LU83822A1 - Derives n-(vinblastinoyl-23)d'acides amines,leur preparation et leur application therapeutique - Google Patents

Derives n-(vinblastinoyl-23)d'acides amines,leur preparation et leur application therapeutique Download PDF

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Publication number
LU83822A1
LU83822A1 LU83822A LU83822A LU83822A1 LU 83822 A1 LU83822 A1 LU 83822A1 LU 83822 A LU83822 A LU 83822A LU 83822 A LU83822 A LU 83822A LU 83822 A1 LU83822 A1 LU 83822A1
Authority
LU
Luxembourg
Prior art keywords
group
ethyl
pharmaceutical composition
pharmaceutically acceptable
alkyl
Prior art date
Application number
LU83822A
Other languages
English (en)
French (fr)
Inventor
Andre Benoit Leon Trouet
Kandukuri Sivaprasada Bhus Rao
Jean Alfred Alphonse Hannart
Original Assignee
Omnichem Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Omnichem Sa filed Critical Omnichem Sa
Priority to LU83822A priority Critical patent/LU83822A1/fr
Priority to AU90847/82A priority patent/AU564951B2/en
Priority to IL67366A priority patent/IL67366A/xx
Priority to ZA828823A priority patent/ZA828823B/xx
Priority to CH6980/82A priority patent/CH655727A5/fr
Priority to US06/446,708 priority patent/US4639456A/en
Priority to CA000416996A priority patent/CA1198422A/en
Priority to NZ202708A priority patent/NZ202708A/en
Priority to NL8204711A priority patent/NL8204711A/nl
Priority to GR69997A priority patent/GR77280B/el
Priority to ES517942A priority patent/ES517942A0/es
Priority to FR828220476A priority patent/FR2517680B1/fr
Priority to IE2906/82A priority patent/IE55283B1/en
Priority to DK541882A priority patent/DK161833C/da
Priority to HU823919A priority patent/HU187803B/hu
Priority to DE19823245269 priority patent/DE3245269A1/de
Priority to SE8206981A priority patent/SE452622B/sv
Priority to BE0/209661A priority patent/BE895262A/fr
Priority to JP57214573A priority patent/JPS58116491A/ja
Priority to IT68431/82A priority patent/IT1157126B/it
Priority to PT75949A priority patent/PT75949B/pt
Priority to AT0444982A priority patent/AT390958B/de
Priority to OA57864A priority patent/OA07270A/xx
Priority to GB08234965A priority patent/GB2111055B/en
Priority to DD82245703A priority patent/DD205906A5/de
Publication of LU83822A1 publication Critical patent/LU83822A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
LU83822A 1980-06-10 1981-12-08 Derives n-(vinblastinoyl-23)d'acides amines,leur preparation et leur application therapeutique LU83822A1 (fr)

Priority Applications (25)

Application Number Priority Date Filing Date Title
LU83822A LU83822A1 (fr) 1981-12-08 1981-12-08 Derives n-(vinblastinoyl-23)d'acides amines,leur preparation et leur application therapeutique
AU90847/82A AU564951B2 (en) 1981-12-08 1982-11-24 Vinblastine derivatives
IL67366A IL67366A (en) 1981-12-08 1982-11-30 Derivatives of n-(vinblastinoyl-23)amino acids,their preparation and therapeutical application
ZA828823A ZA828823B (en) 1981-12-08 1982-12-01 N-(vinblastinoyl-23) derivatives of amino acids, their preparation and therapeutical application
CH6980/82A CH655727A5 (fr) 1981-12-08 1982-12-01 Derives n-(vinblastinoyl-23) d'acides amines et composition pharmaceutique les contenant.
US06/446,708 US4639456A (en) 1980-06-10 1982-12-03 Vinblastin-23-oyl amino acid derivatives
CA000416996A CA1198422A (en) 1981-12-08 1982-12-03 N-(vinblastinoyl-23) derivatives of amino acids, their preparation and therapeutical application
NZ202708A NZ202708A (en) 1981-12-08 1982-12-03 N-(vinblastinoyl-23)derivatives of amino acids,their preparation and pharmaceutical compositions
NL8204711A NL8204711A (nl) 1981-12-08 1982-12-06 N-(vinblastinoyl-23)derivaten van aminozuren, hun bereiding en therapeutische toepassing.
GR69997A GR77280B (it) 1981-12-08 1982-12-06
ES517942A ES517942A0 (es) 1981-12-08 1982-12-06 Procedimiento de obtener alcaloides bisindolicos.
FR828220476A FR2517680B1 (fr) 1981-12-08 1982-12-07 Derives n-(vinblastinoyl-23) d'acides amines, leur preparation et leur application therapeutique
IE2906/82A IE55283B1 (en) 1981-12-08 1982-12-07 N-(vinblastin-23-oyl)derivatives of amino acids
DK541882A DK161833C (da) 1981-12-08 1982-12-07 Analogifremgangsmaade til fremstilling af n-(vinblastinoyl-23)-derivater af aminosyrer eller farmaceutisk acceptable syreadditionssalte deraf
HU823919A HU187803B (en) 1981-12-08 1982-12-07 Process for producing n-bracket-vinblastinoyl-23-bracket closed-derivatives of amino acids and pharmaceutical compositions containing them
DE19823245269 DE3245269A1 (de) 1981-12-08 1982-12-07 N-(vinblastinoyl-23)-derivate von aminosaeuren, ihre herstellung und therapeutische anwendung
SE8206981A SE452622B (sv) 1981-12-08 1982-12-07 N-(vinblastinoyl-23)-derivat av aminosyror, deras framstellning och farmaceutiska kompositioner
BE0/209661A BE895262A (fr) 1981-12-08 1982-12-07 Derives n- (vinblastinoyl 23) d'acides amines, leur preparation et leur application therapeutique
JP57214573A JPS58116491A (ja) 1981-12-08 1982-12-07 アミノ酸のｎ―（ビンブラスチノイル―２３）誘導体及びそれを含有する薬剤組成物
IT68431/82A IT1157126B (it) 1981-12-08 1982-12-07 N(vinblastin-23-il)derivati di aminoacidi loro preparazione ed applicazione terapeutica
PT75949A PT75949B (fr) 1981-12-08 1982-12-07 Procede pour la preparation de derives d'acides amines en n-(vinblastinoil-23)
AT0444982A AT390958B (de) 1981-12-08 1982-12-07 Verfahren zur herstellung neuer bisindolalkaloidderivate
OA57864A OA07270A (fr) 1981-12-08 1982-12-08 Dérivés N-(vinblastinoyl-23) d'acide aminés, leur préparation et leur application thérapeutique.
GB08234965A GB2111055B (en) 1981-12-08 1982-12-08 N-(vinblastinoyl-23) derivative of amino acids
DD82245703A DD205906A5 (de) 1981-12-08 1982-12-08 Verfahren zur herstellung von n-(vinblastinoyl-23)-derivaten von aminosaeuren

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
LU83822 1981-12-08
LU83822A LU83822A1 (fr) 1981-12-08 1981-12-08 Derives n-(vinblastinoyl-23)d'acides amines,leur preparation et leur application therapeutique

Publications (1)

Publication Number Publication Date
LU83822A1 true LU83822A1 (fr) 1983-09-01

Family

ID=19729780

Family Applications (1)

Application Number Title Priority Date Filing Date
LU83822A LU83822A1 (fr) 1980-06-10 1981-12-08 Derives n-(vinblastinoyl-23)d'acides amines,leur preparation et leur application therapeutique

Country Status (24)

Country Link
JP (1) JPS58116491A (it)
AT (1) AT390958B (it)
AU (1) AU564951B2 (it)
BE (1) BE895262A (it)
CA (1) CA1198422A (it)
CH (1) CH655727A5 (it)
DD (1) DD205906A5 (it)
DE (1) DE3245269A1 (it)
DK (1) DK161833C (it)
ES (1) ES517942A0 (it)
FR (1) FR2517680B1 (it)
GB (1) GB2111055B (it)
GR (1) GR77280B (it)
HU (1) HU187803B (it)
IE (1) IE55283B1 (it)
IL (1) IL67366A (it)
IT (1) IT1157126B (it)
LU (1) LU83822A1 (it)
NL (1) NL8204711A (it)
NZ (1) NZ202708A (it)
OA (1) OA07270A (it)
PT (1) PT75949B (it)
SE (1) SE452622B (it)
ZA (1) ZA828823B (it)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR81790B (it) * 1983-04-29 1984-12-12 Omnichem Sa
US4667030A (en) * 1985-06-17 1987-05-19 Eli Lilly And Company Hydrazide succinimide derivatives of antineoplastic indole-dihydroindole alkaloids
US4675400A (en) * 1985-06-17 1987-06-23 Eli Lilly And Company Bifunctional derivatives of 4-desacetyl indole-dihydroindole alkaloids
EP0233101A1 (fr) * 1986-01-13 1987-08-19 Ire-Celltarg S.A. Dérivés de vinblastine et composition pharmaceutique les contenant
US4906086A (en) * 1987-06-19 1990-03-06 Honda Giken Kogyo Kabushiki Kaisha Rearview mirror device for motorcycles
FR2626882B1 (fr) * 1988-02-08 1991-11-08 Ire Celltarg Sa Conjugues de derives de vinca comportant une chaine detergente en position c-3
EP2987794B1 (en) * 2013-04-19 2018-05-30 Jinan University Vinblastine derivatives, preparation method therefor and application thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR204004A1 (es) * 1973-04-02 1975-11-12 Lilly Co Eli Procedimientos para preparar derivados de vinblastina leurosidina y leurocristina
US3848234A (en) * 1973-04-04 1974-11-12 Sperry Rand Corp Multi-processor system with multiple cache memories
IL48685A (en) * 1975-01-09 1980-03-31 Lilly Co Eli Amides of vincadioline and vinblastine
OA06421A (fr) * 1980-06-10 1981-09-30 Omnium Chimique Sa Procédé de préparation de dérivés N-(vinblastinoyl-23) d'acides aminés et de peptides.

Also Published As

Publication number Publication date
SE452622B (sv) 1987-12-07
IL67366A (en) 1987-01-30
IE55283B1 (en) 1990-08-01
FR2517680A1 (fr) 1983-06-10
NZ202708A (en) 1986-01-24
DD205906A5 (de) 1984-01-11
NL8204711A (nl) 1983-07-01
CH655727A5 (fr) 1986-05-15
ZA828823B (en) 1983-09-28
GR77280B (it) 1984-09-11
SE8206981L (sv) 1983-06-09
IT8268431A0 (it) 1982-12-07
JPH0449557B2 (it) 1992-08-11
JPS58116491A (ja) 1983-07-11
DK541882A (da) 1983-06-09
AU564951B2 (en) 1987-09-03
ES8401768A1 (es) 1984-01-01
IT1157126B (it) 1987-02-11
PT75949A (fr) 1983-01-01
SE8206981D0 (sv) 1982-12-07
DK161833C (da) 1992-01-20
FR2517680B1 (fr) 1990-05-25
ES517942A0 (es) 1984-01-01
ATA444982A (de) 1990-01-15
PT75949B (fr) 1985-10-04
BE895262A (fr) 1983-06-07
IL67366A0 (en) 1983-03-31
CA1198422A (en) 1985-12-24
GB2111055A (en) 1983-06-29
GB2111055B (en) 1985-07-10
AT390958B (de) 1990-07-25
OA07270A (fr) 1984-04-30
IE822906L (en) 1983-06-08
AU9084782A (en) 1983-06-16
HU187803B (en) 1986-02-28
DE3245269A1 (de) 1983-07-21
DK161833B (da) 1991-08-19

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