolimus and its analogs for CAD treatment
US7989490B2 (en) 2004-06-02 2011-08-02 Cordis Corporation Injectable formulations of taxanes for cad treatment
US20050240036A1 (en) * 2004-04-23 2005-10-27 Phytogen Life Sciences Inc. Semi-synthesis of taxane intermediates from a mixture of taxanes
US20050250954A1 (en) * 2004-05-04 2005-11-10 Phytogen Life Sciences Inc. Semi-synthesis and isolation of taxane intermediates from a mixture of taxanes
US20050272807A1 (en) * 2004-06-04 2005-12-08 Phytogen Life Sciences Inc. Semi-synthesis of taxane intermediates and their conversion to paclitaxel and docetaxel
WO2006014345A1 (en) * 2004-07-02 2006-02-09 Ivax Pharmaceuticals S.R.O. Process for the separation of paclitaxel and cephalomannin
US7597884B2 (en) 2004-08-09 2009-10-06 Alios Biopharma, Inc. Hyperglycosylated polypeptide variants and methods of use
US20060188508A1 (en) 2005-02-17 2006-08-24 Cohen Stanley N Methods and compositions for modulating angiogenesis
WO2007045093A1 (en) * 2005-10-21 2007-04-26 Her Majesty The Queen In Right Of Canada As Represented By The Minister Of Natural Resources Canada, Canadian Forest Service Preparation of taxanes
CA2922029C (en) 2006-03-22 2017-11-28 Medigene Ag A combination of a cationic liposomal preparation comprising an antimitotic agent and a non-liposomal preparation comprising an antimitotic agent
EP2380606B1 (de) 2006-06-30 2018-03-21 Cook Medical Technologies LLC Verfahren zur Herstellung und Modifizierung von Taxanbeschichtungen für implantierbare medizinische Vorrichtungen
CN100404520C (zh) * 2006-08-15 2008-07-23 北京诺瑞医药技术有限公司 从欧洲红豆杉枝叶中提取分离10－去乙酰基巴卡汀ⅲ的方法
CN101230053B (zh) * 2007-12-04 2010-06-02 北京诺瑞医药技术有限公司 从红豆杉枝叶中超声提取分离10-去乙酰基巴卡汀ⅲ的方法
US8420110B2 (en) 2008-03-31 2013-04-16 Cordis Corporation Drug coated expandable devices
US8409601B2 (en) 2008-03-31 2013-04-02 Cordis Corporation Rapamycin coated expandable devices
US8273404B2 (en) 2008-05-19 2012-09-25 Cordis Corporation Extraction of solvents from drug containing polymer reservoirs
EP2859916B1 (de) 2008-05-22 2017-11-29 Galera Labs, LLC Antimitotika mit Superoxid Dismutase Mimetika für die Kombinationstherapie gegen Krebs
EP2310507A4 (de) 2008-07-08 2013-03-20 David Gladstone Inst Verfahren und zusammensetzungen zur angiogenesemodulierung
US8642063B2 (en) 2008-08-22 2014-02-04 Cook Medical Technologies Llc Implantable medical device coatings with biodegradable elastomer and releasable taxane agent
US20120303115A1 (en) 2011-05-25 2012-11-29 Dadino Ronald C Expandable devices coated with a rapamycin composition
US20120302954A1 (en) 2011-05-25 2012-11-29 Zhao Jonathon Z Expandable devices coated with a paclitaxel composition
EP2760848B1 (de) 2011-09-26 2018-11-28 Fresenius Kabi Oncology Limited Verfahren zur herstellung von cabazitaxel mit c(7) -oh und c(13) -oh-silylierung oder einfach c(7) -oh-silylierung
US9956385B2 (en) 2012-06-28 2018-05-01 The Spectranetics Corporation Post-processing of a medical device to control morphology and mechanical properties
EP3539563A1 (de) 2012-07-19 2019-09-18 Redwood Bioscience, Inc. Für cd22 spezifischer antikörper und verfahren zur verwendung davon
WO2014074218A1 (en) 2012-11-12 2014-05-15 Redwood Bioscience, Inc. Compounds and methods for producing a conjugate
EP3881868B1 (de) 2013-02-15 2023-09-27 The Regents Of The University Of California Chimärer antigen-rezeptor und verfahren zur verwendung davon
EP2970124B1 (de) 2013-03-14 2019-05-22 The Board of Trustees of the Leland Stanford Junior University Mitochondriale aldehyd-dehydrogenase-2-modulatoren und verfahren zur verwendung davon
CN103508984B (zh) * 2013-10-22 2017-03-08 北京诺瑞医药技术有限公司 连续浸漉吸附富集法从红豆杉中提取10-dab的方法
JP6745218B2 (ja) 2013-11-27 2020-08-26 レッドウッド バイオサイエンス， インコーポレイテッド ヒドラジニル−ピロロ化合物及び複合体を生成するための方法
JP6615769B2 (ja) 2014-02-19 2019-12-04 アルデア ファーマシューティカルズ インコーポレイテッド ミトコンドリアアルデヒドデヒドロゲナーゼ２（ａｌｄｈ２）に結合する多環式アミド
AU2016326747A1 (en) 2015-09-25 2018-03-01 Zy Therapeutics Inc. Drug formulation based on particulates comprising polysaccharide-vitamin conjugate
EP3373977A4 (de) 2015-11-12 2019-07-17 The Board of Trustees of the Leland Stanford Junior University Zellenpenetrierende, guanidiniumreiche oligophosphotriester zur wirkstoff- und sondenfreisetzung
HUP1500603A2 (en) * 2015-12-11 2017-06-28 Rotachrom Tech Kft Process for the separation of 10-deacetyl baccatin iii
TWI760319B (zh) 2015-12-30 2022-04-11 杏國新藥股份有限公司 乳癌治療
US11208632B2 (en) 2016-04-26 2021-12-28 R.P. Scherer Technologies, Llc Antibody conjugates and methods of making and using the same
EP4019007A1 (de) 2016-06-01 2022-06-29 Servier IP UK Limited Formulierungen von polyalkylen-oxid-asparaginase und verfahren zur herstellung und verwendung davon
CN106397371A (zh) * 2016-08-31 2017-02-15 重庆市碚圣医药科技股份有限公司 一种用曼地亚红豆杉高产10‑dabⅲ的方法
CN110267650A (zh) 2017-01-05 2019-09-20 杏国新药股份有限公司 胰脏癌治疗
MX2019008503A (es) 2017-01-18 2019-09-13 F1 Oncology Inc Receptores de antigenos quimericos contra axl o ror2 y metodos de uso de los mismos.
EP3388082A1 (de) 2017-04-13 2018-10-17 Galera Labs, LLC Kombinationskrebsimmuntherapie mit makrocyclischem pentaaza-ringkomplex
WO2019152661A1 (en) 2018-01-31 2019-08-08 Galera Labs, Llc Combination cancer therapy with pentaaza macrocyclic ring complex and platinum-based anticancer agent
KR20210009315A (ko) 2018-04-11 2021-01-26 오하이오 스테이트 이노베이션 파운데이션 안약 전달용 서방형 마이크로 입자를 이용한 방법 및 조성물
WO2020018700A1 (en) 2018-07-18 2020-01-23 Manzanita Pharmaceuticals, Inc. Conjugates for delivering an anti-cancer agent to nerve cells, methods of use and methods of making thereof
TW202038994A (zh) 2019-01-14 2020-11-01 美商醫格耐免疫治療公司 重組痘瘡病毒及其使用方法
JP2022520220A (ja) 2019-02-14 2022-03-29 イグナイト イミュノセラピー インク 組換えワクシニアウイルスおよびその使用方法
CN113692413A (zh) 2019-04-02 2021-11-23 肯乔克蒂生物技术股份有限公司 外排泵-癌症抗原多特异性抗体以及与其相关的组合物、试剂、试剂盒和方法
EP4073088A1 (de) 2019-12-12 2022-10-19 Ignite Immunotherapy, Inc. Variantes onkolytisches vaccinia-virus und verwendungsverfahren dafür
EP4097134A1 (de) 2020-01-29 2022-12-07 Kenjockety Biotechnology, Inc. Anti-mdr1-antikörper und verwendungen davon
EP4161564A1 (de) 2020-06-04 2023-04-12 Kenjockety Biotechnology, Inc. Multispezifische antikörper gegen abcg2-effluxpumpen-krebsantigen und zusammensetzungen, reagenzien, kits und verfahren im zusammenhang damit
CA3182472A1 (en) 2020-06-04 2021-12-09 Kenjockety Biotechnology, Inc. Anti-abcg2 antibodies and uses thereof
CN116133671A (zh) 2020-07-14 2023-05-16 辉瑞公司 重组牛痘病毒
CA3193588A1 (en) 2020-09-02 2022-03-10 Kenjockety Biotechnology, Inc. Anti-abcc1 antibodies and uses thereof
US20240010747A1 (en) 2020-11-13 2024-01-11 Kenjockety Biotechnology, Inc. Anti-mrp4 (encoded by abcc4 gene) antibodies and uses thereof
CN112694458A (zh) * 2020-12-29 2021-04-23 重庆臻源红豆杉发展有限公司 一种10-去乙酰基巴卡亭ⅲ提取纯化方法
KR20240116829A (ko) 2021-12-13 2024-07-30 윌리엄 로버트 아라툰 리빙 트러스트 데이티드 어거스트 29, 2016 항-abcb1 항체
WO2023159220A1 (en) 2022-02-18 2023-08-24 Kenjockety Biotechnology, Inc. Anti-cd47 antibodies

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2601675B1 (fr) * 1986-07-17 1988-09-23 Rhone Poulenc Sante Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2601676B1 (fr) 1986-07-17 1988-09-23 Rhone Poulenc Sante Procede de preparation du taxol et du desacetyl-10 taxol
FR2629819B1 (fr) 1988-04-06 1990-11-16 Rhone Poulenc Sante Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii
FR2629818B1 (fr) * 1988-04-06 1990-11-16 Centre Nat Rech Scient Procede de preparation du taxol
US5019504A (en) * 1989-03-23 1991-05-28 The United States Of America As Represented By The Secretary Of Agriculture Production of taxol or taxol-like compounds in cell culture
US5175315A (en) * 1989-05-31 1992-12-29 Florida State University Method for preparation of taxol using β-lactam
US5136060A (en) * 1989-11-14 1992-08-04 Florida State University Method for preparation of taxol using an oxazinone
US5380916A (en) 1990-11-02 1995-01-10 University Of Florida Method for the isolation and purification of taxane derivatives
MX9102128A (es) 1990-11-23 1992-07-08 Rhone Poulenc Rorer Sa Derivados de taxano,procedimiento para su preparacion y composicion farmaceutica que los contiene
US5279953A (en) * 1992-06-24 1994-01-18 Esca Genetics Corporation In vivo production of taxanes
FR2696463B1 (fr) * 1992-10-05 1994-11-25 Rhone Poulenc Rorer Sa Procédé d'obtention de la désacétyl-10 baccatine III.
FR2703049B1 (fr) * 1993-03-22 1995-04-21 Rhone Poulenc Rorer Sa Procédé de purification des taxoïdes.

Also Published As

Publication number Publication date
DE69307333T2 (de) 1997-04-30
US5736366A (en) 1998-04-07
DE69307333D1 (de) 1997-02-20
FI951590A0 (fi) 1995-04-04
NZ256449A (en) 1996-09-25
NO951281L (no) 1995-04-03
KR950703549A (ko) 1995-09-20
UA40601C2 (uk) 2001-08-15
NO310414B1 (no) 2001-07-02
CZ84495A3 (en) 1995-09-13
RU95110662A (ru) 1996-12-27
LT3465B (en) 1995-10-25
AU5115493A (en) 1994-04-26
GEP19981433B (en) 1998-10-30
SK280335B6 (sk) 1999-12-10
HUT72678A (en) 1996-05-28
CA2146248C (fr) 2006-12-12
ZA937312B (en) 1994-04-25
RU2108330C1 (ru) 1998-04-10
WO1994007881A1 (fr) 1994-04-14
EE03124B1 (et) 1998-10-15
SK43195A3 (en) 1995-08-09
PL173993B1 (pl) 1998-05-29
TW404944B (en) 2000-09-11
CZ286452B6 (en) 2000-04-12
CN1041310C (zh) 1998-12-23
EP0663909A1 (de) 1995-07-26
PL308243A1 (en) 1995-07-24
JP3299753B2 (ja) 2002-07-08
NO951281D0 (no) 1995-04-03
HU9500969D0 (en) 1995-06-28
CA2470124A1 (fr) 1994-04-14
GR3022229T3 (en) 1997-04-30
US5393896A (en) 1995-02-28
LV10620A (lv) 1995-04-20
CZ286593B6 (cs) 2000-05-17
CA2146248A1 (fr) 1994-04-14
LTIP1398A (en) 1994-11-25
CA2470124C (fr) 2007-08-07
JPH08501791A (ja) 1996-02-27
DK0663909T3 (de) 1997-01-27
MX9305770A (es) 1994-05-31
HU225969B1 (en) 2008-01-28
FR2696462B1 (fr) 1994-11-25
ES2095672T3 (es) 1997-02-16
FI951590A (fi) 1995-04-04
KR100301238B1 (ko) 2001-11-22
EP0663909B1 (de) 1997-01-08
AU680440B2 (en) 1997-07-31
CN1085552A (zh) 1994-04-20
FR2696462A1 (fr) 1994-04-08
ATE147381T1 (de) 1997-01-15
FI109797B (fi) 2002-10-15

Similar Documents

Publication Publication Date Title
LV10620B (en) Method for preparation of 10-deacethylbaccatine
PL308244A1 (en) Method of producing 10-desacetylobacantine iii
ATE273945T1 (de) Verfahren zur kristallisierung von sterisch gehinderten verbindungen
YU63602A (sh) Postupak za prečišćavanje fermentacionog bujona
HRP20050415B1 (en) A process for the purification of 1,4-butanediol mononitrate
JPS524650A (en) Purifying method for polluted water
FR2736355B1 (fr) Procede d'extraction et d'isolement de la 10-desacetylbaccatine iii
UA19295A (uk) СПОСІБ ОДЕРЖАHHЯ omega-ГІДРОПЕРФТОРАЛКАHО-ІЛФТОРИДІВ