LU90190B1 - Fungizides Mittel eine Verbindung hierfuer Verfahren zu ihrer Herstellung und Verfahren zu ihrer Verwendung - Google Patents
Fungizides Mittel eine Verbindung hierfuer Verfahren zu ihrer Herstellung und Verfahren zu ihrer VerwendungInfo
- Publication number
- LU90190B1 LU90190B1 LU90190A LU90190A LU90190B1 LU 90190 B1 LU90190 B1 LU 90190B1 LU 90190 A LU90190 A LU 90190A LU 90190 A LU90190 A LU 90190A LU 90190 B1 LU90190 B1 LU 90190B1
- Authority
- LU
- Luxembourg
- Prior art keywords
- processes
- compound
- preparation
- fungicidal composition
- fungicidal
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP19617495 | 1995-07-08 | ||
PCT/JP1996/001872 WO1997002821A2 (en) | 1995-07-08 | 1996-07-05 | Antifungal agent, compound therefor, process for producing the same |
Publications (1)
Publication Number | Publication Date |
---|---|
LU90190B1 true LU90190B1 (de) | 1998-03-02 |
Family
ID=16353435
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
LU90190A LU90190B1 (de) | 1995-07-08 | 1997-12-31 | Fungizides Mittel eine Verbindung hierfuer Verfahren zu ihrer Herstellung und Verfahren zu ihrer Verwendung |
Country Status (22)
Country | Link |
---|---|
US (1) | US5900488A (de) |
EP (1) | EP0839035B1 (de) |
KR (1) | KR100386491B1 (de) |
CN (1) | CN1091596C (de) |
AT (1) | AT407832B (de) |
CA (1) | CA2226214C (de) |
CH (1) | CH692045A5 (de) |
DE (1) | DE19681478B4 (de) |
DK (1) | DK176599B1 (de) |
ES (1) | ES2137888B1 (de) |
FI (1) | FI119357B (de) |
GB (1) | GB2317615B (de) |
HK (1) | HK1009751A1 (de) |
IL (1) | IL122618A (de) |
IN (1) | IN185384B (de) |
LU (1) | LU90190B1 (de) |
NO (1) | NO980055L (de) |
NZ (1) | NZ311796A (de) |
SE (1) | SE9800016L (de) |
TW (1) | TW450969B (de) |
WO (1) | WO1997002821A2 (de) |
ZA (1) | ZA965745B (de) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6127397A (en) * | 1996-12-10 | 2000-10-03 | Nihon Nohyaku Co., Ltd. | Optically active (R)-(E)-(4-substituted-phenyl-1,3-dithiolan-2-ylidene)-1-imidazolylaceto nitrile derivative, antifungal composition comprising the same, and method for producing the same |
AU2003242235A1 (en) * | 2002-06-18 | 2003-12-31 | Pola Chemical Industries Inc. | Antifungal medicinal composition |
EP1537868B1 (de) | 2002-06-18 | 2011-08-24 | Pola Pharma Inc. | Antimykotische medizinische zusammensetzungen |
ES2421613T3 (es) * | 2006-03-08 | 2013-09-04 | Nihon Nohyaku Co Ltd | Composición farmacéutica externa |
WO2007102241A1 (ja) * | 2006-03-08 | 2007-09-13 | Nihon Nohyaku Co., Ltd. | 外用の医薬組成物 |
US8058303B2 (en) | 2006-03-08 | 2011-11-15 | Nihon Nohyaku Co, Ltd | Pharmaceutical composition for external use |
KR101184834B1 (ko) | 2007-08-27 | 2012-09-20 | 니혼노야쿠가부시키가이샤 | 진균성 피부염용제 |
US20100204293A1 (en) | 2007-09-05 | 2010-08-12 | Pola Pharma Inc. | Pharmaceutical composition |
CN101808638B (zh) | 2007-09-05 | 2012-07-25 | 宝丽制药股份有限公司 | 抗真菌组合物 |
PL2191828T3 (pl) | 2007-09-05 | 2017-02-28 | Pola Pharma Inc. | Przeciwgrzybicza kompozycja farmaceutyczna |
EP2395839B1 (de) * | 2009-02-13 | 2014-05-07 | Topica Pharmaceuticals, Inc | Antimykotische formulierung |
KR101409792B1 (ko) | 2009-04-09 | 2014-06-19 | 니혼노야쿠가부시키가이샤 | 항진균성 약제학적 조성물 |
US10130610B2 (en) | 2009-04-09 | 2018-11-20 | Pola Pharma Inc. | Antimycotic pharmaceutical composition |
JP5635075B2 (ja) | 2009-08-25 | 2014-12-03 | 株式会社ポーラファルマ | 抗真菌医薬組成物 |
WO2011155640A1 (en) * | 2010-06-11 | 2011-12-15 | Pola Pharma Inc. | Antimycotic pharmaceutical composition |
CN103012385B (zh) * | 2012-02-17 | 2015-07-08 | 山东威智医药工业有限公司 | 卢立康唑的晶型及其制备方法 |
CN104284662A (zh) * | 2012-09-14 | 2015-01-14 | 宝丽制药股份有限公司 | 晶体及包含该晶体的药物制剂 |
JP5460797B1 (ja) | 2012-09-14 | 2014-04-02 | 株式会社ポーラファルマ | アミド誘導体及び安定性指標としてのその使用 |
US9068958B1 (en) | 2012-09-14 | 2015-06-30 | Pola Pharma Inc. | Use of surface free energy for differential evaluation of crystal, crystal evaluated on basis of surface free energy as index, and pharmaceutical composition prepared by containing the crystal |
IN2015DN02376A (de) * | 2012-09-14 | 2015-09-04 | Pola Pharma Inc | |
EP2948145A1 (de) * | 2013-01-28 | 2015-12-02 | Pola Pharma Inc. | Pharmazeutische zusammensetzung gegen durch pathogene mikroorganismen wie aspergillus erregte krankheiten |
US20150352078A1 (en) * | 2013-01-28 | 2015-12-10 | Pola Pharma Inc. | Pharmaceutical composition for diseases caused by pathogenic microorganisms such as candida |
JP5589110B1 (ja) | 2013-03-08 | 2014-09-10 | 株式会社ポーラファルマ | 晶癖を有する結晶及び該結晶を有効成分として含有する医薬組成物 |
JP5680161B1 (ja) | 2013-09-06 | 2015-03-04 | 株式会社ポーラファルマ | 晶癖を有する結晶及び該結晶を有効成分として含有する医薬組成物 |
JP5587488B1 (ja) | 2013-12-12 | 2014-09-10 | 株式会社ポーラファルマ | ルリコナゾールを含有する製剤の評価方法及び指標物質 |
AR100180A1 (es) * | 2014-04-25 | 2016-09-14 | Syngenta Participations Ag | Derivados de imidazol microbiocidas |
EP3230280A4 (de) * | 2014-12-12 | 2018-05-09 | Glenmark Pharmaceuticals Limited | Verfahren zur herstellung von luliconazol |
WO2017108972A1 (en) | 2015-12-21 | 2017-06-29 | Laboratorios Lesvi, S.L. | Compounds of r-(-)-(e)-[4-(2,4-dichlorophenyl)-1,3-dithiolan-2-ylidene]-1 -imidazolylacetonitrile-ha (luliconazole-ha) as antifungals |
CN106008166B (zh) * | 2016-05-17 | 2018-09-25 | 上海福乐医药科技有限公司 | 一种手性2-氯-1-(2,4-二氯苯基)乙醇的工业化生产方法 |
WO2018115319A2 (en) | 2016-12-23 | 2018-06-28 | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) | Inhibitors of cytochrome p450 family 7 subfamily b member 1 (cyp7b1) for use in treating diseases |
TR201714882A2 (tr) | 2017-10-03 | 2019-04-22 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | Luli̇konazolün topi̇kal farmasöti̇k kompozi̇syonlari |
US10898470B1 (en) | 2019-08-13 | 2021-01-26 | Sato Pharmaceutical Co., Ltd. | Pharmaceutical composition containing antifungal agent as active ingredient |
WO2023131969A1 (en) * | 2022-01-09 | 2023-07-13 | Kimia Biosciences Limited | Improved process for the preparation of luliconazole |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0218736B1 (de) * | 1985-10-10 | 1993-04-07 | Nihon Nohyaku Co., Ltd. | Keten-S,S,-acetalderivate, Verfahren zu ihrer Herstellung und Methode zur Heilung von Mykose unter Verwendung dieser Derivate |
DE3587252T2 (de) * | 1985-10-09 | 1993-07-15 | Nihon Nohyaku Co Ltd | Keten-s,s,-acetalderivate, verfahren zu ihrer herstellung und methode zur heilung von mykose unter verwendung dieser derivate. |
JP3030780B2 (ja) * | 1988-12-29 | 2000-04-10 | 日本農薬株式会社 | 光学活性なケテンジチオアセタール誘導体及びその製造方法 |
JPH0386337A (ja) * | 1989-08-28 | 1991-04-11 | Maeda Seisakusho:Kk | エクスパンディングチャックを用いた多重巻締め機および多重巻締め方法 |
CN1038247C (zh) * | 1990-05-16 | 1998-05-06 | 云南省建筑材料科学研究设计院 | 一种新型磷石膏胶结料 |
JP3038519B2 (ja) * | 1992-01-28 | 2000-05-08 | 日本農薬株式会社 | 創傷治癒促進剤 |
-
1996
- 1996-07-05 GB GB9726766A patent/GB2317615B/en not_active Expired - Lifetime
- 1996-07-05 US US08/981,420 patent/US5900488A/en not_active Expired - Lifetime
- 1996-07-05 NZ NZ311796A patent/NZ311796A/xx not_active IP Right Cessation
- 1996-07-05 KR KR10-1998-0700071A patent/KR100386491B1/ko not_active IP Right Cessation
- 1996-07-05 ES ES009750013A patent/ES2137888B1/es not_active Expired - Fee Related
- 1996-07-05 CA CA002226214A patent/CA2226214C/en not_active Expired - Lifetime
- 1996-07-05 CN CN96196659A patent/CN1091596C/zh not_active Expired - Lifetime
- 1996-07-05 WO PCT/JP1996/001872 patent/WO1997002821A2/en active IP Right Grant
- 1996-07-05 CH CH00023/98A patent/CH692045A5/de not_active IP Right Cessation
- 1996-07-05 DE DE19681478T patent/DE19681478B4/de not_active Expired - Lifetime
- 1996-07-05 IN IN1499DE1996 patent/IN185384B/en unknown
- 1996-07-05 AT AT0906196A patent/AT407832B/de not_active IP Right Cessation
- 1996-07-05 ZA ZA965745A patent/ZA965745B/xx unknown
- 1996-07-05 EP EP96922243A patent/EP0839035B1/de not_active Expired - Lifetime
- 1996-07-05 IL IL12261896A patent/IL122618A/en not_active IP Right Cessation
- 1996-07-06 TW TW085108169A patent/TW450969B/zh not_active IP Right Cessation
-
1997
- 1997-12-31 LU LU90190A patent/LU90190B1/de active
-
1998
- 1998-01-06 NO NO980055A patent/NO980055L/no not_active Application Discontinuation
- 1998-01-07 FI FI980023A patent/FI119357B/fi not_active IP Right Cessation
- 1998-01-07 DK DK199800013A patent/DK176599B1/da not_active IP Right Cessation
- 1998-01-07 SE SE9800016A patent/SE9800016L/xx not_active Application Discontinuation
- 1998-09-18 HK HK98110741A patent/HK1009751A1/xx not_active IP Right Cessation
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