LU80536A1 - Procede de production d'acide 2,5-dicetogluconique - Google Patents
Procede de production d'acide 2,5-dicetogluconique Download PDFInfo
- Publication number
- LU80536A1 LU80536A1 LU80536A LU80536A LU80536A1 LU 80536 A1 LU80536 A1 LU 80536A1 LU 80536 A LU80536 A LU 80536A LU 80536 A LU80536 A LU 80536A LU 80536 A1 LU80536 A1 LU 80536A1
- Authority
- LU
- Luxembourg
- Prior art keywords
- acid
- diketogluconic
- glucose
- fermentation
- medium
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims description 10
- 239000002253 acid Substances 0.000 title claims description 8
- RXMWXENJQAINCC-DMTCNVIQSA-N 2,5-didehydro-D-gluconic acid Chemical compound OCC(=O)[C@@H](O)[C@H](O)C(=O)C(O)=O RXMWXENJQAINCC-DMTCNVIQSA-N 0.000 claims description 21
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims description 15
- 239000008103 glucose Substances 0.000 claims description 15
- 241000589220 Acetobacter Species 0.000 claims description 14
- 238000000855 fermentation Methods 0.000 claims description 12
- 230000004151 fermentation Effects 0.000 claims description 12
- 238000004519 manufacturing process Methods 0.000 claims description 9
- 239000002609 medium Substances 0.000 claims description 7
- VBUYCZFBVCCYFD-JJYYJPOSSA-N 2-dehydro-D-gluconic acid Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)C(=O)C(O)=O VBUYCZFBVCCYFD-JJYYJPOSSA-N 0.000 claims description 5
- 150000007513 acids Chemical class 0.000 claims 1
- 239000006481 glucose medium Substances 0.000 claims 1
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 6
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 4
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 4
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 description 4
- 244000005700 microbiome Species 0.000 description 4
- ZWEHNKRNPOVVGH-UHFFFAOYSA-N 2-Butanone Chemical compound CCC(C)=O ZWEHNKRNPOVVGH-UHFFFAOYSA-N 0.000 description 3
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 3
- 235000010323 ascorbic acid Nutrition 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 2
- 241000209149 Zea Species 0.000 description 2
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 2
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 2
- 230000001580 bacterial effect Effects 0.000 description 2
- 239000001058 brown pigment Substances 0.000 description 2
- 229910000019 calcium carbonate Inorganic materials 0.000 description 2
- 239000004202 carbamide Substances 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 235000005822 corn Nutrition 0.000 description 2
- 235000010350 erythorbic acid Nutrition 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 238000011081 inoculation Methods 0.000 description 2
- 150000004715 keto acids Chemical class 0.000 description 2
- BDAGIHXWWSANSR-UHFFFAOYSA-N methanoic acid Natural products OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 description 2
- 229910000402 monopotassium phosphate Inorganic materials 0.000 description 2
- 229960003512 nicotinic acid Drugs 0.000 description 2
- 235000001968 nicotinic acid Nutrition 0.000 description 2
- 239000011664 nicotinic acid Substances 0.000 description 2
- 229910052757 nitrogen Inorganic materials 0.000 description 2
- 241000894007 species Species 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- PAWQVTBBRAZDMG-UHFFFAOYSA-N 2-(3-bromo-2-fluorophenyl)acetic acid Chemical compound OC(=O)CC1=CC=CC(Br)=C1F PAWQVTBBRAZDMG-UHFFFAOYSA-N 0.000 description 1
- OSWFIVFLDKOXQC-UHFFFAOYSA-N 4-(3-methoxyphenyl)aniline Chemical compound COC1=CC=CC(C=2C=CC(N)=CC=2)=C1 OSWFIVFLDKOXQC-UHFFFAOYSA-N 0.000 description 1
- IZSRJDGCGRAUAR-MROZADKFSA-N 5-dehydro-D-gluconic acid Chemical compound OCC(=O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O IZSRJDGCGRAUAR-MROZADKFSA-N 0.000 description 1
- 239000004254 Ammonium phosphate Substances 0.000 description 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 1
- 241001621835 Frateuria aurantia Species 0.000 description 1
- 241000032681 Gluconacetobacter Species 0.000 description 1
- 241000032686 Gluconacetobacter liquefaciens Species 0.000 description 1
- GRYLNZFGIOXLOG-UHFFFAOYSA-N Nitric acid Chemical compound O[N+]([O-])=O GRYLNZFGIOXLOG-UHFFFAOYSA-N 0.000 description 1
- 239000001888 Peptone Substances 0.000 description 1
- 108010080698 Peptones Proteins 0.000 description 1
- 241001587025 Pseudomonas sesami Species 0.000 description 1
- 229930003268 Vitamin C Natural products 0.000 description 1
- GZCGUPFRVQAUEE-SLPGGIOYSA-N aldehydo-D-glucose Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O GZCGUPFRVQAUEE-SLPGGIOYSA-N 0.000 description 1
- 229910000148 ammonium phosphate Inorganic materials 0.000 description 1
- 235000019289 ammonium phosphates Nutrition 0.000 description 1
- BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 description 1
- 229910052921 ammonium sulfate Inorganic materials 0.000 description 1
- 235000011130 ammonium sulphate Nutrition 0.000 description 1
- 239000012736 aqueous medium Substances 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 239000007900 aqueous suspension Substances 0.000 description 1
- 239000011668 ascorbic acid Substances 0.000 description 1
- 229960005070 ascorbic acid Drugs 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000006227 byproduct Substances 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- MNNHAPBLZZVQHP-UHFFFAOYSA-N diammonium hydrogen phosphate Chemical compound [NH4+].[NH4+].OP([O-])([O-])=O MNNHAPBLZZVQHP-UHFFFAOYSA-N 0.000 description 1
- 229910000396 dipotassium phosphate Inorganic materials 0.000 description 1
- 235000019233 fast yellow AB Nutrition 0.000 description 1
- 235000019253 formic acid Nutrition 0.000 description 1
- 239000010438 granite Substances 0.000 description 1
- 239000003102 growth factor Substances 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 238000004128 high performance liquid chromatography Methods 0.000 description 1
- 101150019110 idi2 gene Proteins 0.000 description 1
- 239000002054 inoculum Substances 0.000 description 1
- 229910017604 nitric acid Inorganic materials 0.000 description 1
- 239000006916 nutrient agar Substances 0.000 description 1
- 238000004816 paper chromatography Methods 0.000 description 1
- 235000019319 peptone Nutrition 0.000 description 1
- 239000013587 production medium Substances 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 230000029305 taxis Effects 0.000 description 1
- 235000019154 vitamin C Nutrition 0.000 description 1
- 239000011718 vitamin C Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/58—Aldonic, ketoaldonic or saccharic acids
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US85295077A | 1977-11-18 | 1977-11-18 | |
| US85295077 | 1977-11-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| LU80536A1 true LU80536A1 (fr) | 1980-06-05 |
Family
ID=25314629
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LU80536A LU80536A1 (fr) | 1977-11-18 | 1978-11-16 | Procede de production d'acide 2,5-dicetogluconique |
Country Status (26)
| Country | Link |
|---|---|
| JP (1) | JPS54145283A (it) |
| AR (1) | AR218348A1 (it) |
| AT (1) | AT363887B (it) |
| AU (1) | AU505434B1 (it) |
| BE (1) | BE872095A (it) |
| BR (1) | BR7807524A (it) |
| CA (1) | CA1119981A (it) |
| CH (1) | CH643592A5 (it) |
| DD (1) | DD140459A5 (it) |
| DE (1) | DE2849393C2 (it) |
| DK (1) | DK152679C (it) |
| ES (1) | ES475216A1 (it) |
| FI (1) | FI782871A7 (it) |
| FR (1) | FR2409304A1 (it) |
| GB (1) | GB2008116B (it) |
| HU (1) | HU175521B (it) |
| IL (1) | IL55969A0 (it) |
| IT (1) | IT1101715B (it) |
| LU (1) | LU80536A1 (it) |
| NL (1) | NL7811353A (it) |
| NO (1) | NO783877L (it) |
| PL (1) | PL118433B1 (it) |
| PT (1) | PT68789A (it) |
| RO (1) | RO75389A (it) |
| SE (1) | SE7809345L (it) |
| ZA (1) | ZA786487B (it) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4316960A (en) * | 1979-09-28 | 1982-02-23 | Pfizer Inc. | Preparation of 2,5-diketogluconic acid |
| FR2820973B1 (fr) | 2001-02-19 | 2003-05-23 | Oreal | Composition comportant de la vitamine c preparee durant l'application, utilisation d'enzymes pour la formation de vitamine c a usage topique et procede de traitement cosmetique |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3234105A (en) * | 1962-09-20 | 1966-02-08 | Takeda Chemical Industries Ltd | Method for producing 2-keto-lgulonic acid |
| US3790444A (en) * | 1971-03-09 | 1974-02-05 | Daiichi Seiyaku Co | Process for preparing diketogluconic acid |
| JPS5135485A (en) * | 1974-09-20 | 1976-03-25 | Shionogi Seiyaku Kk | 22 keto ll guronsan no seizohoho |
-
1978
- 1978-09-05 SE SE7809345A patent/SE7809345L/xx unknown
- 1978-09-13 AU AU39819/78A patent/AU505434B1/en not_active Expired
- 1978-09-20 FI FI782871A patent/FI782871A7/fi not_active IP Right Cessation
- 1978-10-31 CH CH1121978A patent/CH643592A5/fr not_active IP Right Cessation
- 1978-11-02 HU HU78PI647A patent/HU175521B/hu unknown
- 1978-11-03 RO RO7895585A patent/RO75389A/ro unknown
- 1978-11-03 PL PL1978210683A patent/PL118433B1/pl unknown
- 1978-11-03 DD DD78208866A patent/DD140459A5/de unknown
- 1978-11-14 DE DE2849393A patent/DE2849393C2/de not_active Expired
- 1978-11-15 PT PT68789A patent/PT68789A/pt unknown
- 1978-11-16 IT IT29866/78A patent/IT1101715B/it active
- 1978-11-16 GB GB7844723A patent/GB2008116B/en not_active Expired
- 1978-11-16 LU LU80536A patent/LU80536A1/fr unknown
- 1978-11-16 BR BR7807524A patent/BR7807524A/pt unknown
- 1978-11-16 CA CA000316362A patent/CA1119981A/en not_active Expired
- 1978-11-17 DK DK512978A patent/DK152679C/da active
- 1978-11-17 AT AT0823178A patent/AT363887B/de not_active IP Right Cessation
- 1978-11-17 NO NO783877A patent/NO783877L/no unknown
- 1978-11-17 JP JP14215078A patent/JPS54145283A/ja active Granted
- 1978-11-17 BE BE191792A patent/BE872095A/xx unknown
- 1978-11-17 AR AR274472A patent/AR218348A1/es active
- 1978-11-17 ES ES475216A patent/ES475216A1/es not_active Expired
- 1978-11-17 NL NL7811353A patent/NL7811353A/xx not_active Application Discontinuation
- 1978-11-17 ZA ZA00786487A patent/ZA786487B/xx unknown
- 1978-11-17 FR FR7832491A patent/FR2409304A1/fr not_active Withdrawn
- 1978-11-17 IL IL55969A patent/IL55969A0/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FI782871A7 (fi) | 1979-05-19 |
| DK152679B (da) | 1988-04-11 |
| PL210683A1 (pl) | 1979-06-18 |
| PL118433B1 (en) | 1981-10-31 |
| DD140459A5 (de) | 1980-03-05 |
| BE872095A (fr) | 1979-05-17 |
| JPS579357B2 (it) | 1982-02-20 |
| NO783877L (no) | 1979-05-21 |
| DE2849393A1 (de) | 1979-05-23 |
| PT68789A (en) | 1978-12-01 |
| ZA786487B (en) | 1979-10-31 |
| ATA823178A (de) | 1981-02-15 |
| CA1119981A (en) | 1982-03-16 |
| RO75389A (ro) | 1980-11-30 |
| AR218348A1 (es) | 1980-05-30 |
| DK512978A (da) | 1979-05-19 |
| AT363887B (de) | 1981-09-10 |
| FR2409304A1 (fr) | 1979-06-15 |
| GB2008116B (en) | 1982-03-17 |
| AU505434B1 (en) | 1979-11-22 |
| BR7807524A (pt) | 1979-07-24 |
| ES475216A1 (es) | 1979-04-16 |
| SE7809345L (sv) | 1979-05-19 |
| HU175521B (hu) | 1980-08-28 |
| NL7811353A (nl) | 1979-05-22 |
| IL55969A0 (en) | 1979-01-31 |
| GB2008116A (en) | 1979-05-31 |
| DE2849393C2 (de) | 1983-05-05 |
| DK152679C (da) | 1988-08-22 |
| IT1101715B (it) | 1985-10-07 |
| JPS54145283A (en) | 1979-11-13 |
| IT7829866A0 (it) | 1978-11-16 |
| CH643592A5 (fr) | 1984-06-15 |
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