LU84564A1 - Nouveaux composes bicycliques et procede pour les preparer - Google Patents

Nouveaux composes bicycliques et procede pour les preparer Download PDF

Info

Publication number
LU84564A1
LU84564A1 LU84564A LU84564A LU84564A1 LU 84564 A1 LU84564 A1 LU 84564A1 LU 84564 A LU84564 A LU 84564A LU 84564 A LU84564 A LU 84564A LU 84564 A1 LU84564 A1 LU 84564A1
Authority
LU
Luxembourg
Prior art keywords
methyl
dioxolan
oxo
carboxylate
mixture
Prior art date
Application number
LU84564A
Other languages
English (en)
French (fr)
Inventor
Laszlo Dr Szporny
Karoly Dr Lempert
Gabor Dr Doleschall
Jozsef Dr Fetter
Gyula Dr Hornyak
Jozsef Dr Nyitrai
Gyula Dr Simig
Karoly Dr Zauer
Kalman Dr Harsanyi
Gyoergy Dr Fekete
Gyoergy Dr Hajos
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of LU84564A1 publication Critical patent/LU84564A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D207/28—2-Pyrrolidone-5- carboxylic acids; Functional derivatives thereof, e.g. esters, nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D411/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D411/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D411/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
LU84564A 1981-12-30 1982-12-29 Nouveaux composes bicycliques et procede pour les preparer LU84564A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU814017A HU185493B (en) 1981-12-30 1981-12-30 Process for producing new azabicyclo-bracket-3.2.0-bracket closedheptene derivatives
HU401781 1981-12-30

Publications (1)

Publication Number Publication Date
LU84564A1 true LU84564A1 (fr) 1984-10-22

Family

ID=10966528

Family Applications (1)

Application Number Title Priority Date Filing Date
LU84564A LU84564A1 (fr) 1981-12-30 1982-12-29 Nouveaux composes bicycliques et procede pour les preparer

Country Status (18)

Country Link
JP (1) JPS58118588A (ja)
AT (1) AT375944B (ja)
AU (1) AU9197382A (ja)
BE (1) BE895488A (ja)
CA (1) CA1192202A (ja)
DE (1) DE3248678A1 (ja)
ES (1) ES8405797A1 (ja)
FI (1) FI824518L (ja)
FR (1) FR2519002A1 (ja)
GB (1) GB2112391B (ja)
GR (1) GR78431B (ja)
HU (1) HU185493B (ja)
IT (1) IT1210971B (ja)
LU (1) LU84564A1 (ja)
NL (1) NL8205065A (ja)
PL (1) PL239887A1 (ja)
SE (1) SE8207480L (ja)
ZA (1) ZA829600B (ja)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1198440A (en) * 1982-04-08 1985-12-24 Choung U. Kim Carbapenem antibiotics
JPS6028981A (ja) * 1983-07-27 1985-02-14 Shionogi & Co Ltd ジオキソラニルペネムカルボン酸誘導体
CA2315056A1 (en) * 1997-12-16 1999-06-24 Terutaka Hashizume Carbapenem derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5625110A (en) * 1978-12-18 1981-03-10 Bristol Myers Co Antibacterial
IE52147B1 (en) * 1980-03-27 1987-07-08 Merck & Co Inc 4-(3-carboxy-2-oxopropyl)-azetidin-2-ones and process for their preparation
JPS57176982A (en) * 1981-04-24 1982-10-30 Shionogi & Co Ltd Dioxolanylazetidinone compound, its preparation and use

Also Published As

Publication number Publication date
ZA829600B (en) 1983-10-26
GR78431B (ja) 1984-09-27
PL239887A1 (en) 1984-01-02
IT1210971B (it) 1989-09-29
ATA450982A (de) 1984-02-15
GB2112391A (en) 1983-07-20
CA1192202A (en) 1985-08-20
AU9197382A (en) 1983-07-07
SE8207480L (sv) 1983-07-01
ES518725A0 (es) 1984-06-16
SE8207480D0 (sv) 1982-12-29
NL8205065A (nl) 1983-07-18
FI824518L (fi) 1983-07-01
IT8225065A0 (it) 1982-12-30
FR2519002A1 (fr) 1983-07-01
JPS58118588A (ja) 1983-07-14
ES8405797A1 (es) 1984-06-16
GB2112391B (en) 1985-10-16
AT375944B (de) 1984-09-25
DE3248678A1 (de) 1983-07-07
BE895488A (fr) 1983-06-28
HU185493B (en) 1985-02-28
FI824518A0 (fi) 1982-12-30

Similar Documents

Publication Publication Date Title
EP0248734A1 (fr) Dérivés de benzo[b]thiophène et benzo[b]furannecarboxamides, leurs procédés de préparation et les médicaments les contenant
FR2599739A1 (fr) Acides biphenyl hydroxamiques a action therapeutique
LU82334A1 (fr) Composes de pyranone substitues en position 5 et leur utilisation comme produits pharmaceutiques
LU84564A1 (fr) Nouveaux composes bicycliques et procede pour les preparer
BE881862A (fr) Composes antibacteriens et inhibiteurs de beta-lactamase, procede pour les preparer et leur usage comme medicaments
FR2618777A1 (fr) Benzazepines a action therapeutique
BE875053A (fr) Composes analogues aux cephalosporines
FR2518998A1 (fr) Nouveaux derives heterocycliques d'acide acetique et procede pour leur preparation
FR2792635A1 (fr) Derives de cyclobutene-3,4-dione leur preparation et leur application en therapeutique
FR2519001A1 (fr) Nouveaux composes bicycliques et procede pour les preparer
FR2518995A1 (fr) Procede de preparation de derives heterocycliques d'acide acetique et derives ainsi obtenus
FR2792634A1 (fr) Derives de 2-alcoxy-cyclobutene-3,4-dione leur preparation et leur application en therapeutique
LU84570A1 (fr) Procede pour la preparation de nouveaux composes bicycliques et composes ainsi obtenus
FR2719047A1 (fr) Nouveaux dérivés de benzylamines, leur procédé de fabrication et les compositions pharmaceutiques les renfermant.
FR2790472A1 (fr) Derives de cyclobutene-3, 4-dione, leur preparation et leur application en therapeutique
FR2518997A1 (fr) Nouveaux acides carboxyliques heterocycliques et procede pour les preparer
EP0161235A2 (fr) Nouveaux dérivés de thiénopyridinone, leur procédé de préparation et compositions pharmaceutiques les contenant
JPS6254310B2 (ja)
CA1038859A (fr) Derives de l'acide penicillanique, leur preparation et les compositions qui les contiennent____________________________________________________
FR2505332A1 (fr) Composes pour la synthese de prostaglandines et prostacyclines contenant de l'azote, et procede pour leur preparation
FR2518996A1 (fr) Nouveaux derives heterocycliques d'acide acetique et un procede pour leur preparation
CH632768A5 (fr) Procede pour l'obtention de n,n'-bis-(3-oxazolidinyl-2-one)-phosphoramides p-substitues et n,n'-bis-(3-oxazolidinyl-2-one)-phosphoramides p-substitues obtenu.
FR2523969A1 (fr) Procede de synthese d'hydroxyethyltetrazolethiols et nouveaux esters alkyliques d'acides n-(hydroxy protege ethyl)dithiocarbamiques et composes de 1-(hydroxy protege ethyl)-1h-tetrazole-5-thiol
FR2573764A1 (fr) Nouveaux derives d'imidazopyridazine, leur procede de production et composition pharmaceutique les contenant
EP0188150A1 (fr) Procédé de préparation d'isomères optiques de thiazolo [3,2-a] pyrimidines, les nouveaux isomères ainsi obtenus, les compositions pharmaceutiques qui les contiennent et les intermédiaires pour mettre en oeuvre ce procédé