ATE273945T1 - Verfahren zur kristallisierung von sterisch gehinderten verbindungen - Google Patents
Verfahren zur kristallisierung von sterisch gehinderten verbindungenInfo
- Publication number
- ATE273945T1 ATE273945T1 AT98945420T AT98945420T ATE273945T1 AT E273945 T1 ATE273945 T1 AT E273945T1 AT 98945420 T AT98945420 T AT 98945420T AT 98945420 T AT98945420 T AT 98945420T AT E273945 T1 ATE273945 T1 AT E273945T1
- Authority
- AT
- Austria
- Prior art keywords
- sterically hindered
- crystalizing
- solution
- hindered compounds
- crystallisation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B63/00—Purification; Separation; Stabilisation; Use of additives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/22—Separation; Purification; Stabilisation; Use of additives
- C07C231/24—Separation; Purification
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Inorganic Compounds Of Heavy Metals (AREA)
- Glass Compositions (AREA)
- Iron Core Of Rotating Electric Machines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Epoxy Compounds (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
- Cephalosporin Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9720969.6A GB9720969D0 (en) | 1997-10-02 | 1997-10-02 | Process |
| PCT/GB1998/002955 WO1999018054A1 (en) | 1997-10-02 | 1998-10-02 | Process for the crystallisation of sterically hindered compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE273945T1 true ATE273945T1 (de) | 2004-09-15 |
Family
ID=10819971
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98945420T ATE273945T1 (de) | 1997-10-02 | 1998-10-02 | Verfahren zur kristallisierung von sterisch gehinderten verbindungen |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US6646171B2 (de) |
| EP (1) | EP1025067B1 (de) |
| JP (1) | JP4509375B2 (de) |
| CN (1) | CN1129566C (de) |
| AT (1) | ATE273945T1 (de) |
| AU (1) | AU9274898A (de) |
| CA (1) | CA2305569A1 (de) |
| CZ (1) | CZ295010B6 (de) |
| DE (1) | DE69825772T2 (de) |
| ES (1) | ES2227875T3 (de) |
| GB (1) | GB9720969D0 (de) |
| NO (1) | NO323567B1 (de) |
| PT (1) | PT1025067E (de) |
| WO (1) | WO1999018054A1 (de) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6957220B2 (en) | 2000-11-07 | 2005-10-18 | Research Investment Networks, Inc. | System, method and article of manufacture for tracking and supporting the distribution of content electronically |
| ITMI20010773A1 (it) * | 2001-04-11 | 2002-10-11 | Chemi Spa | Processo per la produzione di ioexolo ad elevata purezza |
| NO338295B1 (no) * | 2004-08-09 | 2016-08-08 | Ge Healthcare As | Fremstilling av iodixanol. |
| NO20043305D0 (no) * | 2004-08-09 | 2004-08-09 | Amersham Health As | Preparation of lodixanol |
| NO342021B1 (no) * | 2005-07-29 | 2018-03-12 | Ge Healthcare As | Kontinuerlig krystalliseringsprosess |
| NO20053687D0 (no) * | 2005-07-29 | 2005-07-29 | Amersham Health As | Crystallisation Process. |
| NO20053676D0 (no) * | 2005-07-29 | 2005-07-29 | Amersham Health As | Crystallisation Process |
| NO20055643D0 (no) * | 2005-11-29 | 2005-11-29 | Amersham Health As | Preparation of lodixanol |
| WO2007065534A1 (de) * | 2005-12-05 | 2007-06-14 | Bayer Schering Pharma Aktiengesellschaft | Verfahren zur rückgewinnung von für pharmazeutische zwecke geeignetem iopromid aus mutterlaugen |
| DE102005059191B4 (de) * | 2005-12-05 | 2008-02-07 | Bayer Schering Pharma Ag | Verfahren zur Rückgewinnung von für pharmazeutische Zwecke geeignetem Iopromid aus Mutterlaugen |
| US7723544B2 (en) * | 2005-12-08 | 2010-05-25 | Bayer Schering Pharma Ag | Process for recovery of iopromide, suitable for pharmaceutical purposes, from mother liquors |
| EP1966110B1 (de) | 2005-12-19 | 2013-04-24 | Ge Healthcare As | Verfahren zur aufreinigung von iodixanol |
| CN101293855B (zh) * | 2007-04-27 | 2012-08-29 | 上海冠杰生物医药科技有限公司 | 一种碘克沙醇的纯化方法 |
| KR100976097B1 (ko) | 2008-12-05 | 2010-08-16 | 주식회사 대웅제약 | 이오프로마이드의 ｚ 이성체를 선택적으로 결정화하는 방법 |
| US7999134B2 (en) | 2009-07-21 | 2011-08-16 | Ge Healthcare As | Crystallization of iodixanol using milling |
| US8962887B2 (en) * | 2009-07-21 | 2015-02-24 | Ge Healthcare As | Synthesis of iodixanol in 1-methoxy-2-propanol and water or methanol |
| US7999135B2 (en) | 2009-07-21 | 2011-08-16 | Ge Healthcare As | Crystallization of iodixanol using ultrasound |
| US8969619B2 (en) | 2009-07-21 | 2015-03-03 | Ge Healthcare As | Synthesis of iodixanol in propyleneglycol |
| US8962886B2 (en) * | 2009-07-21 | 2015-02-24 | Ge Healthcare As | Synthesis of iodixanol in methanol |
| US7754918B1 (en) * | 2009-07-21 | 2010-07-13 | Ge Healthcare As | Crystallization of iodixanol in isopropanol and methanol |
| CN102079716B (zh) * | 2009-11-26 | 2014-03-05 | 浙江台州海神制药有限公司 | 碘克沙醇的制备与纯化 |
| JP5775524B2 (ja) * | 2009-11-26 | 2015-09-09 | アイマックス ダイアグノスティック イメージング ホールディング リミテッド | イオジキサノールの調製及び精製 |
| CN102875411A (zh) * | 2012-10-30 | 2013-01-16 | 广州牌牌生物科技有限公司 | 一种用大孔树脂分离纯化碘克沙醇注射剂原料的方法 |
| CN111777525B (zh) * | 2019-04-04 | 2021-08-27 | 成都西岭源药业有限公司 | 一种碘克沙醇的精制方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1548594A (en) * | 1976-06-11 | 1979-07-18 | Nyegaard & Co As | Triiodoisophthalic acid amides |
| DE3364536D1 (en) * | 1982-11-08 | 1986-08-21 | Nyegaard & Co As | X-ray contrast agents |
| IL110391A (en) * | 1993-07-30 | 1998-12-06 | Zambon Spa | Process for the formation of infamidol |
| DE4425340A1 (de) * | 1994-07-18 | 1994-12-01 | Ciba Geigy Ag | Sterisch gehinderte Amine in neuen kristallinen und amorphen Modifikationen |
| PT101720A (pt) * | 1995-06-08 | 1997-01-31 | Hovione Sociedade Quimica S A | Processo para a purificacao e cristalizacao de iopamidol |
-
1997
- 1997-10-02 GB GBGB9720969.6A patent/GB9720969D0/en not_active Ceased
-
1998
- 1998-10-02 CA CA002305569A patent/CA2305569A1/en not_active Abandoned
- 1998-10-02 WO PCT/GB1998/002955 patent/WO1999018054A1/en active IP Right Grant
- 1998-10-02 DE DE69825772T patent/DE69825772T2/de not_active Expired - Lifetime
- 1998-10-02 CN CN98809827A patent/CN1129566C/zh not_active Expired - Lifetime
- 1998-10-02 CZ CZ20001169A patent/CZ295010B6/cs not_active IP Right Cessation
- 1998-10-02 PT PT98945420T patent/PT1025067E/pt unknown
- 1998-10-02 JP JP2000514867A patent/JP4509375B2/ja not_active Expired - Lifetime
- 1998-10-02 AU AU92748/98A patent/AU9274898A/en not_active Abandoned
- 1998-10-02 ES ES98945420T patent/ES2227875T3/es not_active Expired - Lifetime
- 1998-10-02 EP EP98945420A patent/EP1025067B1/de not_active Expired - Lifetime
- 1998-10-02 AT AT98945420T patent/ATE273945T1/de not_active IP Right Cessation
-
2000
- 2000-03-22 NO NO20001470A patent/NO323567B1/no not_active IP Right Cessation
-
2001
- 2001-11-13 US US09/986,974 patent/US6646171B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| NO20001470L (no) | 2000-03-22 |
| CA2305569A1 (en) | 1999-04-15 |
| JP4509375B2 (ja) | 2010-07-21 |
| JP2001519320A (ja) | 2001-10-23 |
| CN1273574A (zh) | 2000-11-15 |
| AU9274898A (en) | 1999-04-27 |
| US20020072639A1 (en) | 2002-06-13 |
| CN1129566C (zh) | 2003-12-03 |
| EP1025067B1 (de) | 2004-08-18 |
| DE69825772D1 (de) | 2004-09-23 |
| ES2227875T3 (es) | 2005-04-01 |
| US6646171B2 (en) | 2003-11-11 |
| EP1025067A1 (de) | 2000-08-09 |
| WO1999018054A1 (en) | 1999-04-15 |
| DE69825772T2 (de) | 2005-08-25 |
| GB9720969D0 (en) | 1997-12-03 |
| PT1025067E (pt) | 2004-11-30 |
| NO20001470D0 (no) | 2000-03-22 |
| CZ20001169A3 (cs) | 2000-09-13 |
| NO323567B1 (no) | 2007-06-11 |
| CZ295010B6 (cs) | 2005-05-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE273945T1 (de) | Verfahren zur kristallisierung von sterisch gehinderten verbindungen | |
| DE69307333T2 (de) | Verfahren zur gewinnung von 10-deacetylbaccatin-iii | |
| HUP9800266A2 (hu) | Eljárás szerves vegyületek kinyerésére oldataikból | |
| ATE318255T1 (de) | Verfahren zur herstellung von estern | |
| ATE227272T1 (de) | Verfahren zur gewinnung von enantiomeren von cis- olirtin | |
| DK0922066T3 (da) | Polymere fortykkelsesmidler til vandige sammensætninger | |
| ATE187168T1 (de) | Verfahren zur herstellung von 1-substituierten 2- cyanoimidazolen | |
| DE69705321D1 (de) | Verfahren zur reinigung von acrylnitril | |
| DE3765524D1 (de) | Verbessertes verfahren zur herstellung von metallorganischen verbindungen. | |
| EA199900327A1 (ru) | Способ получения поликапролактама | |
| ATE269863T1 (de) | Verfahren zur herstellung von granisetron | |
| JPS524650A (en) | Purifying method for polluted water | |
| DE59309480D1 (de) | Verfahren zur herstellung einer physikalisch stabilen, kristallinen gamma-modifikation von para-aminobenzolsulfonamid | |
| DE69615562D1 (de) | Verfahren zu extrahieren und isolierung von 10-desacetylbachatin iii | |
| ATE292526T1 (de) | Verfahren zur entfernung von verunreinigungen aus feuchten böden | |
| NO873817D0 (no) | Fremgangsmaate ved fremstilling av alkoholer. | |
| DE59603757D1 (de) | Verfahren zur Herstellung von kristallinem O-Isopropylisoharnstoff-hydrochlorid | |
| Keri et al. | Method of purifying statins from a fermentation broth | |
| JPS53114254A (en) | Method for biological denitrification of night soil waste water |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |