NO20083266L - Humane anti-IL-23-antistoffer, sammensetninger, fremgangsmater og anvendelser - Google Patents

Humane anti-IL-23-antistoffer, sammensetninger, fremgangsmater og anvendelser

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Publication number
NO20083266L
NO20083266L NO20083266A NO20083266A NO20083266L NO 20083266 L NO20083266 L NO 20083266L NO 20083266 A NO20083266 A NO 20083266A NO 20083266 A NO20083266 A NO 20083266A NO 20083266 L NO20083266 L NO 20083266L
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NO
Norway
Prior art keywords
methods
applications
human anti
compositions
antibodies
Prior art date
Application number
NO20083266A
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English (en)
Other versions
NO343345B1 (no
Inventor
Mark Cunningham
Raymond Sweet
Jacqueline Benson
Jill Carton
Yevgeniya I Orlovsky
Robert Rauchenberger
Original Assignee
Centocor Inc
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Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38218878&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20083266(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Centocor Inc filed Critical Centocor Inc
Publication of NO20083266L publication Critical patent/NO20083266L/no
Publication of NO343345B1 publication Critical patent/NO343345B1/no

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183Amino acids, e.g. glycine, EDTA or aspartame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K9/08Solutions
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    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61P17/06Antipsoriatics
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    • A61P17/08Antiseborrheics
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10Cells modified by introduction of foreign genetic material
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • G01N33/567Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds utilising isolate of tissue or organ as binding agent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
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    • C07ORGANIC CHEMISTRY
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    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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    • C07ORGANIC CHEMISTRY
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    • C07K2317/00Immunoglobulins specific features
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    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
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    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
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    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
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    • C07ORGANIC CHEMISTRY
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    • C07K2319/00Fusion polypeptide
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

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Abstract

Sammendrag Et humant anti-IL-23p19 antistoff, inkludert isolerte nukleinsyrer som koder for minst et anti-IL-23p19 antistoff, vektorer, vertsceller, og fremgangsmåter for å lage og bruke derav har anvendelser i diagnostisk og/eller terapeutiske sammensetninger, fremgangsmåter og anordninger.
NO20083266A 2005-12-29 2008-07-23 Humane anti-IL-23-antistoffer, sammensetninger, fremgangsmåter og anvendelser av slike NO343345B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US75488905P 2005-12-29 2005-12-29
PCT/US2006/062674 WO2007076524A2 (en) 2005-12-29 2006-12-28 Human anti-il-23 antibodies, compositions, methods and uses

Publications (2)

Publication Number Publication Date
NO20083266L true NO20083266L (no) 2008-09-29
NO343345B1 NO343345B1 (no) 2019-02-04

Family

ID=38218878

Family Applications (4)

Application Number Title Priority Date Filing Date
NO20083266A NO343345B1 (no) 2005-12-29 2008-07-23 Humane anti-IL-23-antistoffer, sammensetninger, fremgangsmåter og anvendelser av slike
NO20190011A NO344118B1 (no) 2005-12-29 2019-01-04 Humane anti-IL-23-antistoffer, sammensetninger, in vitro fremgangsmåter og anvendelser av slike, samt nukleinsyremolekyler, vektorer og vertsceller, og medisinsk anordning og artikkel.
NO2019029C NO2019029I1 (no) 2005-12-29 2019-07-10 Guselkumab, se følgebrevet for nærmere forklaring
NO20190992A NO347867B1 (no) 2005-12-29 2019-08-16 Isolerte IL-23p19 antistoffer, nukleinsyremolekyler, vektorer og vertsceller, samt sammensetninger, fremgangsmåter og en medisinsk anordning, og en artikkel.

Family Applications After (3)

Application Number Title Priority Date Filing Date
NO20190011A NO344118B1 (no) 2005-12-29 2019-01-04 Humane anti-IL-23-antistoffer, sammensetninger, in vitro fremgangsmåter og anvendelser av slike, samt nukleinsyremolekyler, vektorer og vertsceller, og medisinsk anordning og artikkel.
NO2019029C NO2019029I1 (no) 2005-12-29 2019-07-10 Guselkumab, se følgebrevet for nærmere forklaring
NO20190992A NO347867B1 (no) 2005-12-29 2019-08-16 Isolerte IL-23p19 antistoffer, nukleinsyremolekyler, vektorer og vertsceller, samt sammensetninger, fremgangsmåter og en medisinsk anordning, og en artikkel.

Country Status (37)

Country Link
US (9) US7935344B2 (no)
EP (4) EP2548577B1 (no)
JP (1) JP5193881B2 (no)
KR (1) KR101210395B1 (no)
CN (2) CN102887954B (no)
AU (1) AU2006330411B2 (no)
BR (1) BRPI0620946B8 (no)
CA (1) CA2635692C (no)
CR (1) CR10181A (no)
CY (4) CY1115935T1 (no)
DK (3) DK1971366T3 (no)
EA (2) EA035459B1 (no)
EC (1) ECSP088591A (no)
ES (3) ES2622602T3 (no)
GT (1) GT200800132A (no)
HK (1) HK1124548A1 (no)
HN (1) HN2008000988A (no)
HR (3) HRP20140982T1 (no)
HU (3) HUE049832T2 (no)
IL (5) IL192458A (no)
LT (3) LT3219328T (no)
LU (1) LUC00071I2 (no)
MX (2) MX2008008621A (no)
MY (2) MY162559A (no)
NI (1) NI200800193A (no)
NL (1) NL300935I2 (no)
NO (4) NO343345B1 (no)
NZ (1) NZ569546A (no)
PL (3) PL1971366T3 (no)
PT (3) PT3219328T (no)
RS (3) RS55963B1 (no)
SG (1) SG10201505755YA (no)
SI (3) SI1971366T1 (no)
SV (1) SV2008002972A (no)
UA (1) UA101301C2 (no)
WO (1) WO2007076524A2 (no)
ZA (1) ZA200806556B (no)

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EA013506B1 (ru) * 2005-08-25 2010-06-30 Эли Лилли Энд Компани Антитело к il-23 и его применение
EP1931710B1 (en) 2005-08-31 2017-01-18 Merck Sharp & Dohme Corp. Engineered anti-il-23 antibodies
BRPI0615297A2 (pt) 2005-09-01 2011-05-17 Schering Corp antagonistas de il-23 e de il-17 para tratar doença inflamatória ocular auto-imune e seus usos
EA035459B1 (ru) * 2005-12-29 2020-06-19 Сентокор, Инк. Антитело против il-23p19
US7910703B2 (en) 2006-03-10 2011-03-22 Zymogenetics, Inc. Antagonists to IL-17A, IL-17F, and IL-23P19 and methods of use
EP2044118A2 (en) 2006-06-13 2009-04-08 Zymogenetics, Inc. Il-17 and il-23 antagonists and methods of using the same
TWI426918B (zh) 2007-02-12 2014-02-21 Merck Sharp & Dohme Il-23拮抗劑於治療感染之用途
PT2059534E (pt) 2007-02-23 2012-07-17 Schering Corp Anticorpos anti-il-23p19 fabricados por engenharia genética
EP2064242A1 (en) 2007-02-23 2009-06-03 Schering Corporation Engineered anti-il-23p19 antibodies
EP2417974A1 (en) 2007-02-28 2012-02-15 Schering Corporation Combination therapy for treatment of immune disorders
WO2009042162A2 (en) 2007-09-25 2009-04-02 Genzyme Corporation Compositions and methods for inhibiting interleukin pathways
AU2008328779B2 (en) * 2007-11-27 2014-06-05 Ablynx N.V. Amino acid sequences directed against HER2 and polypeptides comprising the same for the treatment of cancers and/or tumors
CN103251948A (zh) 2008-04-11 2013-08-21 中外制药株式会社 与多个分子的抗原反复结合的抗原结合分子
JP5931442B2 (ja) * 2008-08-27 2016-06-08 メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. 操作された抗IL−23p19抗体の凍結乾燥製剤
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