LUC00071I2 - - Google Patents
Download PDFInfo
- Publication number
- LUC00071I2 LUC00071I2 LU00071C LUC00071C LUC00071I2 LU C00071 I2 LUC00071 I2 LU C00071I2 LU 00071 C LU00071 C LU 00071C LU C00071 C LUC00071 C LU C00071C LU C00071 I2 LUC00071 I2 LU C00071I2
- Authority
- LU
- Luxembourg
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/08—Antiseborrheics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
- G01N33/567—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds utilising isolate of tissue or organ as binding agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Dermatology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Mycology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Rheumatology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Wood Science & Technology (AREA)
- Endocrinology (AREA)
- General Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Cardiology (AREA)
- Pulmonology (AREA)
- Oncology (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US75488905P | 2005-12-29 | 2005-12-29 |
Publications (1)
Publication Number | Publication Date |
---|---|
LUC00071I2 true LUC00071I2 (fr) | 2018-06-28 |
Family
ID=38218878
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
LU00071C LUC00071I2 (fr) | 2005-12-29 | 2018-04-25 |
Country Status (37)
Country | Link |
---|---|
US (10) | US7935344B2 (fr) |
EP (4) | EP2548577B1 (fr) |
JP (1) | JP5193881B2 (fr) |
KR (1) | KR101210395B1 (fr) |
CN (2) | CN102887954B (fr) |
AU (1) | AU2006330411B2 (fr) |
BR (1) | BRPI0620946B8 (fr) |
CA (1) | CA2635692C (fr) |
CR (1) | CR10181A (fr) |
CY (4) | CY1115935T1 (fr) |
DK (3) | DK3219328T3 (fr) |
EA (2) | EA035459B1 (fr) |
EC (1) | ECSP088591A (fr) |
ES (3) | ES2622602T3 (fr) |
GT (1) | GT200800132A (fr) |
HK (1) | HK1124548A1 (fr) |
HN (1) | HN2008000988A (fr) |
HR (3) | HRP20140982T1 (fr) |
HU (3) | HUE034269T2 (fr) |
IL (5) | IL192458A (fr) |
LT (3) | LT2548577T (fr) |
LU (1) | LUC00071I2 (fr) |
MX (2) | MX2008008621A (fr) |
MY (2) | MY162559A (fr) |
NI (1) | NI200800193A (fr) |
NL (1) | NL300935I2 (fr) |
NO (5) | NO20240354A1 (fr) |
NZ (1) | NZ569546A (fr) |
PL (3) | PL2548577T3 (fr) |
PT (3) | PT2548577T (fr) |
RS (3) | RS53685B1 (fr) |
SG (1) | SG10201505755YA (fr) |
SI (3) | SI3219328T1 (fr) |
SV (1) | SV2008002972A (fr) |
UA (1) | UA101301C2 (fr) |
WO (1) | WO2007076524A2 (fr) |
ZA (1) | ZA200806556B (fr) |
Families Citing this family (113)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7090847B1 (en) | 1999-09-09 | 2006-08-15 | Schering Corporation | Mammalian cytokines; related reagents and methods |
CA2613818C (fr) | 2005-06-30 | 2013-08-27 | Centocor, Inc. | Anticorps anti-il-23, compositions, methodes et utilisations |
PL1937721T3 (pl) * | 2005-08-25 | 2010-12-31 | Lilly Co Eli | Przeciwciała anty-IL23 |
SG165322A1 (en) | 2005-08-31 | 2010-10-28 | Schering Corp | Engineered anti-il-23 antibodies |
CN101296706B (zh) | 2005-09-01 | 2011-11-30 | 先灵公司 | Il-23和il-17拮抗剂治疗自身免疫性眼部炎性疾病的用途 |
EA035459B1 (ru) | 2005-12-29 | 2020-06-19 | Сентокор, Инк. | Антитело против il-23p19 |
US7910703B2 (en) | 2006-03-10 | 2011-03-22 | Zymogenetics, Inc. | Antagonists to IL-17A, IL-17F, and IL-23P19 and methods of use |
WO2007147019A2 (fr) | 2006-06-13 | 2007-12-21 | Zymogenetics, Inc. | Antagonistes d'il-17 et d'il-23 et leurs procédés d'utilisation |
TWI426918B (zh) | 2007-02-12 | 2014-02-21 | Merck Sharp & Dohme | Il-23拮抗劑於治療感染之用途 |
EP2426145B1 (fr) | 2007-02-23 | 2017-01-18 | Merck Sharp & Dohme Corp. | Anticorps anti-23p19 de synthèse |
PL2426144T3 (pl) | 2007-02-23 | 2019-05-31 | Merck Sharp & Dohme | Przeciwciała Anty-IL-23p19 wytworzone metodą inżynierii genetycznej |
WO2008106131A2 (fr) | 2007-02-28 | 2008-09-04 | Schering Corporation | Polythérapie pour le traitement de troubles immunitaires |
EP2203476B1 (fr) * | 2007-09-25 | 2016-10-26 | Genzyme Corporation | Compositions et procédés pour inhiber les voies d'interleukines |
JP2011504740A (ja) | 2007-11-27 | 2011-02-17 | アブリンクス エン.ヴェー. | ヘテロ二量体サイトカイン及び/又はこれらの受容体に指向性を有するアミノ酸配列、並びにこれを含むポリペプチド |
LT2708559T (lt) | 2008-04-11 | 2018-06-11 | Chugai Seiyaku Kabushiki Kaisha | Antigeną surišanti molekulė, galinti pakartotinai prisijungti prie dviejų ar daugiau antigeno molekulių |
EP2331078B1 (fr) | 2008-08-27 | 2012-09-19 | Merck Sharp & Dohme Corp. | Formulations lyophilisees d'anticorps anti-il-23p19 modifies |
TWI440469B (zh) | 2008-09-26 | 2014-06-11 | Chugai Pharmaceutical Co Ltd | Improved antibody molecules |
US20110020392A1 (en) * | 2008-10-14 | 2011-01-27 | Salubrious Pharmaceutical, Llc | Process for treatment of rheumatoid arthritis, tremors/parkinson's disease, multiple sclerosis and non-viral based cancers |
WO2010036226A1 (fr) * | 2008-09-26 | 2010-04-01 | George Nelson | Méthode de traitement de la polyarthrite rhumatoïde, des tremblements/de la maladie de parkinson et de la sclérose en plaques |
CA2745218A1 (fr) | 2008-12-19 | 2010-06-24 | Schering Corporation | Supplement alimentaire pour culture de cellules de mammifere et procedes d'utilisation |
WO2011017294A1 (fr) | 2009-08-07 | 2011-02-10 | Schering Corporation | Anticorps anti-rankl humain |
JO3244B1 (ar) | 2009-10-26 | 2018-03-08 | Amgen Inc | بروتينات ربط مستضادات il – 23 البشرية |
CN102905727B (zh) | 2009-10-30 | 2016-12-07 | 詹森生物科技公司 | Il-17a拮抗剂 |
GB201013975D0 (en) | 2010-08-20 | 2010-10-06 | Imp Innovations Ltd | Method of treating desease |
WO2011079004A1 (fr) | 2009-12-23 | 2011-06-30 | Schering Corporation | Lignée cellulaire 3m |
US20110311527A1 (en) | 2010-06-16 | 2011-12-22 | Allergan, Inc. | IL23p19 ANTIBODY INHIBITOR FOR TREATING OCULAR AND OTHER CONDITIONS |
CN103261223B (zh) | 2010-10-13 | 2017-03-29 | 詹森生物科技公司 | 人制瘤素m抗体及使用方法 |
JP6126532B2 (ja) | 2010-11-04 | 2017-05-10 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 抗il−23抗体 |
EP2647706B1 (fr) | 2010-11-30 | 2023-05-17 | Chugai Seiyaku Kabushiki Kaisha | Molécule de liaison à l'antigène, apte à se lier de façon répétée à une pluralité de molécules d'antigène |
MX352889B (es) | 2011-02-25 | 2017-12-13 | Chugai Pharmaceutical Co Ltd | Anticuerpo de fc especifico para fcyriib. |
US20150050269A1 (en) | 2011-09-30 | 2015-02-19 | Chugai Seiyaku Kabushiki Kaisha | Antigen-binding molecule promoting disappearance of antigens having plurality of biological activities |
TW201817745A (zh) | 2011-09-30 | 2018-05-16 | 日商中外製藥股份有限公司 | 具有促進抗原清除之FcRn結合域的治療性抗原結合分子 |
CN109206516A (zh) | 2012-05-03 | 2019-01-15 | 勃林格殷格翰国际有限公司 | 抗IL-23p19抗体 |
US9803010B2 (en) | 2012-06-27 | 2017-10-31 | Merck Sharp & Dohme Corp. | Crystalline anti-human IL-23p19 antibodies |
RU2015125343A (ru) * | 2012-11-29 | 2017-01-11 | БАЙЕР ХелсКер ЛЛСи | Гуманизированные моноклональные антитела против активированного белка с и их применение |
UA117466C2 (uk) | 2012-12-13 | 2018-08-10 | Мерк Шарп Енд Доме Корп. | СТАБІЛЬНИЙ СКЛАД У ВИГЛЯДІ РОЗЧИНУ АНТИТІЛА ДО IL-23p19 |
US9113892B2 (en) | 2013-01-08 | 2015-08-25 | Covidien Lp | Surgical clip applier |
JOP20140049B1 (ar) | 2013-03-08 | 2021-08-17 | Lilly Co Eli | أجسام مضادة ترتبط بـ il-23 |
JP2016517408A (ja) | 2013-03-15 | 2016-06-16 | アムジェン インコーポレイテッド | 抗il−23抗体を用いた乾癬の治療方法 |
CN105307675A (zh) | 2013-03-15 | 2016-02-03 | 美国安进公司 | 使用抗il23抗体治疗克罗恩氏病的方法 |
EP3415534A1 (fr) | 2013-05-10 | 2018-12-19 | Numab Therapeutics AG | Constructions bispécifiques et leur utilisation dans le traitement de plusieurs maladies |
US9801900B2 (en) | 2013-11-22 | 2017-10-31 | Mary Kay Inc. | Compositions for sensitive skin |
WO2015114426A2 (fr) * | 2014-01-30 | 2015-08-06 | Massimo Zanotti | Procédé de contrôle du respect du bien-être des volailles vivantes destinées à l'abattage |
WO2015120389A1 (fr) | 2014-02-10 | 2015-08-13 | Patara Pharma, LLC | Traitement utilisant des stabilisateurs de mastocytes pour des troubles systémiques |
PT3104854T (pt) | 2014-02-10 | 2020-06-26 | Respivant Sciences Gmbh | Estabilizadores de mastócitos para tratamento de doença pulmonar |
US10507241B2 (en) | 2014-07-24 | 2019-12-17 | Boehringer Ingelheim International Gmbh | Biomarkers useful in the treatment of IL-23A related diseases |
TWI711629B (zh) | 2014-09-03 | 2020-12-01 | 德商包林格因蓋爾漢國際股份有限公司 | 靶向IL-23A與TNF-α之化合物及其用途 |
AR102417A1 (es) | 2014-11-05 | 2017-03-01 | Lilly Co Eli | Anticuerpos biespecíficos anti-tnf- / anti-il-23 |
MY183415A (en) | 2014-12-19 | 2021-02-18 | Chugai Pharmaceutical Co Ltd | Anti-c5 antibodies and methods of use |
SG11201700841QA (en) | 2014-12-19 | 2017-03-30 | Chugai Pharmaceutical Co Ltd | Anti-myostatin antibodies, polypeptides containing variant fc regions, and methods of use |
IL307578A (en) | 2015-02-04 | 2023-12-01 | Boehringer Ingelheim Int | Methods for treating inflammatory diseases |
KR102605798B1 (ko) | 2015-02-05 | 2023-11-23 | 추가이 세이야쿠 가부시키가이샤 | 이온 농도 의존적 항원 결합 도메인을 포함하는 항체, Fc 영역 개변체, IL-8에 결합하는 항체, 및 그들의 사용 |
BR112017014067B1 (pt) | 2015-02-27 | 2021-01-12 | Chugai Seiyaku Kabushiki Kaisha | usos de um anticorpo receptor de il-6 para no tratamento de doenças relacionadas a il-6 |
EP3685856A1 (fr) | 2015-04-14 | 2020-07-29 | Boehringer Ingelheim International GmbH | Procédés de traitement de maladies |
WO2017027387A1 (fr) | 2015-08-07 | 2017-02-16 | Patara Pharma, LLC | Méthodes de traitement de troubles liés aux mastocytes par des stabilisateurs de mastocytes |
WO2017027402A1 (fr) | 2015-08-07 | 2017-02-16 | Patara Pharma, LLC | Méthodes de traitement de troubles systémiques aptes à être traités par des stabilisateurs de mastocytes, y compris de troubles liés aux mastocytes |
CA2998349A1 (fr) | 2015-09-17 | 2017-03-23 | Amgen Inc. | Prediction de reponse clinique a des antagonistes d'il23 utilisant des biomarqueurs de la voie de l'il23 |
TWI733695B (zh) | 2015-09-18 | 2021-07-21 | 德商百靈佳殷格翰國際股份有限公司 | 治療發炎性疾病之方法 |
WO2017087391A1 (fr) | 2015-11-17 | 2017-05-26 | Bayer Healthcare, Llc | Épitope d'anticorps monoclonaux humanisés optimisés dirigés contre la protéine c activée et leurs utilisations |
JP2019508370A (ja) | 2015-12-22 | 2019-03-28 | アムジェン インコーポレイテッド | Il23アンタゴニストに対する臨床応答の予測因子としてのccl20 |
US11359009B2 (en) | 2015-12-25 | 2022-06-14 | Chugai Seiyaku Kabushiki Kaisha | Anti-myostatin antibodies and methods of use |
EA201892190A1 (ru) | 2016-03-29 | 2019-04-30 | Янссен Байотек, Инк. | Лечение псориаза антителом к ил-12 и/или ил-23 с возрастанием интервала между введениями дозы |
EP4410997A2 (fr) | 2016-04-15 | 2024-08-07 | Boehringer Ingelheim International GmbH | Méthodes de traitement de maladies inflammatoires |
MX2019001448A (es) | 2016-08-05 | 2019-09-13 | Chugai Pharmaceutical Co Ltd | Composicion para profilaxis o tratamiento de enfermedades relacionadas con interleucina 8 (il-8). |
EP3506893A4 (fr) | 2016-08-31 | 2020-01-22 | Respivant Sciences GmbH | Compositions de cromolyne pour le traitement de la toux chronique due à une fibrose pulmonaire idiopathique |
CA3037961A1 (fr) * | 2016-09-30 | 2018-04-05 | Janssen Biotech, Inc. | Procede sur et efficace de traitement du psoriasis avec un anticorps specifique contre l'il-23 |
AU2017339366A1 (en) | 2016-10-07 | 2019-04-11 | Respivant Sciences Gmbh | Cromolyn compositions for treatment of pulmonary fibrosis |
EP3677597A1 (fr) | 2016-10-14 | 2020-07-08 | Boehringer Ingelheim International GmbH | Procédés de traitement de maladies |
KR20190078648A (ko) | 2016-11-16 | 2019-07-04 | 얀센 바이오테크 인코포레이티드 | 항-il23 특이적 항체로 건선을 치료하는 방법 |
US11840565B2 (en) | 2016-12-29 | 2023-12-12 | University Of Miami | Methods and compositions for treating virus-associated inflammation |
JP7191833B2 (ja) | 2017-01-30 | 2022-12-19 | 中外製薬株式会社 | 抗スクレロスチン抗体およびその使用 |
JOP20190260A1 (ar) | 2017-05-02 | 2019-10-31 | Merck Sharp & Dohme | صيغ ثابتة لأجسام مضادة لمستقبل الموت المبرمج 1 (pd-1) وطرق استخدامها |
BR112019022873A8 (pt) | 2017-05-02 | 2023-04-11 | Merck Sharp & Dohme | Formulação, e, vaso ou dispositivo de injeção. |
JP7185884B2 (ja) | 2017-05-02 | 2022-12-08 | 国立研究開発法人国立精神・神経医療研究センター | Il-6及び好中球の関連する疾患の治療効果の予測及び判定方法 |
EP3459968A1 (fr) * | 2017-09-20 | 2019-03-27 | Numab Innovation AG | Nouvelles combinaisons de structure de domaines variables d'anticorps stables |
TW201922780A (zh) | 2017-09-25 | 2019-06-16 | 美商健生生物科技公司 | 以抗il12/il23抗體治療狼瘡之安全且有效之方法 |
MX2020009265A (es) * | 2018-03-05 | 2020-10-01 | Janssen Biotech Inc | Metodos para tratar la enfermedad de crohn con un anticuerpo especifico anti-il23. |
TWI744617B (zh) | 2018-03-30 | 2021-11-01 | 美商美國禮來大藥廠 | 治療潰瘍性結腸炎之方法 |
US20190345245A1 (en) | 2018-05-11 | 2019-11-14 | Janssen Biotech, Inc. | Methods of Treating Crohn's Disease with Anti-IL23 Specific Antibody |
EP3820897A2 (fr) | 2018-07-13 | 2021-05-19 | Astrazeneca Collaboration Ventures, LLC | Traitement de la rectocolite hémorragique au moyen de brazikumab |
US20200025776A1 (en) | 2018-07-18 | 2020-01-23 | Janssen Biotech, Inc. | Sustained Response Predictors After Treatment With Anti-IL23 Specific Antibody |
US20200061015A1 (en) | 2018-08-23 | 2020-02-27 | Janssen Biotech, Inc. | Lipase Degradation Resistant Surfactants for Use in Large Molecule Therapeutic Formulations |
BR112021007765A2 (pt) * | 2018-10-23 | 2021-08-03 | Scholar Rock, Inc. | inibidores seletivos de rgmc e uso dos mesmos |
AU2019383017A1 (en) | 2018-11-20 | 2021-06-03 | Janssen Biotech, Inc. | Safe and effective method of treating psoriasis with anti-IL-23 specific antibody |
TWI779253B (zh) | 2018-11-27 | 2022-10-01 | 大陸商信達生物製藥(蘇州)有限公司 | 抗IL-23p19抗體及其用途 |
US20200197517A1 (en) | 2018-12-18 | 2020-06-25 | Janssen Biotech, Inc. | Safe and Effective Method of Treating Lupus with Anti-IL12/IL23 Antibody |
BR112021015034A2 (pt) | 2019-02-18 | 2021-10-05 | Eli Lilly And Company | Formulação de anticorpo terapêutico |
EP3938384A4 (fr) | 2019-03-14 | 2022-12-28 | Janssen Biotech, Inc. | Méthodes de fabrication permettant de produire des compositions d'anticorps anti-il12/il23 |
CA3138241A1 (fr) | 2019-05-23 | 2020-11-26 | Janssen Biotech, Inc. | Methode de traitement de maladie intestinale inflammatoire au moyen d'une polytherapie d'anticorps diriges contre il -23 et tnf alpha |
CN110564694B (zh) * | 2019-09-23 | 2021-07-13 | 华东师范大学 | 分泌il-23抗体的靶向前列腺癌的car-t细胞药物 |
CN115135671A (zh) | 2019-12-20 | 2022-09-30 | 新石生物制药有限公司 | 抗白介素-23 p19的抗体及其使用方法 |
KR20230006551A (ko) * | 2020-05-05 | 2023-01-10 | 얀센 바이오테크 인코포레이티드 | 항-il23 특이적 항체로 크론병을 치료하는 방법 |
WO2021228113A1 (fr) * | 2020-05-13 | 2021-11-18 | 信达生物制药(苏州)有限公司 | Préparation comprenant un anticorps anti-il-23p19, son procédé de préparation et son utilisation |
CN112807428B (zh) * | 2020-06-12 | 2024-08-27 | 江苏荃信生物医药股份有限公司 | 包含抗人白介素23单克隆抗体的药物组合物 |
AR123477A1 (es) | 2020-09-10 | 2022-12-07 | Lilly Co Eli | Formulaciones de anticuerpos terapéuticos |
WO2022190034A1 (fr) | 2021-03-12 | 2022-09-15 | Janssen Biotech, Inc. | Méthode de traitement de patients souffrant de polyarthrite psoriasique ayant une réponse inadéquate à une thérapie par tnf avec un anticorps spécifique anti-il23 |
US11278709B1 (en) | 2021-03-12 | 2022-03-22 | Pocket Naloxone Corp. | Drug delivery device and methods for using same |
US20220298236A1 (en) | 2021-03-12 | 2022-09-22 | Janssen Biotech, Inc. | Safe and Effective Method of Treating Psoriatic Arthritis with Anti-IL23 Specific Antibody |
WO2022251623A1 (fr) | 2021-05-28 | 2022-12-01 | Eli Lilly And Company | Régulation d'anticorps anti-il-23p19 de gènes impliqués dans la rectocolite hémorragique |
AU2022306973A1 (en) | 2021-07-09 | 2024-02-22 | Janssen Biotech, Inc. | Manufacturing methods for producing anti-il12/il23 antibody compositions |
CN115785267B (zh) * | 2021-09-10 | 2023-12-15 | 三优生物医药(上海)有限公司 | 一种靶向IL-23p19的抗体或其抗原结合片段及其应用 |
WO2023051798A1 (fr) * | 2021-09-30 | 2023-04-06 | 江苏恒瑞医药股份有限公司 | Protéine de fusion d'anticorps anti-il23 et ses utilisations |
WO2023056417A1 (fr) | 2021-09-30 | 2023-04-06 | Eli Lilly And Company | Régulation d'anticorps anti-il-23p19 de gènes impliqués dans l'urgence intestinale dans la colite ulcéreuse |
EP4423126A1 (fr) | 2021-10-29 | 2024-09-04 | Janssen Biotech, Inc. | Méthodes de traitement de la maladie de crohn avec un anticorps spécifique anti-il23 |
CA3238377A1 (fr) | 2021-11-15 | 2023-05-19 | Janssen Biotech, Inc. | Methodes de traitement de la maladie de crohn au moyen d'un anticorps specifique anti-il23 |
US20230159633A1 (en) | 2021-11-23 | 2023-05-25 | Janssen Biotech, Inc. | Method of Treating Ulcerative Colitis with Anti-IL23 Specific Antibody |
AU2022414309A1 (en) * | 2021-12-17 | 2024-08-01 | Janssen Biotech, Inc. | Il-23 specific antibodies for the treatment of systemic sclerosis |
US20230312703A1 (en) | 2022-03-30 | 2023-10-05 | Janssen Biotech, Inc. | Method of Treating Psoriasis with IL-23 Specific Antibody |
US20230374122A1 (en) | 2022-05-18 | 2023-11-23 | Janssen Biotech, Inc. | Method for Evaluating and Treating Psoriatic Arthritis with IL23 Antibody |
WO2024073588A1 (fr) * | 2022-09-28 | 2024-04-04 | Board Of Regents, The University Of Texas System | Administration de poudre sèche respiratoire |
WO2024077113A1 (fr) | 2022-10-06 | 2024-04-11 | Eli Lilly And Company | Méthodes de traitement de la fatigue liée à la colite ulcéreuse |
US20240199734A1 (en) | 2022-11-22 | 2024-06-20 | Janssen Biotech, Inc. | Method of Treating Ulcerative Colitis with Anti-IL23 Specific Antibody |
WO2024178157A1 (fr) | 2023-02-22 | 2024-08-29 | Eli Lilly And Company | Régulation de gènes dans la colite ulcéreuse et leurs utilisations |
Family Cites Families (166)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
US4309989A (en) | 1976-02-09 | 1982-01-12 | The Curators Of The University Of Missouri | Topical application of medication by ultrasound with coupling agent |
FR2374910A1 (fr) | 1976-10-23 | 1978-07-21 | Choay Sa | Preparation a base d'heparine, comprenant des liposomes, procede pour l'obtenir et medicaments contenant de telles preparations |
FR2413974A1 (fr) | 1978-01-06 | 1979-08-03 | David Bernard | Sechoir pour feuilles imprimees par serigraphie |
US5179017A (en) | 1980-02-25 | 1993-01-12 | The Trustees Of Columbia University In The City Of New York | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
US4634665A (en) | 1980-02-25 | 1987-01-06 | The Trustees Of Columbia University In The City Of New York | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
US4399216A (en) | 1980-02-25 | 1983-08-16 | The Trustees Of Columbia University | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
GB2097032B (en) | 1981-04-22 | 1984-09-19 | Teron International Urban Dev | A combined ceiling air and services distribution system mechanical chasse and structural roof member |
US4656134A (en) | 1982-01-11 | 1987-04-07 | Board Of Trustees Of Leland Stanford Jr. University | Gene amplification in eukaryotic cells |
US5149636A (en) | 1982-03-15 | 1992-09-22 | Trustees Of Columbia University In The City Of New York | Method for introducing cloned, amplifiable genes into eucaryotic cells and for producing proteinaceous products |
US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
US4818542A (en) | 1983-11-14 | 1989-04-04 | The University Of Kentucky Research Foundation | Porous microspheres for drug delivery and methods for making same |
US5168062A (en) | 1985-01-30 | 1992-12-01 | University Of Iowa Research Foundation | Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence |
US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
US4965188A (en) | 1986-08-22 | 1990-10-23 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme |
US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
US6492107B1 (en) | 1986-11-20 | 2002-12-10 | Stuart Kauffman | Process for obtaining DNA, RNA, peptides, polypeptides, or protein, by recombinant DNA technique |
DE3590766T (fr) | 1985-03-30 | 1987-04-23 | ||
SE448277B (sv) | 1985-04-12 | 1987-02-09 | Draco Ab | Indikeringsanordning vid en doseringsanordning for lekemedel |
US4766067A (en) | 1985-05-31 | 1988-08-23 | President And Fellows Of Harvard College | Gene amplification |
US4870163A (en) | 1985-08-29 | 1989-09-26 | New York Blood Center, Inc. | Preparation of pure human tumor necrosis factor and hybridomas producing monoclonal antibodies to human tumor necrosis factor |
US4676980A (en) | 1985-09-23 | 1987-06-30 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Target specific cross-linked heteroantibodies |
US5576195A (en) | 1985-11-01 | 1996-11-19 | Xoma Corporation | Vectors with pectate lyase signal sequence |
US5618920A (en) | 1985-11-01 | 1997-04-08 | Xoma Corporation | Modular assembly of antibody genes, antibodies prepared thereby and use |
DE3600905A1 (de) | 1986-01-15 | 1987-07-16 | Ant Nachrichtentech | Verfahren zum dekodieren von binaersignalen sowie viterbi-dekoder und anwendungen |
GB8601597D0 (en) | 1986-01-23 | 1986-02-26 | Wilson R H | Nucleotide sequences |
US4800159A (en) | 1986-02-07 | 1989-01-24 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences |
SE453566B (sv) | 1986-03-07 | 1988-02-15 | Draco Ab | Anordning vid pulverinhalatorer |
US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
US4767402A (en) | 1986-07-08 | 1988-08-30 | Massachusetts Institute Of Technology | Ultrasound enhancement of transdermal drug delivery |
AU610083B2 (en) | 1986-08-18 | 1991-05-16 | Clinical Technologies Associates, Inc. | Delivery systems for pharmacological agents |
US4889818A (en) | 1986-08-22 | 1989-12-26 | Cetus Corporation | Purified thermostable enzyme |
US5260203A (en) | 1986-09-02 | 1993-11-09 | Enzon, Inc. | Single polypeptide chain binding molecules |
US4704692A (en) | 1986-09-02 | 1987-11-03 | Ladner Robert C | Computer based system and method for determining and displaying possible chemical structures for converting double- or multiple-chain polypeptides to single-chain polypeptides |
US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
DE3631229A1 (de) | 1986-09-13 | 1988-03-24 | Basf Ag | Monoklonale antikoerper gegen humanen tumornekrosefaktor (tnf) und deren verwendung |
US4795699A (en) | 1987-01-14 | 1989-01-03 | President And Fellows Of Harvard College | T7 DNA polymerase |
US4921794A (en) | 1987-01-14 | 1990-05-01 | President And Fellows Of Harvard College | T7 DNA polymerase |
EP0832981A1 (fr) | 1987-02-17 | 1998-04-01 | Pharming B.V. | Séquences d'ADN pour diriger des protéines vers les glandes mammaires, afin d'être secrétées efficacement |
US5075236A (en) | 1987-04-24 | 1991-12-24 | Teijin Limited | Method of detecting kawasaki disease using anti-tumor necrosis antibody |
US4873316A (en) | 1987-06-23 | 1989-10-10 | Biogen, Inc. | Isolation of exogenous recombinant proteins from the milk of transgenic mammals |
US4939666A (en) | 1987-09-02 | 1990-07-03 | Genex Corporation | Incremental macromolecule construction methods |
US6010902A (en) | 1988-04-04 | 2000-01-04 | Bristol-Meyers Squibb Company | Antibody heteroconjugates and bispecific antibodies for use in regulation of lymphocyte activity |
US4956288A (en) | 1988-04-22 | 1990-09-11 | Biogen, Inc. | Method for producing cells containing stably integrated foreign DNA at a high copy number, the cells produced by this method, and the use of these cells to produce the polypeptides coded for by the foreign DNA |
US5130238A (en) | 1988-06-24 | 1992-07-14 | Cangene Corporation | Enhanced nucleic acid amplification process |
US5601819A (en) | 1988-08-11 | 1997-02-11 | The General Hospital Corporation | Bispecific antibodies for selective immune regulation and for selective immune cell binding |
US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
US5091310A (en) | 1988-09-23 | 1992-02-25 | Cetus Corporation | Structure-independent dna amplification by the polymerase chain reaction |
US5142033A (en) | 1988-09-23 | 1992-08-25 | Hoffmann-La Roche Inc. | Structure-independent DNA amplification by the polymerase chain reaction |
US5066584A (en) | 1988-09-23 | 1991-11-19 | Cetus Corporation | Methods for generating single stranded dna by the polymerase chain reaction |
US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
US4994370A (en) | 1989-01-03 | 1991-02-19 | The United States Of America As Represented By The Department Of Health And Human Services | DNA amplification technique |
US5225538A (en) | 1989-02-23 | 1993-07-06 | Genentech, Inc. | Lymphocyte homing receptor/immunoglobulin fusion proteins |
US5116964A (en) | 1989-02-23 | 1992-05-26 | Genentech, Inc. | Hybrid immunoglobulins |
US5266491A (en) | 1989-03-14 | 1993-11-30 | Mochida Pharmaceutical Co., Ltd. | DNA fragment and expression plasmid containing the DNA fragment |
DE3909708A1 (de) | 1989-03-23 | 1990-09-27 | Boehringer Mannheim Gmbh | Verfahren zur herstellung bispezifischer antikoerper |
CA2016841C (fr) | 1989-05-16 | 1999-09-21 | William D. Huse | Methode de production de polymeres ayant une activite choisie |
CA2016842A1 (fr) | 1989-05-16 | 1990-11-16 | Richard A. Lerner | Methode pour puiser dans le repertoire immunologique |
CA2057923A1 (fr) | 1989-05-16 | 1990-11-17 | William D. Huse | Co-expression de recepteurs heteromeriques |
DE69029036T2 (de) | 1989-06-29 | 1997-05-22 | Medarex Inc | Bispezifische reagenzien für die aids-therapie |
EP0486526B2 (fr) | 1989-08-07 | 2001-03-07 | Peptech Limited | Ligands de liaison du facteur de necrose de tumeurs |
DK0494955T3 (da) | 1989-10-05 | 1998-10-26 | Optein Inc | Cellefri syntese og isolering af hidtil ukendte gener og polypeptider |
US5859205A (en) * | 1989-12-21 | 1999-01-12 | Celltech Limited | Humanised antibodies |
US5580575A (en) | 1989-12-22 | 1996-12-03 | Imarx Pharmaceutical Corp. | Therapeutic drug delivery systems |
JP3112463B2 (ja) * | 1990-03-27 | 2000-11-27 | 雪印乳業株式会社 | モノクローナル抗体の作製方法 |
TW212184B (fr) | 1990-04-02 | 1993-09-01 | Takeda Pharm Industry Co Ltd | |
US5427908A (en) | 1990-05-01 | 1995-06-27 | Affymax Technologies N.V. | Recombinant library screening methods |
ATE160818T1 (de) | 1990-06-01 | 1997-12-15 | Chiron Corp | Zusammensetzungen und verfahren zur identifizierung von molekülen mit biologischer wirksamkeit |
US5723286A (en) | 1990-06-20 | 1998-03-03 | Affymax Technologies N.V. | Peptide library and screening systems |
CA2086417C (fr) | 1990-06-29 | 1999-07-06 | Biosource Technologies, Inc. | Production de melanine par des microorganismes transformes |
US5580734A (en) | 1990-07-13 | 1996-12-03 | Transkaryotic Therapies, Inc. | Method of producing a physical map contigous DNA sequences |
WO1992005258A1 (fr) | 1990-09-20 | 1992-04-02 | La Trobe University | Gene encodant une enzyme de l'orge |
GB9022648D0 (en) | 1990-10-18 | 1990-11-28 | Charing Cross Sunley Research | Polypeptide and its use |
ATE160379T1 (de) | 1990-10-29 | 1997-12-15 | Chiron Corp | Bispezifische antikörper, verfahren zu ihrer herstellung und deren verwendungen |
DK0564531T3 (da) | 1990-12-03 | 1998-09-28 | Genentech Inc | Berigelsesfremgangsmåde for variantproteiner med ændrede bindingsegenskaber |
US5582996A (en) | 1990-12-04 | 1996-12-10 | The Wistar Institute Of Anatomy & Biology | Bifunctional antibodies and method of preparing same |
CA2104698A1 (fr) | 1991-02-21 | 1992-08-22 | John J. Toole | Aptameres specifiques de biomolecules et methodes de production |
US5404871A (en) | 1991-03-05 | 1995-04-11 | Aradigm | Delivery of aerosol medications for inspiration |
GEP20033082B (en) | 1991-03-15 | 2003-10-27 | Amgen Inc | Pegylation of Polypeptides |
DE4118120A1 (de) | 1991-06-03 | 1992-12-10 | Behringwerke Ag | Tetravalente bispezifische rezeptoren, ihre herstellung und verwendung |
US5637481A (en) | 1993-02-01 | 1997-06-10 | Bristol-Myers Squibb Company | Expression vectors encoding bispecific fusion proteins and methods of producing biologically active bispecific fusion proteins in a mammalian cell |
DE69233690T2 (de) | 1991-07-02 | 2008-01-24 | Nektar Therapeutics, San Carlos | Abgabevorrichtung für nebelförmige Medikamente |
US5270170A (en) | 1991-10-16 | 1993-12-14 | Affymax Technologies N.V. | Peptide library and screening method |
WO1993008829A1 (fr) | 1991-11-04 | 1993-05-13 | The Regents Of The University Of California | Compositions induisant la destruction de cellules infectees par l'hiv |
US5641670A (en) | 1991-11-05 | 1997-06-24 | Transkaryotic Therapies, Inc. | Protein production and protein delivery |
US5733761A (en) | 1991-11-05 | 1998-03-31 | Transkaryotic Therapies, Inc. | Protein production and protein delivery |
US5932448A (en) | 1991-11-29 | 1999-08-03 | Protein Design Labs., Inc. | Bispecific antibody heterodimers |
PT1024191E (pt) | 1991-12-02 | 2008-12-22 | Medical Res Council | Produção de auto-anticorpos a partir de reportórios de segmentos de anticorpo e exibidos em fagos |
CA2103887C (fr) | 1991-12-13 | 2005-08-30 | Gary M. Studnicka | Methodes et materiaux pour la preparation de domaines variables d'anticorps modifies et leurs utilisations therapeutiques |
DE4207475A1 (de) | 1992-03-10 | 1993-09-16 | Goldwell Ag | Mittel zum blondieren von menschlichen haaren und verfahren zu dessen herstellung |
US5447851B1 (en) | 1992-04-02 | 1999-07-06 | Univ Texas System Board Of | Dna encoding a chimeric polypeptide comprising the extracellular domain of tnf receptor fused to igg vectors and host cells |
AU4829593A (en) | 1992-09-23 | 1994-04-12 | Fisons Plc | Inhalation device |
AU5322494A (en) | 1992-10-02 | 1994-04-26 | Trustees Of Dartmouth College | Bispecific reagents for redirected targeting of low density lipoprotein |
PL172758B1 (pl) | 1992-10-19 | 1997-11-28 | Dura Pharma Inc | Inhalator do proszków suchych PL PL PL PL PL PL PL |
US5643252A (en) | 1992-10-28 | 1997-07-01 | Venisect, Inc. | Laser perforator |
AU5670194A (en) | 1992-11-20 | 1994-06-22 | Enzon, Inc. | Linker for linked fusion polypeptides |
US5849695A (en) | 1993-01-13 | 1998-12-15 | The Regents Of The University Of California | Parathyroid hormone analogues useful for treatment of osteoporosis and disorders of calcium meatabolism in mammals |
DK0680451T3 (da) | 1993-01-19 | 1999-07-19 | Glaxo Group Ltd | Aerosoldispenser samt fremgangsmåde ved dens fremstilling |
WO1994018317A1 (fr) | 1993-02-12 | 1994-08-18 | The Board Of Trustees Of The Leland Stanford Junior University | Transcription regulee de genes cibles et d'autres evenements biologiques |
US5514670A (en) | 1993-08-13 | 1996-05-07 | Pharmos Corporation | Submicron emulsions for delivery of peptides |
DE4337197C1 (de) | 1993-10-30 | 1994-08-25 | Biotest Pharma Gmbh | Verfahren zur selektiven Herstellung von Hybridomazellinien, die monoklonale Antikörper mit hoher Zytotoxizität gegen humanes CD16-Antigen produzieren, sowie Herstellung bispezifischer monoklonaler Antikörper unter Verwendung derartiger monoklonaler Antikörper und des CD30-HRS-3-Antikörpers zur Therapie menschlicher Tumore |
US5814599A (en) | 1995-08-04 | 1998-09-29 | Massachusetts Insitiute Of Technology | Transdermal delivery of encapsulated drugs |
US5827690A (en) | 1993-12-20 | 1998-10-27 | Genzyme Transgenics Corporatiion | Transgenic production of antibodies in milk |
WO1995024220A1 (fr) | 1994-03-07 | 1995-09-14 | Medarex, Inc. | Molecules bispecifiques se pretant a des utilisations cliniques |
US5763733A (en) | 1994-10-13 | 1998-06-09 | Enzon, Inc. | Antigen-binding fusion proteins |
US5549551A (en) | 1994-12-22 | 1996-08-27 | Advanced Cardiovascular Systems, Inc. | Adjustable length balloon catheter |
US5731168A (en) | 1995-03-01 | 1998-03-24 | Genentech, Inc. | Method for making heteromultimeric polypeptides |
US6037453A (en) | 1995-03-15 | 2000-03-14 | Genentech, Inc. | Immunoglobulin variants |
US5656730A (en) | 1995-04-07 | 1997-08-12 | Enzon, Inc. | Stabilized monomeric protein compositions |
US6019968A (en) | 1995-04-14 | 2000-02-01 | Inhale Therapeutic Systems, Inc. | Dispersible antibody compositions and methods for their preparation and use |
US5730723A (en) | 1995-10-10 | 1998-03-24 | Visionary Medical Products Corporation, Inc. | Gas pressured needle-less injection device and method |
GB9526100D0 (en) | 1995-12-20 | 1996-02-21 | Intersurgical Ltd | Nebulizer |
JP2000503565A (ja) | 1996-01-03 | 2000-03-28 | グラクソ、グループ、リミテッド | 吸入装置 |
US5714352A (en) | 1996-03-20 | 1998-02-03 | Xenotech Incorporated | Directed switch-mediated DNA recombination |
ES2169299T3 (es) | 1996-09-03 | 2002-07-01 | Gsf Forschungszentrum Umwelt | Procedimiento para la destruccion de celulas tumorales contaminantes en transplantes de celulas madre utilizando anticuerpos especificos. |
US5879681A (en) | 1997-02-07 | 1999-03-09 | Emisphere Technolgies Inc. | Compounds and compositions for delivering active agents |
US5921447A (en) | 1997-02-13 | 1999-07-13 | Glaxo Wellcome Inc. | Flow-through metered aerosol dispensing apparatus and method of use thereof |
IL120943A (en) | 1997-05-29 | 2004-03-28 | Univ Ben Gurion | A system for administering drugs through the skin |
CO4810232A1 (es) | 1997-07-25 | 1999-06-30 | Schering Corp | Citoquinas de mamiferos y sus secuencias codificadoras |
US6060284A (en) | 1997-07-25 | 2000-05-09 | Schering Corporation | DNA encoding interleukin-B30 |
ATE239447T1 (de) | 1997-09-29 | 2003-05-15 | Inhale Therapeutic Syst | In verneblern verwendbare, stabilisierte zubereitungen |
AU2661199A (en) | 1998-02-06 | 1999-08-23 | Schering Corporation | Mammalian receptor proteins; related reagents and methods |
ATE474849T1 (de) | 1998-04-14 | 2010-08-15 | Chugai Pharmaceutical Co Ltd | Neues cytokinartiges protein |
DK2180007T4 (da) | 1998-04-20 | 2017-11-27 | Roche Glycart Ag | Glycosyleringsteknik for antistoffer til forbedring af antistofafhængig cellecytotoxicitet |
WO2000009552A1 (fr) | 1998-08-14 | 2000-02-24 | Genetics Institute, Inc. | Proteines secretees et polynucleotides les codant |
KR20060067983A (ko) | 1999-01-15 | 2006-06-20 | 제넨테크, 인크. | 효과기 기능이 변화된 폴리펩티드 변이체 |
AR022890A1 (es) | 1999-03-11 | 2002-09-04 | Schering Corp | Citoquinas mamiferas; reactivos relacionados y metodos |
US6800460B1 (en) | 1999-03-11 | 2004-10-05 | Schering Corporation | Mammalian cytokine complexes |
EP1179066A2 (fr) | 1999-05-19 | 2002-02-13 | Incyte Genomics, Inc. | Molecules de signalisation extracellulaires |
US6309663B1 (en) | 1999-08-17 | 2001-10-30 | Lipocine Inc. | Triglyceride-free compositions and methods for enhanced absorption of hydrophilic therapeutic agents |
US7090847B1 (en) | 1999-09-09 | 2006-08-15 | Schering Corporation | Mammalian cytokines; related reagents and methods |
DE60038304T3 (de) | 1999-09-09 | 2017-04-06 | Merck Sharp & Dohme Corp. | Interleukin-12 p40 und interleukin-b30. kombinationen davon. antikörper. verwendungen in pharmazeutische zusammensetzungen |
GB0001448D0 (en) | 2000-01-21 | 2000-03-08 | Novartis Ag | Organic compounds |
US20020090672A1 (en) | 2000-01-31 | 2002-07-11 | Rosen Craig A. | Nucleic acids, proteins, and antibodies |
US7422743B2 (en) | 2000-05-10 | 2008-09-09 | Schering Corporation | Mammalian receptor protein DCRS5;methods of treatment |
ES2307618T3 (es) | 2000-05-10 | 2008-12-01 | Schering Corporation | Proteinas subunidades de receptores de cotocinas de mamiferos, reactivos y metodos relacionados. |
EP1383800A4 (fr) | 2001-04-02 | 2004-09-22 | Idec Pharma Corp | Anticorps recombinants co-exprimes avec gntiii |
ITPD20010108A1 (it) | 2001-05-08 | 2002-11-08 | Fidia Advanced Biopolymers Srl | Biomateriali polimerici elettricamente conduttori, loro processo di preparazione ed impiego nel settore biomedico sanitario. |
NZ592087A (en) | 2001-08-03 | 2012-11-30 | Roche Glycart Ag | Antibody glycosylation variants having increased antibody-dependent cellular cytotoxicity |
CA2501786C (fr) * | 2002-10-30 | 2015-02-17 | Genentech, Inc. | Inhibition de la production d'il-17 |
WO2004050683A2 (fr) * | 2002-12-02 | 2004-06-17 | Abgenix, Inc. | Anticorps agissant sur le facteur de necrose des tumeurs (tnf) et leurs utilisation |
ES2367302T3 (es) | 2002-12-23 | 2011-11-02 | Schering Corporation | Usos de la citoquina il-23 de mamífero; reactivos relacionados. |
US20040219150A1 (en) | 2003-02-06 | 2004-11-04 | Cua Daniel J. | Uses of mammalian cytokine; related reagents |
SI2236154T1 (en) * | 2003-02-10 | 2018-08-31 | Biogen Ma Inc. | THE FORM OF IMUNOGLOBULIN AND THE METHOD OF ITS PREPARATION |
ES2330220T3 (es) * | 2003-03-10 | 2009-12-07 | Schering Corporation | Usos de antagonistas de il-23; reactivos relacionados. |
US20040185506A1 (en) * | 2003-03-21 | 2004-09-23 | Heavner George A. | Epitope mapping using nuclear magnetic resonance |
CN101052726A (zh) | 2003-05-09 | 2007-10-10 | 森托科尔公司 | IL-23p40特异性免疫球蛋白衍生蛋白、组合物、方法和用途 |
EP1644416A4 (fr) | 2003-06-30 | 2007-08-29 | Centocor Inc | Proteines derivees de l'immunoglobuline anti-cible et genetiquement modifiees, compositions, procedes et utilisations |
DE10355251A1 (de) * | 2003-11-26 | 2005-06-23 | Merck Patent Gmbh | Pharmazeutische Zubereitung enthaltend einen Antikörper gegen den EGF-Rezeptor |
ES2541489T3 (es) * | 2004-02-06 | 2015-07-21 | Morphosys Ag | Anticuerpos humanos anti-CD38 y usos para ellos |
BRPI0507794A (pt) | 2004-02-17 | 2007-07-17 | Schering Corp | métodos de modular a atividade de il-23, reagentes relacionados |
WO2005108616A1 (fr) | 2004-05-03 | 2005-11-17 | Schering Corporation | Utilisation de l'expression d'il-17 pour predire une inflammation cutanee et methodes de traitement |
WO2005108425A1 (fr) * | 2004-05-10 | 2005-11-17 | Cytos Biotechnology Ag | Reseau antigene il-23 p19 et utilisations |
AR051444A1 (es) | 2004-09-24 | 2007-01-17 | Centocor Inc | Proteinas derivadas de inmunoglobulina especifica de il-23p40, composiciones, epitopos, metodos y usos |
GT200600031A (es) * | 2005-01-28 | 2006-08-29 | Formulacion anticuerpo anti a beta | |
US20060194981A1 (en) * | 2005-02-26 | 2006-08-31 | Jass Paul A | Process for preparation of probucol derivatives |
CA2613818C (fr) * | 2005-06-30 | 2013-08-27 | Centocor, Inc. | Anticorps anti-il-23, compositions, methodes et utilisations |
PL1937721T3 (pl) | 2005-08-25 | 2010-12-31 | Lilly Co Eli | Przeciwciała anty-IL23 |
SG165322A1 (en) | 2005-08-31 | 2010-10-28 | Schering Corp | Engineered anti-il-23 antibodies |
EA035459B1 (ru) | 2005-12-29 | 2020-06-19 | Сентокор, Инк. | Антитело против il-23p19 |
JP5470817B2 (ja) | 2008-03-10 | 2014-04-16 | 日産自動車株式会社 | 電池用電極およびこれを用いた電池、並びにその製造方法 |
JP6136279B2 (ja) | 2013-01-15 | 2017-05-31 | 株式会社ジェイテクト | 転がり軸受装置 |
TWI503850B (zh) | 2013-03-22 | 2015-10-11 | Polytronics Technology Corp | 過電流保護元件 |
TWI510996B (zh) | 2013-10-03 | 2015-12-01 | Acer Inc | 控制觸控面板的方法以及使用該方法的可攜式電腦 |
US9353645B1 (en) | 2015-02-16 | 2016-05-31 | Borgwarner Inc. | Vane ring thermal strain relief cuts |
US9816280B1 (en) | 2016-11-02 | 2017-11-14 | Matthew Reitnauer | Portable floor |
-
2006
- 2006-12-28 EA EA201301072A patent/EA035459B1/ru unknown
- 2006-12-28 MY MYPI2011001645A patent/MY162559A/en unknown
- 2006-12-28 LT LTEP12174197.9T patent/LT2548577T/lt unknown
- 2006-12-28 CN CN201210297501.1A patent/CN102887954B/zh active Active
- 2006-12-28 MY MYPI20082401A patent/MY163032A/en unknown
- 2006-12-28 EP EP12174197.9A patent/EP2548577B1/fr active Active
- 2006-12-28 CA CA2635692A patent/CA2635692C/fr active Active
- 2006-12-28 ES ES12174197.9T patent/ES2622602T3/es active Active
- 2006-12-28 CN CN2006800535467A patent/CN101389351B/zh active Active
- 2006-12-28 BR BRPI0620946A patent/BRPI0620946B8/pt active IP Right Grant
- 2006-12-28 DK DK17156111.1T patent/DK3219328T3/da active
- 2006-12-28 EP EP20180279.0A patent/EP3760230A1/fr active Pending
- 2006-12-28 PL PL12174197T patent/PL2548577T3/pl unknown
- 2006-12-28 DK DK12174197.9T patent/DK2548577T3/en active
- 2006-12-28 ES ES17156111T patent/ES2807928T3/es active Active
- 2006-12-28 LT LTEP17156111.1T patent/LT3219328T/lt unknown
- 2006-12-28 AU AU2006330411A patent/AU2006330411B2/en active Active
- 2006-12-28 US US11/617,503 patent/US7935344B2/en active Active
- 2006-12-28 PT PT121741979T patent/PT2548577T/pt unknown
- 2006-12-28 KR KR1020087018522A patent/KR101210395B1/ko active IP Right Grant
- 2006-12-28 HU HUE12174197A patent/HUE034269T2/en unknown
- 2006-12-28 PT PT171561111T patent/PT3219328T/pt unknown
- 2006-12-28 WO PCT/US2006/062674 patent/WO2007076524A2/fr active Application Filing
- 2006-12-28 JP JP2008548853A patent/JP5193881B2/ja active Active
- 2006-12-28 MX MX2008008621A patent/MX2008008621A/es active IP Right Grant
- 2006-12-28 HU HUE17156111A patent/HUE049832T2/hu unknown
- 2006-12-28 EA EA200870129A patent/EA019476B9/ru active Protection Beyond IP Right Term
- 2006-12-28 SI SI200632385T patent/SI3219328T1/sl unknown
- 2006-12-28 EP EP06846836.2A patent/EP1971366B1/fr active Active
- 2006-12-28 UA UAA200809846A patent/UA101301C2/ru unknown
- 2006-12-28 SI SI200632156A patent/SI2548577T1/sl unknown
- 2006-12-28 SG SG10201505755YA patent/SG10201505755YA/en unknown
- 2006-12-28 NZ NZ569546A patent/NZ569546A/en unknown
- 2006-12-28 NO NO20240354A patent/NO20240354A1/no unknown
- 2006-12-28 PT PT68468362T patent/PT1971366E/pt unknown
- 2006-12-28 PL PL17156111T patent/PL3219328T3/pl unknown
- 2006-12-28 EP EP17156111.1A patent/EP3219328B1/fr not_active Revoked
- 2006-12-28 RS RS20140565A patent/RS53685B1/en unknown
- 2006-12-28 ES ES06846836.2T patent/ES2517420T3/es active Active
- 2006-12-28 RS RS20200911A patent/RS60616B1/sr unknown
- 2006-12-28 SI SI200631828T patent/SI1971366T1/sl unknown
- 2006-12-28 PL PL06846836T patent/PL1971366T3/pl unknown
- 2006-12-28 DK DK06846836.2T patent/DK1971366T3/da active
- 2006-12-28 RS RS20170468A patent/RS55963B1/sr unknown
-
2008
- 2008-06-26 IL IL192458A patent/IL192458A/en active IP Right Grant
- 2008-06-27 SV SV2008002972A patent/SV2008002972A/es unknown
- 2008-06-27 NI NI200800193A patent/NI200800193A/es unknown
- 2008-06-27 HN HN2008000988A patent/HN2008000988A/es unknown
- 2008-06-30 MX MX2012006997A patent/MX342595B/es unknown
- 2008-06-30 EC EC2008008591A patent/ECSP088591A/es unknown
- 2008-07-01 GT GT200800132A patent/GT200800132A/es unknown
- 2008-07-23 NO NO20083266A patent/NO343345B1/no active Protection Beyond IP Right Term
- 2008-07-28 ZA ZA200806556A patent/ZA200806556B/xx unknown
- 2008-07-29 CR CR10181A patent/CR10181A/es not_active Application Discontinuation
-
2009
- 2009-03-18 HK HK09102604.5A patent/HK1124548A1/xx unknown
-
2010
- 2010-08-12 US US12/855,354 patent/US7993645B2/en active Active
-
2011
- 2011-04-04 US US13/079,457 patent/US8106177B2/en active Active
- 2011-06-30 US US13/173,090 patent/US8221760B2/en active Active
-
2012
- 2012-05-20 IL IL219890A patent/IL219890A/en active IP Right Grant
- 2012-06-15 US US13/524,122 patent/US9353181B2/en active Active
-
2014
- 2014-10-14 HR HRP20140982TT patent/HRP20140982T1/hr unknown
- 2014-10-29 CY CY20141100889T patent/CY1115935T1/el unknown
- 2014-12-24 IL IL236427A patent/IL236427A/en active IP Right Grant
-
2016
- 2016-04-29 US US15/142,765 patent/US9783607B2/en active Active
- 2016-11-13 IL IL248917A patent/IL248917A0/en unknown
-
2017
- 2017-05-04 HR HRP20170675TT patent/HRP20170675T1/hr unknown
- 2017-05-04 CY CY20171100485T patent/CY1118880T1/el unknown
- 2017-09-01 US US15/694,107 patent/US10030070B2/en active Active
-
2018
- 2018-04-16 IL IL258718A patent/IL258718A/en unknown
- 2018-04-25 LU LU00071C patent/LUC00071I2/fr unknown
- 2018-04-26 NL NL300935C patent/NL300935I2/nl unknown
- 2018-05-02 HU HUS1800021C patent/HUS1800021I1/hu unknown
- 2018-05-07 CY CY2018013C patent/CY2018013I2/el unknown
- 2018-05-08 LT LTPA2018010C patent/LTC1971366I2/lt unknown
- 2018-06-20 US US16/013,141 patent/US10954297B2/en active Active
-
2019
- 2019-01-04 NO NO20190011A patent/NO344118B1/no unknown
- 2019-07-10 NO NO2019029C patent/NO2019029I1/no unknown
- 2019-08-16 NO NO20190992A patent/NO347867B1/no unknown
-
2020
- 2020-08-03 HR HRP20201215TT patent/HRP20201215T1/hr unknown
- 2020-08-31 CY CY20201100813T patent/CY1123400T1/el unknown
-
2021
- 2021-02-22 US US17/181,778 patent/US20210188966A1/en active Granted
-
2024
- 2024-02-16 US US18/444,595 patent/US20240199733A1/en active Pending
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
LUC00071I2 (fr) | ||
BE2012C042I2 (fr) | ||
BRPI0601358B8 (pt) | Aplicador de clipe cirúrgico | |
BRPI0601402B8 (pt) | Aplicador de grampos cirúrgicos | |
JP2006330895A5 (fr) | ||
BR122017004707A2 (fr) | ||
BRPI0609157A8 (fr) | ||
BRPI0608519A2 (fr) | ||
BR122020005056A2 (fr) | ||
AP2140A (fr) | ||
BR122016029989A2 (fr) | ||
BRPI0604219A (fr) | ||
BRPI0618215B8 (fr) | ||
JP2007000947A5 (fr) | ||
BY2237U (fr) | ||
FR2881471B1 (fr) | ||
CN105122969C (fr) | ||
CN300726696S (zh) | 调料瓶套装(c) | |
CN300726592S (zh) | 碗用具(双壁式4) | |
CN300725991S (zh) | 鞋帮 | |
CN300725996S (zh) | 鞋帮 | |
CN300725997S (zh) | 鞋帮 | |
CN300725992S (zh) | 鞋底 | |
CN300725995S (zh) | 鞋帮 | |
CN300725993S (zh) | 鞋帮 |