MTP1031B - New use of cathecol-o-methyl transferase (comt) inhibitors and their physiologically acceptable salts and esters - Google Patents

New use of cathecol-o-methyl transferase (comt) inhibitors and their physiologically acceptable salts and esters

Info

Publication number
MTP1031B
MTP1031B MT1031A MTP1031A MTP1031B MT P1031 B MTP1031 B MT P1031B MT 1031 A MT1031 A MT 1031A MT P1031 A MTP1031 A MT P1031A MT P1031 B MTP1031 B MT P1031B
Authority
MT
Malta
Prior art keywords
cathecol
comt
inhibitors
esters
acceptable salts
Prior art date
Application number
MT1031A
Other languages
English (en)
Inventor
Aho Paeivi
Pohto Pentti
Linden Inge-Britt
Baechstroem Reijo
Honkanen Erkki
Nissinen Erkki
Original Assignee
Orion Yhtymae Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB878730190A external-priority patent/GB8730190D0/en
Application filed by Orion Yhtymae Oy filed Critical Orion Yhtymae Oy
Publication of MTP1031B publication Critical patent/MTP1031B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A61K31/06—Phenols the aromatic ring being substituted by nitro groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
MT1031A 1987-12-24 1988-12-16 New use of cathecol-o-methyl transferase (comt) inhibitors and their physiologically acceptable salts and esters MTP1031B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB878730190A GB8730190D0 (en) 1987-12-24 1987-12-24 New use of catechol-o-methyl transferase(comt)inhibitors & their physiologically acceptable salts & esters
GB888820729A GB8820729D0 (en) 1987-12-24 1988-09-01 Substituted beta-diketones

Publications (1)

Publication Number Publication Date
MTP1031B true MTP1031B (en) 1990-10-04

Family

ID=26293247

Family Applications (1)

Application Number Title Priority Date Filing Date
MT1031A MTP1031B (en) 1987-12-24 1988-12-16 New use of cathecol-o-methyl transferase (comt) inhibitors and their physiologically acceptable salts and esters

Country Status (17)

Country Link
US (1) US5001152A (xx)
EP (1) EP0323162B1 (xx)
JP (1) JPH02196715A (xx)
AU (1) AU617397B2 (xx)
BE (1) BE1003759A5 (xx)
CH (1) CH683395A5 (xx)
DE (1) DE3843324A1 (xx)
DK (1) DK713288A (xx)
ES (1) ES2059546T3 (xx)
HU (1) HU200684B (xx)
IE (1) IE883816L (xx)
IL (1) IL88734A (xx)
IT (1) IT1227914B (xx)
LU (1) LU87412A1 (xx)
MT (1) MTP1031B (xx)
PH (1) PH27037A (xx)
SE (1) SE8804608L (xx)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5283352A (en) * 1986-11-28 1994-02-01 Orion-Yhtyma Oy Pharmacologically active compounds, methods for the preparation thereof and compositions containing the same
GB9004348D0 (en) * 1990-02-27 1990-04-25 Orion Yhtymae Oy New use of catechol derivatives and their physiologically acceptable salts and esters
GB9002337D0 (en) * 1990-02-02 1990-04-04 Orion Yhtymae Oy Compounds useful in treating inflammatory bowel disease
US5185370A (en) * 1988-09-01 1993-02-09 Orion-Yhtyma Oy Substituted β-diketones and their use
IL91382A (en) * 1988-09-01 1995-06-29 Orion Yhtymae Oy Dicitons are converted into alkanyl or ethylmethylene, through their preparation and pharmaceutical preparations containing them
JPH05301838A (ja) * 1991-10-15 1993-11-16 Mitsubishi Kasei Corp スチレン誘導体
GB9626472D0 (en) * 1996-12-20 1997-02-05 Aperia Anita C New use of comt inhibitors
FI981521A0 (fi) 1998-07-01 1998-07-01 Orion Corp Substituoidut beta-diketonit ja niiden käyttö
FI20000635A0 (fi) * 2000-03-17 2000-03-17 Orion Yhtymae Oyj COMT-inhibiittoreiden käyttö analgeettina
GB0015228D0 (en) * 2000-06-21 2000-08-16 Portela & Ca Sa Substituted nitrated catechols, their use in the treatment of some central and peripheral nervous system disorders

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB902586A (en) * 1960-01-01 1962-08-01 Shell Res Ltd Herbicidal compositions and novel compounds for use therein
GB1188364A (en) * 1967-05-02 1970-04-15 May & Baker Ltd Quinoline Derivatives
BE759266A (fr) * 1969-11-24 1971-05-24 Hoffmann La Roche Procede pour la preparation de derives de l'indole
CA1190223A (en) * 1977-11-01 1985-07-09 Anthony C. Richardson Substrates for enzymes
FR2504004A1 (fr) * 1981-04-17 1982-10-22 Roussel Uclaf Application a titre de medicaments de derives d'acides phenyl aliphatique carboxyliques
JPS5890534A (ja) * 1981-11-25 1983-05-30 Ono Pharmaceut Co Ltd ２−アミノフエノ−ル誘導体、その製造方法およびその誘導体を有効成分として含有する治療剤
SU1424729A3 (ru) * 1983-05-13 1988-09-15 Яманоути Фармасьютикал Ко,Лтд (Фирма) Способ получени производных катехина
FR2557098B1 (fr) * 1983-12-22 1986-06-13 Rhone Poulenc Spec Chim Procede de preparation de bromobenzaldehydes hydroxy et/ou alkoxy substitues
FR2557097B1 (fr) * 1983-12-22 1986-06-13 Rhone Poulenc Spec Chim Procede de preparation de bromobenzaldehydes hydroxy et/ou alkoxy substitues
US4760089A (en) * 1985-09-09 1988-07-26 Smithkline Beckman Corporation Irreversible dopamine-β-hydroxylase inhibitors
DK175069B1 (da) * 1986-03-11 2004-05-24 Hoffmann La Roche Pyrocatecholderivater
YU213587A (en) * 1986-11-28 1989-06-30 Orion Yhtymae Oy Process for obtaining new pharmacologic active cateholic derivatives
DK49688A (da) * 1987-03-20 1988-09-21 Hoffmann La Roche Propiolophenonderivater

Also Published As

Publication number Publication date
AU617397B2 (en) 1991-11-28
LU87412A1 (fr) 1989-06-14
IL88734A0 (en) 1989-07-31
BE1003759A5 (fr) 1992-06-09
IT8823107A0 (it) 1988-12-23
DK713288A (da) 1989-06-25
SE8804608D0 (sv) 1988-12-21
EP0323162B1 (en) 1993-09-15
EP0323162A3 (en) 1990-11-14
IE883816L (en) 1989-06-24
IT1227914B (it) 1991-05-14
SE8804608L (sv) 1989-06-25
AU2745988A (en) 1989-06-29
DE3843324A1 (de) 1989-07-06
EP0323162A2 (en) 1989-07-05
JPH02196715A (ja) 1990-08-03
US5001152A (en) 1991-03-19
PH27037A (en) 1993-02-01
HU200684B (en) 1990-08-28
ES2059546T3 (es) 1994-11-16
DK713288D0 (da) 1988-12-21
IL88734A (en) 1994-01-25
CH683395A5 (de) 1994-03-15
HUT49053A (en) 1989-08-28

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