LU87412A1 - Nouvelle utilisation d'inhibiteurs de catechol-0-methyl transferase(comt)et de leurs esters et sels physiologiquement acceptables - Google Patents

Nouvelle utilisation d'inhibiteurs de catechol-0-methyl transferase(comt)et de leurs esters et sels physiologiquement acceptables Download PDF

Info

Publication number
LU87412A1
LU87412A1 LU87412A LU87412A LU87412A1 LU 87412 A1 LU87412 A1 LU 87412A1 LU 87412 A LU87412 A LU 87412A LU 87412 A LU87412 A LU 87412A LU 87412 A1 LU87412 A1 LU 87412A1
Authority
LU
Luxembourg
Prior art keywords
radical
use according
compound used
dihydroxy
optionally substituted
Prior art date
Application number
LU87412A
Other languages
English (en)
French (fr)
Inventor
Aho Paeivi
Pohto Pentti
Linden Inge-Britt
Baeckstroem Reijo
Honkanen Erkki
Nissinen Erkki
Original Assignee
Orion Yhtymae Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB878730190A external-priority patent/GB8730190D0/en
Application filed by Orion Yhtymae Oy filed Critical Orion Yhtymae Oy
Publication of LU87412A1 publication Critical patent/LU87412A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A61K31/06—Phenols the aromatic ring being substituted by nitro groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
LU87412A 1987-12-24 1988-12-22 Nouvelle utilisation d'inhibiteurs de catechol-0-methyl transferase(comt)et de leurs esters et sels physiologiquement acceptables LU87412A1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB878730190A GB8730190D0 (en) 1987-12-24 1987-12-24 New use of catechol-o-methyl transferase(comt)inhibitors & their physiologically acceptable salts & esters
GB8730190 1987-12-24
GB888820729A GB8820729D0 (en) 1987-12-24 1988-09-01 Substituted beta-diketones
GB8820729 1988-09-01

Publications (1)

Publication Number Publication Date
LU87412A1 true LU87412A1 (fr) 1989-06-14

Family

ID=26293247

Family Applications (1)

Application Number Title Priority Date Filing Date
LU87412A LU87412A1 (fr) 1987-12-24 1988-12-22 Nouvelle utilisation d'inhibiteurs de catechol-0-methyl transferase(comt)et de leurs esters et sels physiologiquement acceptables

Country Status (17)

Country Link
US (1) US5001152A (it)
EP (1) EP0323162B1 (it)
JP (1) JPH02196715A (it)
AU (1) AU617397B2 (it)
BE (1) BE1003759A5 (it)
CH (1) CH683395A5 (it)
DE (1) DE3843324A1 (it)
DK (1) DK713288A (it)
ES (1) ES2059546T3 (it)
HU (1) HU200684B (it)
IE (1) IE883816L (it)
IL (1) IL88734A (it)
IT (1) IT1227914B (it)
LU (1) LU87412A1 (it)
MT (1) MTP1031B (it)
PH (1) PH27037A (it)
SE (1) SE8804608L (it)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5283352A (en) * 1986-11-28 1994-02-01 Orion-Yhtyma Oy Pharmacologically active compounds, methods for the preparation thereof and compositions containing the same
GB9004348D0 (en) * 1990-02-27 1990-04-25 Orion Yhtymae Oy New use of catechol derivatives and their physiologically acceptable salts and esters
GB9002337D0 (en) * 1990-02-02 1990-04-04 Orion Yhtymae Oy Compounds useful in treating inflammatory bowel disease
IL91382A (en) * 1988-09-01 1995-06-29 Orion Yhtymae Oy Dicitons are converted into alkanyl or ethylmethylene, through their preparation and pharmaceutical preparations containing them
US5185370A (en) * 1988-09-01 1993-02-09 Orion-Yhtyma Oy Substituted β-diketones and their use
JPH05301838A (ja) * 1991-10-15 1993-11-16 Mitsubishi Kasei Corp スチレン誘導体
GB9626472D0 (en) * 1996-12-20 1997-02-05 Aperia Anita C New use of comt inhibitors
FI981521A0 (fi) 1998-07-01 1998-07-01 Orion Corp Substituoidut beta-diketonit ja niiden käyttö
FI20000635A0 (fi) * 2000-03-17 2000-03-17 Orion Yhtymae Oyj COMT-inhibiittoreiden käyttö analgeettina
GB0015228D0 (en) * 2000-06-21 2000-08-16 Portela & Ca Sa Substituted nitrated catechols, their use in the treatment of some central and peripheral nervous system disorders

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB902586A (en) * 1960-01-01 1962-08-01 Shell Res Ltd Herbicidal compositions and novel compounds for use therein
GB1188364A (en) * 1967-05-02 1970-04-15 May & Baker Ltd Quinoline Derivatives
BE759266A (fr) * 1969-11-24 1971-05-24 Hoffmann La Roche Procede pour la preparation de derives de l'indole
CA1190223A (en) * 1977-11-01 1985-07-09 Anthony C. Richardson Substrates for enzymes
FR2504004A1 (fr) * 1981-04-17 1982-10-22 Roussel Uclaf Application a titre de medicaments de derives d'acides phenyl aliphatique carboxyliques
JPS5890534A (ja) * 1981-11-25 1983-05-30 Ono Pharmaceut Co Ltd ２−アミノフエノ−ル誘導体、その製造方法およびその誘導体を有効成分として含有する治療剤
SU1424729A3 (ru) * 1983-05-13 1988-09-15 Яманоути Фармасьютикал Ко,Лтд (Фирма) Способ получени производных катехина
FR2557098B1 (fr) * 1983-12-22 1986-06-13 Rhone Poulenc Spec Chim Procede de preparation de bromobenzaldehydes hydroxy et/ou alkoxy substitues
FR2557097B1 (fr) * 1983-12-22 1986-06-13 Rhone Poulenc Spec Chim Procede de preparation de bromobenzaldehydes hydroxy et/ou alkoxy substitues
US4760089A (en) * 1985-09-09 1988-07-26 Smithkline Beckman Corporation Irreversible dopamine-β-hydroxylase inhibitors
DK175069B1 (da) * 1986-03-11 2004-05-24 Hoffmann La Roche Pyrocatecholderivater
YU213587A (en) * 1986-11-28 1989-06-30 Orion Yhtymae Oy Process for obtaining new pharmacologic active cateholic derivatives
DK49688A (da) * 1987-03-20 1988-09-21 Hoffmann La Roche Propiolophenonderivater

Also Published As

Publication number Publication date
EP0323162B1 (en) 1993-09-15
HUT49053A (en) 1989-08-28
PH27037A (en) 1993-02-01
BE1003759A5 (fr) 1992-06-09
SE8804608L (sv) 1989-06-25
MTP1031B (en) 1990-10-04
US5001152A (en) 1991-03-19
EP0323162A3 (en) 1990-11-14
DE3843324A1 (de) 1989-07-06
DK713288D0 (da) 1988-12-21
EP0323162A2 (en) 1989-07-05
AU617397B2 (en) 1991-11-28
CH683395A5 (de) 1994-03-15
AU2745988A (en) 1989-06-29
HU200684B (en) 1990-08-28
IL88734A0 (en) 1989-07-31
IT1227914B (it) 1991-05-14
ES2059546T3 (es) 1994-11-16
IT8823107A0 (it) 1988-12-23
JPH02196715A (ja) 1990-08-03
IL88734A (en) 1994-01-25
DK713288A (da) 1989-06-25
SE8804608D0 (sv) 1988-12-21
IE883816L (en) 1989-06-24

Similar Documents

Publication Publication Date Title
US6242488B1 (en) Method for preventing and treating pain
US6127418A (en) GABA analogs to prevent and treat gastrointestinal damage
DE69936150T2 (de) Indomethacin-amidderivate zur antiangiogenen und/oder antitumorigen verwendung
US10765630B2 (en) Methods and compositions to treat enteropathic arthritis
LU87412A1 (fr) Nouvelle utilisation d'inhibiteurs de catechol-0-methyl transferase(comt)et de leurs esters et sels physiologiquement acceptables
Derle et al. Adverse effects associated with the use of nonsteroidal antiinflammatory drugs: An overview
KR20050057673A (ko) Ｊｎｋ 억제제를 이용한 통증의 치료
FR2639226A1 (fr) Utilisation de trifluoromethylphenyltetrahydropyridines pour la preparation de medicaments destines a combattre les troubles anxio-depressifs
CA2503211C (fr) Composition pharmaceutique associant le tenatoprazole et un anti-inflammatoire
Satoh et al. Proton pump inhibitors prevent gastric antral ulcers induced by NSAIDs via activation of capsaicin-sensitive afferent nerves in mice
FR2690847A1 (fr) Compositions à activité agoniste des récepteurs analogues à 5HT1 sélective.
CN110290788A (zh) 氨基甲酸酯化合物用于预防、缓解或治疗双相障碍的用途
FR2464715A1 (fr) Utilisation de derives de glycerylphosphoryle dans la therapie des dyslipemies, des hepatites et des etats pathologiques analogues et compositions pharmaceutiques pour cette therapie
EP1317263A1 (fr) Utilisation d'une rheine pour la preparation d'un medicament pour la prevention de la degradation du cartilage articulaire
US9132108B2 (en) Pharmaceutical composition for ameliorating and/or preventing leptin resistance, and use thereof
EP3743059B1 (fr) Dérivés aminoacides contenant un groupement disulfanyle sous forme d'un inhibiteur de nep et d'apn pour la prévention et le traitement des douleurs relatives au nerf trijumeau
WO2006046746A1 (ja) 内臓痛予防・治療剤
WO2019055939A1 (en) METHODS AND COMPOSITIONS FOR INHIBITING SYMPTOMS ASSOCIATED WITH OPIOID WEANING
EP2184284B1 (en) Preventive, inhibitor or remedy for cerebral aneurysm comprising ibudilast as an active ingredient
FR2771005A1 (fr) Nouvelle association pharmaceutique a activite analgesique
EP0099775A1 (fr) Application du N-(diéthylaminoéthyl) 2-méthoxy-5-méthylsulfonyl benzamide dans l'inhibition de la tryptophane pyrrolase
CA1227136A (fr) Compositions pharmaceutiques contenant a titre de principe actif l'acide 4-(benzofuran-2-yl)4-oxo buten-2-oique et/ou de ses sels pharmaceutiquement acceptables
FR2521997A1 (fr) Nouvelle association medicamenteuse a base de morniflumate
KR101324689B1 (ko) 1-(3-클로로페닐)-3-알킬파이퍼라진을 포함하는 식욕 장애 치료용 약학 조성물
JP2021123530A (ja) 多発性骨髄腫の治療剤