LV10538B - Method for testing of immunological binding substance in biological liquid and diagnostically remedy - Google Patents

Method for testing of immunological binding substance in biological liquid and diagnostically remedy Download PDF

Info

Publication number
LV10538B
LV10538B LVP-93-465A LV930465A LV10538B LV 10538 B LV10538 B LV 10538B LV 930465 A LV930465 A LV 930465A LV 10538 B LV10538 B LV 10538B
Authority
LV
Latvia
Prior art keywords
igg
specific
hjih
aggregates
mak33
Prior art date
Application number
LVP-93-465A
Other languages
English (en)
Latvian (lv)
Other versions
LV10538A (lv
Inventor
Helmut Lenz
Ellen Missner
Werner Stock
Norbert Franken
Crance Mccarthy
Albert Rider
Harald Haug
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of LV10538A publication Critical patent/LV10538A/xx
Publication of LV10538B publication Critical patent/LV10538B/lv

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G01N33/6857—Antibody fragments
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/824—Immunological separation techniques
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/825—Pretreatment for removal of interfering factors from sample
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25125—Digestion or removing interfering materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Electrotherapy Devices (AREA)
  • Medicinal Preparation (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Steroid Compounds (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
LVP-93-465A 1988-03-03 1993-06-02 Method for testing of immunological binding substance in biological liquid and diagnostically remedy LV10538B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/164,054 US4914040A (en) 1988-03-03 1988-03-03 Reagent and method for determination of a polyvalent substance using an immunoaggregate

Publications (2)

Publication Number Publication Date
LV10538A LV10538A (lv) 1995-02-20
LV10538B true LV10538B (en) 1995-12-20

Family

ID=22592781

Family Applications (1)

Application Number Title Priority Date Filing Date
LVP-93-465A LV10538B (en) 1988-03-03 1993-06-02 Method for testing of immunological binding substance in biological liquid and diagnostically remedy

Country Status (18)

Country Link
US (1) US4914040A (xx)
EP (1) EP0331068B1 (xx)
JP (1) JPH0823560B2 (xx)
AT (1) ATE82072T1 (xx)
AU (1) AU616484B2 (xx)
CA (1) CA1340572C (xx)
DD (1) DD280396A5 (xx)
DE (2) DE3905505A1 (xx)
DK (1) DK175429B1 (xx)
ES (1) ES2045216T3 (xx)
FI (1) FI92879C (xx)
GR (1) GR3006991T3 (xx)
HU (1) HU212322B (xx)
IE (1) IE62974B1 (xx)
LV (1) LV10538B (xx)
PT (1) PT89889B (xx)
RU (1) RU2032906C1 (xx)
ZA (1) ZA891568B (xx)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3730059A1 (de) * 1987-09-08 1989-03-30 Behringwerke Ag Verfahren zur bestimmung von "loeslichem" fibrin
US5141853A (en) * 1988-07-22 1992-08-25 Abbott Laboratories Determination of ammonia levels in a sample
DE3829245A1 (de) * 1988-08-29 1990-03-01 Boehringer Mannheim Gmbh Verfahren zur bestimmung einer spezifisch bindefaehigen substanz
WO1991006559A1 (en) * 1989-10-24 1991-05-16 E.I. Du Pont De Nemours And Company Use of polymerized immunoglobulin to reduce the incidence of false-positive responses in immunoassays
US6274325B1 (en) 1990-06-25 2001-08-14 Boehringer Mannheim Gmbh Method for carrying out a homogeneous-immunoassay based on agglutination
DE4020204A1 (de) * 1990-06-25 1992-01-02 Boehringer Mannheim Gmbh Durchfuehrung eines homogenen immunoassays nach dem agglutinationsprinzip
JPH04350559A (ja) * 1991-05-28 1992-12-04 Dai Ichi Pure Chem Co Ltd 特異抗体の測定法
DE69217957T2 (de) * 1991-07-26 1997-08-07 Dade Chemistry Systems Inc Verfahren zur beseitigung von falschen ergebnissen in einem immunoassay
US5460944A (en) * 1991-10-28 1995-10-24 Boehringer Mannheim Gmbh Storable protein solution
DE4202923A1 (de) * 1992-02-01 1993-08-05 Behringwerke Ag Verfahren zur bestimmung von antigenen oder antikoerpern in gegenwart eines immunkomplexes
IL102495A (en) * 1992-07-14 1998-06-15 Patchornik Avraham Universal standard reagents, method of preparing same and use thereof
IL106887A (en) * 1993-09-02 1997-02-18 Yissum Res Dev Co Pharmaceutical and diagnostic compositions and a method for drug targeting
GB9403215D0 (en) * 1994-02-19 1994-04-13 Kodak Ltd Chemical modification of antibodies and antigens
DE4407423A1 (de) * 1994-03-05 1995-09-07 Boehringer Mannheim Gmbh Entstörmittel zum Einsatz bei Immunoassays
US5863740A (en) * 1994-03-05 1999-01-26 Boehringer Mannheim Gmbh Interference eliminating agent for application in immunoassays
DE4439452A1 (de) * 1994-11-04 1996-05-09 Boehringer Mannheim Gmbh Antikörperklassenspezifisches Entstörungsreagenz
DE19621133A1 (de) * 1996-05-24 1997-11-27 Boehringer Mannheim Gmbh Bestimmungsverfahren mit oligomerisierten Rezeptoren
DE19731465A1 (de) 1997-07-22 1999-01-28 Boehringer Mannheim Gmbh Verwendung von Kontrollflächen zur Detektion von Störproben in einem Nachweisverfahren
EP0922958B1 (de) * 1997-12-11 2002-10-02 Roche Diagnostics GmbH Entstörung von diagnostischen Verfahren durch Peptide aus D-Aminosäuren
DE19828466A1 (de) * 1998-06-26 1999-12-30 Roche Diagnostics Gmbh Entstörung von Immunoassays durch Substanzen, die aus den Framework-Regionen von Antikörpern abgeleitet sind
US6406858B1 (en) * 1998-11-27 2002-06-18 Bayer Corporation System for the reduction of interferences in immunoassays
EP1320753A2 (en) * 2000-09-25 2003-06-25 Abbott Laboratories Methods and kits for decreasing interferences of assay samples containing plasma or serum in specific binding assays by using a large polycation
DE10059720A1 (de) 2000-11-30 2002-06-06 Roche Diagnostics Gmbh Verwendung intramolekular kovalent vernetzter Proteine als Bindepartner in Immunoassays
DE10064827A1 (de) 2000-12-22 2002-06-27 Dade Behring Marburg Gmbh Nachweisverfahren
US20040091952A1 (en) * 2002-07-25 2004-05-13 Sysmex Corporation Reagent kit for detecting lupus anticoagulant
US20040018556A1 (en) * 2002-07-29 2004-01-29 Cantor Thomas L. Reagent and method for determination of a substance using an immunoaggregator
DE602004016906D1 (de) * 2003-03-28 2008-11-20 Sysmex Corp Reagenz zum Nachweis von anti-Phospholipid Antikörper
AU2004254140A1 (en) * 2003-07-08 2005-01-13 Inverness Medical Switzerland Gmbh Particle agglutination detection method and device
US20050112586A1 (en) * 2003-11-24 2005-05-26 Roland Janzen Method and composition for stabilizing liquid reagents
EP1562047B1 (en) * 2004-02-06 2008-05-14 Sysmex Corporation Reagent kit for detecting lupus anticoagulant
WO2005121795A1 (ja) * 2004-06-14 2005-12-22 Kyowa Medex Co., Ltd. 非特異反応が抑制された免疫測定方法および試薬
WO2006051548A2 (en) * 2004-11-15 2006-05-18 Inverness Medical Switzerland Gmbh Blood type method system and device
US7172906B2 (en) * 2004-11-16 2007-02-06 Dade Behring Inc. Reduction of non-specific binding in assays
KR101491700B1 (ko) * 2007-08-23 2015-02-11 가부시키가이샤 엘에스아이 메디엔스 비특이반응 억제제
US8956859B1 (en) 2010-08-13 2015-02-17 Aviex Technologies Llc Compositions and methods for determining successful immunization by one or more vaccines
WO2019207115A1 (en) * 2018-04-26 2019-10-31 Statens Serum Institut Improved immunoassays
CN109342743B (zh) * 2018-12-05 2022-02-18 菲鹏生物股份有限公司 一种能够与类风湿因子高效结合的变性IgG的制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0083869B1 (en) * 1982-01-05 1985-10-16 International Institute Of Cellular And Molecular Pathology (Icp) Method of immunoassay
DE3206729A1 (de) * 1982-02-25 1983-09-01 Behringwerke Ag, 3550 Marburg Immunologisches agglutinationsverfahren
DE3225027A1 (de) * 1982-07-05 1984-01-05 Boehringer Mannheim Gmbh, 6800 Mannheim Immunchemisches messverfahren
US4659678A (en) * 1982-09-29 1987-04-21 Serono Diagnostics Limited Immunoassay of antigens
US4474892A (en) * 1983-02-16 1984-10-02 Board Of Trustees Of The Leland Stanford Junior University Two-site immunoassays using monoclonal antibodies of different classes or subclasses and test kits for performing same
US4582810A (en) * 1983-09-30 1986-04-15 Becton, Dickinson And Company Immuno-agglutination particle suspensions
JPS60256057A (ja) * 1984-06-01 1985-12-17 Dai Ichi Pure Chem Co Ltd 免疫学的測定法
JPS6165162A (ja) * 1984-09-05 1986-04-03 Chemo Sero Therapeut Res Inst モノクロ−ナル抗体を用いた免疫学的測定方法における非特異反応吸収剤
JPH0799372B2 (ja) * 1985-07-13 1995-10-25 富士レビオ株式会社 逆受身凝集反応用非特異反応吸収剤

Also Published As

Publication number Publication date
ES2045216T3 (es) 1994-01-16
JPH01254869A (ja) 1989-10-11
AU3090889A (en) 1989-09-07
EP0331068A1 (de) 1989-09-06
DE58902586D1 (de) 1992-12-10
RU2032906C1 (ru) 1995-04-10
DK96689D0 (da) 1989-02-28
DK96689A (da) 1989-09-04
LV10538A (lv) 1995-02-20
DE3905505A1 (de) 1989-09-14
DK175429B1 (da) 2004-10-18
US4914040A (en) 1990-04-03
FI891012A0 (fi) 1989-03-02
GR3006991T3 (xx) 1993-06-30
HU212322B (en) 1996-05-28
CA1340572C (en) 1999-06-01
HUT50988A (en) 1990-03-28
ZA891568B (en) 1989-11-29
AU616484B2 (en) 1991-10-31
DD280396A5 (de) 1990-07-04
PT89889B (pt) 1994-05-31
JPH0823560B2 (ja) 1996-03-06
IE62974B1 (en) 1995-03-08
FI891012A (fi) 1989-09-04
FI92879C (fi) 1995-01-10
PT89889A (pt) 1989-11-10
ATE82072T1 (de) 1992-11-15
FI92879B (fi) 1994-09-30
EP0331068B1 (de) 1992-11-04
IE890683L (en) 1989-09-03

Similar Documents

Publication Publication Date Title
LV10538B (en) Method for testing of immunological binding substance in biological liquid and diagnostically remedy
US10761091B2 (en) Interference-suppressed immunoassay to detect anti-drug antibodies in serum samples
JP3443891B2 (ja) タンパク質吸着防止剤
CN111417856B (zh) 抑制靶干扰作用的抗药物抗体测定法
KR101353930B1 (ko) 신규한 항원의 검출방법 및 그를 이용한 장치
EP2380593A1 (en) Stabilizing labeled antibody using amino acids
JP4241301B2 (ja) 免疫学的測定用試薬
JP4486059B2 (ja) 免疫測定用ラテックス組成物
GB1564987A (en) Stable immunological reagents
US11719695B2 (en) Immunoassay method to prevent inhibition of antigen-antibody binding interactions in mucosal fluids
NZ210990A (en) Stabilised enzyme conjugate compositions containing polyethylene glycol
JPH0467150B2 (xx)
Bitsch An investigation into the basic virus-antibody neutralization reaction, with special regard to the reaction in the constant-virus/varying-serum neutralization test
Zhu-Shimoni et al. Trace level analysis of leached Protein A in bioprocess samples without interference from the large excess of rhMAb IgG
HU et al. Studies on the Optimal Immunization Schedule of Experimental Animals. VI.: Antigen Dose-Response of Aluminum Hydroxide-Aided Immunization and Booster Effect under Low Antigen Dose
JP2015184125A (ja) 非特異的反応を抑制した免疫学的測定方法
CA2414704A1 (en) Tertiary amine compounds for use in immunoassays
WO2019207115A1 (en) Improved immunoassays
US6890711B1 (en) Titration method for a complex viral composition
JP2545503B2 (ja) 免疫学的診断試薬
JPH11295313A (ja) 抗体または抗体断片の重合体とその利用
JP2000292427A (ja) 抗原もしくは抗体の測定法および試薬
Saadalla et al. Diagnostic Utility of High Dose Heparin Confirmation Step in Heparin Induced Thrombocytopenia ELISA Assay
JPH1169996A (ja) 発色方法、該方法を用いる酵素免疫測定法及びイムノクロマト法
Milgrom et al. Complement Fixation‐Mixed Agglutination Test in Cell Cultures 1