LU85961A1 - Nouveaux pro-medicaments heterocycliques d'oxicams anti-inflammatoires et leur procede de preparation - Google Patents

Nouveaux pro-medicaments heterocycliques d'oxicams anti-inflammatoires et leur procede de preparation Download PDF

Info

Publication number
LU85961A1
LU85961A1 LU85961A LU85961A LU85961A1 LU 85961 A1 LU85961 A1 LU 85961A1 LU 85961 A LU85961 A LU 85961A LU 85961 A LU85961 A LU 85961A LU 85961 A1 LU85961 A1 LU 85961A1
Authority
LU
Luxembourg
Prior art keywords
formula
compound
inflammatory
oxicams
acid acceptor
Prior art date
Application number
LU85961A
Other languages
English (en)
French (fr)
Inventor
Anthony Marfat
Joseph George Lombardino
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of LU85961A1 publication Critical patent/LU85961A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
    • C07D513/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
LU85961A 1984-06-21 1985-06-19 Nouveaux pro-medicaments heterocycliques d'oxicams anti-inflammatoires et leur procede de preparation LU85961A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US62325184 1984-06-21
US06/623,251 US4656265A (en) 1984-06-21 1984-06-21 Cyclic prodrugs of antiinflammatory oxicams

Publications (1)

Publication Number Publication Date
LU85961A1 true LU85961A1 (fr) 1986-01-24

Family

ID=24497355

Family Applications (1)

Application Number Title Priority Date Filing Date
LU85961A LU85961A1 (fr) 1984-06-21 1985-06-19 Nouveaux pro-medicaments heterocycliques d'oxicams anti-inflammatoires et leur procede de preparation

Country Status (29)

Country Link
US (1) US4656265A (nl)
JP (1) JPS6112692A (nl)
KR (1) KR870000627B1 (nl)
AT (1) AT393269B (nl)
AU (1) AU556117B2 (nl)
BE (1) BE902682A (nl)
CA (1) CA1234813A (nl)
CH (1) CH664157A5 (nl)
DE (1) DE3521722A1 (nl)
DK (1) DK171110B1 (nl)
EG (1) EG17534A (nl)
ES (1) ES8609333A1 (nl)
FI (1) FI852461L (nl)
FR (1) FR2566408B1 (nl)
GB (1) GB2160523B (nl)
GR (1) GR851489B (nl)
HU (1) HU196214B (nl)
IE (1) IE58135B1 (nl)
IL (1) IL75566A (nl)
IT (1) IT1190373B (nl)
LU (1) LU85961A1 (nl)
NL (1) NL193192C (nl)
NO (1) NO171727C (nl)
NZ (1) NZ212476A (nl)
PH (1) PH20816A (nl)
PL (1) PL146350B1 (nl)
PT (1) PT80664B (nl)
SE (1) SE456995B (nl)
ZA (1) ZA854649B (nl)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4656265A (en) * 1984-06-21 1987-04-07 Pfizer Inc. Cyclic prodrugs of antiinflammatory oxicams
FR2597103B1 (fr) * 1986-04-15 1988-12-16 Provesan Sa Procede de preparation de derives d'oxazinobenzothiazine 6,6-dioxyde
US5217968A (en) * 1989-04-06 1993-06-08 Pfizer Inc. N-alkylbenzo(b)thieno [3,2-b]oxazin-2,4-diones
US9666805B2 (en) * 2014-11-25 2017-05-30 Northwestern University Bithiophene sulfonamide-based molecular and polymeric semiconductors

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3492298A (en) * 1968-02-21 1970-01-27 Mcneilab Inc Oxazino-benzothiazine-6,6-dioxides
US3591584A (en) * 1968-08-27 1971-07-06 Pfizer Benzothiazine dioxides
US3787324A (en) * 1971-03-01 1974-01-22 Warner Lambert Co 4-hydroxy-3-(3-isoxazolocarbamyl)-2h-1,2-benzothiazine 1,dioxides and process for their production
US3923801A (en) * 1974-09-23 1975-12-02 Mcneilab Inc Oxazinobenzothiazine 6,6-dioxides
AU518216B2 (en) * 1977-09-06 1981-09-17 Hafslund Nycomed Pharma Aktiengesellschaft Thienothiazine derivatives
JPS5714589A (en) * 1980-06-27 1982-01-25 Mitsui Toatsu Chem Inc Benzothiazine derivative, its preparation and drug composition
US4309427A (en) * 1981-01-15 1982-01-05 Pfizer Inc. Benzothiazine dioxide derivatives
FR2528433A1 (fr) * 1982-06-15 1983-12-16 Provesan Sa Nouveaux derives d'oxazinobenzothiazine-6,6-dioxyde, leur preparation et leur application en tant que medicaments
US4656265A (en) * 1984-06-21 1987-04-07 Pfizer Inc. Cyclic prodrugs of antiinflammatory oxicams

Also Published As

Publication number Publication date
NZ212476A (en) 1988-08-30
IE851521L (en) 1985-12-21
PT80664A (en) 1985-07-01
CA1234813A (en) 1988-04-05
EG17534A (en) 1990-08-30
DK171110B1 (da) 1996-06-17
IL75566A (en) 1990-06-10
NL193192C (nl) 1999-02-02
NL8501776A (nl) 1986-01-16
DK274185D0 (da) 1985-06-18
JPS6112692A (ja) 1986-01-21
US4656265A (en) 1987-04-07
SE8503109D0 (sv) 1985-06-20
FI852461A0 (fi) 1985-06-20
ES8609333A1 (es) 1986-07-16
KR870000627B1 (ko) 1987-03-26
KR860000295A (ko) 1986-01-27
SE8503109L (sv) 1985-12-22
NL193192B (nl) 1998-10-01
PT80664B (pt) 1988-01-22
AU4386485A (en) 1986-01-02
GB8515437D0 (en) 1985-07-17
FI852461L (fi) 1985-12-22
NO171727C (no) 1993-04-28
IT8521218A0 (it) 1985-06-20
SE456995B (sv) 1988-11-21
BE902682A (fr) 1985-12-18
ES544397A0 (es) 1986-07-16
ATA180785A (de) 1991-02-15
DE3521722A1 (de) 1985-12-19
FR2566408B1 (fr) 1989-11-03
AT393269B (de) 1991-09-25
IT1190373B (it) 1988-02-16
PH20816A (en) 1987-04-24
ZA854649B (en) 1987-02-25
HUT44564A (en) 1988-03-28
AU556117B2 (en) 1986-10-23
IE58135B1 (en) 1993-07-14
JPH03874B2 (nl) 1991-01-09
GB2160523B (en) 1988-06-22
PL146350B1 (en) 1989-01-31
HU196214B (en) 1988-10-28
PL254117A1 (en) 1986-05-20
NO852490L (no) 1985-12-23
GR851489B (nl) 1985-11-25
FR2566408A1 (fr) 1985-12-27
CH664157A5 (fr) 1988-02-15
NO171727B (no) 1993-01-18
DK274185A (da) 1985-12-22
DE3521722C2 (nl) 1988-09-15
GB2160523A (en) 1985-12-24

Similar Documents

Publication Publication Date Title
EP0487408B1 (fr) Dérivés d'oxazolopyridines leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent
EP1373219A1 (fr) Thiohydantoines et leur utilisation dans le traitement du diabete
FR2754260A1 (fr) Nouveaux derives substitues de biphenyle ou de phenylpyridine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
CA2683933A1 (fr) Derives de triazolopyridine-carboxamides, leur preparation et leur application en therapeutique
EP1560826B1 (fr) Composes pyridopyrimidinone, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
EP1558612B1 (fr) Derives d'imidazopyridine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
WO1997003987A1 (fr) Nouveaux derives de la galanthamine, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant
EP0479631B1 (fr) Dérivés du spiro [4.5]décane leur procédé de préparation et les compositions pharmaceutiques les renfermant
LU85961A1 (fr) Nouveaux pro-medicaments heterocycliques d'oxicams anti-inflammatoires et leur procede de preparation
EP0573318A1 (fr) Nouveaux dérivés de phényle carboxamide isoxazoles et leurs sels, leur procédé de préparation et les nouveaux intermédiaires de ce procédé, leur application comme médicaments et les compositions pharmaceutiques les renfermant
WO1990003972A1 (fr) Derives de methyl-4 ((phenyl-4 piperazinyl-1)-2 ethyl)-5 thiazole
LU85780A1 (fr) Nouveaux esters enoliques precurseurs de medicaments et composition pharmaceutique les contenant
EP0002635A1 (fr) Procédé de préparation de dérivés de thiéno (2,3-c) et (3,2-c) pyridines, nouveaux dérivés de la thiéno (2,3-c) pyridine obtenus et leur application thérapeutique
EP0119896B1 (fr) Nouveaux dérivés de l'amino-5 dithiole-1,2 one-3, leur préparation et les compositions médicinales qui les contiennent
EP0705261A1 (fr) Naphtyridines antiproliferatives
EP0322296B1 (fr) Dérivés oxyimino du thiazole, procédé de préparation et utilisation en thérapeutique
EP0280627B1 (fr) Nouveaux dérivés N-substitués de l'alpha-mercaptométhyl benzène propanamide, leur procédé de préparation, leur application à titre de médicaments et les compositions les renfermant
EP0449728A1 (fr) Nouveaux dérivés de la 4H-pyrrolo (1,2-a)thieno(2,3-f) diazépine(1,4), leur procédé de préparation et les compositions pharmaceutiques les renfermant
CH632763A5 (en) Triazolothiadiazine derivatives and processes for preparing them
WO1995000513A1 (fr) Naphtyridines antiproliferatives
FR2932480A1 (fr) Phenyl-alkyl-piperazines ayant une activite modulatrice du tnf
EP2838899B1 (fr) Dérivés de thiazolidinedione, leur préparation et leur utilisation dans le traitement des cancers
FR2593501A1 (fr) Nouveaux derives bis (r-oxyimino)-5,7 dihydro-6,7 (5h) dibenzo (a,c) cycloheptene, leurs procedes de preparation et leur application comme medicaments
WO2011083265A1 (fr) Nouveaux derives de benzothiadiazines cyclopropylees, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
JPH0778063B2 (ja) Ｎ―アルケニルベンゾ［ｂチエノ［３，２―ｂオキサジン―２，４―ジオン